Created
January 1, 2024 06:32
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Converting a 5-day drug schedule to a matching weekly drug schedule
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| import numpy as np | |
| import pk | |
| import seaborn as sns | |
| drug = pk.Drug(hl=8, t_max=1) | |
| # 5 day simulation | |
| conc = drug.concentration( | |
| 60, | |
| 1, | |
| doses={ | |
| 0: 100, | |
| 5: 100, | |
| 10: 100, | |
| 15: 100, | |
| 20: 100, | |
| 25: 100, | |
| 30: 100, | |
| 35: 100, | |
| 40: 100, | |
| 45: 100, | |
| 50: 100, | |
| 55: 100, | |
| 60: 100, | |
| } | |
| ) | |
| # Weekly simulation | |
| weekly_conc = drug.concentration( | |
| 60, | |
| 1, | |
| doses={ | |
| 0: 100, | |
| 7: 100, | |
| 14: 100, | |
| 21: 100, | |
| 28: 100, | |
| 35: 100, | |
| 42: 100, | |
| 49: 100, | |
| 56: 100, | |
| 63: 100, | |
| } | |
| ) | |
| sns.set_style("whitegrid") | |
| sns.lineplot(x=range(0, conc.shape[0]), y=conc) | |
| sns.lineplot(x=range(0, weekly_conc.shape[0]), y=weekly_conc) | |
| # Now adjust the dosage to make them match | |
| # 4 day simulation | |
| new_conc = drug.concentration( | |
| 60, | |
| 1, | |
| doses={ | |
| 0: 125, | |
| 7: 125, | |
| 14: 125, | |
| 21: 125, | |
| 28: 125, | |
| 35: 125, | |
| 42: 125, | |
| 49: 125, | |
| 56: 125, | |
| 63: 125, | |
| } | |
| ) | |
| sns.set_style("whitegrid") | |
| sns.lineplot(x=range(0, conc.shape[0]), y=conc) | |
| sns.lineplot(x=range(0, new_conc.shape[0]), y=new_conc) |
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