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Hep-explorer with PAlt Demo
Raw
index.css
@import url(https://fonts.googleapis.com/css?family=Open+Sans:400, 300);
* {
padding: 0;
margin: 0;
font-family: "Open Sans";
}
#title {
width: 96%;
padding: 0 0 12px 0;
border-bottom: 2px solid lightgray;
margin: 24px 2% 12px 2%;
font-size: 32px;
font-weight: normal;
}
#subtitle {
width: 96%;
margin: 0 2% 12px 2%;
font-size: 24px;
font-weight: lighter;
}
#info {
text-align: center;
color: #004085;
background-color: #cce5ff;
border: 1px solid #b8daff;
padding: 0.5em;
margin: 0 2% 12px 2%;
border-radius: 0.2em;
}
#container {
width: 96%;
margin: 12px 2%;
display: inline-block;
}
.details {
padding: 0.5em;
margin: 0 2% 12px 2%;
}
Raw
index.html
<html>
<head>
<title>Hepatic Safety Explorer - Example 5</title>
<meta http-equiv="Content-Type" content="text/html; charset = utf-8" />
<script type="text/javascript" src="https://d3js.org/d3.v3.min.js"></script>
<script
type="text/javascript"
src="https://cdn.jsdelivr.net/gh/RhoInc/Webcharts@1/build/webcharts.min.js"
></script>
<script type="text/javascript" src="https://cdn.jsdelivr.net/gh/safetyGraphics/hep-explorer@palt/hepexplorer.js"></script>
<link
type="text/css"
rel="stylesheet"
href="https://cdn.jsdelivr.net/gh/RhoInc/Webcharts@1/css/webcharts.min.css"
/>
<link type="text/css" rel="stylesheet" href="index.css" />
</head>
<body>
<div id="title">Hepatic Safety Explorer</div>
<div id="subtitle">Example 5 - Adding P<sub>ALT</sub></div>
<div class="details">
In this example, P<sub>ALT</sub> is shown for participants with elevated
Alanine Aminotransferase (U/L). P<sub>ALT</sub> shows promise in
predicting the percentage hepatocyte loss on the basis of the maximum
value and the AUC of serum ALT observed during a DILI event. For more
details see
<a href="https://www.ncbi.nlm.nih.gov/pubmed/30303523"
>A Rapid Method to Estimate Hepatocyte Loss Due to Drug-Induced Liver
Injury</a
>
by Chung et al.';
</div>
<div id="info">
This is a demo page for the interactive Hepatic Explorer created by the
ASA-DIA Interactive Safety Graphics working group. Code, details and
documentation are available on
<a href="https://github.com/SafetyGraphics/hep-explorer">github</a>.
</div>
<div id="container"></div>
</body>
<script>
const settings = {
calculate_palt: true,
paltFlag: {
value_col: "PALT",
values: ["1"]
},
max_width: 600,
value_col: "AVAL",
measure_col: "PARAM",
visit_col: "VISIT",
visitn_col: "VISITNUM",
studyday_col: "ADY",
normal_col_low: "A1LO",
normal_col_high: "A1HI",
id_col: "USUBJID",
group_cols: ["TRTA", "RACE", "AGEGR1"],
r_ratio_filter: true,
filters: [
{
value_col: "TRTA",
label: "Treatment"
},
{
value_col: "ALT_ELEVATED",
label: "ALT Elevated?"
}
],
measure_values: {
ALT: "Alanine Aminotransferase (U/L)",
AST: "Aspartate Aminotransferase (U/L)",
TB: "Bilirubin (umol/L)",
ALP: "Alkaline Phosphatase (U/L)"
},
baseline: {
value_col: "AVISIT",
values: ["Baseline"]
}
};
const chart = hepexplorer("#container", settings);
d3.csv("palt_adlbc.csv", function(data) {
data.forEach(function(d) {
d.EPOCH = +d.VISITNUM > 1 ? "Analysis" : "Baseline";
});
chart.init(data);
});
</script>
</html>
Raw
palt_adlbc.csv
We can't make this file beautiful and searchable because it's too large.
STUDYID,SUBJID,USUBJID,TRTP,TRTPN,TRTA,TRTAN,TRTSDT,TRTEDT,AGE,AGEGR1,AGEGR1N,RACE,RACEN,SEX,COMP24FL,DSRAEFL,SAFFL,AVISIT,AVISITN,ADY,ADT,VISIT,VISITNUM,PARAM,PARAMCD,PARAMN,PARCAT1,AVAL,BASE,CHG,A1LO,A1HI,R2A1LO,R2A1HI,BR2A1LO,BR2A1HI,ANL01FL,ALBTRVAL,ANRIND,BNRIND,ABLFL,AENTMTFL,LBSEQ,LBNRIND,LBSTRESN,PALT,ALT_ELEVATED
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,12/26/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,20,NORMAL,4.5,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,12/26/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,7,NORMAL,10.26,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,12/26/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,34,34,,35,115,0.971428571,0.295652174,0.971428571,0.295652174,,138.5,N,N,Y,,2,LOW,34,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,12/26/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,27,,6,34,4.5,0.794117647,4.5,0.794117647,,24,N,N,Y,,3,NORMAL,27,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,12/26/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,40,40,,9,34,4.444444444,1.176470588,4.444444444,1.176470588,,35.5,N,N,Y,,5,HIGH,40,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,15,1/16/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.5,-0.1,3.4,5.4,1.294117647,0.814814815,1.323529412,0.833333333,,3.7,N,N,,,57,NORMAL,4.4,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,15,1/16/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,44,NORMAL,8.55,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,15,1/16/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,34,16,35,115,1.428571429,0.434782609,0.971428571,0.295652174,,122.5,N,N,,,40,NORMAL,50,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,15,1/16/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,41,27,14,6,34,6.833333333,1.205882353,4.5,0.794117647,Y,38,N,N,,,41,HIGH,41,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,15,1/16/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,33,40,-7,9,34,3.666666667,0.970588235,4.444444444,1.176470588,,28.5,N,N,,,42,NORMAL,33,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,29,1/30/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.5,4.5,0,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,,,91,NORMAL,4.5,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,29,1/30/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,79,NORMAL,6.84,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,29,1/30/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,41,34,7,35,115,1.171428571,0.356521739,0.971428571,0.295652174,Y,131.5,N,N,,,75,NORMAL,41,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,29,1/30/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,27,-9,6,34,3,0.529411765,4.5,0.794117647,,33,N,N,,,76,NORMAL,18,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,29,1/30/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,40,-19,9,34,2.333333333,0.617647059,4.444444444,1.176470588,,30,N,N,,,77,NORMAL,21,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,42,2/12/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.6,4.5,0.1,3.4,5.4,1.352941176,0.851851852,1.323529412,0.833333333,,3.5,N,N,,,121,NORMAL,4.6,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,42,2/12/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,5.13,10.26,-5.13,3,21,1.71,0.244285714,3.42,0.488571429,Y,26.37,N,N,,,109,NORMAL,5.13,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,42,2/12/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,43,34,9,35,115,1.228571429,0.373913043,0.971428571,0.295652174,,129.5,N,N,,,105,NORMAL,43,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,42,2/12/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,27,-1,6,34,4.333333333,0.764705882,4.5,0.794117647,,25,N,N,,,106,NORMAL,26,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,42,2/12/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,40,-14,9,34,2.888888889,0.764705882,4.444444444,1.176470588,,25,N,N,,,107,NORMAL,26,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,63,3/5/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,151,NORMAL,4.1,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,63,3/5/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,139,NORMAL,8.55,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,63,3/5/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,47,34,13,35,115,1.342857143,0.408695652,0.971428571,0.295652174,,125.5,N,N,,,135,NORMAL,47,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,63,3/5/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,27,-5,6,34,3.666666667,0.647058824,4.5,0.794117647,,29,N,N,,,136,NORMAL,22,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,63,3/5/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,40,-19,9,34,2.333333333,0.617647059,4.444444444,1.176470588,,30,N,N,,,137,NORMAL,21,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,84,3/26/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.6,4.5,-0.9,3.4,5.4,1.058823529,0.666666667,1.323529412,0.833333333,Y,4.5,N,N,,,182,NORMAL,3.6,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,84,3/26/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,169,NORMAL,6.84,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,84,3/26/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,34,19,35,115,1.514285714,0.460869565,0.971428571,0.295652174,,119.5,N,N,,,165,NORMAL,53,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,84,3/26/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,27,0,6,34,4.5,0.794117647,4.5,0.794117647,,24,N,N,,,166,NORMAL,27,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,84,3/26/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,40,-18,9,34,2.444444444,0.647058824,4.444444444,1.176470588,,29,N,N,,,167,NORMAL,22,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,126,5/7/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,216,NORMAL,4.1,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,126,5/7/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,204,NORMAL,6.84,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,126,5/7/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,41,34,7,35,115,1.171428571,0.356521739,0.971428571,0.295652174,,131.5,N,N,,,200,NORMAL,41,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,126,5/7/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,27,-10,6,34,2.833333333,0.5,4.5,0.794117647,,34,N,N,,,201,NORMAL,17,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,126,5/7/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,40,-17,9,34,2.555555556,0.676470588,4.444444444,1.176470588,,28,N,N,,,202,NORMAL,23,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,140,5/21/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,,246,NORMAL,4.3,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,140,5/21/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,234,NORMAL,6.84,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,140,5/21/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,45,34,11,35,115,1.285714286,0.391304348,0.971428571,0.295652174,,127.5,N,N,,,230,NORMAL,45,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,140,5/21/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,27,-6,6,34,3.5,0.617647059,4.5,0.794117647,,30,N,N,,,231,NORMAL,21,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,140,5/21/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,40,-21,9,34,2.111111111,0.558823529,4.444444444,1.176470588,Y,32,N,N,,,232,NORMAL,19,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,168,6/18/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,Y,277,NORMAL,4.1,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,168,6/18/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,Y,277,NORMAL,4.1,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,168,6/18/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,Y,264,NORMAL,6.84,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,168,6/18/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,Y,264,NORMAL,6.84,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,168,6/18/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,34,12,35,115,1.314285714,0.4,0.971428571,0.295652174,,126.5,N,N,,Y,260,NORMAL,46,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,168,6/18/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,34,12,35,115,1.314285714,0.4,0.971428571,0.295652174,,126.5,N,N,,Y,260,NORMAL,46,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,168,6/18/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,27,-4,6,34,3.833333333,0.676470588,4.5,0.794117647,,28,N,N,,Y,261,NORMAL,23,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,168,6/18/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,27,-4,6,34,3.833333333,0.676470588,4.5,0.794117647,,28,N,N,,Y,261,NORMAL,23,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,168,6/18/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,40,-17,9,34,2.555555556,0.676470588,4.444444444,1.176470588,,28,N,N,,Y,262,NORMAL,23,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,168,6/18/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,40,-17,9,34,2.555555556,0.676470588,4.444444444,1.176470588,,28,N,N,,Y,262,NORMAL,23,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 26,26,182,7/2/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.5,4.5,0,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,,,311,NORMAL,4.5,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 26,26,182,7/2/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,5.13,10.26,-5.13,3,21,1.71,0.244285714,3.42,0.488571429,,26.37,N,N,,,299,NORMAL,5.13,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 26,26,182,7/2/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,44,34,10,35,115,1.257142857,0.382608696,0.971428571,0.295652174,,128.5,N,N,,,295,NORMAL,44,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 26,26,182,7/2/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,27,-4,6,34,3.833333333,0.676470588,4.5,0.794117647,,28,N,N,,,296,NORMAL,23,0,No
CDISCPILOT01,1015,01-701-1015,Placebo,0,Placebo,0,1/2/14,7/2/14,63,<65,1,WHITE,1,F,Y,,Y, Week 26,26,182,7/2/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,40,-21,9,34,2.111111111,0.558823529,4.444444444,1.176470588,,32,N,N,,,297,NORMAL,19,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,7/22/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.9,4.9,,3.4,5.4,1.441176471,0.907407407,1.441176471,0.907407407,,3.2,N,N,Y,,19,NORMAL,4.9,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,7/22/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,7/22/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,98,,35,115,2.8,0.852173913,2.8,0.852173913,,80.5,N,N,Y,,2,NORMAL,98,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,7/22/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,,6,43,3.833333333,0.534883721,3.833333333,0.534883721,,41.5,N,N,Y,,3,NORMAL,23,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,7/22/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,Y,,4,NORMAL,21,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,23,8/27/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,4.9,-0.1,3.4,5.4,1.411764706,0.888888889,1.441176471,0.907407407,,3.3,N,N,,,56,NORMAL,4.8,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,23,8/27/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,Y,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,23,8/27/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,98,-8,35,115,2.571428571,0.782608696,2.8,0.852173913,Y,82.5,N,N,,,39,NORMAL,90,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,23,8/27/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,30,23,7,6,43,5,0.697674419,3.833333333,0.534883721,,34.5,N,N,,,40,NORMAL,30,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,23,8/27/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,21,4,11,36,2.272727273,0.694444444,1.909090909,0.583333333,Y,29,N,N,,,41,NORMAL,25,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,29,9/2/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,4.9,-0.2,3.4,5.4,1.382352941,0.87037037,1.441176471,0.907407407,Y,3.4,N,N,,Y,91,NORMAL,4.7,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,29,9/2/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,4.9,-0.2,3.4,5.4,1.382352941,0.87037037,1.441176471,0.907407407,Y,3.4,N,N,,Y,91,NORMAL,4.7,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,29,9/2/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,78,NORMAL,8.55,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,29,9/2/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,78,NORMAL,8.55,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,29,9/2/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,99,98,1,35,115,2.828571429,0.860869565,2.8,0.852173913,,81.5,N,N,,Y,74,NORMAL,99,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,29,9/2/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,99,98,1,35,115,2.828571429,0.860869565,2.8,0.852173913,,81.5,N,N,,Y,74,NORMAL,99,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,29,9/2/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,38,23,15,6,43,6.333333333,0.88372093,3.833333333,0.534883721,Y,35,N,N,,Y,75,NORMAL,38,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,29,9/2/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,38,23,15,6,43,6.333333333,0.88372093,3.833333333,0.534883721,Y,35,N,N,,Y,75,NORMAL,38,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,29,9/2/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,21,9,11,36,2.727272727,0.833333333,1.909090909,0.583333333,,24.5,N,N,,Y,76,NORMAL,30,0,No
CDISCPILOT01,1023,01-701-1023,Placebo,0,Placebo,0,8/5/12,9/1/12,64,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,29,9/2/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,21,9,11,36,2.727272727,0.833333333,1.909090909,0.583333333,,24.5,N,N,,Y,76,NORMAL,30,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-8,7/11/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.4,4.4,,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,Y,,19,NORMAL,4.4,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-8,7/11/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,18.81,18.81,,3,21,6.27,0.895714286,6.27,0.895714286,,17.31,N,N,Y,,6,NORMAL,18.81,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-8,7/11/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,44,44,,35,115,1.257142857,0.382608696,1.257142857,0.382608696,,128.5,N,N,Y,,2,NORMAL,44,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-8,7/11/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,26,,6,35,4.333333333,0.742857143,4.333333333,0.742857143,,26.5,N,N,Y,,3,NORMAL,26,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-8,7/11/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,Y,,4,NORMAL,24,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,14,8/1/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.4,0.2,3.4,5.4,1.352941176,0.851851852,1.294117647,0.814814815,,3.5,N,N,,,56,NORMAL,4.6,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,14,8/1/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,18.81,-6.84,3,21,3.99,0.57,6.27,0.895714286,Y,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,14,8/1/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,44,2,35,115,1.314285714,0.4,1.257142857,0.382608696,,126.5,N,N,,,39,NORMAL,46,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,14,8/1/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,30,26,4,6,35,5,0.857142857,4.333333333,0.742857143,,27,N,N,,,40,NORMAL,30,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,14,8/1/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,,41,NORMAL,23,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,8/14/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.4,0.2,3.4,5.4,1.352941176,0.851851852,1.294117647,0.814814815,,3.5,N,N,,,90,NORMAL,4.6,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,8/14/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,18.81,-5.13,3,21,4.56,0.651428571,6.27,0.895714286,,17.82,N,N,,,78,NORMAL,13.68,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,8/14/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,38,44,-6,35,115,1.085714286,0.330434783,1.257142857,0.382608696,,134.5,N,N,,,74,NORMAL,38,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,8/14/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,26,3,6,35,4.833333333,0.828571429,4.333333333,0.742857143,,26,N,N,,,75,NORMAL,29,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,8/14/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,0,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,,,76,NORMAL,24,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,8/29/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,120,NORMAL,4.4,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,8/29/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,11.97,18.81,-6.84,3,21,3.99,0.57,6.27,0.895714286,,19.53,N,N,,,108,NORMAL,11.97,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,8/29/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,40,44,-4,35,115,1.142857143,0.347826087,1.257142857,0.382608696,,132.5,N,N,,,104,NORMAL,40,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,8/29/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,32,26,6,6,35,5.333333333,0.914285714,4.333333333,0.742857143,,29,N,N,,,105,NORMAL,32,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,8/29/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,24,2,11,36,2.363636364,0.722222222,2.181818182,0.666666667,,28,N,N,,,106,NORMAL,26,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,9/10/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4,4.4,-0.4,3.4,5.4,1.176470588,0.740740741,1.294117647,0.814814815,Y,4.1,N,N,,,150,NORMAL,4,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,9/10/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,13.68,18.81,-5.13,3,21,4.56,0.651428571,6.27,0.895714286,,17.82,N,N,,,138,NORMAL,13.68,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,9/10/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,40,44,-4,35,115,1.142857143,0.347826087,1.257142857,0.382608696,,132.5,N,N,,,134,NORMAL,40,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,9/10/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,26,7,6,35,5.5,0.942857143,4.333333333,0.742857143,,30,N,N,,,135,NORMAL,33,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,9/10/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,24,4,11,36,2.545454545,0.777777778,2.181818182,0.666666667,,26,N,N,,,136,NORMAL,28,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,83,10/9/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,181,NORMAL,4.4,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,83,10/9/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,13.68,18.81,-5.13,3,21,4.56,0.651428571,6.27,0.895714286,,17.82,N,N,,,168,NORMAL,13.68,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,83,10/9/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,41,44,-3,35,115,1.171428571,0.356521739,1.257142857,0.382608696,,131.5,N,N,,,164,NORMAL,41,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,83,10/9/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,26,3,6,35,4.833333333,0.828571429,4.333333333,0.742857143,,26,N,N,,,165,NORMAL,29,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,83,10/9/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,24,4,11,36,2.545454545,0.777777778,2.181818182,0.666666667,,26,N,N,,,166,NORMAL,28,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,111,11/6/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,216,NORMAL,4.2,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,111,11/6/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,11.97,18.81,-6.84,3,21,3.99,0.57,6.27,0.895714286,,19.53,N,N,,,204,NORMAL,11.97,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,111,11/6/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,36,44,-8,35,115,1.028571429,0.313043478,1.257142857,0.382608696,Y,136.5,N,N,,,199,NORMAL,36,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,111,11/6/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,26,-2,6,35,4,0.685714286,4.333333333,0.742857143,,28.5,N,N,,,200,NORMAL,24,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,111,11/6/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,24,-6,11,36,1.636363636,0.5,2.181818182,0.666666667,Y,36,N,N,,,202,NORMAL,18,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,139,12/4/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,248,NORMAL,4.2,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,139,12/4/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,13.68,18.81,-5.13,3,21,4.56,0.651428571,6.27,0.895714286,,17.82,N,N,,,236,NORMAL,13.68,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,139,12/4/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,43,44,-1,35,115,1.228571429,0.373913043,1.257142857,0.382608696,,129.5,N,N,,,231,NORMAL,43,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,139,12/4/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,26,-4,6,35,3.666666667,0.628571429,4.333333333,0.742857143,Y,30.5,N,N,,,232,NORMAL,22,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,139,12/4/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,24,-3,11,36,1.909090909,0.583333333,2.181818182,0.666666667,,33,N,N,,,234,NORMAL,21,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,172,1/6/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.4,0.2,3.4,5.4,1.352941176,0.851851852,1.294117647,0.814814815,,3.5,N,N,,Y,279,NORMAL,4.6,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,172,1/6/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.4,0.2,3.4,5.4,1.352941176,0.851851852,1.294117647,0.814814815,,3.5,N,N,,Y,279,NORMAL,4.6,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,172,1/6/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,15.39,18.81,-3.42,3,21,5.13,0.732857143,6.27,0.895714286,,16.11,N,N,,Y,266,NORMAL,15.39,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,172,1/6/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,15.39,18.81,-3.42,3,21,5.13,0.732857143,6.27,0.895714286,,16.11,N,N,,Y,266,NORMAL,15.39,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,172,1/6/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,47,44,3,35,115,1.342857143,0.408695652,1.257142857,0.382608696,,125.5,N,N,,Y,262,NORMAL,47,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,172,1/6/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,47,44,3,35,115,1.342857143,0.408695652,1.257142857,0.382608696,,125.5,N,N,,Y,262,NORMAL,47,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,172,1/6/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,26,-2,6,35,4,0.685714286,4.333333333,0.742857143,,28.5,N,N,,Y,263,NORMAL,24,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,172,1/6/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,26,-2,6,35,4,0.685714286,4.333333333,0.742857143,,28.5,N,N,,Y,263,NORMAL,24,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,172,1/6/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,Y,264,NORMAL,23,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,172,1/6/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,Y,264,NORMAL,23,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,180,1/14/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,315,NORMAL,4.4,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,180,1/14/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,13.68,18.81,-5.13,3,21,4.56,0.651428571,6.27,0.895714286,,17.82,N,N,,,303,NORMAL,13.68,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,180,1/14/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,40,44,-4,35,115,1.142857143,0.347826087,1.257142857,0.382608696,,132.5,N,N,,,299,NORMAL,40,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,180,1/14/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,26,0,6,35,4.333333333,0.742857143,4.333333333,0.742857143,,26.5,N,N,,,300,NORMAL,26,0,No
CDISCPILOT01,1028,01-701-1028,Xanomeline High Dose,81,Xanomeline High Dose,81,7/19/13,1/14/14,71,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,180,1/14/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,0,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,,,301,NORMAL,24,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-8,3/10/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-8,3/10/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-8,3/10/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,67,,35,115,1.914285714,0.582608696,1.914285714,0.582608696,,105.5,N,N,Y,,2,NORMAL,67,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-8,3/10/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,35,2.666666667,0.457142857,2.666666667,0.457142857,,36.5,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-8,3/10/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,11,36,1.818181818,0.555555556,1.818181818,0.555555556,,34,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,4/1/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4.1,0.1,3.4,5.4,1.235294118,0.777777778,1.205882353,0.759259259,,3.9,N,N,,,56,NORMAL,4.2,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,4/1/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,13.68,-6.84,3,21,2.28,0.325714286,4.56,0.651428571,Y,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,4/1/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,67,22,35,115,2.542857143,0.773913043,1.914285714,0.582608696,,83.5,N,N,,,39,NORMAL,89,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,4/1/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,35,16,19,6,35,5.833333333,1,2.666666667,0.457142857,,32,N,N,,,40,NORMAL,35,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,4/1/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,20,6,11,36,2.363636364,0.722222222,1.818181818,0.555555556,,28,N,N,,,41,NORMAL,26,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 4,4,28,4/14/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,4.1,-0.2,3.4,5.4,1.147058824,0.722222222,1.205882353,0.759259259,Y,4.2,N,N,,Y,91,NORMAL,3.9,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,28,4/14/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,4.1,-0.2,3.4,5.4,1.147058824,0.722222222,1.205882353,0.759259259,Y,4.2,N,N,,Y,91,NORMAL,3.9,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 4,4,28,4/14/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,15.39,13.68,1.71,3,21,5.13,0.732857143,4.56,0.651428571,,16.11,N,N,,Y,78,NORMAL,15.39,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,28,4/14/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,15.39,13.68,1.71,3,21,5.13,0.732857143,4.56,0.651428571,,16.11,N,N,,Y,78,NORMAL,15.39,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 4,4,28,4/14/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,67,9,35,115,2.171428571,0.660869565,1.914285714,0.582608696,Y,96.5,N,N,,Y,74,NORMAL,76,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,28,4/14/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,67,9,35,115,2.171428571,0.660869565,1.914285714,0.582608696,Y,96.5,N,N,,Y,74,NORMAL,76,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 4,4,28,4/14/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,35,2.333333333,0.4,2.666666667,0.457142857,Y,38.5,N,N,,Y,75,NORMAL,14,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,28,4/14/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,35,2.333333333,0.4,2.666666667,0.457142857,Y,38.5,N,N,,Y,75,NORMAL,14,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y, Week 4,4,28,4/14/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,11,36,1.818181818,0.555555556,1.818181818,0.555555556,Y,34,N,N,,Y,76,NORMAL,20,0,No
CDISCPILOT01,1033,01-701-1033,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/18/14,3/31/14,74,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,28,4/14/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,11,36,1.818181818,0.555555556,1.818181818,0.555555556,Y,34,N,N,,Y,76,NORMAL,20,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-7,6/24/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.4,4.4,,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,Y,,20,NORMAL,4.4,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-7,6/24/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,7,NORMAL,10.26,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-7,6/24/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,41,41,,35,115,1.171428571,0.356521739,1.171428571,0.356521739,,131.5,N,N,Y,,2,NORMAL,41,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-7,6/24/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,,6,32,2.5,0.46875,2.5,0.46875,,33,N,N,Y,,3,NORMAL,15,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-7,6/24/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,,9,34,2.555555556,0.676470588,2.555555556,0.676470588,,28,N,N,Y,,5,NORMAL,23,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,7/15/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.4,0.2,3.4,5.4,1.352941176,0.851851852,1.294117647,0.814814815,,3.5,N,N,,,57,NORMAL,4.6,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,7/15/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,44,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,7/15/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,34,41,-7,35,115,0.971428571,0.295652174,1.171428571,0.356521739,,138.5,N,N,,,40,LOW,34,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,7/15/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,15,4,6,32,3.166666667,0.59375,2.5,0.46875,,29,N,N,,,41,NORMAL,19,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,7/15/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,0,9,34,2.555555556,0.676470588,2.555555556,0.676470588,,28,N,N,,,42,NORMAL,23,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,29,7/29/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,93,NORMAL,4.4,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,29,7/29/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,81,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,29,7/29/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,36,41,-5,35,115,1.028571429,0.313043478,1.171428571,0.356521739,,136.5,N,N,,,76,NORMAL,36,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,29,7/29/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,15,6,6,32,3.5,0.65625,2.5,0.46875,,27,N,N,,,77,NORMAL,21,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,29,7/29/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,23,2,9,34,2.777777778,0.735294118,2.555555556,0.676470588,,26,N,N,,,79,NORMAL,25,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,8/11/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.4,-0.3,3.4,5.4,1.205882353,0.759259259,1.294117647,0.814814815,Y,4,N,N,,,124,NORMAL,4.1,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,8/11/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,112,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,8/11/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,33,41,-8,35,115,0.942857143,0.286956522,1.171428571,0.356521739,,139.5,N,N,,,107,LOW,33,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,8/11/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,0,6,32,2.5,0.46875,2.5,0.46875,Y,33,N,N,,,108,NORMAL,15,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,8/11/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,23,-4,9,34,2.111111111,0.558823529,2.555555556,0.676470588,,32,N,N,,,110,NORMAL,19,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,8/26/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.8,4.4,0.4,3.4,5.4,1.411764706,0.888888889,1.294117647,0.814814815,,3.3,N,N,,,154,NORMAL,4.8,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,8/26/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,142,NORMAL,8.55,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,8/26/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,29,41,-12,35,115,0.828571429,0.252173913,1.171428571,0.356521739,Y,143.5,N,N,,,138,LOW,29,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,8/26/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,15,9,6,32,4,0.75,2.5,0.46875,,24,N,N,,,139,NORMAL,24,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,8/26/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,23,3,9,34,2.888888889,0.764705882,2.555555556,0.676470588,,25,N,N,,,140,NORMAL,26,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,87,9/25/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,185,NORMAL,4.2,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,87,9/25/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,172,NORMAL,8.55,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,87,9/25/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,34,41,-7,35,115,0.971428571,0.295652174,1.171428571,0.356521739,,138.5,N,N,,,168,LOW,34,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,87,9/25/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,15,5,6,32,3.333333333,0.625,2.5,0.46875,,28,N,N,,,169,NORMAL,20,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,87,9/25/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,0,9,34,2.555555556,0.676470588,2.555555556,0.676470588,,28,N,N,,,170,NORMAL,23,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,113,10/21/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.7,4.4,0.3,3.4,5.4,1.382352941,0.87037037,1.294117647,0.814814815,,3.4,N,N,,,219,NORMAL,4.7,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,113,10/21/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,207,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,113,10/21/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,34,41,-7,35,115,0.971428571,0.295652174,1.171428571,0.356521739,,138.5,N,N,,,203,LOW,34,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,113,10/21/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,15,6,6,32,3.5,0.65625,2.5,0.46875,,27,N,N,,,204,NORMAL,21,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,113,10/21/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,23,-2,9,34,2.333333333,0.617647059,2.555555556,0.676470588,,30,N,N,,,205,NORMAL,21,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,141,11/18/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.5,4.4,0.1,3.4,5.4,1.323529412,0.833333333,1.294117647,0.814814815,,3.6,N,N,,,250,NORMAL,4.5,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,141,11/18/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,10.26,-5.13,3,21,1.71,0.244285714,3.42,0.488571429,Y,26.37,N,N,,,238,NORMAL,5.13,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,141,11/18/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,31,41,-10,35,115,0.885714286,0.269565217,1.171428571,0.356521739,,141.5,N,N,,,234,LOW,31,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,141,11/18/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,15,8,6,32,3.833333333,0.71875,2.5,0.46875,,25,N,N,,,235,NORMAL,23,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,141,11/18/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,23,-1,9,34,2.444444444,0.647058824,2.555555556,0.676470588,,29,N,N,,,236,NORMAL,22,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,12/17/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.4,0.1,3.4,5.4,1.323529412,0.833333333,1.294117647,0.814814815,,3.6,N,N,,Y,282,NORMAL,4.5,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,12/17/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.4,0.1,3.4,5.4,1.323529412,0.833333333,1.294117647,0.814814815,,3.6,N,N,,Y,282,NORMAL,4.5,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,12/17/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,Y,269,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,12/17/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,Y,269,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,12/17/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,40,41,-1,35,115,1.142857143,0.347826087,1.171428571,0.356521739,,132.5,N,N,,Y,265,NORMAL,40,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,12/17/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,40,41,-1,35,115,1.142857143,0.347826087,1.171428571,0.356521739,,132.5,N,N,,Y,265,NORMAL,40,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,12/17/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,0,6,32,2.5,0.46875,2.5,0.46875,,33,N,N,,Y,266,NORMAL,15,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,12/17/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,0,6,32,2.5,0.46875,2.5,0.46875,,33,N,N,,Y,266,NORMAL,15,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,12/17/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,23,-6,9,34,1.888888889,0.5,2.555555556,0.676470588,Y,34,N,N,,Y,267,NORMAL,17,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,12/17/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,23,-6,9,34,1.888888889,0.5,2.555555556,0.676470588,Y,34,N,N,,Y,267,NORMAL,17,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,12/30/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,318,NORMAL,4.2,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,12/30/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,306,NORMAL,6.84,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,12/30/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,27,41,-14,35,115,0.771428571,0.234782609,1.171428571,0.356521739,,145.5,N,N,,,301,LOW,27,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,12/30/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,15,3,6,32,3,0.5625,2.5,0.46875,,30,N,N,,,302,NORMAL,18,0,No
CDISCPILOT01,1034,01-701-1034,Xanomeline High Dose,81,Xanomeline High Dose,81,7/1/14,12/30/14,77,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,12/30/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,23,-2,9,34,2.333333333,0.617647059,2.555555556,0.676470588,,30,N,N,,,304,NORMAL,21,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-21,1/22/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-21,1/22/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-21,1/22/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,78,,35,115,2.228571429,0.67826087,2.228571429,0.67826087,,94.5,N,N,Y,,2,NORMAL,78,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-21,1/22/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,22,,6,32,3.666666667,0.6875,3.666666667,0.6875,,26,N,N,Y,,3,NORMAL,22,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-21,1/22/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,Y,4.2,N,N,,,56,NORMAL,3.9,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,78,-11,35,115,1.914285714,0.582608696,2.228571429,0.67826087,Y,105.5,N,N,,,39,NORMAL,67,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,22,-6,6,32,2.666666667,0.5,3.666666667,0.6875,Y,32,N,N,,,40,NORMAL,16,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,25,-4,9,34,2.333333333,0.617647059,2.777777778,0.735294118,Y,30,N,N,,,41,NORMAL,21,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,27,3/10/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,,4.2,N,N,,Y,90,NORMAL,3.9,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,27,3/10/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,,4.2,N,N,,Y,90,NORMAL,3.9,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,27,3/10/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,78,NORMAL,6.84,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,27,3/10/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,78,NORMAL,6.84,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,27,3/10/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,71,78,-7,35,115,2.028571429,0.617391304,2.228571429,0.67826087,,101.5,N,N,,Y,74,NORMAL,71,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,27,3/10/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,71,78,-7,35,115,2.028571429,0.617391304,2.228571429,0.67826087,,101.5,N,N,,Y,74,NORMAL,71,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,27,3/10/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,22,-2,6,32,3.333333333,0.625,3.666666667,0.6875,,28,N,N,,Y,75,NORMAL,20,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,27,3/10/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,22,-2,6,32,3.333333333,0.625,3.666666667,0.6875,,28,N,N,,Y,75,NORMAL,20,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,27,3/10/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,25,-1,9,34,2.666666667,0.705882353,2.777777778,0.735294118,,27,N,N,,Y,76,NORMAL,24,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,27,3/10/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,25,-1,9,34,2.666666667,0.705882353,2.777777778,0.735294118,,27,N,N,,Y,76,NORMAL,24,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, .,,55,4/7/13,UNSCHEDULED 6.1,6.1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,124,NORMAL,6.84,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, .,,55,4/7/13,UNSCHEDULED 6.1,6.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,78,-3,35,115,2.142857143,0.652173913,2.228571429,0.67826087,,97.5,N,N,,,121,NORMAL,75,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, .,,55,4/7/13,UNSCHEDULED 6.1,6.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,22,-5,6,32,2.833333333,0.53125,3.666666667,0.6875,,31,N,N,,,122,NORMAL,17,0,No
CDISCPILOT01,1047,01-701-1047,Placebo,0,Placebo,0,2/12/13,3/9/13,85,>80,3,WHITE,1,F,N,Y,Y, .,,55,4/7/13,UNSCHEDULED 6.1,6.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,25,-4,9,34,2.333333333,0.617647059,2.777777778,0.735294118,,30,N,N,,,123,NORMAL,21,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,12/23/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,19,NORMAL,4.6,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,12/23/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,12/23/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,56,,35,115,1.6,0.486956522,1.6,0.486956522,,116.5,N,N,Y,,2,NORMAL,56,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,12/23/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,43,2.666666667,0.372093023,2.666666667,0.372093023,,48.5,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,12/23/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,,11,36,1.727272727,0.527777778,1.727272727,0.527777778,,35,N,N,Y,,4,NORMAL,19,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,1/15/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,4.6,0.2,3.4,5.4,1.411764706,0.888888889,1.352941176,0.851851852,,3.3,N,N,,,56,NORMAL,4.8,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,1/15/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,1/15/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,54,56,-2,35,115,1.542857143,0.469565217,1.6,0.486956522,,118.5,N,N,,,39,NORMAL,54,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,1/15/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,16,8,6,43,4,0.558139535,2.666666667,0.372093023,,40.5,N,N,,,40,NORMAL,24,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,1/15/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,19,2,11,36,1.909090909,0.583333333,1.727272727,0.527777778,,33,N,N,,,41,NORMAL,21,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,1/29/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.8,4.6,0.2,3.4,5.4,1.411764706,0.888888889,1.352941176,0.851851852,,3.3,N,N,,,90,NORMAL,4.8,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,1/29/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,1/29/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,49,56,-7,35,115,1.4,0.426086957,1.6,0.486956522,,123.5,N,N,,,74,NORMAL,49,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,1/29/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,16,1,6,43,2.833333333,0.395348837,2.666666667,0.372093023,,47.5,N,N,,,75,NORMAL,17,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,1/29/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,19,-3,11,36,1.454545455,0.444444444,1.727272727,0.527777778,Y,38,N,N,,,76,NORMAL,16,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,2/11/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.6,4.6,0,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,,,120,NORMAL,4.6,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,2/11/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,2/11/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,48,56,-8,35,115,1.371428571,0.417391304,1.6,0.486956522,Y,124.5,N,N,,,104,NORMAL,48,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,2/11/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,43,2.333333333,0.325581395,2.666666667,0.372093023,,50.5,N,N,,,105,NORMAL,14,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,42,2/11/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,0,11,36,1.727272727,0.527777778,1.727272727,0.527777778,,35,N,N,,,106,NORMAL,19,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,2/26/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,5,4.6,0.4,3.4,5.4,1.470588235,0.925925926,1.352941176,0.851851852,,3.3,N,N,,,150,NORMAL,5,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,2/26/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,2/26/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,49,56,-7,35,115,1.4,0.426086957,1.6,0.486956522,,123.5,N,N,,,134,NORMAL,49,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,2/26/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,43,3,0.418604651,2.666666667,0.372093023,,46.5,N,N,,,135,NORMAL,18,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,2/26/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,19,-1,11,36,1.636363636,0.5,1.727272727,0.527777778,,36,N,N,,,136,NORMAL,18,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,3/26/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,,181,NORMAL,4.2,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,3/26/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,168,NORMAL,6.84,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,3/26/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,56,-3,35,115,1.514285714,0.460869565,1.6,0.486956522,,119.5,N,N,,,164,NORMAL,53,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,3/26/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,43,2.333333333,0.325581395,2.666666667,0.372093023,,50.5,N,N,,,165,NORMAL,14,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,3/26/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,19,-2,11,36,1.545454545,0.472222222,1.727272727,0.527777778,,37,N,N,,,166,NORMAL,17,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,4/23/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.7,4.6,0.1,3.4,5.4,1.382352941,0.87037037,1.352941176,0.851851852,,3.4,N,N,,,215,NORMAL,4.7,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,4/23/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,203,NORMAL,6.84,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,4/23/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,56,11,35,115,1.914285714,0.582608696,1.6,0.486956522,,105.5,N,N,,,199,NORMAL,67,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,4/23/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,43,2.5,0.348837209,2.666666667,0.372093023,,49.5,N,N,,,200,NORMAL,15,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,4/23/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,19,-2,11,36,1.545454545,0.472222222,1.727272727,0.527777778,,37,N,N,,,201,NORMAL,17,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,5/21/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,,245,NORMAL,4.2,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,5/21/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,Y,26.37,N,N,,,233,NORMAL,5.13,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,5/21/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,56,-6,35,115,1.428571429,0.434782609,1.6,0.486956522,,122.5,N,N,,,229,NORMAL,50,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,5/21/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,16,-5,6,43,1.833333333,0.255813953,2.666666667,0.372093023,Y,53.5,N,N,,,230,NORMAL,11,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,5/21/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,19,-3,11,36,1.454545455,0.444444444,1.727272727,0.527777778,,38,N,N,,,231,NORMAL,16,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,6/18/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4.6,-0.5,3.4,5.4,1.205882353,0.759259259,1.352941176,0.851851852,Y,4,N,N,,Y,276,NORMAL,4.1,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,6/18/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4.6,-0.5,3.4,5.4,1.205882353,0.759259259,1.352941176,0.851851852,Y,4,N,N,,Y,276,NORMAL,4.1,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,6/18/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,Y,263,NORMAL,10.26,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,6/18/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,Y,263,NORMAL,10.26,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,6/18/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,54,56,-2,35,115,1.542857143,0.469565217,1.6,0.486956522,,118.5,N,N,,Y,259,NORMAL,54,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,6/18/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,54,56,-2,35,115,1.542857143,0.469565217,1.6,0.486956522,,118.5,N,N,,Y,259,NORMAL,54,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,6/18/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,43,3,0.418604651,2.666666667,0.372093023,,46.5,N,N,,Y,260,NORMAL,18,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,6/18/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,43,3,0.418604651,2.666666667,0.372093023,,46.5,N,N,,Y,260,NORMAL,18,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,6/18/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,19,1,11,36,1.818181818,0.555555556,1.727272727,0.527777778,,34,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,6/18/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,19,1,11,36,1.818181818,0.555555556,1.727272727,0.527777778,,34,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,190,7/9/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,5,4.6,0.4,3.4,5.4,1.470588235,0.925925926,1.352941176,0.851851852,,3.3,N,N,,,311,NORMAL,5,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,190,7/9/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,190,7/9/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,56,-4,35,115,1.485714286,0.452173913,1.6,0.486956522,,120.5,N,N,,,294,NORMAL,52,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,190,7/9/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,43,2.5,0.348837209,2.666666667,0.372093023,,49.5,N,N,,,295,NORMAL,15,0,No
CDISCPILOT01,1097,01-701-1097,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/1/14,7/9/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,190,7/9/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,0,11,36,1.727272727,0.527777778,1.727272727,0.527777778,,35,N,N,,,296,NORMAL,19,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-13,8/25/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-13,8/25/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-13,8/25/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,64,,35,115,1.828571429,0.556521739,1.828571429,0.556521739,,108.5,N,N,Y,,2,NORMAL,64,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-13,8/25/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,,6,32,3.833333333,0.71875,3.833333333,0.71875,,25,N,N,Y,,3,NORMAL,23,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-13,8/25/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,28,,9,34,3.111111111,0.823529412,3.111111111,0.823529412,,23.5,N,N,Y,,4,NORMAL,28,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,11,9/17/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.7,3.9,0.8,3.4,5.4,1.382352941,0.87037037,1.147058824,0.722222222,Y,3.4,N,N,,Y,57,NORMAL,4.7,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,11,9/17/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.7,3.9,0.8,3.4,5.4,1.382352941,0.87037037,1.147058824,0.722222222,Y,3.4,N,N,,Y,57,NORMAL,4.7,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,11,9/17/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,Y,22.95,N,N,,Y,44,NORMAL,8.55,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,11,9/17/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,Y,22.95,N,N,,Y,44,NORMAL,8.55,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,11,9/17/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,64,-6,35,115,1.657142857,0.504347826,1.828571429,0.556521739,Y,114.5,N,N,,Y,39,NORMAL,58,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,11,9/17/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,64,-6,35,115,1.657142857,0.504347826,1.828571429,0.556521739,Y,114.5,N,N,,Y,39,NORMAL,58,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,11,9/17/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,23,-4,6,32,3.166666667,0.59375,3.833333333,0.71875,Y,29,N,N,,Y,40,NORMAL,19,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,11,9/17/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,23,-4,6,32,3.166666667,0.59375,3.833333333,0.71875,Y,29,N,N,,Y,40,NORMAL,19,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,11,9/17/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,28,-5,9,34,2.555555556,0.676470588,3.111111111,0.823529412,Y,28,N,N,,Y,42,NORMAL,23,0,No
CDISCPILOT01,1111,01-701-1111,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/7/12,9/16/12,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,11,9/17/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,28,-5,9,34,2.555555556,0.676470588,3.111111111,0.823529412,Y,28,N,N,,Y,42,NORMAL,23,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-7,11/23/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-7,11/23/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-7,11/23/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,93,,35,115,2.657142857,0.808695652,2.657142857,0.808695652,,79.5,N,N,Y,,2,NORMAL,93,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-7,11/23/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,18,,6,35,3,0.514285714,3,0.514285714,,34.5,N,N,Y,,3,NORMAL,18,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-7,11/23/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,26,,11,36,2.363636364,0.722222222,2.363636364,0.722222222,,28,N,N,Y,,4,NORMAL,26,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,14,12/13/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,5.1,4.3,0.8,3.4,5.4,1.5,0.944444444,1.264705882,0.796296296,,3.4,N,N,,,56,NORMAL,5.1,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,14,12/13/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,14,12/13/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,93,-5,35,115,2.514285714,0.765217391,2.657142857,0.808695652,Y,84.5,N,N,,,39,NORMAL,88,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,14,12/13/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,18,-3,6,35,2.5,0.428571429,3,0.514285714,,37.5,N,N,,,40,NORMAL,15,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,14,12/13/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,26,-1,11,36,2.272727273,0.694444444,2.363636364,0.722222222,,29,N,N,,,41,NORMAL,25,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,12/26/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,4.3,0.4,3.4,5.4,1.382352941,0.87037037,1.264705882,0.796296296,,3.4,N,N,,,90,NORMAL,4.7,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,12/26/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,12/26/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,93,-2,35,115,2.6,0.791304348,2.657142857,0.808695652,,81.5,N,N,,,74,NORMAL,91,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,12/26/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,18,-5,6,35,2.166666667,0.371428571,3,0.514285714,Y,39.5,N,N,,,75,NORMAL,13,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,12/26/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,26,-6,11,36,1.818181818,0.555555556,2.363636364,0.722222222,Y,34,N,N,,,76,NORMAL,20,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, .,,29,12/28/12,UNSCHEDULED 5.1,5.1,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,,107,NORMAL,5.13,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, .,,29,12/28/12,UNSCHEDULED 5.1,5.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,101,93,8,35,115,2.885714286,0.87826087,2.657142857,0.808695652,,83.5,N,N,,,104,NORMAL,101,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, .,,29,12/28/12,UNSCHEDULED 5.1,5.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,18,-2,6,35,2.666666667,0.457142857,3,0.514285714,,36.5,N,N,,,105,NORMAL,16,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, .,,29,12/28/12,UNSCHEDULED 5.1,5.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,26,-3,11,36,2.090909091,0.638888889,2.363636364,0.722222222,,31,N,N,,,106,NORMAL,23,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,42,1/10/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,5.3,4.3,1,3.4,5.4,1.558823529,0.981481481,1.264705882,0.796296296,Y,3.6,N,N,,,135,NORMAL,5.3,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,42,1/10/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,123,NORMAL,6.84,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,42,1/10/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,93,5,35,115,2.8,0.852173913,2.657142857,0.808695652,,80.5,N,N,,,119,NORMAL,98,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,42,1/10/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,18,0,6,35,3,0.514285714,3,0.514285714,,34.5,N,N,,,120,NORMAL,18,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,42,1/10/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,26,-1,11,36,2.272727273,0.694444444,2.363636364,0.722222222,,29,N,N,,,121,NORMAL,25,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,1/23/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.7,4.3,0.4,3.4,5.4,1.382352941,0.87037037,1.264705882,0.796296296,,3.4,N,N,,Y,166,NORMAL,4.7,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,1/23/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.7,4.3,0.4,3.4,5.4,1.382352941,0.87037037,1.264705882,0.796296296,,3.4,N,N,,Y,166,NORMAL,4.7,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,1/23/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,153,NORMAL,8.55,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,1/23/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,153,NORMAL,8.55,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,1/23/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,93,5,35,115,2.8,0.852173913,2.657142857,0.808695652,,80.5,N,N,,Y,149,NORMAL,98,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,1/23/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,93,5,35,115,2.8,0.852173913,2.657142857,0.808695652,,80.5,N,N,,Y,149,NORMAL,98,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,1/23/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,18,-2,6,35,2.666666667,0.457142857,3,0.514285714,,36.5,N,N,,Y,150,NORMAL,16,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,1/23/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,18,-2,6,35,2.666666667,0.457142857,3,0.514285714,,36.5,N,N,,Y,150,NORMAL,16,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,1/23/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,26,-1,11,36,2.272727273,0.694444444,2.363636364,0.722222222,,29,N,N,,Y,151,NORMAL,25,0,No
CDISCPILOT01,1115,01-701-1115,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/30/12,1/23/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,1/23/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,26,-1,11,36,2.272727273,0.694444444,2.363636364,0.722222222,,29,N,N,,Y,151,NORMAL,25,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.7,4.7,,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,Y,,19,NORMAL,4.7,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,65,,31,110,2.096774194,0.590909091,2.096774194,0.590909091,,100,N,N,Y,,2,NORMAL,65,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,,6,43,2.5,0.348837209,2.5,0.348837209,,49.5,N,N,Y,,3,NORMAL,15,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,,11,36,1.363636364,0.416666667,1.363636364,0.416666667,,39,N,N,Y,,4,NORMAL,15,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,,56,NORMAL,4.6,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,Y,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,65,11,31,110,2.451612903,0.690909091,2.096774194,0.590909091,,89,N,N,,,39,NORMAL,76,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,15,-8,6,43,1.166666667,0.162790698,2.5,0.348837209,Y,57.5,N,N,,,40,NORMAL,7,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,11,36,1.181818182,0.361111111,1.363636364,0.416666667,,41,N,N,,,41,NORMAL,13,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,4/9/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,4.7,0,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,,,90,NORMAL,4.7,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,4/9/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,4/9/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,65,2,31,110,2.161290323,0.609090909,2.096774194,0.590909091,,98,N,N,,,74,NORMAL,67,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,4/9/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,0,6,43,2.5,0.348837209,2.5,0.348837209,,49.5,N,N,,,75,NORMAL,15,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,4/9/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,11,36,1.272727273,0.388888889,1.363636364,0.416666667,,40,N,N,,,76,NORMAL,14,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/23/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.8,4.7,0.1,3.4,5.4,1.411764706,0.888888889,1.382352941,0.87037037,,3.3,N,N,,,120,NORMAL,4.8,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/23/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/23/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,65,-3,31,110,2,0.563636364,2.096774194,0.590909091,,103,N,N,,,104,NORMAL,62,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/23/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,15,-4,6,43,1.833333333,0.255813953,2.5,0.348837209,,53.5,N,N,,,105,NORMAL,11,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/23/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,0,11,36,1.363636364,0.416666667,1.363636364,0.416666667,,39,N,N,,,106,NORMAL,15,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 8,8,58,5/8/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.3,4.7,-0.4,3.4,5.4,1.264705882,0.796296296,1.382352941,0.87037037,,3.8,N,N,,,150,NORMAL,4.3,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 8,8,58,5/8/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,138,NORMAL,10.26,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 8,8,58,5/8/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,65,2,31,110,2.161290323,0.609090909,2.096774194,0.590909091,,98,N,N,,,134,NORMAL,67,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 8,8,58,5/8/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,0,6,43,2.5,0.348837209,2.5,0.348837209,,49.5,N,N,,,135,NORMAL,15,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 8,8,58,5/8/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,15,3,11,36,1.636363636,0.5,1.363636364,0.416666667,,36,N,N,,,136,NORMAL,18,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 12,12,86,6/5/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,4.7,-0.5,3.4,5.4,1.235294118,0.777777778,1.382352941,0.87037037,Y,3.9,N,N,,,181,NORMAL,4.2,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 12,12,86,6/5/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,168,NORMAL,8.55,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 12,12,86,6/5/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,65,5,31,110,2.258064516,0.636363636,2.096774194,0.590909091,,95,N,N,,,164,NORMAL,70,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 12,12,86,6/5/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,15,1,6,43,2.666666667,0.372093023,2.5,0.348837209,,48.5,N,N,,,165,NORMAL,16,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 12,12,86,6/5/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,11,36,1.181818182,0.361111111,1.363636364,0.416666667,,41,N,N,,,166,NORMAL,13,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,7/2/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.5,4.7,-0.2,3.4,5.4,1.323529412,0.833333333,1.382352941,0.87037037,,3.6,N,N,,,215,NORMAL,4.5,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,7/2/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,203,NORMAL,10.26,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,7/2/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,65,0,31,110,2.096774194,0.590909091,2.096774194,0.590909091,,100,N,N,,,199,NORMAL,65,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,7/2/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,0,6,43,2.5,0.348837209,2.5,0.348837209,,49.5,N,N,,,200,NORMAL,15,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,7/2/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,15,3,11,36,1.636363636,0.5,1.363636364,0.416666667,,36,N,N,,,201,NORMAL,18,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/30/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.7,-0.5,3.4,5.4,1.235294118,0.777777778,1.382352941,0.87037037,,3.9,N,N,,,245,NORMAL,4.2,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/30/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,233,NORMAL,10.26,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/30/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,65,-3,31,110,2,0.563636364,2.096774194,0.590909091,,103,N,N,,,229,NORMAL,62,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/30/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,43,2.166666667,0.302325581,2.5,0.348837209,,51.5,N,N,,,230,NORMAL,13,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/30/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,11,36,1.272727273,0.388888889,1.363636364,0.416666667,,40,N,N,,,231,NORMAL,14,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 24,24,169,8/27/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,Y,276,NORMAL,4.6,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/27/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,Y,276,NORMAL,4.6,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 24,24,169,8/27/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/27/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 24,24,169,8/27/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,65,-7,31,110,1.870967742,0.527272727,2.096774194,0.590909091,Y,107,N,N,,Y,259,NORMAL,58,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/27/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,65,-7,31,110,1.870967742,0.527272727,2.096774194,0.590909091,Y,107,N,N,,Y,259,NORMAL,58,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 24,24,169,8/27/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,43,2.166666667,0.302325581,2.5,0.348837209,,51.5,N,N,,Y,260,NORMAL,13,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/27/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,43,2.166666667,0.302325581,2.5,0.348837209,,51.5,N,N,,Y,260,NORMAL,13,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 24,24,169,8/27/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,11,15,-4,11,36,1,0.305555556,1.363636364,0.416666667,Y,43,N,N,,Y,261,NORMAL,11,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/27/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,11,15,-4,11,36,1,0.305555556,1.363636364,0.416666667,Y,43,N,N,,Y,261,NORMAL,11,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,9/9/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.1,4.7,-0.6,3.4,5.4,1.205882353,0.759259259,1.382352941,0.87037037,,4,N,N,,,310,NORMAL,4.1,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,9/9/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,9/9/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,65,-9,31,110,1.806451613,0.509090909,2.096774194,0.590909091,,109,N,N,,,294,NORMAL,56,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,9/9/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,15,-5,6,43,1.666666667,0.23255814,2.5,0.348837209,,54.5,N,N,,,295,NORMAL,10,0,No
CDISCPILOT01,1118,01-701-1118,Placebo,0,Placebo,0,3/12/14,9/9/14,52,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,9/9/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,12,15,-3,11,36,1.090909091,0.333333333,1.363636364,0.416666667,,42,N,N,,,296,NORMAL,12,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-6,2/9/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.2,4.2,,3.4,5.4,1.235294118,0.777777778,1.235294118,0.777777778,,3.9,N,N,Y,,19,NORMAL,4.2,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-6,2/9/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-6,2/9/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,Y,,2,NORMAL,61,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-6,2/9/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,,6,35,2.5,0.428571429,2.5,0.428571429,,37.5,N,N,Y,,3,NORMAL,15,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-6,2/9/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,Y,,4,NORMAL,24,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,3/1/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.5,4.2,0.3,3.4,5.4,1.323529412,0.833333333,1.235294118,0.777777778,,3.6,N,N,,,56,NORMAL,4.5,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,3/1/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,3/1/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,0,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,,,39,NORMAL,61,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,3/1/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,15,-1,6,35,2.333333333,0.4,2.5,0.428571429,,38.5,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,3/1/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,24,2,11,36,2.363636364,0.722222222,2.181818182,0.666666667,,28,N,N,,,41,NORMAL,26,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 4,4,29,3/15/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.2,0.4,3.4,5.4,1.352941176,0.851851852,1.235294118,0.777777778,,3.5,N,N,,,90,NORMAL,4.6,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 4,4,29,3/15/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,Y,26.37,N,N,,,78,NORMAL,5.13,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 4,4,29,3/15/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,61,7,35,115,1.942857143,0.591304348,1.742857143,0.530434783,,104.5,N,N,,,74,NORMAL,68,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 4,4,29,3/15/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,15,3,6,35,3,0.514285714,2.5,0.428571429,,34.5,N,N,,,75,NORMAL,18,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 4,4,29,3/15/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,24,1,11,36,2.272727273,0.694444444,2.181818182,0.666666667,,29,N,N,,,76,NORMAL,25,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,3/29/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.2,0.1,3.4,5.4,1.264705882,0.796296296,1.235294118,0.777777778,,3.8,N,N,,,120,NORMAL,4.3,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,3/29/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,108,NORMAL,6.84,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,3/29/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,61,2,35,115,1.8,0.547826087,1.742857143,0.530434783,,109.5,N,N,,,104,NORMAL,63,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,3/29/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,35,2.166666667,0.371428571,2.5,0.428571429,,39.5,N,N,,,105,NORMAL,13,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,3/29/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,24,-5,11,36,1.727272727,0.527777778,2.181818182,0.666666667,,35,N,N,,,106,NORMAL,19,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 8,8,57,4/12/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,4.2,0.3,3.4,5.4,1.323529412,0.833333333,1.235294118,0.777777778,,3.6,N,N,,,150,NORMAL,4.5,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 8,8,57,4/12/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,138,NORMAL,10.26,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 8,8,57,4/12/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,61,-3,35,115,1.657142857,0.504347826,1.742857143,0.530434783,Y,114.5,N,N,,,134,NORMAL,58,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 8,8,57,4/12/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,15,-5,6,35,1.666666667,0.285714286,2.5,0.428571429,Y,42.5,N,N,,,135,NORMAL,10,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 8,8,57,4/12/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,24,-6,11,36,1.636363636,0.5,2.181818182,0.666666667,Y,36,N,N,,,136,NORMAL,18,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 12,12,91,5/16/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.2,0.2,3.4,5.4,1.294117647,0.814814815,1.235294118,0.777777778,,3.7,N,N,,,181,NORMAL,4.4,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 12,12,91,5/16/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,168,NORMAL,8.55,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 12,12,91,5/16/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,61,2,35,115,1.8,0.547826087,1.742857143,0.530434783,,109.5,N,N,,,164,NORMAL,63,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 12,12,91,5/16/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,35,2.166666667,0.371428571,2.5,0.428571429,,39.5,N,N,,,165,NORMAL,13,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 12,12,91,5/16/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,24,-3,11,36,1.909090909,0.583333333,2.181818182,0.666666667,,33,N,N,,,166,NORMAL,21,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 16,16,113,6/7/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,4.2,-0.2,3.4,5.4,1.176470588,0.740740741,1.235294118,0.777777778,Y,4.1,N,N,,,215,NORMAL,4,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 16,16,113,6/7/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,203,NORMAL,10.26,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 16,16,113,6/7/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,61,4,35,115,1.857142857,0.565217391,1.742857143,0.530434783,,107.5,N,N,,,199,NORMAL,65,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 16,16,113,6/7/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,15,-3,6,35,2,0.342857143,2.5,0.428571429,,40.5,N,N,,,200,NORMAL,12,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 16,16,113,6/7/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,24,-5,11,36,1.727272727,0.527777778,2.181818182,0.666666667,,35,N,N,,,201,NORMAL,19,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 20,20,138,7/2/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4,4.2,-0.2,3.4,5.4,1.176470588,0.740740741,1.235294118,0.777777778,,4.1,N,N,,,245,NORMAL,4,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 20,20,138,7/2/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,233,NORMAL,6.84,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 20,20,138,7/2/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,61,1,35,115,1.771428571,0.539130435,1.742857143,0.530434783,,110.5,N,N,,,229,NORMAL,62,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 20,20,138,7/2/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,15,-4,6,35,1.833333333,0.314285714,2.5,0.428571429,,41.5,N,N,,,230,NORMAL,11,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 20,20,138,7/2/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,24,-5,11,36,1.727272727,0.527777778,2.181818182,0.666666667,,35,N,N,,,231,NORMAL,19,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,8/2/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.3,4.2,0.1,3.4,5.4,1.264705882,0.796296296,1.235294118,0.777777778,,3.8,N,N,,Y,276,NORMAL,4.3,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/2/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.3,4.2,0.1,3.4,5.4,1.264705882,0.796296296,1.235294118,0.777777778,,3.8,N,N,,Y,276,NORMAL,4.3,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,8/2/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,Y,263,NORMAL,11.97,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/2/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,Y,263,NORMAL,11.97,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,8/2/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,61,4,35,115,1.857142857,0.565217391,1.742857143,0.530434783,,107.5,N,N,,Y,259,NORMAL,65,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/2/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,61,4,35,115,1.857142857,0.565217391,1.742857143,0.530434783,,107.5,N,N,,Y,259,NORMAL,65,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,8/2/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,35,2.166666667,0.371428571,2.5,0.428571429,,39.5,N,N,,Y,260,NORMAL,13,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/2/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,35,2.166666667,0.371428571,2.5,0.428571429,,39.5,N,N,,Y,260,NORMAL,13,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,8/2/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,11,36,2,0.611111111,2.181818182,0.666666667,,32,N,N,,Y,261,NORMAL,22,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,8/2/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,11,36,2,0.611111111,2.181818182,0.666666667,,32,N,N,,Y,261,NORMAL,22,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,8/16/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.2,4.2,0,3.4,5.4,1.235294118,0.777777778,1.235294118,0.777777778,,3.9,N,N,,,310,NORMAL,4.2,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,8/16/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,298,NORMAL,10.26,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,8/16/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,61,6,35,115,1.914285714,0.582608696,1.742857143,0.530434783,,105.5,N,N,,,294,NORMAL,67,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,8/16/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,15,-5,6,35,1.666666667,0.285714286,2.5,0.428571429,,42.5,N,N,,,295,NORMAL,10,0,No
CDISCPILOT01,1130,01-701-1130,Placebo,0,Placebo,0,2/15/14,8/16/14,84,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,8/16/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,24,-5,11,36,1.727272727,0.527777778,2.181818182,0.666666667,,35,N,N,,,296,NORMAL,19,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-5,10/23/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.4,4.4,,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,Y,,19,NORMAL,4.4,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-5,10/23/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,15.39,15.39,,3,21,5.13,0.732857143,5.13,0.732857143,,16.11,N,N,Y,,6,NORMAL,15.39,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-5,10/23/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,59,,35,115,1.685714286,0.513043478,1.685714286,0.513043478,,113.5,N,N,Y,,2,NORMAL,59,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-5,10/23/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,,6,32,3.833333333,0.71875,3.833333333,0.71875,,25,N,N,Y,,3,NORMAL,23,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-5,10/23/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,27,,9,34,3,0.794117647,3,0.794117647,,24,N,N,Y,,4,NORMAL,27,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,30,11/26/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.5,4.4,0.1,3.4,5.4,1.323529412,0.833333333,1.294117647,0.814814815,,3.6,N,N,,,72,NORMAL,4.5,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,30,11/26/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,15.39,-5.13,3,21,3.42,0.488571429,5.13,0.732857143,Y,21.24,N,N,,,60,NORMAL,10.26,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,30,11/26/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,59,4,35,115,1.8,0.547826087,1.685714286,0.513043478,,109.5,N,N,,,56,NORMAL,63,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,30,11/26/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,23,-2,6,32,3.5,0.65625,3.833333333,0.71875,,27,N,N,,,57,NORMAL,21,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,30,11/26/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,27,-7,9,34,2.222222222,0.588235294,3,0.794117647,,31,N,N,,,58,NORMAL,20,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,45,12/11/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,102,NORMAL,4.4,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,45,12/11/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,11.97,15.39,-3.42,3,21,3.99,0.57,5.13,0.732857143,,19.53,N,N,,,90,NORMAL,11.97,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,45,12/11/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,59,2,35,115,1.742857143,0.530434783,1.685714286,0.513043478,,111.5,N,N,,,86,NORMAL,61,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,45,12/11/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,23,-8,6,32,2.5,0.46875,3.833333333,0.71875,Y,33,N,N,,,87,NORMAL,15,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,45,12/11/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,27,-7,9,34,2.222222222,0.588235294,3,0.794117647,,31,N,N,,,88,NORMAL,20,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,58,12/24/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,132,NORMAL,4.4,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,58,12/24/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,15.39,-5.13,3,21,3.42,0.488571429,5.13,0.732857143,,21.24,N,N,,,120,NORMAL,10.26,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,58,12/24/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,59,1,35,115,1.714285714,0.52173913,1.685714286,0.513043478,,112.5,N,N,,,116,NORMAL,60,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,58,12/24/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,23,-7,6,32,2.666666667,0.5,3.833333333,0.71875,,32,N,N,,,117,NORMAL,16,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,58,12/24/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,27,-8,9,34,2.111111111,0.558823529,3,0.794117647,Y,32,N,N,,,118,NORMAL,19,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,87,1/22/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,4.4,-0.5,3.4,5.4,1.147058824,0.722222222,1.294117647,0.814814815,Y,4.2,N,N,,,163,NORMAL,3.9,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,87,1/22/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,15.39,-5.13,3,21,3.42,0.488571429,5.13,0.732857143,,21.24,N,N,,,150,NORMAL,10.26,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,87,1/22/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,59,9,35,115,1.942857143,0.591304348,1.685714286,0.513043478,,104.5,N,N,,,146,NORMAL,68,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,87,1/22/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,23,-7,6,32,2.666666667,0.5,3.833333333,0.71875,,32,N,N,,,147,NORMAL,16,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,87,1/22/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,27,-8,9,34,2.111111111,0.558823529,3,0.794117647,,32,N,N,,,148,NORMAL,19,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,114,2/18/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.8,4.4,0.4,3.4,5.4,1.411764706,0.888888889,1.294117647,0.814814815,,3.3,N,N,,,197,NORMAL,4.8,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,114,2/18/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,13.68,15.39,-1.71,3,21,4.56,0.651428571,5.13,0.732857143,,17.82,N,N,,,185,NORMAL,13.68,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,114,2/18/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,59,-2,35,115,1.628571429,0.495652174,1.685714286,0.513043478,,115.5,N,N,,,181,NORMAL,57,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,114,2/18/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,23,-8,6,32,2.5,0.46875,3.833333333,0.71875,,33,N,N,,,182,NORMAL,15,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,114,2/18/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,27,-8,9,34,2.111111111,0.558823529,3,0.794117647,,32,N,N,,,183,NORMAL,19,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,142,3/18/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.9,4.4,-0.5,3.4,5.4,1.147058824,0.722222222,1.294117647,0.814814815,,4.2,N,N,,,227,NORMAL,3.9,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,142,3/18/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,10.26,15.39,-5.13,3,21,3.42,0.488571429,5.13,0.732857143,,21.24,N,N,,,215,NORMAL,10.26,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,142,3/18/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,59,4,35,115,1.8,0.547826087,1.685714286,0.513043478,,109.5,N,N,,,211,NORMAL,63,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,142,3/18/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,23,-4,6,32,3.166666667,0.59375,3.833333333,0.71875,,29,N,N,,,212,NORMAL,19,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,142,3/18/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,27,-6,9,34,2.333333333,0.617647059,3,0.794117647,,30,N,N,,,213,NORMAL,21,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,173,4/18/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,4.4,-0.5,3.4,5.4,1.147058824,0.722222222,1.294117647,0.814814815,,4.2,N,N,,Y,258,NORMAL,3.9,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,173,4/18/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,4.4,-0.5,3.4,5.4,1.147058824,0.722222222,1.294117647,0.814814815,,4.2,N,N,,Y,258,NORMAL,3.9,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,173,4/18/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,15.39,-3.42,3,21,3.99,0.57,5.13,0.732857143,,19.53,N,N,,Y,245,NORMAL,11.97,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,173,4/18/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,15.39,-3.42,3,21,3.99,0.57,5.13,0.732857143,,19.53,N,N,,Y,245,NORMAL,11.97,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,173,4/18/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,59,-3,35,115,1.6,0.486956522,1.685714286,0.513043478,Y,116.5,N,N,,Y,241,NORMAL,56,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,173,4/18/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,59,-3,35,115,1.6,0.486956522,1.685714286,0.513043478,Y,116.5,N,N,,Y,241,NORMAL,56,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,173,4/18/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,23,-5,6,32,3,0.5625,3.833333333,0.71875,,30,N,N,,Y,242,NORMAL,18,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,173,4/18/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,23,-5,6,32,3,0.5625,3.833333333,0.71875,,30,N,N,,Y,242,NORMAL,18,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,173,4/18/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,27,-4,9,34,2.555555556,0.676470588,3,0.794117647,,28,N,N,,Y,243,NORMAL,23,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,173,4/18/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,27,-4,9,34,2.555555556,0.676470588,3,0.794117647,,28,N,N,,Y,243,NORMAL,23,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,184,4/29/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.8,4.4,0.4,3.4,5.4,1.411764706,0.888888889,1.294117647,0.814814815,,3.3,N,N,,,292,NORMAL,4.8,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,184,4/29/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,11.97,15.39,-3.42,3,21,3.99,0.57,5.13,0.732857143,,19.53,N,N,,,280,NORMAL,11.97,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,184,4/29/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,59,-1,35,115,1.657142857,0.504347826,1.685714286,0.513043478,,114.5,N,N,,,276,NORMAL,58,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,184,4/29/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,23,-6,6,32,2.833333333,0.53125,3.833333333,0.71875,,31,N,N,,,277,NORMAL,17,0,No
CDISCPILOT01,1133,01-701-1133,Xanomeline High Dose,81,Xanomeline High Dose,81,10/28/12,4/28/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,184,4/29/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,27,-7,9,34,2.222222222,0.588235294,3,0.794117647,,31,N,N,,,278,NORMAL,20,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-13,5/7/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-13,5/7/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,Y,,6,NORMAL,5.13,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-13,5/7/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,33,33,,35,115,0.942857143,0.286956522,0.942857143,0.286956522,,139.5,N,N,Y,,2,LOW,33,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-13,5/7/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,,6,32,2.5,0.46875,2.5,0.46875,,33,N,N,Y,,3,NORMAL,15,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-13,5/7/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,14,,9,34,1.555555556,0.411764706,1.555555556,0.411764706,,37,N,N,Y,,4,NORMAL,14,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,15,6/3/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,56,NORMAL,4.3,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,15,6/3/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,15,6/3/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,35,33,2,35,115,1,0.304347826,0.942857143,0.286956522,,137.5,N,N,,,39,NORMAL,35,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,15,6/3/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,15,-1,6,32,2.333333333,0.4375,2.5,0.46875,,34,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,15,6/3/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,14,6,9,34,2.222222222,0.588235294,1.555555556,0.411764706,,31,N,N,,,41,NORMAL,20,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,6/16/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.3,0.3,3.4,5.4,1.352941176,0.851851852,1.264705882,0.796296296,,3.5,N,N,,,90,NORMAL,4.6,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,6/16/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,Y,26.37,N,N,,,78,NORMAL,5.13,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,6/16/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,34,33,1,35,115,0.971428571,0.295652174,0.942857143,0.286956522,,138.5,N,N,,,74,LOW,34,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,6/16/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,15,1,6,32,2.666666667,0.5,2.5,0.46875,,32,N,N,,,75,NORMAL,16,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,6/16/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,14,5,9,34,2.111111111,0.558823529,1.555555556,0.411764706,Y,32,N,N,,,76,NORMAL,19,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,42,6/30/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,Y,3.9,N,N,,Y,121,NORMAL,4.2,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,42,6/30/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,Y,3.9,N,N,,Y,121,NORMAL,4.2,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,42,6/30/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,5.13,5.13,3,21,3.42,0.488571429,1.71,0.244285714,,21.24,N,N,,Y,108,NORMAL,10.26,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,42,6/30/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,5.13,5.13,3,21,3.42,0.488571429,1.71,0.244285714,,21.24,N,N,,Y,108,NORMAL,10.26,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,42,6/30/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,29,33,-4,35,115,0.828571429,0.252173913,0.942857143,0.286956522,Y,143.5,N,N,,Y,104,LOW,29,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,42,6/30/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,29,33,-4,35,115,0.828571429,0.252173913,0.942857143,0.286956522,Y,143.5,N,N,,Y,104,LOW,29,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,42,6/30/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,32,2.166666667,0.40625,2.5,0.46875,Y,35,N,N,,Y,105,NORMAL,13,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,42,6/30/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,32,2.166666667,0.40625,2.5,0.46875,Y,35,N,N,,Y,105,NORMAL,13,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,42,6/30/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,14,6,9,34,2.222222222,0.588235294,1.555555556,0.411764706,,31,N,N,,Y,106,NORMAL,20,0,No
CDISCPILOT01,1146,01-701-1146,Xanomeline High Dose,81,Xanomeline High Dose,81,5/20/13,6/26/13,75,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,42,6/30/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,14,6,9,34,2.222222222,0.588235294,1.555555556,0.411764706,,31,N,N,,Y,106,NORMAL,20,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-9,8/14/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-9,8/14/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-9,8/14/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,88,,31,110,2.838709677,0.8,2.838709677,0.8,,77,N,N,Y,,2,NORMAL,88,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-9,8/14/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,34,34,,6,43,5.666666667,0.790697674,5.666666667,0.790697674,,31,N,N,Y,,3,NORMAL,34,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-9,8/14/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,11,36,2.272727273,0.694444444,2.272727273,0.694444444,,29,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 2,2,14,9/5/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.9,4,-0.1,3.4,5.4,1.147058824,0.722222222,1.176470588,0.740740741,,4.2,N,N,,,56,NORMAL,3.9,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 2,2,14,9/5/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 2,2,14,9/5/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,88,-5,31,110,2.677419355,0.754545455,2.838709677,0.8,,82,N,N,,,39,NORMAL,83,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 2,2,14,9/5/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,41,34,7,6,43,6.833333333,0.953488372,5.666666667,0.790697674,Y,38,N,N,,,40,NORMAL,41,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 2,2,14,9/5/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,25,2,11,36,2.454545455,0.75,2.272727273,0.694444444,,27,N,N,,,41,NORMAL,27,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 4,4,28,9/19/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.4,4,-0.6,3.4,5.4,1,0.62962963,1.176470588,0.740740741,Y,4.7,N,N,,,90,NORMAL,3.4,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 4,4,28,9/19/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 4,4,28,9/19/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,82,88,-6,31,110,2.64516129,0.745454545,2.838709677,0.8,,83,N,N,,,74,NORMAL,82,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 4,4,28,9/19/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,35,34,1,6,43,5.833333333,0.813953488,5.666666667,0.790697674,,32,N,N,,,75,NORMAL,35,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 4,4,28,9/19/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,0,11,36,2.272727273,0.694444444,2.272727273,0.694444444,,29,N,N,,,76,NORMAL,25,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 6,6,42,10/3/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.8,4,-0.2,3.4,5.4,1.117647059,0.703703704,1.176470588,0.740740741,,4.3,N,N,,,120,NORMAL,3.8,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 6,6,42,10/3/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 6,6,42,10/3/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,88,-12,31,110,2.451612903,0.690909091,2.838709677,0.8,Y,89,N,N,,,104,NORMAL,76,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 6,6,42,10/3/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,31,34,-3,6,43,5.166666667,0.720930233,5.666666667,0.790697674,,33.5,N,N,,,105,NORMAL,31,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 6,6,42,10/3/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,25,-3,11,36,2,0.611111111,2.272727273,0.694444444,Y,32,N,N,,,106,NORMAL,22,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,10/18/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.5,4,-0.5,3.4,5.4,1.029411765,0.648148148,1.176470588,0.740740741,,4.6,N,N,,,150,NORMAL,3.5,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,10/18/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,10/18/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,88,-8,31,110,2.580645161,0.727272727,2.838709677,0.8,,85,N,N,,,134,NORMAL,80,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,10/18/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,31,34,-3,6,43,5.166666667,0.720930233,5.666666667,0.790697674,,33.5,N,N,,,135,NORMAL,31,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,10/18/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,25,1,11,36,2.363636364,0.722222222,2.272727273,0.694444444,,28,N,N,,,136,NORMAL,26,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 12,12,87,11/17/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,,181,NORMAL,4,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 12,12,87,11/17/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,168,NORMAL,6.84,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 12,12,87,11/17/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,88,-7,31,110,2.612903226,0.736363636,2.838709677,0.8,,84,N,N,,,164,NORMAL,81,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 12,12,87,11/17/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,39,34,5,6,43,6.5,0.906976744,5.666666667,0.790697674,,36,N,N,,,165,NORMAL,39,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 12,12,87,11/17/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,0,11,36,2.272727273,0.694444444,2.272727273,0.694444444,,29,N,N,,,166,NORMAL,25,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,12/13/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,3.7,4,-0.3,3.4,5.4,1.088235294,0.685185185,1.176470588,0.740740741,,4.4,N,N,,,215,NORMAL,3.7,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,12/13/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,,203,NORMAL,11.97,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,12/13/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,85,88,-3,31,110,2.741935484,0.772727273,2.838709677,0.8,,80,N,N,,,199,NORMAL,85,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,12/13/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,34,-1,6,43,5.5,0.76744186,5.666666667,0.790697674,,31.5,N,N,,,200,NORMAL,33,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,12/13/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,25,1,11,36,2.363636364,0.722222222,2.272727273,0.694444444,,28,N,N,,,201,NORMAL,26,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,1/10/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,,245,NORMAL,4,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,1/10/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,233,NORMAL,6.84,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,1/10/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,88,-4,31,110,2.709677419,0.763636364,2.838709677,0.8,,81,N,N,,,229,NORMAL,84,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,1/10/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,32,34,-2,6,43,5.333333333,0.744186047,5.666666667,0.790697674,,32.5,N,N,,,230,NORMAL,32,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,1/10/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,25,1,11,36,2.363636364,0.722222222,2.272727273,0.694444444,,28,N,N,,,231,NORMAL,26,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 24,24,170,2/8/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,4,-0.2,3.4,5.4,1.117647059,0.703703704,1.176470588,0.740740741,,4.3,N,N,,Y,276,NORMAL,3.8,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,170,2/8/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,4,-0.2,3.4,5.4,1.117647059,0.703703704,1.176470588,0.740740741,,4.3,N,N,,Y,276,NORMAL,3.8,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 24,24,170,2/8/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,Y,263,NORMAL,6.84,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,170,2/8/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,Y,263,NORMAL,6.84,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 24,24,170,2/8/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,88,-9,31,110,2.548387097,0.718181818,2.838709677,0.8,,86,N,N,,Y,259,NORMAL,79,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,170,2/8/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,88,-9,31,110,2.548387097,0.718181818,2.838709677,0.8,,86,N,N,,Y,259,NORMAL,79,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 24,24,170,2/8/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,37,34,3,6,43,6.166666667,0.860465116,5.666666667,0.790697674,,34,N,N,,Y,260,NORMAL,37,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,170,2/8/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,37,34,3,6,43,6.166666667,0.860465116,5.666666667,0.790697674,,34,N,N,,Y,260,NORMAL,37,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 24,24,170,2/8/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,11,36,2.727272727,0.833333333,2.272727273,0.694444444,,24.5,N,N,,Y,261,NORMAL,30,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,170,2/8/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,11,36,2.727272727,0.833333333,2.272727273,0.694444444,,24.5,N,N,,Y,261,NORMAL,30,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,2/20/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,3.7,4,-0.3,3.4,5.4,1.088235294,0.685185185,1.176470588,0.740740741,,4.4,N,N,,,310,NORMAL,3.7,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,2/20/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,298,NORMAL,6.84,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,2/20/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,88,-10,31,110,2.516129032,0.709090909,2.838709677,0.8,,87,N,N,,,294,NORMAL,78,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,2/20/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,28,34,-6,6,43,4.666666667,0.651162791,5.666666667,0.790697674,,36.5,N,N,,,295,NORMAL,28,0,No
CDISCPILOT01,1148,01-701-1148,Xanomeline High Dose,81,Xanomeline High Dose,81,8/23/13,2/20/14,57,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,2/20/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,25,-2,11,36,2.090909091,0.638888889,2.272727273,0.694444444,,31,N,N,,,296,NORMAL,23,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-17,9/6/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.7,3.7,,3.4,5.4,1.088235294,0.685185185,1.088235294,0.685185185,,4.4,N,N,Y,,19,NORMAL,3.7,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-17,9/6/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,Y,,6,NORMAL,5.13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-17,9/6/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,65,,35,115,1.857142857,0.565217391,1.857142857,0.565217391,,107.5,N,N,Y,,2,NORMAL,65,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-17,9/6/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,Y,,3,NORMAL,13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-17,9/6/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,,9,34,2.666666667,0.705882353,2.666666667,0.705882353,,27,N,N,Y,,4,NORMAL,24,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/8/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,3.7,0.3,3.4,5.4,1.176470588,0.740740741,1.088235294,0.685185185,,4.1,N,N,,,56,NORMAL,4,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/8/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/8/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,65,-1,35,115,1.828571429,0.556521739,1.857142857,0.565217391,,108.5,N,N,,,39,NORMAL,64,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/8/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/8/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,24,1,9,34,2.777777778,0.735294118,2.666666667,0.705882353,,26,N,N,,,41,NORMAL,25,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,10/19/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,3.7,0.2,3.4,5.4,1.147058824,0.722222222,1.088235294,0.685185185,,4.2,N,N,,,90,NORMAL,3.9,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,10/19/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,10/19/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,65,-7,35,115,1.657142857,0.504347826,1.857142857,0.565217391,,114.5,N,N,,,74,NORMAL,58,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,10/19/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,75,NORMAL,14,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,10/19/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,9,34,2.444444444,0.647058824,2.666666667,0.705882353,,29,N,N,,,76,NORMAL,22,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4,3.7,0.3,3.4,5.4,1.176470588,0.740740741,1.088235294,0.685185185,,4.1,N,N,,,125,NORMAL,4,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,113,NORMAL,6.84,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,54,65,-11,35,115,1.542857143,0.469565217,1.857142857,0.565217391,,118.5,N,N,,,109,NORMAL,54,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,110,NORMAL,14,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,9,34,2.444444444,0.647058824,2.666666667,0.705882353,,29,N,N,,,111,NORMAL,22,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,11/18/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.9,3.7,0.2,3.4,5.4,1.147058824,0.722222222,1.088235294,0.685185185,,4.2,N,N,,,155,NORMAL,3.9,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,11/18/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,Y,26.37,N,N,,,143,NORMAL,5.13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,11/18/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,65,-5,35,115,1.714285714,0.52173913,1.857142857,0.565217391,,112.5,N,N,,,139,NORMAL,60,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,11/18/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,13,-2,6,32,1.833333333,0.34375,2.166666667,0.40625,Y,37,N,N,,,140,NORMAL,11,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,57,11/18/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,24,-3,9,34,2.333333333,0.617647059,2.666666667,0.705882353,Y,30,N,N,,,141,NORMAL,21,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,12/16/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,3.7,0.2,3.4,5.4,1.147058824,0.722222222,1.088235294,0.685185185,,4.2,N,N,,,186,NORMAL,3.9,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,12/16/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,173,NORMAL,6.84,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,12/16/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,65,-8,35,115,1.628571429,0.495652174,1.857142857,0.565217391,,115.5,N,N,,,169,NORMAL,57,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,12/16/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,,,170,NORMAL,13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,12/16/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,9,34,2.444444444,0.647058824,2.666666667,0.705882353,,29,N,N,,,171,NORMAL,22,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,108,1/8/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,3.7,3.7,0,3.4,5.4,1.088235294,0.685185185,1.088235294,0.685185185,Y,4.4,N,N,,,230,NORMAL,3.7,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,108,1/8/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,,218,NORMAL,8.55,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,108,1/8/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,65,-12,35,115,1.514285714,0.460869565,1.857142857,0.565217391,Y,119.5,N,N,,,214,NORMAL,53,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,108,1/8/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,13,4,6,32,2.833333333,0.53125,2.166666667,0.40625,,31,N,N,,,215,NORMAL,17,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,108,1/8/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,24,1,9,34,2.777777778,0.735294118,2.666666667,0.705882353,,26,N,N,,,216,NORMAL,25,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,2/11/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.9,3.7,0.2,3.4,5.4,1.147058824,0.722222222,1.088235294,0.685185185,,4.2,N,N,,,260,NORMAL,3.9,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,2/11/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,,248,NORMAL,5.13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,2/11/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,65,-5,35,115,1.714285714,0.52173913,1.857142857,0.565217391,,112.5,N,N,,,244,NORMAL,60,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,2/11/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,245,NORMAL,14,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,2/11/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,0,9,34,2.666666667,0.705882353,2.666666667,0.705882353,,27,N,N,,,246,NORMAL,24,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,3/11/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,3.7,0.1,3.4,5.4,1.117647059,0.703703704,1.088235294,0.685185185,,4.3,N,N,,Y,291,NORMAL,3.8,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,3/11/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,3.7,0.1,3.4,5.4,1.117647059,0.703703704,1.088235294,0.685185185,,4.3,N,N,,Y,291,NORMAL,3.8,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,3/11/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,Y,278,NORMAL,6.84,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,3/11/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,Y,278,NORMAL,6.84,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,3/11/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,65,-2,35,115,1.8,0.547826087,1.857142857,0.565217391,,109.5,N,N,,Y,274,NORMAL,63,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,3/11/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,65,-2,35,115,1.8,0.547826087,1.857142857,0.565217391,,109.5,N,N,,Y,274,NORMAL,63,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,3/11/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,,Y,275,NORMAL,13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,3/11/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,,Y,275,NORMAL,13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,3/11/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,9,34,2.444444444,0.647058824,2.666666667,0.705882353,,29,N,N,,Y,276,NORMAL,22,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,3/11/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,24,-2,9,34,2.444444444,0.647058824,2.666666667,0.705882353,,29,N,N,,Y,276,NORMAL,22,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,191,4/1/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,3.6,3.7,-0.1,3.4,5.4,1.058823529,0.666666667,1.088235294,0.685185185,,4.5,N,N,,,325,NORMAL,3.6,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,191,4/1/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,,313,NORMAL,5.13,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,191,4/1/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,65,-8,35,115,1.628571429,0.495652174,1.857142857,0.565217391,,115.5,N,N,,,309,NORMAL,57,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,191,4/1/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,310,NORMAL,14,0,No
CDISCPILOT01,1153,01-701-1153,Placebo,0,Placebo,0,9/23/13,3/16/14,79,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,191,4/1/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,9,34,2.555555556,0.676470588,2.666666667,0.705882353,,28,N,N,,,311,NORMAL,23,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-15,1/28/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-15,1/28/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-15,1/28/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,77,,31,110,2.483870968,0.7,2.483870968,0.7,,88,N,N,Y,,2,NORMAL,77,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-15,1/28/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,29,,6,43,4.833333333,0.674418605,4.833333333,0.674418605,,35.5,N,N,Y,,3,NORMAL,29,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-15,1/28/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,Y,,4,NORMAL,21,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.5,4.5,0,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,,,56,NORMAL,4.5,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,Y,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,77,2,31,110,2.548387097,0.718181818,2.483870968,0.7,,86,N,N,,,39,NORMAL,79,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,29,0,6,43,4.833333333,0.674418605,4.833333333,0.674418605,,35.5,N,N,,,40,NORMAL,29,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,2/25/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,21,4,11,36,2.272727273,0.694444444,1.909090909,0.583333333,,29,N,N,,,41,NORMAL,25,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,28,3/11/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.4,4.5,-0.1,3.4,5.4,1.294117647,0.814814815,1.323529412,0.833333333,,3.7,N,N,,,90,NORMAL,4.4,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,28,3/11/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,28,3/11/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,77,-11,31,110,2.129032258,0.6,2.483870968,0.7,Y,99,N,N,,,74,NORMAL,66,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,28,3/11/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,29,-9,6,43,3.333333333,0.465116279,4.833333333,0.674418605,,44.5,N,N,,,75,NORMAL,20,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,28,3/11/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,21,-4,11,36,1.545454545,0.472222222,1.909090909,0.583333333,Y,37,N,N,,,76,NORMAL,17,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,3/23/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,Y,3.8,N,N,,Y,121,NORMAL,4.3,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,3/23/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,Y,3.8,N,N,,Y,121,NORMAL,4.3,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,3/23/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,108,NORMAL,8.55,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,3/23/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,108,NORMAL,8.55,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,3/23/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,77,-8,31,110,2.225806452,0.627272727,2.483870968,0.7,,96,N,N,,Y,104,NORMAL,69,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,3/23/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,77,-8,31,110,2.225806452,0.627272727,2.483870968,0.7,,96,N,N,,Y,104,NORMAL,69,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,3/23/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,29,-10,6,43,3.166666667,0.441860465,4.833333333,0.674418605,Y,45.5,N,N,,Y,105,NORMAL,19,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,3/23/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,29,-10,6,43,3.166666667,0.441860465,4.833333333,0.674418605,Y,45.5,N,N,,Y,105,NORMAL,19,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,3/23/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,0,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,,Y,106,NORMAL,21,0,No
CDISCPILOT01,1180,01-701-1180,Xanomeline High Dose,81,Xanomeline High Dose,81,2/12/13,3/18/13,56,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,3/23/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,0,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,,Y,106,NORMAL,21,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-9,11/26/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-9,11/26/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,Y,,6,NORMAL,5.13,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-9,11/26/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,79,,35,115,2.257142857,0.686956522,2.257142857,0.686956522,,93.5,N,N,Y,,2,NORMAL,79,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-9,11/26/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,18,,6,32,3,0.5625,3,0.5625,,30,N,N,Y,,3,NORMAL,18,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-9,11/26/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,8,12/12/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4.1,0.1,3.4,5.4,1.235294118,0.777777778,1.205882353,0.759259259,Y,3.9,N,N,,Y,56,NORMAL,4.2,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,8,12/12/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4.1,0.1,3.4,5.4,1.235294118,0.777777778,1.205882353,0.759259259,Y,3.9,N,N,,Y,56,NORMAL,4.2,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,8,12/12/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,Y,22.95,N,N,,Y,43,NORMAL,8.55,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,8,12/12/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,Y,22.95,N,N,,Y,43,NORMAL,8.55,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,8,12/12/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,79,26,35,115,3,0.913043478,2.257142857,0.686956522,Y,87.5,N,N,,Y,39,NORMAL,105,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,8,12/12/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,79,26,35,115,3,0.913043478,2.257142857,0.686956522,Y,87.5,N,N,,Y,39,NORMAL,105,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,8,12/12/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,18,-4,6,32,2.333333333,0.4375,3,0.5625,Y,34,N,N,,Y,40,NORMAL,14,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,8,12/12/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,18,-4,6,32,2.333333333,0.4375,3,0.5625,Y,34,N,N,,Y,40,NORMAL,14,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,8,12/12/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,Y,28,N,N,,Y,41,NORMAL,23,0,No
CDISCPILOT01,1181,01-701-1181,Xanomeline High Dose,81,Xanomeline High Dose,81,12/5/13,12/9/13,79,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,8,12/12/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,Y,28,N,N,,Y,41,NORMAL,23,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-12,2/3/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.7,4.7,,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,Y,,19,NORMAL,4.7,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-12,2/3/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-12,2/3/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,99,99,,35,115,2.828571429,0.860869565,2.828571429,0.860869565,,81.5,N,N,Y,,2,NORMAL,99,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-12,2/3/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,,6,35,3.5,0.6,3.5,0.6,,31.5,N,N,Y,,3,NORMAL,21,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-12,2/3/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,Y,,4,NORMAL,17,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/2/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.5,4.7,-0.2,3.4,5.4,1.323529412,0.833333333,1.382352941,0.87037037,,3.6,N,N,,,56,NORMAL,4.5,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/2/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/2/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,99,-22,35,115,2.2,0.669565217,2.828571429,0.860869565,,95.5,N,N,,,39,NORMAL,77,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/2/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,21,8,6,35,4.833333333,0.828571429,3.5,0.6,,26,N,N,,,40,NORMAL,29,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/2/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,17,3,11,36,1.818181818,0.555555556,1.545454545,0.472222222,,34,N,N,,,41,NORMAL,20,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,30,3/16/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,4.7,0,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,,,90,NORMAL,4.7,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,30,3/16/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,30,3/16/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,99,-21,35,115,2.228571429,0.67826087,2.828571429,0.860869565,,94.5,N,N,,,74,NORMAL,78,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,30,3/16/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,21,2,6,35,3.833333333,0.657142857,3.5,0.6,,29.5,N,N,,,75,NORMAL,23,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,30,3/16/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,0,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,,,76,NORMAL,17,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,39,3/25/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.7,-0.4,3.4,5.4,1.264705882,0.796296296,1.382352941,0.87037037,Y,3.8,N,N,,Y,121,NORMAL,4.3,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,39,3/25/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.7,-0.4,3.4,5.4,1.264705882,0.796296296,1.382352941,0.87037037,Y,3.8,N,N,,Y,121,NORMAL,4.3,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,39,3/25/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,108,NORMAL,6.84,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,39,3/25/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,108,NORMAL,6.84,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,39,3/25/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,99,-31,35,115,1.942857143,0.591304348,2.828571429,0.860869565,Y,104.5,N,N,,Y,104,NORMAL,68,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,39,3/25/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,99,-31,35,115,1.942857143,0.591304348,2.828571429,0.860869565,Y,104.5,N,N,,Y,104,NORMAL,68,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,39,3/25/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,21,-2,6,35,3.166666667,0.542857143,3.5,0.6,Y,33.5,N,N,,Y,105,NORMAL,19,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,39,3/25/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,21,-2,6,35,3.166666667,0.542857143,3.5,0.6,Y,33.5,N,N,,Y,105,NORMAL,19,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,39,3/25/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,17,-3,11,36,1.272727273,0.388888889,1.545454545,0.472222222,Y,40,N,N,,Y,106,NORMAL,14,0,No
CDISCPILOT01,1188,01-701-1188,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/15/13,3/24/13,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,39,3/25/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,17,-3,11,36,1.272727273,0.388888889,1.545454545,0.472222222,Y,40,N,N,,Y,106,NORMAL,14,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-14,7/8/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.8,3.8,,3.4,5.4,1.117647059,0.703703704,1.117647059,0.703703704,,4.3,N,N,Y,,19,NORMAL,3.8,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-14,7/8/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-14,7/8/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,155,155,,35,115,4.428571429,1.347826087,4.428571429,1.347826087,,137.5,N,N,Y,,2,HIGH,155,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-14,7/8/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,,6,32,2.833333333,0.53125,2.833333333,0.53125,,31,N,N,Y,,3,NORMAL,17,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-14,7/8/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,18,,9,34,2,0.529411765,2,0.529411765,,33,N,N,Y,,4,NORMAL,18,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,17,8/7/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.1,3.8,0.3,3.4,5.4,1.205882353,0.759259259,1.117647059,0.703703704,,4,N,N,,,56,NORMAL,4.1,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,17,8/7/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,17,8/7/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,131,155,-24,35,115,3.742857143,1.139130435,4.428571429,1.347826087,,113.5,N,N,,,39,HIGH,131,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,17,8/7/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,32,2.5,0.46875,2.833333333,0.53125,,33,N,N,,,40,NORMAL,15,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,17,8/7/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,9,34,2.222222222,0.588235294,2,0.529411765,,31,N,N,,,41,NORMAL,20,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,31,8/21/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.2,3.8,0.4,3.4,5.4,1.235294118,0.777777778,1.117647059,0.703703704,,3.9,N,N,,,90,NORMAL,4.2,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,31,8/21/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,31,8/21/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,134,155,-21,35,115,3.828571429,1.165217391,4.428571429,1.347826087,,116.5,N,N,,,74,HIGH,134,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,31,8/21/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,17,-3,6,32,2.333333333,0.4375,2.833333333,0.53125,,34,N,N,,,75,NORMAL,14,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,31,8/21/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,9,34,2.222222222,0.588235294,2,0.529411765,,31,N,N,,,76,NORMAL,20,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,45,9/4/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.9,3.8,0.1,3.4,5.4,1.147058824,0.722222222,1.117647059,0.703703704,Y,4.2,N,N,,,125,NORMAL,3.9,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,45,9/4/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,Y,22.95,N,N,,,113,NORMAL,8.55,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,45,9/4/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,137,155,-18,35,115,3.914285714,1.191304348,4.428571429,1.347826087,,119.5,N,N,,,109,HIGH,137,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,45,9/4/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,32,2,0.375,2.833333333,0.53125,Y,36,N,N,,,110,NORMAL,12,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,45,9/4/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,18,-3,9,34,1.666666667,0.441176471,2,0.529411765,Y,36,N,N,,,111,NORMAL,15,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,64,9/23/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,3.8,0.7,3.4,5.4,1.323529412,0.833333333,1.117647059,0.703703704,,3.6,N,N,,,155,NORMAL,4.5,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,64,9/23/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,143,NORMAL,8.55,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,64,9/23/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,130,155,-25,35,115,3.714285714,1.130434783,4.428571429,1.347826087,,112.5,N,N,,,139,HIGH,130,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,64,9/23/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,17,2,6,32,3.166666667,0.59375,2.833333333,0.53125,,29,N,N,,,140,NORMAL,19,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,64,9/23/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,18,5,9,34,2.555555556,0.676470588,2,0.529411765,,28,N,N,,,141,NORMAL,23,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,10/14/12,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4,3.8,0.2,3.4,5.4,1.176470588,0.740740741,1.117647059,0.703703704,,4.1,N,N,,,186,NORMAL,4,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,10/14/12,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,173,NORMAL,10.26,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,10/14/12,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,138,155,-17,35,115,3.942857143,1.2,4.428571429,1.347826087,,120.5,N,N,,,169,HIGH,138,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,10/14/12,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,17,-3,6,32,2.333333333,0.4375,2.833333333,0.53125,,34,N,N,,,170,NORMAL,14,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,85,10/14/12,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,18,1,9,34,2.111111111,0.558823529,2,0.529411765,,32,N,N,,,171,NORMAL,19,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,117,11/15/12,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,3.8,0.2,3.4,5.4,1.176470588,0.740740741,1.117647059,0.703703704,,4.1,N,N,,,220,NORMAL,4,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,117,11/15/12,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,208,NORMAL,10.26,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,117,11/15/12,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,124,155,-31,35,115,3.542857143,1.07826087,4.428571429,1.347826087,,106.5,N,N,,,204,HIGH,124,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,117,11/15/12,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,17,-4,6,32,2.166666667,0.40625,2.833333333,0.53125,,35,N,N,,,205,NORMAL,13,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,117,11/15/12,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,9,34,2.222222222,0.588235294,2,0.529411765,,31,N,N,,,206,NORMAL,20,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,145,12/13/12,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4,3.8,0.2,3.4,5.4,1.176470588,0.740740741,1.117647059,0.703703704,,4.1,N,N,,,250,NORMAL,4,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,145,12/13/12,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,238,NORMAL,10.26,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,145,12/13/12,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,128,155,-27,35,115,3.657142857,1.113043478,4.428571429,1.347826087,,110.5,N,N,,,234,HIGH,128,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,145,12/13/12,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,32,2.5,0.46875,2.833333333,0.53125,,33,N,N,,,235,NORMAL,15,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,145,12/13/12,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,18,1,9,34,2.111111111,0.558823529,2,0.529411765,,32,N,N,,,236,NORMAL,19,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,174,1/11/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,3.8,0.1,3.4,5.4,1.147058824,0.722222222,1.117647059,0.703703704,,4.2,N,N,,Y,281,NORMAL,3.9,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,174,1/11/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,3.8,0.1,3.4,5.4,1.147058824,0.722222222,1.117647059,0.703703704,,4.2,N,N,,Y,281,NORMAL,3.9,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,174,1/11/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,268,NORMAL,8.55,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,174,1/11/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,Y,268,NORMAL,8.55,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,174,1/11/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,139,155,-16,35,115,3.971428571,1.208695652,4.428571429,1.347826087,Y,121.5,N,N,,Y,264,HIGH,139,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,174,1/11/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,139,155,-16,35,115,3.971428571,1.208695652,4.428571429,1.347826087,Y,121.5,N,N,,Y,264,HIGH,139,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,174,1/11/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,17,2,6,32,3.166666667,0.59375,2.833333333,0.53125,,29,N,N,,Y,265,NORMAL,19,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,174,1/11/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,17,2,6,32,3.166666667,0.59375,2.833333333,0.53125,,29,N,N,,Y,265,NORMAL,19,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,174,1/11/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,18,6,9,34,2.666666667,0.705882353,2,0.529411765,,27,N,N,,Y,266,NORMAL,24,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,174,1/11/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,18,6,9,34,2.666666667,0.705882353,2,0.529411765,,27,N,N,,Y,266,NORMAL,24,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,1/20/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4,3.8,0.2,3.4,5.4,1.176470588,0.740740741,1.117647059,0.703703704,,4.1,N,N,,,315,NORMAL,4,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,1/20/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,303,NORMAL,8.55,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,1/20/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,116,155,-39,35,115,3.314285714,1.008695652,4.428571429,1.347826087,,98.5,N,N,,,299,HIGH,116,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,1/20/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,17,-1,6,32,2.666666667,0.5,2.833333333,0.53125,,32,N,N,,,300,NORMAL,16,0,No
CDISCPILOT01,1192,01-701-1192,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/22/12,1/20/13,80,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,183,1/20/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,9,34,2.222222222,0.588235294,2,0.529411765,,31,N,N,,,301,NORMAL,20,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-8,1/25/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-8,1/25/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,Y,,6,NORMAL,5.13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-8,1/25/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,87,87,,35,115,2.485714286,0.756521739,2.485714286,0.756521739,,85.5,N,N,Y,,2,NORMAL,87,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-8,1/25/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,Y,,3,NORMAL,13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-8,1/25/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,22,2/23/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,5.1,4.1,1,3.4,5.4,1.5,0.944444444,1.205882353,0.759259259,,3.4,N,N,,,56,NORMAL,5.1,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,22,2/23/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,Y,26.37,N,N,,,43,NORMAL,5.13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,22,2/23/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,87,3,35,115,2.571428571,0.782608696,2.485714286,0.756521739,,82.5,N,N,,,39,NORMAL,90,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,22,2/23/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,22,2/23/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,41,NORMAL,20,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,3/2/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.8,4.1,0.7,3.4,5.4,1.411764706,0.888888889,1.205882353,0.759259259,,3.3,N,N,,,90,NORMAL,4.8,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,3/2/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,3/2/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,82,87,-5,35,115,2.342857143,0.713043478,2.485714286,0.756521739,,90.5,N,N,,,74,NORMAL,82,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,3/2/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,13,-3,6,32,1.666666667,0.3125,2.166666667,0.40625,Y,38,N,N,,,75,NORMAL,10,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,3/2/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,20,-4,9,34,1.777777778,0.470588235,2.222222222,0.588235294,,35,N,N,,,76,NORMAL,16,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,3/16/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.8,4.1,0.7,3.4,5.4,1.411764706,0.888888889,1.205882353,0.759259259,,3.3,N,N,,,120,NORMAL,4.8,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,3/16/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,108,NORMAL,6.84,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,3/16/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,82,87,-5,35,115,2.342857143,0.713043478,2.485714286,0.756521739,,90.5,N,N,,,104,NORMAL,82,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,3/16/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,13,-1,6,32,2,0.375,2.166666667,0.40625,,36,N,N,,,105,NORMAL,12,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,3/16/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,,28,N,N,,,106,NORMAL,23,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,3/30/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,Y,4,N,N,,,150,NORMAL,4.1,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,3/30/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,138,NORMAL,6.84,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,3/30/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,87,3,35,115,2.571428571,0.782608696,2.485714286,0.756521739,,82.5,N,N,,,134,NORMAL,90,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,3/30/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,13,-2,6,32,1.833333333,0.34375,2.166666667,0.40625,,37,N,N,,,135,NORMAL,11,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,3/30/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,9,34,2.111111111,0.558823529,2.222222222,0.588235294,,32,N,N,,,136,NORMAL,19,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,97,5/9/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,4.1,0.1,3.4,5.4,1.235294118,0.777777778,1.205882353,0.759259259,,3.9,N,N,,,181,NORMAL,4.2,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,97,5/9/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,,168,NORMAL,5.13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,97,5/9/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,87,-6,35,115,2.314285714,0.704347826,2.485714286,0.756521739,,91.5,N,N,,,164,NORMAL,81,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,97,5/9/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,13,3,6,32,2.666666667,0.5,2.166666667,0.40625,,32,N,N,,,165,NORMAL,16,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,97,5/9/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,20,2,9,34,2.444444444,0.647058824,2.222222222,0.588235294,,29,N,N,,,166,NORMAL,22,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,5/25/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.9,4.1,0.8,3.4,5.4,1.441176471,0.907407407,1.205882353,0.759259259,,3.2,N,N,,,215,NORMAL,4.9,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,5/25/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,203,NORMAL,6.84,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,5/25/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,87,-6,35,115,2.314285714,0.704347826,2.485714286,0.756521739,,91.5,N,N,,,199,NORMAL,81,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,5/25/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,13,-2,6,32,1.833333333,0.34375,2.166666667,0.40625,,37,N,N,,,200,NORMAL,11,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,5/25/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,9,34,2,0.529411765,2.222222222,0.588235294,,33,N,N,,,201,NORMAL,18,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,6/22/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.9,4.1,0.8,3.4,5.4,1.441176471,0.907407407,1.205882353,0.759259259,,3.2,N,N,,,245,NORMAL,4.9,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,6/22/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,,233,NORMAL,5.13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,6/22/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,87,-3,35,115,2.4,0.730434783,2.485714286,0.756521739,,88.5,N,N,,,229,NORMAL,84,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,6/22/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,,,230,NORMAL,13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,6/22/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,20,2,9,34,2.444444444,0.647058824,2.222222222,0.588235294,,29,N,N,,,231,NORMAL,22,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,171,7/22/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.1,0.4,3.4,5.4,1.323529412,0.833333333,1.205882353,0.759259259,,3.6,N,N,,Y,276,NORMAL,4.5,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,171,7/22/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.1,0.4,3.4,5.4,1.323529412,0.833333333,1.205882353,0.759259259,,3.6,N,N,,Y,276,NORMAL,4.5,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,171,7/22/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,Y,263,NORMAL,5.13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,171,7/22/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,Y,263,NORMAL,5.13,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,171,7/22/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,87,-8,35,115,2.257142857,0.686956522,2.485714286,0.756521739,Y,93.5,N,N,,Y,259,NORMAL,79,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,171,7/22/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,87,-8,35,115,2.257142857,0.686956522,2.485714286,0.756521739,Y,93.5,N,N,,Y,259,NORMAL,79,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,171,7/22/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,13,-3,6,32,1.666666667,0.3125,2.166666667,0.40625,,38,N,N,,Y,260,NORMAL,10,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,171,7/22/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,13,-3,6,32,1.666666667,0.3125,2.166666667,0.40625,,38,N,N,,Y,260,NORMAL,10,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,171,7/22/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,Y,36,N,N,,Y,261,NORMAL,15,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,171,7/22/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,Y,36,N,N,,Y,261,NORMAL,15,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,8/3/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.5,4.1,0.4,3.4,5.4,1.323529412,0.833333333,1.205882353,0.759259259,,3.6,N,N,,,310,NORMAL,4.5,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,8/3/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,8/3/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,87,-7,35,115,2.285714286,0.695652174,2.485714286,0.756521739,,92.5,N,N,,,294,NORMAL,80,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,8/3/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,295,NORMAL,14,0,No
CDISCPILOT01,1203,01-701-1203,Placebo,0,Placebo,0,2/2/13,8/3/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,8/3/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,9,34,2.111111111,0.558823529,2.222222222,0.588235294,,32,N,N,,,296,NORMAL,19,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,10/30/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,10/30/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,18.81,18.81,,3,21,6.27,0.895714286,6.27,0.895714286,,17.31,N,N,Y,,6,NORMAL,18.81,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,10/30/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,106,106,,35,115,3.028571429,0.92173913,3.028571429,0.92173913,,88.5,N,N,Y,,2,NORMAL,106,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,10/30/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,32,3.166666667,0.59375,3.166666667,0.59375,,29,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,10/30/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 2,2,14,11/28/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.6,3.9,-0.3,3.4,5.4,1.058823529,0.666666667,1.147058824,0.722222222,Y,4.5,N,N,,,56,NORMAL,3.6,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 2,2,14,11/28/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,25.65,18.81,6.84,3,21,8.55,1.221428571,6.27,0.895714286,Y,24.15,N,N,,,43,HIGH,25.65,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 2,2,14,11/28/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,103,106,-3,35,115,2.942857143,0.895652174,3.028571429,0.92173913,,85.5,N,N,,,39,NORMAL,103,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 2,2,14,11/28/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,0,6,32,3.166666667,0.59375,3.166666667,0.59375,,29,N,N,,,40,NORMAL,19,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 2,2,14,11/28/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,10,20,-10,9,34,1.111111111,0.294117647,2.222222222,0.588235294,Y,41,N,N,,,41,NORMAL,10,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 4,4,27,12/11/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.2,3.9,0.3,3.4,5.4,1.235294118,0.777777778,1.147058824,0.722222222,,3.9,N,N,,,90,NORMAL,4.2,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 4,4,27,12/11/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,15.39,18.81,-3.42,3,21,5.13,0.732857143,6.27,0.895714286,,16.11,N,N,,,78,NORMAL,15.39,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 4,4,27,12/11/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,136,106,30,35,115,3.885714286,1.182608696,3.028571429,0.92173913,,118.5,N,N,,,74,HIGH,136,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 4,4,27,12/11/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,19,-5,6,32,2.333333333,0.4375,3.166666667,0.59375,Y,34,N,N,,,75,NORMAL,14,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 4,4,27,12/11/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,,36,N,N,,,76,NORMAL,15,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 6,6,41,12/25/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,3.9,0.4,3.4,5.4,1.264705882,0.796296296,1.147058824,0.722222222,,3.8,N,N,,,120,NORMAL,4.3,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 6,6,41,12/25/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,15.39,18.81,-3.42,3,21,5.13,0.732857143,6.27,0.895714286,,16.11,N,N,,,108,NORMAL,15.39,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 6,6,41,12/25/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,132,106,26,35,115,3.771428571,1.147826087,3.028571429,0.92173913,,114.5,N,N,,,104,HIGH,132,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 6,6,41,12/25/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,19,-4,6,32,2.5,0.46875,3.166666667,0.59375,,33,N,N,,,105,NORMAL,15,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 6,6,41,12/25/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,,36,N,N,,,106,NORMAL,15,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 8,8,55,1/8/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.6,3.9,-0.3,3.4,5.4,1.058823529,0.666666667,1.147058824,0.722222222,,4.5,N,N,,Y,150,NORMAL,3.6,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,55,1/8/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.6,3.9,-0.3,3.4,5.4,1.058823529,0.666666667,1.147058824,0.722222222,,4.5,N,N,,Y,150,NORMAL,3.6,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 8,8,55,1/8/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,23.94,18.81,5.13,3,21,7.98,1.14,6.27,0.895714286,,22.44,N,N,,Y,138,HIGH,23.94,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,55,1/8/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,23.94,18.81,5.13,3,21,7.98,1.14,6.27,0.895714286,,22.44,N,N,,Y,138,HIGH,23.94,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 8,8,55,1/8/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,183,106,77,35,115,5.228571429,1.591304348,3.028571429,0.92173913,Y,165.5,H,N,,Y,134,HIGH,183,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,55,1/8/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,183,106,77,35,115,5.228571429,1.591304348,3.028571429,0.92173913,Y,165.5,H,N,,Y,134,HIGH,183,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 8,8,55,1/8/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,32,3.5,0.65625,3.166666667,0.59375,,27,N,N,,Y,135,NORMAL,21,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,55,1/8/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,32,3.5,0.65625,3.166666667,0.59375,,27,N,N,,Y,135,NORMAL,21,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y, Week 8,8,55,1/8/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,Y,136,NORMAL,17,0,No
CDISCPILOT01,1211,01-701-1211,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/15/12,1/12/13,76,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,55,1/8/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,Y,136,NORMAL,17,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-10,3/20/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,20,NORMAL,4.3,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-10,3/20/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,Y,,7,NORMAL,5.13,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-10,3/20/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,94,94,,35,115,2.685714286,0.817391304,2.685714286,0.817391304,,78.5,N,N,Y,,2,NORMAL,94,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-10,3/20/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,18,,6,35,3,0.514285714,3,0.514285714,,34.5,N,N,Y,,3,NORMAL,18,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-10,3/20/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,Y,,5,NORMAL,24,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,23,4/21/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.7,4.3,0.4,3.4,5.4,1.382352941,0.87037037,1.264705882,0.796296296,,3.4,N,N,,,57,NORMAL,4.7,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,23,4/21/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,5.13,6.84,3,21,3.99,0.57,1.71,0.244285714,Y,19.53,N,N,,,44,NORMAL,11.97,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,23,4/21/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,94,-39,35,115,1.571428571,0.47826087,2.685714286,0.817391304,,117.5,N,N,,,40,NORMAL,55,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,23,4/21/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,30,18,12,6,35,5,0.857142857,3,0.514285714,,27,N,N,,,41,NORMAL,30,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,23,4/21/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,24,7,11,36,2.818181818,0.861111111,2.181818182,0.666666667,,25.5,N,N,,,42,NORMAL,31,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,30,4/28/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.8,4.3,0.5,3.4,5.4,1.411764706,0.888888889,1.264705882,0.796296296,,3.3,N,N,,,91,NORMAL,4.8,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,30,4/28/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,15.39,5.13,10.26,3,21,5.13,0.732857143,1.71,0.244285714,,16.11,N,N,,,79,NORMAL,15.39,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,30,4/28/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,94,-30,35,115,1.828571429,0.556521739,2.685714286,0.817391304,,108.5,N,N,,,75,NORMAL,64,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,30,4/28/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,18,8,6,35,4.333333333,0.742857143,3,0.514285714,,26.5,N,N,,,76,NORMAL,26,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,30,4/28/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,,77,NORMAL,23,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,40,5/8/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,,121,NORMAL,4.5,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,40,5/8/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,17.1,5.13,11.97,3,21,5.7,0.814285714,1.71,0.244285714,,15.6,N,N,,,109,NORMAL,17.1,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,40,5/8/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,94,-30,35,115,1.828571429,0.556521739,2.685714286,0.817391304,,108.5,N,N,,,105,NORMAL,64,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,40,5/8/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,18,2,6,35,3.333333333,0.571428571,3,0.514285714,,32.5,N,N,,,106,NORMAL,20,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,40,5/8/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,24,-4,11,36,1.818181818,0.555555556,2.181818182,0.666666667,,34,N,N,,,107,NORMAL,20,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,58,5/26/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,,151,NORMAL,4.5,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,58,5/26/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,13.68,5.13,8.55,3,21,4.56,0.651428571,1.71,0.244285714,,17.82,N,N,,,139,NORMAL,13.68,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,58,5/26/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,94,-43,35,115,1.457142857,0.443478261,2.685714286,0.817391304,,121.5,N,N,,,135,NORMAL,51,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,58,5/26/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,18,4,6,35,3.666666667,0.628571429,3,0.514285714,,30.5,N,N,,,136,NORMAL,22,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,58,5/26/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,24,2,11,36,2.363636364,0.722222222,2.181818182,0.666666667,,28,N,N,,,137,NORMAL,26,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,100,7/7/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.6,4.3,0.3,3.4,5.4,1.352941176,0.851851852,1.264705882,0.796296296,,3.5,N,N,,,182,NORMAL,4.6,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,100,7/7/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,20.52,5.13,15.39,3,21,6.84,0.977142857,1.71,0.244285714,,19.02,N,N,,,169,NORMAL,20.52,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,100,7/7/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,94,-35,35,115,1.685714286,0.513043478,2.685714286,0.817391304,,113.5,N,N,,,165,NORMAL,59,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,100,7/7/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,40,18,22,6,35,6.666666667,1.142857143,3,0.514285714,Y,37,N,N,,,166,HIGH,40,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,100,7/7/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,24,8,11,36,2.909090909,0.888888889,2.181818182,0.666666667,,26.5,N,N,,,167,NORMAL,32,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,120,7/27/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,,3.9,N,N,,,216,NORMAL,4.2,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,120,7/27/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,15.39,5.13,10.26,3,21,5.13,0.732857143,1.71,0.244285714,,16.11,N,N,,,204,NORMAL,15.39,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,120,7/27/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,94,-31,35,115,1.8,0.547826087,2.685714286,0.817391304,,109.5,N,N,,,200,NORMAL,63,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,120,7/27/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,18,5,6,35,3.833333333,0.657142857,3,0.514285714,,29.5,N,N,,,201,NORMAL,23,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,120,7/27/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,,202,NORMAL,23,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,142,8/18/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.7,4.3,-0.6,3.4,5.4,1.088235294,0.685185185,1.264705882,0.796296296,Y,4.4,N,N,,,246,NORMAL,3.7,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,142,8/18/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,13.68,5.13,8.55,3,21,4.56,0.651428571,1.71,0.244285714,,17.82,N,N,,,234,NORMAL,13.68,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,142,8/18/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,94,-42,35,115,1.485714286,0.452173913,2.685714286,0.817391304,,120.5,N,N,,,230,NORMAL,52,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,142,8/18/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,18,-2,6,35,2.666666667,0.457142857,3,0.514285714,,36.5,N,N,,,231,NORMAL,16,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,142,8/18/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,24,-5,11,36,1.727272727,0.527777778,2.181818182,0.666666667,Y,35,N,N,,,232,NORMAL,19,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,165,9/10/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,,3.9,N,N,,Y,277,NORMAL,4.2,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,165,9/10/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,,3.9,N,N,,Y,277,NORMAL,4.2,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,165,9/10/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,17.1,5.13,11.97,3,21,5.7,0.814285714,1.71,0.244285714,,15.6,N,N,,Y,264,NORMAL,17.1,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,165,9/10/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,17.1,5.13,11.97,3,21,5.7,0.814285714,1.71,0.244285714,,15.6,N,N,,Y,264,NORMAL,17.1,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,165,9/10/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,94,-44,35,115,1.428571429,0.434782609,2.685714286,0.817391304,Y,122.5,N,N,,Y,260,NORMAL,50,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,165,9/10/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,94,-44,35,115,1.428571429,0.434782609,2.685714286,0.817391304,Y,122.5,N,N,,Y,260,NORMAL,50,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,165,9/10/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,18,7,6,35,4.166666667,0.714285714,3,0.514285714,,27.5,N,N,,Y,261,NORMAL,25,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,165,9/10/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,18,7,6,35,4.166666667,0.714285714,3,0.514285714,,27.5,N,N,,Y,261,NORMAL,25,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,165,9/10/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,0,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,,Y,262,NORMAL,24,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,165,9/10/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,0,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,,Y,262,NORMAL,24,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,177,9/22/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,311,NORMAL,4.3,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,177,9/22/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,11.97,5.13,6.84,3,21,3.99,0.57,1.71,0.244285714,,19.53,N,N,,,299,NORMAL,11.97,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,177,9/22/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,94,-27,35,115,1.914285714,0.582608696,2.685714286,0.817391304,,105.5,N,N,,,295,NORMAL,67,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,177,9/22/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,18,5,6,35,3.833333333,0.657142857,3,0.514285714,,29.5,N,N,,,296,NORMAL,23,0,No
CDISCPILOT01,1234,01-701-1234,Placebo,0,Placebo,0,3/30/13,9/22/13,69,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,177,9/22/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,24,2,11,36,2.363636364,0.722222222,2.181818182,0.666666667,,28,N,N,,,297,NORMAL,26,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-14,12/28/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.4,4.4,,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,Y,,19,NORMAL,4.4,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-14,12/28/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,39.33,39.33,,3,21,13.11,1.872857143,13.11,1.872857143,,37.83,H,H,Y,,6,HIGH,39.33,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-14,12/28/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,82,82,,31,110,2.64516129,0.745454545,2.64516129,0.745454545,,83,N,N,Y,,2,NORMAL,82,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-14,12/28/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,64,64,,6,43,10.66666667,1.488372093,10.66666667,1.488372093,,61,N,N,Y,,3,HIGH,64,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-14,12/28/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,38,38,,11,36,3.454545455,1.055555556,3.454545455,1.055555556,,32.5,N,N,Y,,4,HIGH,38,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, .,,-5,1/6/14,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,34.2,39.33,-5.13,3,21,11.4,1.628571429,13.11,1.872857143,,32.7,H,H,,,42,HIGH,34.2,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, .,,-5,1/6/14,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,82,-2,31,110,2.580645161,0.727272727,2.64516129,0.745454545,,85,N,N,,,39,NORMAL,80,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, .,,-5,1/6/14,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,61,64,-3,6,43,10.16666667,1.418604651,10.66666667,1.488372093,,58,N,N,,,40,HIGH,61,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, .,,-5,1/6/14,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,36,38,-2,11,36,3.272727273,1,3.454545455,1.055555556,,30.5,N,N,,,41,NORMAL,36,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,1/25/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,71,NORMAL,4.4,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,1/25/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,18.81,39.33,-20.52,3,21,6.27,0.895714286,13.11,1.872857143,,17.31,N,H,,,58,NORMAL,18.81,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,1/25/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,82,13,31,110,3.064516129,0.863636364,2.64516129,0.745454545,,79.5,N,N,,,54,NORMAL,95,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,1/25/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,47,64,-17,6,43,7.833333333,1.093023256,10.66666667,1.488372093,,44,N,N,,,55,HIGH,47,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 2,2,15,1/25/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,38,-12,11,36,2.363636364,0.722222222,3.454545455,1.055555556,,28,N,N,,,56,NORMAL,26,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,2/8/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.4,-0.1,3.4,5.4,1.264705882,0.796296296,1.294117647,0.814814815,,3.8,N,N,,,105,NORMAL,4.3,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,2/8/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,34.2,39.33,-5.13,3,21,11.4,1.628571429,13.11,1.872857143,Y,32.7,H,H,,,93,HIGH,34.2,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,2/8/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,82,7,31,110,2.870967742,0.809090909,2.64516129,0.745454545,,76,N,N,,,89,NORMAL,89,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,2/8/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,61,64,-3,6,43,10.16666667,1.418604651,10.66666667,1.488372093,,58,N,N,,,90,HIGH,61,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 4,4,29,2/8/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,43,38,5,11,36,3.909090909,1.194444444,3.454545455,1.055555556,Y,37.5,N,N,,,91,HIGH,43,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 6,6,40,2/19/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,135,NORMAL,4.2,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 6,6,40,2/19/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,25.65,39.33,-13.68,3,21,8.55,1.221428571,13.11,1.872857143,,24.15,N,H,,,123,HIGH,25.65,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 6,6,40,2/19/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,82,7,31,110,2.870967742,0.809090909,2.64516129,0.745454545,,76,N,N,,,119,NORMAL,89,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 6,6,40,2/19/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,60,64,-4,6,43,10,1.395348837,10.66666667,1.488372093,,57,N,N,,,120,HIGH,60,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 6,6,40,2/19/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,38,-6,11,36,2.909090909,0.888888889,3.454545455,1.055555556,,26.5,N,N,,,121,NORMAL,32,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 8,8,55,3/6/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,165,NORMAL,4.4,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 8,8,55,3/6/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,23.94,39.33,-15.39,3,21,7.98,1.14,13.11,1.872857143,,22.44,N,H,,,153,HIGH,23.94,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 8,8,55,3/6/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,82,-5,31,110,2.483870968,0.7,2.64516129,0.745454545,,88,N,N,,,149,NORMAL,77,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 8,8,55,3/6/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,71,64,7,6,43,11.83333333,1.651162791,10.66666667,1.488372093,Y,68,H,N,,,150,HIGH,71,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 8,8,55,3/6/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,38,-3,11,36,3.181818182,0.972222222,3.454545455,1.055555556,,29.5,N,N,,,151,NORMAL,35,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 12,12,82,4/2/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.4,0,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,,,196,NORMAL,4.4,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 12,12,82,4/2/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,15.39,39.33,-23.94,3,21,5.13,0.732857143,13.11,1.872857143,,16.11,N,H,,,183,NORMAL,15.39,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 12,12,82,4/2/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,82,8,31,110,2.903225806,0.818181818,2.64516129,0.745454545,,75,N,N,,,179,NORMAL,90,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 12,12,82,4/2/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,70,64,6,6,43,11.66666667,1.627906977,10.66666667,1.488372093,,67,H,N,,,180,HIGH,70,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 12,12,82,4/2/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,38,-3,11,36,3.181818182,0.972222222,3.454545455,1.055555556,,29.5,N,N,,,181,NORMAL,35,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 16,16,112,5/2/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.5,4.4,0.1,3.4,5.4,1.323529412,0.833333333,1.294117647,0.814814815,,3.6,N,N,,,230,NORMAL,4.5,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 16,16,112,5/2/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,23.94,39.33,-15.39,3,21,7.98,1.14,13.11,1.872857143,,22.44,N,H,,,218,HIGH,23.94,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 16,16,112,5/2/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,82,-7,31,110,2.419354839,0.681818182,2.64516129,0.745454545,,90,N,N,,,214,NORMAL,75,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 16,16,112,5/2/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,35,64,-29,6,43,5.833333333,0.813953488,10.66666667,1.488372093,,32,N,N,,,215,NORMAL,35,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 16,16,112,5/2/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,38,-12,11,36,2.363636364,0.722222222,3.454545455,1.055555556,,28,N,N,,,216,NORMAL,26,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 20,20,138,5/28/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4,4.4,-0.4,3.4,5.4,1.176470588,0.740740741,1.294117647,0.814814815,Y,4.1,N,N,,,260,NORMAL,4,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 20,20,138,5/28/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,25.65,39.33,-13.68,3,21,8.55,1.221428571,13.11,1.872857143,,24.15,N,H,,,248,HIGH,25.65,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 20,20,138,5/28/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,82,1,31,110,2.677419355,0.754545455,2.64516129,0.745454545,,82,N,N,,,244,NORMAL,83,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 20,20,138,5/28/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,35,64,-29,6,43,5.833333333,0.813953488,10.66666667,1.488372093,,32,N,N,,,245,NORMAL,35,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 20,20,138,5/28/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,38,-15,11,36,2.090909091,0.638888889,3.454545455,1.055555556,,31,N,N,,,246,NORMAL,23,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 24,24,168,6/27/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,Y,291,NORMAL,4.2,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,168,6/27/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,Y,291,NORMAL,4.2,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 24,24,168,6/27/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,30.78,39.33,-8.55,3,21,10.26,1.465714286,13.11,1.872857143,,29.28,N,H,,Y,278,HIGH,30.78,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,168,6/27/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,30.78,39.33,-8.55,3,21,10.26,1.465714286,13.11,1.872857143,,29.28,N,H,,Y,278,HIGH,30.78,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 24,24,168,6/27/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,71,82,-11,31,110,2.290322581,0.645454545,2.64516129,0.745454545,Y,94,N,N,,Y,274,NORMAL,71,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,168,6/27/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,71,82,-11,31,110,2.290322581,0.645454545,2.64516129,0.745454545,Y,94,N,N,,Y,274,NORMAL,71,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 24,24,168,6/27/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,43,64,-21,6,43,7.166666667,1,10.66666667,1.488372093,,40,N,N,,Y,275,NORMAL,43,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,168,6/27/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,43,64,-21,6,43,7.166666667,1,10.66666667,1.488372093,,40,N,N,,Y,275,NORMAL,43,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 24,24,168,6/27/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,38,-10,11,36,2.545454545,0.777777778,3.454545455,1.055555556,,26,N,N,,Y,276,NORMAL,28,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,168,6/27/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,38,-10,11,36,2.545454545,0.777777778,3.454545455,1.055555556,,26,N,N,,Y,276,NORMAL,28,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,7/11/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,325,NORMAL,4.2,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,7/11/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,18.81,39.33,-20.52,3,21,6.27,0.895714286,13.11,1.872857143,,17.31,N,H,,,313,NORMAL,18.81,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,7/11/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,82,-9,31,110,2.35483871,0.663636364,2.64516129,0.745454545,,92,N,N,,,309,NORMAL,73,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,7/11/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,39,64,-25,6,43,6.5,0.906976744,10.66666667,1.488372093,,36,N,N,,,310,NORMAL,39,0,No
CDISCPILOT01,1239,01-701-1239,Xanomeline High Dose,81,Xanomeline High Dose,81,1/11/14,7/10/14,56,<65,1,WHITE,1,M,Y,,Y, Week 26,26,182,7/11/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,38,-15,11,36,2.090909091,0.638888889,3.454545455,1.055555556,,31,N,N,,,311,NORMAL,23,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Baseline,0,-13,1/25/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Baseline,0,-13,1/25/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Baseline,0,-13,1/25/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,38,38,,35,115,1.085714286,0.330434783,1.085714286,0.330434783,,134.5,N,N,Y,,2,NORMAL,38,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Baseline,0,-13,1/25/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,43,3.166666667,0.441860465,3.166666667,0.441860465,,45.5,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Baseline,0,-13,1/25/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,28,,11,36,2.545454545,0.777777778,2.545454545,0.777777778,,26,N,N,Y,,4,NORMAL,28,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 2,2,16,2/22/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,Y,4,N,N,,,56,NORMAL,4.1,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 2,2,16,2/22/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 2,2,16,2/22/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,36,38,-2,35,115,1.028571429,0.313043478,1.085714286,0.330434783,,136.5,N,N,,,39,NORMAL,36,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 2,2,16,2/22/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,0,6,43,3.166666667,0.441860465,3.166666667,0.441860465,,45.5,N,N,,,40,NORMAL,19,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 2,2,16,2/22/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,28,-1,11,36,2.454545455,0.75,2.545454545,0.777777778,,27,N,N,,,41,NORMAL,27,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 4,4,29,3/7/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,,3.9,N,N,,,90,NORMAL,4.2,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 4,4,29,3/7/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 4,4,29,3/7/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,36,38,-2,35,115,1.028571429,0.313043478,1.085714286,0.330434783,,136.5,N,N,,,74,NORMAL,36,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 4,4,29,3/7/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,19,1,6,43,3.333333333,0.465116279,3.166666667,0.441860465,,44.5,N,N,,,75,NORMAL,20,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 4,4,29,3/7/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,28,-1,11,36,2.454545455,0.75,2.545454545,0.777777778,,27,N,N,,,76,NORMAL,27,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 6,6,44,3/22/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,120,NORMAL,4.3,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 6,6,44,3/22/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 6,6,44,3/22/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,34,38,-4,35,115,0.971428571,0.295652174,1.085714286,0.330434783,Y,138.5,N,N,,,104,LOW,34,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 6,6,44,3/22/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,19,3,6,43,3.666666667,0.511627907,3.166666667,0.441860465,,42.5,N,N,,,105,NORMAL,22,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 6,6,44,3/22/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,28,-3,11,36,2.272727273,0.694444444,2.545454545,0.777777778,Y,29,N,N,,,106,NORMAL,25,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 8,8,58,4/5/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,,150,NORMAL,4.4,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 8,8,58,4/5/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,Y,24.66,N,N,,,138,NORMAL,6.84,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 8,8,58,4/5/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,41,38,3,35,115,1.171428571,0.356521739,1.085714286,0.330434783,,131.5,N,N,,,134,NORMAL,41,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 8,8,58,4/5/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,43,3.5,0.488372093,3.166666667,0.441860465,,43.5,N,N,,,135,NORMAL,21,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 8,8,58,4/5/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,28,2,11,36,2.727272727,0.833333333,2.545454545,0.777777778,,24.5,N,N,,,136,NORMAL,30,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 12,12,86,5/3/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,168,NORMAL,8.55,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 12,12,86,5/3/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,37,38,-1,35,115,1.057142857,0.32173913,1.085714286,0.330434783,,135.5,N,N,,,164,NORMAL,37,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 12,12,86,5/3/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,19,-4,6,43,2.5,0.348837209,3.166666667,0.441860465,Y,49.5,N,N,,,165,NORMAL,15,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 12,12,86,5/3/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,28,-2,11,36,2.363636364,0.722222222,2.545454545,0.777777778,,28,N,N,,,166,NORMAL,26,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 16,16,128,6/14/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,Y,213,NORMAL,4.1,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y,End of Treatment,99,128,6/14/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,Y,213,NORMAL,4.1,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 16,16,128,6/14/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,Y,200,NORMAL,8.55,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y,End of Treatment,99,128,6/14/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,Y,200,NORMAL,8.55,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 16,16,128,6/14/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,37,38,-1,35,115,1.057142857,0.32173913,1.085714286,0.330434783,,135.5,N,N,,Y,196,NORMAL,37,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y,End of Treatment,99,128,6/14/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,37,38,-1,35,115,1.057142857,0.32173913,1.085714286,0.330434783,,135.5,N,N,,Y,196,NORMAL,37,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 16,16,128,6/14/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,0,6,43,3.166666667,0.441860465,3.166666667,0.441860465,,45.5,N,N,,Y,197,NORMAL,19,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y,End of Treatment,99,128,6/14/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,0,6,43,3.166666667,0.441860465,3.166666667,0.441860465,,45.5,N,N,,Y,197,NORMAL,19,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y, Week 16,16,128,6/14/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,28,1,11,36,2.636363636,0.805555556,2.545454545,0.777777778,,25,N,N,,Y,198,NORMAL,29,0,No
CDISCPILOT01,1275,01-701-1275,Xanomeline High Dose,81,Xanomeline High Dose,81,2/7/14,5/31/14,61,<65,1,AMERICAN INDIAN OR ALASKA NATIVE,6,M,N,,Y,End of Treatment,99,128,6/14/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,28,1,11,36,2.636363636,0.805555556,2.545454545,0.777777778,,25,N,N,,Y,198,NORMAL,29,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-8,1/17/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.8,3.8,,3.4,5.4,1.117647059,0.703703704,1.117647059,0.703703704,,4.3,N,N,Y,,19,NORMAL,3.8,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-8,1/17/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-8,1/17/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,51,,31,110,1.64516129,0.463636364,1.64516129,0.463636364,,114,N,N,Y,,2,NORMAL,51,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-8,1/17/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,,6,34,3.5,0.617647059,3.5,0.617647059,,30,N,N,Y,,3,NORMAL,21,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-8,1/17/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 2,2,18,2/11/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.7,3.8,-0.1,3.4,5.4,1.088235294,0.685185185,1.117647059,0.703703704,,4.4,N,N,,,56,NORMAL,3.7,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 2,2,18,2/11/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 2,2,18,2/11/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,51,6,31,110,1.838709677,0.518181818,1.64516129,0.463636364,,108,N,N,,,39,NORMAL,57,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 2,2,18,2/11/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,21,6,6,34,4.5,0.794117647,3.5,0.617647059,,24,N,N,,,40,NORMAL,27,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 2,2,18,2/11/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,33,25,8,9,34,3.666666667,0.970588235,2.777777778,0.735294118,,28.5,N,N,,,41,NORMAL,33,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 4,4,27,2/20/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.8,3.8,0,3.4,5.4,1.117647059,0.703703704,1.117647059,0.703703704,,4.3,N,N,,,90,NORMAL,3.8,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 4,4,27,2/20/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,Y,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 4,4,27,2/20/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,51,14,31,110,2.096774194,0.590909091,1.64516129,0.463636364,,100,N,N,,,74,NORMAL,65,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 4,4,27,2/20/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,21,1,6,34,3.666666667,0.647058824,3.5,0.617647059,,29,N,N,,,75,NORMAL,22,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 4,4,27,2/20/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,25,-4,9,34,2.333333333,0.617647059,2.777777778,0.735294118,Y,30,N,N,,,76,NORMAL,21,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 6,6,41,3/6/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.7,3.8,-0.1,3.4,5.4,1.088235294,0.685185185,1.117647059,0.703703704,,4.4,N,N,,,120,NORMAL,3.7,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 6,6,41,3/6/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,108,NORMAL,10.26,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 6,6,41,3/6/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,51,8,31,110,1.903225806,0.536363636,1.64516129,0.463636364,,106,N,N,,,104,NORMAL,59,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 6,6,41,3/6/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,21,1,6,34,3.666666667,0.647058824,3.5,0.617647059,,29,N,N,,,105,NORMAL,22,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 6,6,41,3/6/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,25,2,9,34,3,0.794117647,2.777777778,0.735294118,,24,N,N,,,106,NORMAL,27,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 8,8,56,3/21/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.8,3.8,0,3.4,5.4,1.117647059,0.703703704,1.117647059,0.703703704,,4.3,N,N,,,150,NORMAL,3.8,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 8,8,56,3/21/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,138,NORMAL,10.26,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 8,8,56,3/21/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,51,0,31,110,1.64516129,0.463636364,1.64516129,0.463636364,Y,114,N,N,,,134,NORMAL,51,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 8,8,56,3/21/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,21,3,6,34,4,0.705882353,3.5,0.617647059,,27,N,N,,,135,NORMAL,24,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 8,8,56,3/21/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,9,34,3.333333333,0.882352941,2.777777778,0.735294118,,25.5,N,N,,,136,NORMAL,30,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 12,12,83,4/17/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.5,3.8,-0.3,3.4,5.4,1.029411765,0.648148148,1.117647059,0.703703704,Y,4.6,N,N,,,181,NORMAL,3.5,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 12,12,83,4/17/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,168,NORMAL,10.26,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 12,12,83,4/17/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,51,1,31,110,1.677419355,0.472727273,1.64516129,0.463636364,,113,N,N,,,164,NORMAL,52,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 12,12,83,4/17/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,21,6,6,34,4.5,0.794117647,3.5,0.617647059,,24,N,N,,,165,NORMAL,27,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 12,12,83,4/17/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,9,34,3.333333333,0.882352941,2.777777778,0.735294118,,25.5,N,N,,,166,NORMAL,30,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 16,16,111,5/15/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,3.7,3.8,-0.1,3.4,5.4,1.088235294,0.685185185,1.117647059,0.703703704,,4.4,N,N,,,216,NORMAL,3.7,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 16,16,111,5/15/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,17.1,8.55,8.55,3,21,5.7,0.814285714,2.85,0.407142857,,15.6,N,N,,,204,NORMAL,17.1,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 16,16,111,5/15/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,51,11,31,110,2,0.563636364,1.64516129,0.463636364,,103,N,N,,,199,NORMAL,62,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 16,16,111,5/15/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,0,6,34,3.5,0.617647059,3.5,0.617647059,Y,30,N,N,,,200,NORMAL,21,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 16,16,111,5/15/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,0,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,,,202,NORMAL,25,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 20,20,139,6/12/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.8,3.8,0,3.4,5.4,1.117647059,0.703703704,1.117647059,0.703703704,,4.3,N,N,,,246,NORMAL,3.8,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 20,20,139,6/12/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,13.68,8.55,5.13,3,21,4.56,0.651428571,2.85,0.407142857,,17.82,N,N,,,234,NORMAL,13.68,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 20,20,139,6/12/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,51,15,31,110,2.129032258,0.6,1.64516129,0.463636364,,99,N,N,,,230,NORMAL,66,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 20,20,139,6/12/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,21,1,6,34,3.666666667,0.647058824,3.5,0.617647059,,29,N,N,,,231,NORMAL,22,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 20,20,139,6/12/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,9,34,3.333333333,0.882352941,2.777777778,0.735294118,,25.5,N,N,,,232,NORMAL,30,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 24,24,169,7/12/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.7,3.8,-0.1,3.4,5.4,1.088235294,0.685185185,1.117647059,0.703703704,,4.4,N,N,,Y,277,NORMAL,3.7,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,169,7/12/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.7,3.8,-0.1,3.4,5.4,1.088235294,0.685185185,1.117647059,0.703703704,,4.4,N,N,,Y,277,NORMAL,3.7,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 24,24,169,7/12/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,264,NORMAL,10.26,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,169,7/12/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,264,NORMAL,10.26,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 24,24,169,7/12/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,51,7,31,110,1.870967742,0.527272727,1.64516129,0.463636364,,107,N,N,,Y,260,NORMAL,58,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,169,7/12/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,51,7,31,110,1.870967742,0.527272727,1.64516129,0.463636364,,107,N,N,,Y,260,NORMAL,58,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 24,24,169,7/12/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,0,6,34,3.5,0.617647059,3.5,0.617647059,,30,N,N,,Y,261,NORMAL,21,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,169,7/12/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,0,6,34,3.5,0.617647059,3.5,0.617647059,,30,N,N,,Y,261,NORMAL,21,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 24,24,169,7/12/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,0,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,,Y,262,NORMAL,25,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,169,7/12/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,0,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,,Y,262,NORMAL,25,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 26,26,183,7/26/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,3.7,3.8,-0.1,3.4,5.4,1.088235294,0.685185185,1.117647059,0.703703704,,4.4,N,N,,,313,NORMAL,3.7,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 26,26,183,7/26/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,18.81,8.55,10.26,3,21,6.27,0.895714286,2.85,0.407142857,,17.31,N,N,,,301,NORMAL,18.81,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 26,26,183,7/26/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,51,15,31,110,2.129032258,0.6,1.64516129,0.463636364,,99,N,N,,,296,NORMAL,66,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 26,26,183,7/26/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,21,2,6,34,3.833333333,0.676470588,3.5,0.617647059,,28,N,N,,,297,NORMAL,23,0,No
CDISCPILOT01,1287,01-701-1287,Xanomeline High Dose,81,Xanomeline High Dose,81,1/25/14,7/26/14,56,<65,1,WHITE,1,F,Y,,Y, Week 26,26,183,7/26/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,25,2,9,34,3,0.794117647,2.777777778,0.735294118,,24,N,N,,,299,NORMAL,27,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,3/17/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.8,4.8,,3.4,5.4,1.411764706,0.888888889,1.411764706,0.888888889,,3.3,N,N,Y,,19,NORMAL,4.8,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,3/17/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,3/17/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,88,,35,115,2.514285714,0.765217391,2.514285714,0.765217391,,84.5,N,N,Y,,2,NORMAL,88,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,3/17/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,20,,6,43,3.333333333,0.465116279,3.333333333,0.465116279,,44.5,N,N,Y,,3,NORMAL,20,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,3/17/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,,11,36,2.090909091,0.638888889,2.090909091,0.638888889,,31,N,N,Y,,4,NORMAL,23,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,18,4/10/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.8,-0.2,3.4,5.4,1.352941176,0.851851852,1.411764706,0.888888889,,3.5,N,N,,,56,NORMAL,4.6,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,18,4/10/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,18,4/10/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,88,10,35,115,2.8,0.852173913,2.514285714,0.765217391,,80.5,N,N,,,39,NORMAL,98,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,18,4/10/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,20,2,6,43,3.666666667,0.511627907,3.333333333,0.465116279,Y,42.5,N,N,,,40,NORMAL,22,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,18,4/10/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,23,3,11,36,2.363636364,0.722222222,2.090909091,0.638888889,Y,28,N,N,,,41,NORMAL,26,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,32,4/24/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.9,4.8,0.1,3.4,5.4,1.441176471,0.907407407,1.411764706,0.888888889,,3.2,N,N,,,90,NORMAL,4.9,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,32,4/24/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,32,4/24/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,100,88,12,35,115,2.857142857,0.869565217,2.514285714,0.765217391,,82.5,N,N,,,74,NORMAL,100,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,32,4/24/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,20,9,6,43,4.833333333,0.674418605,3.333333333,0.465116279,,35.5,N,N,,,75,NORMAL,29,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,32,4/24/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,23,4,11,36,2.454545455,0.75,2.090909091,0.638888889,,27,N,N,,,76,NORMAL,27,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,46,5/8/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.8,-0.4,3.4,5.4,1.294117647,0.814814815,1.411764706,0.888888889,Y,3.7,N,N,,,120,NORMAL,4.4,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,46,5/8/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,108,NORMAL,10.26,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,46,5/8/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,88,0,35,115,2.514285714,0.765217391,2.514285714,0.765217391,Y,84.5,N,N,,,104,NORMAL,88,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,46,5/8/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,28,20,8,6,43,4.666666667,0.651162791,3.333333333,0.465116279,,36.5,N,N,,,105,NORMAL,28,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,46,5/8/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,23,5,11,36,2.545454545,0.777777778,2.090909091,0.638888889,,26,N,N,,,106,NORMAL,28,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,60,5/22/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,5.1,4.8,0.3,3.4,5.4,1.5,0.944444444,1.411764706,0.888888889,,3.4,N,N,,,150,NORMAL,5.1,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,60,5/22/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,60,5/22/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,88,10,35,115,2.8,0.852173913,2.514285714,0.765217391,,80.5,N,N,,,134,NORMAL,98,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,60,5/22/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,28,20,8,6,43,4.666666667,0.651162791,3.333333333,0.465116279,,36.5,N,N,,,135,NORMAL,28,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,60,5/22/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,23,5,11,36,2.545454545,0.777777778,2.090909091,0.638888889,,26,N,N,,,136,NORMAL,28,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,83,6/14/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,5.1,4.8,0.3,3.4,5.4,1.5,0.944444444,1.411764706,0.888888889,,3.4,N,N,,Y,181,NORMAL,5.1,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,83,6/14/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,5.1,4.8,0.3,3.4,5.4,1.5,0.944444444,1.411764706,0.888888889,,3.4,N,N,,Y,181,NORMAL,5.1,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,83,6/14/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,Y,168,NORMAL,6.84,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,83,6/14/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,Y,168,NORMAL,6.84,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,83,6/14/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,88,1,35,115,2.542857143,0.773913043,2.514285714,0.765217391,,83.5,N,N,,Y,164,NORMAL,89,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,83,6/14/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,88,1,35,115,2.542857143,0.773913043,2.514285714,0.765217391,,83.5,N,N,,Y,164,NORMAL,89,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,83,6/14/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,20,7,6,43,4.5,0.627906977,3.333333333,0.465116279,,37.5,N,N,,Y,165,NORMAL,27,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,83,6/14/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,20,7,6,43,4.5,0.627906977,3.333333333,0.465116279,,37.5,N,N,,Y,165,NORMAL,27,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,83,6/14/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,23,5,11,36,2.545454545,0.777777778,2.090909091,0.638888889,,26,N,N,,Y,166,NORMAL,28,0,No
CDISCPILOT01,1294,01-701-1294,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/24/13,6/14/13,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,83,6/14/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,23,5,11,36,2.545454545,0.777777778,2.090909091,0.638888889,,26,N,N,,Y,166,NORMAL,28,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-9,8/20/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-9,8/20/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-9,8/20/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,67,,35,115,1.914285714,0.582608696,1.914285714,0.582608696,,105.5,N,N,Y,,2,NORMAL,67,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-9,8/20/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,62,62,,6,43,10.33333333,1.441860465,10.33333333,1.441860465,,59,N,N,Y,,3,HIGH,62,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-9,8/20/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,52,52,,11,36,4.727272727,1.444444444,4.727272727,1.444444444,,46.5,N,N,Y,,4,HIGH,52,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,18,9/15/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.8,4.3,-0.5,3.4,5.4,1.117647059,0.703703704,1.264705882,0.796296296,Y,4.3,N,N,,,56,NORMAL,3.8,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,18,9/15/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,Y,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,18,9/15/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,67,-6,35,115,1.742857143,0.530434783,1.914285714,0.582608696,Y,111.5,N,N,,,39,NORMAL,61,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,18,9/15/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,31,62,-31,6,43,5.166666667,0.720930233,10.33333333,1.441860465,,33.5,N,N,,,40,NORMAL,31,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,18,9/15/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,52,-22,11,36,2.727272727,0.833333333,4.727272727,1.444444444,,24.5,N,N,,,41,NORMAL,30,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,9/24/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,,90,NORMAL,4.1,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,9/24/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,9/24/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,67,8,35,115,2.142857143,0.652173913,1.914285714,0.582608696,,97.5,N,N,,,74,NORMAL,75,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,9/24/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,34,62,-28,6,43,5.666666667,0.790697674,10.33333333,1.441860465,,31,N,N,,,75,NORMAL,34,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,9/24/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,52,-22,11,36,2.727272727,0.833333333,4.727272727,1.444444444,,24.5,N,N,,,76,NORMAL,30,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,41,10/8/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,,4.2,N,N,,,120,NORMAL,3.9,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,41,10/8/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,108,NORMAL,10.26,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,41,10/8/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,67,10,35,115,2.2,0.669565217,1.914285714,0.582608696,,95.5,N,N,,,104,NORMAL,77,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,41,10/8/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,52,62,-10,6,43,8.666666667,1.209302326,10.33333333,1.441860465,Y,49,N,N,,,105,HIGH,52,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,41,10/8/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,73,52,21,11,36,6.636363636,2.027777778,4.727272727,1.444444444,Y,67.5,H,N,,,106,HIGH,73,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 8,8,55,10/22/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,150,NORMAL,4.3,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 8,8,55,10/22/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 8,8,55,10/22/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,67,-5,35,115,1.771428571,0.539130435,1.914285714,0.582608696,,110.5,N,N,,,134,NORMAL,62,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 8,8,55,10/22/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,62,-29,6,43,5.5,0.76744186,10.33333333,1.441860465,,31.5,N,N,,,135,NORMAL,33,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 8,8,55,10/22/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,52,-22,11,36,2.727272727,0.833333333,4.727272727,1.444444444,,24.5,N,N,,,136,NORMAL,30,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 12,12,69,11/5/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,Y,181,NORMAL,4.1,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,69,11/5/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,Y,181,NORMAL,4.1,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 12,12,69,11/5/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,Y,168,NORMAL,8.55,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,69,11/5/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,Y,168,NORMAL,8.55,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 12,12,69,11/5/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,67,-5,35,115,1.771428571,0.539130435,1.914285714,0.582608696,,110.5,N,N,,Y,164,NORMAL,62,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,69,11/5/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,67,-5,35,115,1.771428571,0.539130435,1.914285714,0.582608696,,110.5,N,N,,Y,164,NORMAL,62,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 12,12,69,11/5/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,62,-38,6,43,4,0.558139535,10.33333333,1.441860465,,40.5,N,N,,Y,165,NORMAL,24,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,69,11/5/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,62,-38,6,43,4,0.558139535,10.33333333,1.441860465,,40.5,N,N,,Y,165,NORMAL,24,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y, Week 12,12,69,11/5/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,52,-27,11,36,2.272727273,0.694444444,4.727272727,1.444444444,,29,N,N,,Y,166,NORMAL,25,0,No
CDISCPILOT01,1302,01-701-1302,Xanomeline High Dose,81,Xanomeline High Dose,81,8/29/13,11/5/13,61,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,69,11/5/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,52,-27,11,36,2.272727273,0.694444444,4.727272727,1.444444444,,29,N,N,,Y,166,NORMAL,25,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, .,,-12,5/10/14,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,27.36,22.23,5.13,3,21,9.12,1.302857143,7.41,1.058571429,,25.86,N,N,,,43,HIGH,27.36,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, .,,-12,5/10/14,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,69,-2,35,115,1.914285714,0.582608696,1.971428571,0.6,,105.5,N,N,,,39,NORMAL,67,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, .,,-12,5/10/14,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,43,1.833333333,0.255813953,1.5,0.209302326,,53.5,N,N,,,40,NORMAL,11,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, .,,-12,5/10/14,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,17,1,11,36,1.636363636,0.5,1.545454545,0.472222222,,36,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,5/13/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,5/13/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,22.23,22.23,,3,21,7.41,1.058571429,7.41,1.058571429,,20.73,N,N,Y,,6,HIGH,22.23,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,5/13/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,69,,35,115,1.971428571,0.6,1.971428571,0.6,,103.5,N,N,Y,,2,NORMAL,69,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,5/13/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,,6,43,1.5,0.209302326,1.5,0.209302326,,55.5,N,N,Y,,3,NORMAL,9,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-9,5/13/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,Y,,4,NORMAL,17,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,6/5/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4,0.6,3.4,5.4,1.352941176,0.851851852,1.176470588,0.740740741,,3.5,N,N,,,87,NORMAL,4.6,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,6/5/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,23.94,22.23,1.71,3,21,7.98,1.14,7.41,1.058571429,,22.44,N,N,,,74,HIGH,23.94,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,6/5/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,69,4,35,115,2.085714286,0.634782609,1.971428571,0.6,,99.5,N,N,,,70,NORMAL,73,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,6/5/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,9,4,6,43,2.166666667,0.302325581,1.5,0.209302326,,51.5,N,N,,,71,NORMAL,13,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,6/5/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,17,2,11,36,1.727272727,0.527777778,1.545454545,0.472222222,,35,N,N,,,72,NORMAL,19,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,6/19/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,,121,NORMAL,4.4,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,6/19/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,22.23,22.23,0,3,21,7.41,1.058571429,7.41,1.058571429,,20.73,N,N,,,109,HIGH,22.23,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,6/19/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,69,-1,35,115,1.942857143,0.591304348,1.971428571,0.6,,104.5,N,N,,,105,NORMAL,68,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,6/19/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,0,6,43,1.5,0.209302326,1.5,0.209302326,,55.5,N,N,,,106,NORMAL,9,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,6/19/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,17,1,11,36,1.636363636,0.5,1.545454545,0.472222222,,36,N,N,,,107,NORMAL,18,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,7/3/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,,151,NORMAL,4.4,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,7/3/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,23.94,22.23,1.71,3,21,7.98,1.14,7.41,1.058571429,,22.44,N,N,,,139,HIGH,23.94,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,7/3/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,71,69,2,35,115,2.028571429,0.617391304,1.971428571,0.6,,101.5,N,N,,,135,NORMAL,71,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,7/3/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,8,9,-1,6,43,1.333333333,0.186046512,1.5,0.209302326,Y,56.5,N,N,,,136,NORMAL,8,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,7/3/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,0,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,,,137,NORMAL,17,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,62,7/22/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.2,4,0.2,3.4,5.4,1.235294118,0.777777778,1.176470588,0.740740741,,3.9,N,N,,,181,NORMAL,4.2,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,62,7/22/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,25.65,22.23,3.42,3,21,8.55,1.221428571,7.41,1.058571429,Y,24.15,N,N,,,169,HIGH,25.65,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,62,7/22/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,69,5,35,115,2.114285714,0.643478261,1.971428571,0.6,,98.5,N,N,,,165,NORMAL,74,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,62,7/22/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,43,1.833333333,0.255813953,1.5,0.209302326,,53.5,N,N,,,166,NORMAL,11,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,62,7/22/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,17,-2,11,36,1.363636364,0.416666667,1.545454545,0.472222222,,39,N,N,,,167,NORMAL,15,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,86,8/15/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,4,-0.1,3.4,5.4,1.147058824,0.722222222,1.176470588,0.740740741,Y,4.2,N,N,,,212,NORMAL,3.9,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,86,8/15/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,23.94,22.23,1.71,3,21,7.98,1.14,7.41,1.058571429,,22.44,N,N,,,199,HIGH,23.94,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,86,8/15/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,69,-11,35,115,1.657142857,0.504347826,1.971428571,0.6,Y,114.5,N,N,,,195,NORMAL,58,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,86,8/15/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,0,6,43,1.5,0.209302326,1.5,0.209302326,,55.5,N,N,,,196,NORMAL,9,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,86,8/15/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,17,-3,11,36,1.272727273,0.388888889,1.545454545,0.472222222,,40,N,N,,,197,NORMAL,14,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,9/11/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,246,NORMAL,4.1,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,9/11/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,23.94,22.23,1.71,3,21,7.98,1.14,7.41,1.058571429,,22.44,N,N,,,234,HIGH,23.94,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,9/11/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,69,-4,35,115,1.857142857,0.565217391,1.971428571,0.6,,107.5,N,N,,,230,NORMAL,65,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,9/11/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,43,1.833333333,0.255813953,1.5,0.209302326,,53.5,N,N,,,231,NORMAL,11,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,9/11/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,0,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,,,232,NORMAL,17,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,10/9/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.3,4,0.3,3.4,5.4,1.264705882,0.796296296,1.176470588,0.740740741,,3.8,N,N,,,276,NORMAL,4.3,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,10/9/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,20.52,22.23,-1.71,3,21,6.84,0.977142857,7.41,1.058571429,,19.02,N,N,,,264,NORMAL,20.52,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,10/9/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,69,0,35,115,1.971428571,0.6,1.971428571,0.6,,103.5,N,N,,,260,NORMAL,69,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,10/9/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,43,1.833333333,0.255813953,1.5,0.209302326,,53.5,N,N,,,261,NORMAL,11,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,10/9/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,0,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,,,262,NORMAL,17,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,11/6/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,Y,307,NORMAL,4,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,11/6/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,Y,307,NORMAL,4,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,11/6/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,22.23,22.23,0,3,21,7.41,1.058571429,7.41,1.058571429,,20.73,N,N,,Y,294,HIGH,22.23,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,11/6/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,22.23,22.23,0,3,21,7.41,1.058571429,7.41,1.058571429,,20.73,N,N,,Y,294,HIGH,22.23,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,11/6/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,69,6,35,115,2.142857143,0.652173913,1.971428571,0.6,,97.5,N,N,,Y,290,NORMAL,75,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,11/6/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,69,6,35,115,2.142857143,0.652173913,1.971428571,0.6,,97.5,N,N,,Y,290,NORMAL,75,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,11/6/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,9,1,6,43,1.666666667,0.23255814,1.5,0.209302326,,54.5,N,N,,Y,291,NORMAL,10,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,11/6/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,9,1,6,43,1.666666667,0.23255814,1.5,0.209302326,,54.5,N,N,,Y,291,NORMAL,10,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,11/6/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,11,17,-6,11,36,1,0.305555556,1.545454545,0.472222222,Y,43,N,N,,Y,292,NORMAL,11,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,11/6/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,11,17,-6,11,36,1,0.305555556,1.545454545,0.472222222,Y,43,N,N,,Y,292,NORMAL,11,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,11/20/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,341,NORMAL,4.1,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,11/20/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,32.49,22.23,10.26,3,21,10.83,1.547142857,7.41,1.058571429,,30.99,H,N,,,329,HIGH,32.49,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,11/20/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,69,6,35,115,2.142857143,0.652173913,1.971428571,0.6,,97.5,N,N,,,325,NORMAL,75,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,11/20/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,9,5,6,43,2.333333333,0.325581395,1.5,0.209302326,,50.5,N,N,,,326,NORMAL,14,0,No
CDISCPILOT01,1317,01-701-1317,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/22/14,11/20/14,68,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,11/20/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,17,2,11,36,1.727272727,0.527777778,1.545454545,0.472222222,,35,N,N,,,327,NORMAL,19,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/16/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.7,4.7,,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,Y,,19,NORMAL,4.7,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/16/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/16/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,84,,35,115,2.4,0.730434783,2.4,0.730434783,,88.5,N,N,Y,,2,NORMAL,84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/16/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,11,,6,35,1.833333333,0.314285714,1.833333333,0.314285714,,41.5,N,N,Y,,3,NORMAL,11,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/16/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,11,36,1.818181818,0.555555556,1.818181818,0.555555556,,34,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, .,,24,10/25/12,UNSCHEDULED 4.1,4.1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,54,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, .,,24,10/25/12,UNSCHEDULED 4.1,4.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,84,11,35,115,2.714285714,0.826086957,2.4,0.730434783,,77.5,N,N,,,50,NORMAL,95,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, .,,24,10/25/12,UNSCHEDULED 4.1,4.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,11,-1,6,35,1.666666667,0.285714286,1.833333333,0.314285714,,42.5,N,N,,,51,NORMAL,10,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, .,,24,10/25/12,UNSCHEDULED 4.1,4.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,11,36,1.727272727,0.527777778,1.818181818,0.555555556,,35,N,N,,,52,NORMAL,19,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,10/30/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.9,4.7,0.2,3.4,5.4,1.441176471,0.907407407,1.382352941,0.87037037,,3.2,N,N,,,99,NORMAL,4.9,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,10/30/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,87,NORMAL,8.55,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,10/30/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,84,-4,35,115,2.285714286,0.695652174,2.4,0.730434783,Y,92.5,N,N,,,83,NORMAL,80,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,10/30/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,11,-1,6,35,1.666666667,0.285714286,1.833333333,0.314285714,,42.5,N,N,,,84,NORMAL,10,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,29,10/30/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,11,36,1.636363636,0.5,1.818181818,0.555555556,,36,N,N,,,85,NORMAL,18,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,11/13/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,,129,NORMAL,4.6,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,11/13/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,117,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,11/13/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,84,-4,35,115,2.285714286,0.695652174,2.4,0.730434783,,92.5,N,N,,,113,NORMAL,80,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,11/13/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,8,11,-3,6,35,1.333333333,0.228571429,1.833333333,0.314285714,,44.5,N,N,,,114,NORMAL,8,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,11/13/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,11,36,1.636363636,0.5,1.818181818,0.555555556,,36,N,N,,,115,NORMAL,18,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,55,11/25/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.9,4.7,0.2,3.4,5.4,1.441176471,0.907407407,1.382352941,0.87037037,,3.2,N,N,,,159,NORMAL,4.9,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,55,11/25/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,147,NORMAL,8.55,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,55,11/25/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,84,9,35,115,2.657142857,0.808695652,2.4,0.730434783,,79.5,N,N,,,143,NORMAL,93,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,55,11/25/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,11,4,6,35,2.5,0.428571429,1.833333333,0.314285714,,37.5,N,N,,,144,NORMAL,15,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,55,11/25/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,11,36,1.727272727,0.527777778,1.818181818,0.555555556,,35,N,N,,,145,NORMAL,19,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,12/25/12,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.8,4.7,0.1,3.4,5.4,1.411764706,0.888888889,1.382352941,0.87037037,,3.3,N,N,,,190,NORMAL,4.8,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,12/25/12,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,177,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,12/25/12,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,84,11,35,115,2.714285714,0.826086957,2.4,0.730434783,,77.5,N,N,,,173,NORMAL,95,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,12/25/12,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,11,1,6,35,2,0.342857143,1.833333333,0.314285714,,40.5,N,N,,,174,NORMAL,12,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,12/25/12,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,20,1,11,36,1.909090909,0.583333333,1.818181818,0.555555556,,33,N,N,,,175,NORMAL,21,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,1/22/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,4.7,-0.3,3.4,5.4,1.294117647,0.814814815,1.382352941,0.87037037,Y,3.7,N,N,,,224,NORMAL,4.4,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,1/22/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,Y,26.37,N,N,,,212,NORMAL,5.13,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,1/22/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,84,4,35,115,2.514285714,0.765217391,2.4,0.730434783,,84.5,N,N,,,208,NORMAL,88,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,1/22/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,11,0,6,35,1.833333333,0.314285714,1.833333333,0.314285714,,41.5,N,N,,,209,NORMAL,11,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,1/22/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,11,36,1.545454545,0.472222222,1.818181818,0.555555556,,37,N,N,,,210,NORMAL,17,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,2/19/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.7,4.7,0,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,,,254,NORMAL,4.7,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,2/19/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,,26.37,N,N,,,242,NORMAL,5.13,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,2/19/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,84,4,35,115,2.514285714,0.765217391,2.4,0.730434783,,84.5,N,N,,,238,NORMAL,88,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,2/19/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,11,1,6,35,2,0.342857143,1.833333333,0.314285714,,40.5,N,N,,,239,NORMAL,12,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,2/19/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,11,36,1.727272727,0.527777778,1.818181818,0.555555556,,35,N,N,,,240,NORMAL,19,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,3/19/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,Y,285,NORMAL,4.6,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/19/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,Y,285,NORMAL,4.6,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,3/19/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,Y,272,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/19/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,Y,272,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,3/19/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,84,-3,35,115,2.314285714,0.704347826,2.4,0.730434783,,91.5,N,N,,Y,268,NORMAL,81,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/19/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,84,-3,35,115,2.314285714,0.704347826,2.4,0.730434783,,91.5,N,N,,Y,268,NORMAL,81,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,3/19/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,11,-4,6,35,1.166666667,0.2,1.833333333,0.314285714,Y,45.5,N,N,,Y,269,NORMAL,7,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/19/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,11,-4,6,35,1.166666667,0.2,1.833333333,0.314285714,Y,45.5,N,N,,Y,269,NORMAL,7,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,169,3/19/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,20,-6,11,36,1.272727273,0.388888889,1.818181818,0.555555556,Y,40,N,N,,Y,270,NORMAL,14,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/19/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,20,-6,11,36,1.272727273,0.388888889,1.818181818,0.555555556,Y,40,N,N,,Y,270,NORMAL,14,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/2/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.4,4.7,-0.3,3.4,5.4,1.294117647,0.814814815,1.382352941,0.87037037,,3.7,N,N,,,319,NORMAL,4.4,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/2/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,307,NORMAL,6.84,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/2/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,85,84,1,35,115,2.428571429,0.739130435,2.4,0.730434783,,87.5,N,N,,,303,NORMAL,85,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/2/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,11,-4,6,35,1.166666667,0.2,1.833333333,0.314285714,,45.5,N,N,,,304,NORMAL,7,0,No
CDISCPILOT01,1324,01-701-1324,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/2/12,4/2/13,79,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/2/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,11,36,1.545454545,0.472222222,1.818181818,0.555555556,,37,N,N,,,305,NORMAL,17,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,12/22/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,12/22/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,12/22/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,52,,31,110,1.677419355,0.472727273,1.677419355,0.472727273,,113,N,N,Y,,2,NORMAL,52,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,12/22/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,58,58,,6,43,9.666666667,1.348837209,9.666666667,1.348837209,,55,N,N,Y,,3,HIGH,58,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-14,12/22/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,53,53,,11,36,4.818181818,1.472222222,4.818181818,1.472222222,,47.5,N,N,Y,,4,HIGH,53,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, .,,-10,12/26/12,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,,26.37,N,N,,,42,NORMAL,5.13,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, .,,-10,12/26/12,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,52,-6,31,110,1.483870968,0.418181818,1.677419355,0.472727273,,119,N,N,,,39,NORMAL,46,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, .,,-10,12/26/12,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,43,58,-15,6,43,7.166666667,1,9.666666667,1.348837209,,40,N,N,,,40,NORMAL,43,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, .,,-10,12/26/12,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,51,53,-2,11,36,4.636363636,1.416666667,4.818181818,1.472222222,,45.5,N,N,,,41,HIGH,51,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.1,0.3,3.4,5.4,1.294117647,0.814814815,1.205882353,0.759259259,,3.7,N,N,,,72,NORMAL,4.4,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,59,NORMAL,8.55,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,52,-2,31,110,1.612903226,0.454545455,1.677419355,0.472727273,Y,115,N,N,,,55,NORMAL,50,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,58,-43,6,43,2.5,0.348837209,9.666666667,1.348837209,Y,49.5,N,N,,,56,NORMAL,15,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,53,-32,11,36,1.909090909,0.583333333,4.818181818,1.472222222,Y,33,N,N,,,57,NORMAL,21,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,34,2/7/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.1,0.2,3.4,5.4,1.264705882,0.796296296,1.205882353,0.759259259,Y,3.8,N,N,,Y,107,NORMAL,4.3,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,34,2/7/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.1,0.2,3.4,5.4,1.264705882,0.796296296,1.205882353,0.759259259,Y,3.8,N,N,,Y,107,NORMAL,4.3,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,34,2/7/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,94,NORMAL,6.84,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,34,2/7/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,94,NORMAL,6.84,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,34,2/7/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,52,9,31,110,1.967741935,0.554545455,1.677419355,0.472727273,,104,N,N,,Y,90,NORMAL,61,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,34,2/7/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,52,9,31,110,1.967741935,0.554545455,1.677419355,0.472727273,,104,N,N,,Y,90,NORMAL,61,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,34,2/7/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,58,-31,6,43,4.5,0.627906977,9.666666667,1.348837209,,37.5,N,N,,Y,91,NORMAL,27,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,34,2/7/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,58,-31,6,43,4.5,0.627906977,9.666666667,1.348837209,,37.5,N,N,,Y,91,NORMAL,27,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,34,2/7/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,34,53,-19,11,36,3.090909091,0.944444444,4.818181818,1.472222222,,28.5,N,N,,Y,92,NORMAL,34,0,No
CDISCPILOT01,1341,01-701-1341,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/5/13,1/26/13,51,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,34,2/7/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,34,53,-19,11,36,3.090909091,0.944444444,4.818181818,1.472222222,,28.5,N,N,,Y,92,NORMAL,34,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,10/1/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.6,3.6,,3.4,5.4,1.058823529,0.666666667,1.058823529,0.666666667,,4.5,N,N,Y,,19,NORMAL,3.6,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,10/1/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,10/1/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,60,,35,115,1.714285714,0.52173913,1.714285714,0.52173913,,112.5,N,N,Y,,2,NORMAL,60,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,10/1/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,,6,34,2.166666667,0.382352941,2.166666667,0.382352941,,38,N,N,Y,,3,NORMAL,13,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Baseline,0,-7,10/1/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,22,,9,34,2.444444444,0.647058824,2.444444444,0.647058824,,29,N,N,Y,,4,NORMAL,22,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,17,10/24/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,3.6,0.8,3.4,5.4,1.294117647,0.814814815,1.058823529,0.666666667,,3.7,N,N,,,56,NORMAL,4.4,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,17,10/24/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,17,10/24/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,60,1,35,115,1.742857143,0.530434783,1.714285714,0.52173913,,111.5,N,N,,,39,NORMAL,61,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,17,10/24/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,13,-4,6,34,1.5,0.264705882,2.166666667,0.382352941,,42,N,N,,,40,NORMAL,9,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 2,2,17,10/24/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,22,-4,9,34,2,0.529411765,2.444444444,0.647058824,,33,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,32,11/8/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,3.6,1.1,3.4,5.4,1.382352941,0.87037037,1.058823529,0.666666667,,3.4,N,N,,,90,NORMAL,4.7,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,32,11/8/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,32,11/8/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,60,9,35,115,1.971428571,0.6,1.714285714,0.52173913,,103.5,N,N,,,74,NORMAL,69,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,32,11/8/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,13,-2,6,34,1.833333333,0.323529412,2.166666667,0.382352941,,40,N,N,,,75,NORMAL,11,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 4,4,32,11/8/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,22,3,9,34,2.777777778,0.735294118,2.444444444,0.647058824,,26,N,N,,,76,NORMAL,25,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,43,11/19/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,3.6,0.8,3.4,5.4,1.294117647,0.814814815,1.058823529,0.666666667,,3.7,N,N,,,120,NORMAL,4.4,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,43,11/19/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,108,NORMAL,6.84,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,43,11/19/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,60,5,35,115,1.857142857,0.565217391,1.714285714,0.52173913,,107.5,N,N,,,104,NORMAL,65,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,43,11/19/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,13,-3,6,34,1.666666667,0.294117647,2.166666667,0.382352941,,41,N,N,,,105,NORMAL,10,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 6,6,43,11/19/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,22,0,9,34,2.444444444,0.647058824,2.444444444,0.647058824,,29,N,N,,,106,NORMAL,22,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,57,12/3/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.6,3.6,1,3.4,5.4,1.352941176,0.851851852,1.058823529,0.666666667,,3.5,N,N,,,150,NORMAL,4.6,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,57,12/3/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,Y,26.37,N,N,,,138,NORMAL,5.13,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,57,12/3/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,60,2,35,115,1.771428571,0.539130435,1.714285714,0.52173913,,110.5,N,N,,,134,NORMAL,62,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,57,12/3/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,13,-6,6,34,1.166666667,0.205882353,2.166666667,0.382352941,Y,44,N,N,,,135,NORMAL,7,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 8,8,57,12/3/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,22,-6,9,34,1.777777778,0.470588235,2.444444444,0.647058824,,35,N,N,,,136,NORMAL,16,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,85,12/31/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,3.6,0.5,3.4,5.4,1.205882353,0.759259259,1.058823529,0.666666667,Y,4,N,N,,,181,NORMAL,4.1,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,85,12/31/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,168,NORMAL,8.55,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,85,12/31/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,60,-3,35,115,1.628571429,0.495652174,1.714285714,0.52173913,,115.5,N,N,,,164,NORMAL,57,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,85,12/31/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,34,2.333333333,0.411764706,2.166666667,0.382352941,,37,N,N,,,165,NORMAL,14,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 12,12,85,12/31/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,22,0,9,34,2.444444444,0.647058824,2.444444444,0.647058824,,29,N,N,,,166,NORMAL,22,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,112,1/27/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,3.6,0.8,3.4,5.4,1.294117647,0.814814815,1.058823529,0.666666667,,3.7,N,N,,,215,NORMAL,4.4,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,112,1/27/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,203,NORMAL,8.55,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,112,1/27/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,60,-1,35,115,1.685714286,0.513043478,1.714285714,0.52173913,,113.5,N,N,,,199,NORMAL,59,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,112,1/27/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,34,2.166666667,0.382352941,2.166666667,0.382352941,,38,N,N,,,200,NORMAL,13,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 16,16,112,1/27/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,22,2,9,34,2.666666667,0.705882353,2.444444444,0.647058824,,27,N,N,,,201,NORMAL,24,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,141,2/25/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.8,3.6,1.2,3.4,5.4,1.411764706,0.888888889,1.058823529,0.666666667,,3.3,N,N,,,245,NORMAL,4.8,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,141,2/25/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,233,NORMAL,6.84,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,141,2/25/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,60,-4,35,115,1.6,0.486956522,1.714285714,0.52173913,Y,116.5,N,N,,,229,NORMAL,56,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,141,2/25/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,34,2.166666667,0.382352941,2.166666667,0.382352941,,38,N,N,,,230,NORMAL,13,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 20,20,141,2/25/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,22,0,9,34,2.444444444,0.647058824,2.444444444,0.647058824,,29,N,N,,,231,NORMAL,22,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,162,3/18/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.9,3.6,1.3,3.4,5.4,1.441176471,0.907407407,1.058823529,0.666666667,,3.2,N,N,,Y,276,NORMAL,4.9,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,162,3/18/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.9,3.6,1.3,3.4,5.4,1.441176471,0.907407407,1.058823529,0.666666667,,3.2,N,N,,Y,276,NORMAL,4.9,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,162,3/18/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,162,3/18/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,162,3/18/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,60,-2,35,115,1.657142857,0.504347826,1.714285714,0.52173913,,114.5,N,N,,Y,259,NORMAL,58,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,162,3/18/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,60,-2,35,115,1.657142857,0.504347826,1.714285714,0.52173913,,114.5,N,N,,Y,259,NORMAL,58,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,162,3/18/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,13,12,6,34,4.166666667,0.735294118,2.166666667,0.382352941,,26,N,N,,Y,260,NORMAL,25,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,162,3/18/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,13,12,6,34,4.166666667,0.735294118,2.166666667,0.382352941,,26,N,N,,Y,260,NORMAL,25,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y, Week 24,24,162,3/18/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,46,22,24,9,34,5.111111111,1.352941176,2.444444444,0.647058824,Y,41.5,N,N,,Y,261,HIGH,46,0,No
CDISCPILOT01,1345,01-701-1345,Placebo,0,Placebo,0,10/8/13,3/18/14,63,<65,1,WHITE,1,F,Y,,Y,End of Treatment,99,162,3/18/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,46,22,24,9,34,5.111111111,1.352941176,2.444444444,0.647058824,Y,41.5,N,N,,Y,261,HIGH,46,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-7,7/24/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.9,4.9,,3.4,5.4,1.441176471,0.907407407,1.441176471,0.907407407,,3.2,N,N,Y,,19,NORMAL,4.9,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-7,7/24/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,17.1,17.1,,3,21,5.7,0.814285714,5.7,0.814285714,,15.6,N,N,Y,,6,NORMAL,17.1,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-7,7/24/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,78,,35,115,2.228571429,0.67826087,2.228571429,0.67826087,,94.5,N,N,Y,,2,NORMAL,78,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-7,7/24/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,43,2.666666667,0.372093023,2.666666667,0.372093023,,48.5,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-7,7/24/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,14,,11,36,1.272727273,0.388888889,1.272727273,0.388888889,,40,N,N,Y,,4,NORMAL,14,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,8/14/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.9,-0.3,3.4,5.4,1.352941176,0.851851852,1.441176471,0.907407407,Y,3.5,N,N,,Y,56,NORMAL,4.6,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,15,8/14/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.9,-0.3,3.4,5.4,1.352941176,0.851851852,1.441176471,0.907407407,Y,3.5,N,N,,Y,56,NORMAL,4.6,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,8/14/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,13.68,17.1,-3.42,3,21,4.56,0.651428571,5.7,0.814285714,Y,17.82,N,N,,Y,43,NORMAL,13.68,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,15,8/14/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,13.68,17.1,-3.42,3,21,4.56,0.651428571,5.7,0.814285714,Y,17.82,N,N,,Y,43,NORMAL,13.68,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,8/14/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,78,-5,35,115,2.085714286,0.634782609,2.228571429,0.67826087,Y,99.5,N,N,,Y,39,NORMAL,73,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,15,8/14/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,78,-5,35,115,2.085714286,0.634782609,2.228571429,0.67826087,Y,99.5,N,N,,Y,39,NORMAL,73,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,8/14/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,16,3,6,43,3.166666667,0.441860465,2.666666667,0.372093023,Y,45.5,N,N,,Y,40,NORMAL,19,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,15,8/14/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,16,3,6,43,3.166666667,0.441860465,2.666666667,0.372093023,Y,45.5,N,N,,Y,40,NORMAL,19,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y, Week 2,2,15,8/14/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,14,4,11,36,1.636363636,0.5,1.272727273,0.388888889,Y,36,N,N,,Y,41,NORMAL,18,0,No
CDISCPILOT01,1360,01-701-1360,Xanomeline High Dose,81,Xanomeline High Dose,81,7/31/13,8/5/13,67,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,15,8/14/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,14,4,11,36,1.636363636,0.5,1.272727273,0.388888889,Y,36,N,N,,Y,41,NORMAL,18,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,5/20/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,5/20/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,5/20/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,43,43,,35,115,1.228571429,0.373913043,1.228571429,0.373913043,,129.5,N,N,Y,,2,NORMAL,43,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,5/20/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,,6,32,1.5,0.28125,1.5,0.28125,,39,N,N,Y,,3,NORMAL,9,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,5/20/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,14,6/12/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.1,0.3,3.4,5.4,1.294117647,0.814814815,1.205882353,0.759259259,,3.7,N,N,,,56,NORMAL,4.4,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,14,6/12/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,14,6/12/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,43,43,0,35,115,1.228571429,0.373913043,1.228571429,0.373913043,,129.5,N,N,,,39,NORMAL,43,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,14,6/12/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,,40,NORMAL,11,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,14,6/12/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,,28,N,N,,,41,NORMAL,23,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,27,6/25/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.1,0.2,3.4,5.4,1.264705882,0.796296296,1.205882353,0.759259259,,3.8,N,N,,,90,NORMAL,4.3,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,27,6/25/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,27,6/25/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,40,43,-3,35,115,1.142857143,0.347826087,1.228571429,0.373913043,,132.5,N,N,,,74,NORMAL,40,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,27,6/25/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,0,6,32,1.5,0.28125,1.5,0.28125,,39,N,N,,,75,NORMAL,9,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,27,6/25/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,Y,36,N,N,,,76,NORMAL,15,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,42,7/10/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,Y,4,N,N,,,120,NORMAL,4.1,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,42,7/10/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,3.42,8.55,-5.13,3,21,1.14,0.162857143,2.85,0.407142857,Y,28.08,N,N,,,108,NORMAL,3.42,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,42,7/10/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,41,43,-2,35,115,1.171428571,0.356521739,1.228571429,0.373913043,,131.5,N,N,,,104,NORMAL,41,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,42,7/10/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,9,3,6,32,2,0.375,1.5,0.28125,,36,N,N,,,105,NORMAL,12,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,42,7/10/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,106,NORMAL,20,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,56,7/24/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.7,4.1,0.6,3.4,5.4,1.382352941,0.87037037,1.205882353,0.759259259,,3.4,N,N,,,150,NORMAL,4.7,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,56,7/24/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,56,7/24/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,48,43,5,35,115,1.371428571,0.417391304,1.228571429,0.373913043,,124.5,N,N,,,134,NORMAL,48,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,56,7/24/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,,135,NORMAL,11,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,56,7/24/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,136,NORMAL,20,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,84,8/21/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.8,4.1,0.7,3.4,5.4,1.411764706,0.888888889,1.205882353,0.759259259,,3.3,N,N,,,181,NORMAL,4.8,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,84,8/21/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,,168,NORMAL,5.13,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,84,8/21/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,38,43,-5,35,115,1.085714286,0.330434783,1.228571429,0.373913043,,134.5,N,N,,,164,NORMAL,38,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,84,8/21/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,9,4,6,32,2.166666667,0.40625,1.5,0.28125,,35,N,N,,,165,NORMAL,13,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,84,8/21/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,166,NORMAL,20,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,9/18/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.6,4.1,0.5,3.4,5.4,1.352941176,0.851851852,1.205882353,0.759259259,,3.5,N,N,,,215,NORMAL,4.6,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,9/18/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,203,NORMAL,6.84,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,9/18/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,37,43,-6,35,115,1.057142857,0.32173913,1.228571429,0.373913043,Y,135.5,N,N,,,199,NORMAL,37,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,9/18/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,9,5,6,32,2.333333333,0.4375,1.5,0.28125,,34,N,N,,,200,NORMAL,14,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,9/18/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,20,1,9,34,2.333333333,0.617647059,2.222222222,0.588235294,,30,N,N,,,201,NORMAL,21,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,138,10/14/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.9,4.1,0.8,3.4,5.4,1.441176471,0.907407407,1.205882353,0.759259259,,3.2,N,N,,,245,NORMAL,4.9,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,138,10/14/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,3.42,8.55,-5.13,3,21,1.14,0.162857143,2.85,0.407142857,,28.08,N,N,,,233,NORMAL,3.42,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,138,10/14/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,43,3,35,115,1.314285714,0.4,1.228571429,0.373913043,,126.5,N,N,,,229,NORMAL,46,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,138,10/14/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,9,5,6,32,2.333333333,0.4375,1.5,0.28125,,34,N,N,,,230,NORMAL,14,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,138,10/14/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,20,6,9,34,2.888888889,0.764705882,2.222222222,0.588235294,,25,N,N,,,231,NORMAL,26,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,11/13/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.3,4.1,0.2,3.4,5.4,1.264705882,0.796296296,1.205882353,0.759259259,,3.8,N,N,,Y,276,NORMAL,4.3,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,11/13/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.3,4.1,0.2,3.4,5.4,1.264705882,0.796296296,1.205882353,0.759259259,,3.8,N,N,,Y,276,NORMAL,4.3,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,11/13/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,,8.55,,3,21,,,2.85,0.407142857,,,N,N,,Y,263,,,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,11/13/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,,8.55,,3,21,,,2.85,0.407142857,,,N,N,,Y,263,,,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,11/13/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,43,3,35,115,1.314285714,0.4,1.228571429,0.373913043,,126.5,N,N,,Y,259,NORMAL,46,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,11/13/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,43,3,35,115,1.314285714,0.4,1.228571429,0.373913043,,126.5,N,N,,Y,259,NORMAL,46,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,11/13/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,8,9,-1,6,32,1.333333333,0.25,1.5,0.28125,Y,40,N,N,,Y,260,NORMAL,8,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,11/13/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,8,9,-1,6,32,1.333333333,0.25,1.5,0.28125,Y,40,N,N,,Y,260,NORMAL,8,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,11/13/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,Y,261,NORMAL,17,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,11/13/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,Y,261,NORMAL,17,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,182,11/27/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.3,4.1,0.2,3.4,5.4,1.264705882,0.796296296,1.205882353,0.759259259,,3.8,N,N,,,310,NORMAL,4.3,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,182,11/27/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,182,11/27/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,43,8,35,115,1.457142857,0.443478261,1.228571429,0.373913043,,121.5,N,N,,,294,NORMAL,51,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,182,11/27/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,,295,NORMAL,11,0,No
CDISCPILOT01,1363,01-701-1363,Placebo,0,Placebo,0,5/30/13,11/27/13,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,182,11/27/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,20,1,9,34,2.333333333,0.617647059,2.222222222,0.588235294,,30,N,N,,,296,NORMAL,21,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,1/22/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,1/22/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,1/22/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,66,,35,115,1.885714286,0.573913043,1.885714286,0.573913043,,106.5,N,N,Y,,2,NORMAL,66,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,1/22/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,,6,32,2.833333333,0.53125,2.833333333,0.53125,,31,N,N,Y,,3,NORMAL,17,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,1/22/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,2/19/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,4.3,0.5,3.4,5.4,1.411764706,0.888888889,1.264705882,0.796296296,,3.3,N,N,,,56,NORMAL,4.8,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,2/19/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,2/19/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,66,0,35,115,1.885714286,0.573913043,1.885714286,0.573913043,,106.5,N,N,,,39,NORMAL,66,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,2/19/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,0,6,32,2.833333333,0.53125,2.833333333,0.53125,,31,N,N,,,40,NORMAL,17,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,2/19/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,Y,31,N,N,,,41,NORMAL,20,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,37,3/12/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,,90,NORMAL,4.4,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,37,3/12/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,37,3/12/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,66,-5,35,115,1.742857143,0.530434783,1.885714286,0.573913043,,111.5,N,N,,,74,NORMAL,61,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,37,3/12/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,17,-3,6,32,2.333333333,0.4375,2.833333333,0.53125,,34,N,N,,,75,NORMAL,14,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,37,3/12/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,76,NORMAL,20,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,3/19/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,,120,NORMAL,4.5,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,3/19/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,3/19/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,66,-3,35,115,1.8,0.547826087,1.885714286,0.573913043,,109.5,N,N,,,104,NORMAL,63,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,3/19/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,0,6,32,2.833333333,0.53125,2.833333333,0.53125,,31,N,N,,,105,NORMAL,17,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,3/19/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,,28,N,N,,,106,NORMAL,23,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,4/2/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.5,4.3,-0.8,3.4,5.4,1.029411765,0.648148148,1.264705882,0.796296296,Y,4.6,N,N,,,150,NORMAL,3.5,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,4/2/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,Y,26.37,N,N,,,138,NORMAL,5.13,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,4/2/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,66,-10,35,115,1.6,0.486956522,1.885714286,0.573913043,Y,116.5,N,N,,,134,NORMAL,56,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,4/2/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,17,1,6,32,3,0.5625,2.833333333,0.53125,,30,N,N,,,135,NORMAL,18,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,4/2/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,20,5,9,34,2.777777778,0.735294118,2.222222222,0.588235294,,26,N,N,,,136,NORMAL,25,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,86,4/30/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.6,4.3,0.3,3.4,5.4,1.352941176,0.851851852,1.264705882,0.796296296,,3.5,N,N,,,181,NORMAL,4.6,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,86,4/30/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,168,NORMAL,10.26,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,86,4/30/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,66,-9,35,115,1.628571429,0.495652174,1.885714286,0.573913043,,115.5,N,N,,,164,NORMAL,57,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,86,4/30/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,17,-4,6,32,2.166666667,0.40625,2.833333333,0.53125,Y,35,N,N,,,165,NORMAL,13,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,86,4/30/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,166,NORMAL,20,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,116,5/30/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,,3.9,N,N,,,215,NORMAL,4.2,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,116,5/30/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,203,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,116,5/30/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,66,-6,35,115,1.714285714,0.52173913,1.885714286,0.573913043,,112.5,N,N,,,199,NORMAL,60,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,116,5/30/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,17,2,6,32,3.166666667,0.59375,2.833333333,0.53125,,29,N,N,,,200,NORMAL,19,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,116,5/30/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,20,5,9,34,2.777777778,0.735294118,2.222222222,0.588235294,,26,N,N,,,201,NORMAL,25,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,6/25/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,,245,NORMAL,4.5,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,6/25/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,233,NORMAL,6.84,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,6/25/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,66,-2,35,115,1.828571429,0.556521739,1.885714286,0.573913043,,108.5,N,N,,,229,NORMAL,64,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,6/25/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,17,2,6,32,3.166666667,0.59375,2.833333333,0.53125,,29,N,N,,,230,NORMAL,19,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,142,6/25/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,20,1,9,34,2.333333333,0.617647059,2.222222222,0.588235294,,30,N,N,,,231,NORMAL,21,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,177,7/30/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,Y,276,NORMAL,4.4,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,177,7/30/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,Y,276,NORMAL,4.4,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,177,7/30/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,177,7/30/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,177,7/30/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,66,-8,35,115,1.657142857,0.504347826,1.885714286,0.573913043,,114.5,N,N,,Y,259,NORMAL,58,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,177,7/30/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,66,-8,35,115,1.657142857,0.504347826,1.885714286,0.573913043,,114.5,N,N,,Y,259,NORMAL,58,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,177,7/30/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,32,2.5,0.46875,2.833333333,0.53125,,33,N,N,,Y,260,NORMAL,15,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,177,7/30/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,32,2.5,0.46875,2.833333333,0.53125,,33,N,N,,Y,260,NORMAL,15,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,177,7/30/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,177,7/30/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,8/6/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,,310,NORMAL,4.1,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,8/6/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,8/6/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,66,-13,35,115,1.514285714,0.460869565,1.885714286,0.573913043,,119.5,N,N,,,294,NORMAL,53,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,8/6/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,17,-3,6,32,2.333333333,0.4375,2.833333333,0.53125,,34,N,N,,,295,NORMAL,14,0,No
CDISCPILOT01,1383,01-701-1383,Xanomeline High Dose,81,Xanomeline High Dose,81,2/4/13,8/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,8/6/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,296,NORMAL,17,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-17,2/23/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,5.1,5.1,,3.4,5.4,1.5,0.944444444,1.5,0.944444444,,3.4,N,N,Y,,19,NORMAL,5.1,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-17,2/23/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-17,2/23/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,68,,35,115,1.942857143,0.591304348,1.942857143,0.591304348,,104.5,N,N,Y,,2,NORMAL,68,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-17,2/23/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,12,,6,32,2,0.375,2,0.375,,36,N,N,Y,,3,NORMAL,12,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-17,2/23/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,18,,9,34,2,0.529411765,2,0.529411765,,33,N,N,Y,,4,NORMAL,18,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,3/25/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,5.1,-0.3,3.4,5.4,1.411764706,0.888888889,1.5,0.944444444,Y,3.3,N,N,,Y,56,NORMAL,4.8,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,14,3/25/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,5.1,-0.3,3.4,5.4,1.411764706,0.888888889,1.5,0.944444444,Y,3.3,N,N,,Y,56,NORMAL,4.8,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,3/25/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,43,NORMAL,6.84,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,14,3/25/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,43,NORMAL,6.84,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,3/25/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,68,-10,35,115,1.657142857,0.504347826,1.942857143,0.591304348,Y,114.5,N,N,,Y,39,NORMAL,58,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,14,3/25/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,68,-10,35,115,1.657142857,0.504347826,1.942857143,0.591304348,Y,114.5,N,N,,Y,39,NORMAL,58,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,3/25/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,12,0,6,32,2,0.375,2,0.375,Y,36,N,N,,Y,40,NORMAL,12,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,14,3/25/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,12,0,6,32,2,0.375,2,0.375,Y,36,N,N,,Y,40,NORMAL,12,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,3/25/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,9,34,2.222222222,0.588235294,2,0.529411765,Y,31,N,N,,Y,41,NORMAL,20,0,No
CDISCPILOT01,1387,01-701-1387,Placebo,0,Placebo,0,3/12/14,3/25/14,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,14,3/25/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,9,34,2.222222222,0.588235294,2,0.529411765,Y,31,N,N,,Y,41,NORMAL,20,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-11,10/17/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-11,10/17/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-11,10/17/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,76,,35,115,2.171428571,0.660869565,2.171428571,0.660869565,,96.5,N,N,Y,,2,NORMAL,76,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-11,10/17/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,,6,35,3.833333333,0.657142857,3.833333333,0.657142857,,29.5,N,N,Y,,3,NORMAL,23,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-11,10/17/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,11,36,2.272727273,0.694444444,2.272727273,0.694444444,,29,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,11/11/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,3.9,0.1,3.4,5.4,1.176470588,0.740740741,1.147058824,0.722222222,,4.1,N,N,,,56,NORMAL,4,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,11/11/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,11/11/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,76,-2,35,115,2.114285714,0.643478261,2.171428571,0.660869565,,98.5,N,N,,,39,NORMAL,74,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,11/11/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,23,-3,6,35,3.333333333,0.571428571,3.833333333,0.657142857,,32.5,N,N,,,40,NORMAL,20,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,11/11/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,25,-2,11,36,2.090909091,0.638888889,2.272727273,0.694444444,,31,N,N,,,41,NORMAL,23,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,11/24/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.4,3.9,0.5,3.4,5.4,1.294117647,0.814814815,1.147058824,0.722222222,,3.7,N,N,,,90,NORMAL,4.4,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,11/24/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,11/24/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,76,1,35,115,2.2,0.669565217,2.171428571,0.660869565,,95.5,N,N,,,74,NORMAL,77,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,11/24/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,23,-3,6,35,3.333333333,0.571428571,3.833333333,0.657142857,,32.5,N,N,,,75,NORMAL,20,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,11/24/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,25,-5,11,36,1.818181818,0.555555556,2.272727273,0.694444444,,34,N,N,,,76,NORMAL,20,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,12/9/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4,3.9,0.1,3.4,5.4,1.176470588,0.740740741,1.147058824,0.722222222,,4.1,N,N,,,120,NORMAL,4,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,12/9/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,108,NORMAL,10.26,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,12/9/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,85,76,9,35,115,2.428571429,0.739130435,2.171428571,0.660869565,,87.5,N,N,,,104,NORMAL,85,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,12/9/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,23,-2,6,35,3.5,0.6,3.833333333,0.657142857,,31.5,N,N,,,105,NORMAL,21,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,43,12/9/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,25,-3,11,36,2,0.611111111,2.272727273,0.694444444,,32,N,N,,,106,NORMAL,22,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,12/20/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.7,3.9,-0.2,3.4,5.4,1.088235294,0.685185185,1.147058824,0.722222222,Y,4.4,N,N,,,150,NORMAL,3.7,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,12/20/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,138,NORMAL,6.84,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,12/20/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,76,-4,35,115,2.057142857,0.626086957,2.171428571,0.660869565,,100.5,N,N,,,134,NORMAL,72,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,12/20/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,23,-1,6,35,3.666666667,0.628571429,3.833333333,0.657142857,,30.5,N,N,,,135,NORMAL,22,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,54,12/20/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,25,-8,11,36,1.545454545,0.472222222,2.272727273,0.694444444,,37,N,N,,,136,NORMAL,17,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,1/20/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,3.9,0,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,,,181,NORMAL,3.9,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,1/20/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,168,NORMAL,10.26,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,1/20/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,76,4,35,115,2.285714286,0.695652174,2.171428571,0.660869565,,92.5,N,N,,,164,NORMAL,80,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,1/20/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,23,-2,6,35,3.5,0.6,3.833333333,0.657142857,,31.5,N,N,,,165,NORMAL,21,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,1/20/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,25,-1,11,36,2.181818182,0.666666667,2.272727273,0.694444444,,30,N,N,,,166,NORMAL,24,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,2/17/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,3.9,0.2,3.4,5.4,1.205882353,0.759259259,1.147058824,0.722222222,,4,N,N,,,215,NORMAL,4.1,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,2/17/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,203,NORMAL,10.26,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,2/17/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,76,-9,35,115,1.914285714,0.582608696,2.171428571,0.660869565,Y,105.5,N,N,,,199,NORMAL,67,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,2/17/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,23,-5,6,35,3,0.514285714,3.833333333,0.657142857,,34.5,N,N,,,200,NORMAL,18,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,113,2/17/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,25,-3,11,36,2,0.611111111,2.272727273,0.694444444,,32,N,N,,,201,NORMAL,22,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/17/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.9,3.9,0,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,,,245,NORMAL,3.9,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/17/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,233,NORMAL,10.26,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/17/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,76,0,35,115,2.171428571,0.660869565,2.171428571,0.660869565,,96.5,N,N,,,229,NORMAL,76,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/17/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,23,-9,6,35,2.333333333,0.4,3.833333333,0.657142857,,38.5,N,N,,,230,NORMAL,14,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/17/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,25,-8,11,36,1.545454545,0.472222222,2.272727273,0.694444444,,37,N,N,,,231,NORMAL,17,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,170,4/15/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,3.9,-0.1,3.4,5.4,1.117647059,0.703703704,1.147058824,0.722222222,,4.3,N,N,,Y,276,NORMAL,3.8,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,170,4/15/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,3.9,-0.1,3.4,5.4,1.117647059,0.703703704,1.147058824,0.722222222,,4.3,N,N,,Y,276,NORMAL,3.8,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,170,4/15/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,Y,26.37,N,N,,Y,263,NORMAL,5.13,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,170,4/15/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,Y,26.37,N,N,,Y,263,NORMAL,5.13,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,170,4/15/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,76,-8,35,115,1.942857143,0.591304348,2.171428571,0.660869565,,104.5,N,N,,Y,259,NORMAL,68,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,170,4/15/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,76,-8,35,115,1.942857143,0.591304348,2.171428571,0.660869565,,104.5,N,N,,Y,259,NORMAL,68,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,170,4/15/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,23,-10,6,35,2.166666667,0.371428571,3.833333333,0.657142857,Y,39.5,N,N,,Y,260,NORMAL,13,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,170,4/15/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,23,-10,6,35,2.166666667,0.371428571,3.833333333,0.657142857,Y,39.5,N,N,,Y,260,NORMAL,13,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,170,4/15/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,25,-10,11,36,1.363636364,0.416666667,2.272727273,0.694444444,Y,39,N,N,,Y,261,NORMAL,15,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,170,4/15/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,25,-10,11,36,1.363636364,0.416666667,2.272727273,0.694444444,Y,39,N,N,,Y,261,NORMAL,15,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/28/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4,3.9,0.1,3.4,5.4,1.176470588,0.740740741,1.147058824,0.722222222,,4.1,N,N,,,310,NORMAL,4,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/28/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,298,NORMAL,6.84,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/28/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,76,-3,35,115,2.085714286,0.634782609,2.171428571,0.660869565,,99.5,N,N,,,294,NORMAL,73,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/28/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,23,-6,6,35,2.833333333,0.485714286,3.833333333,0.657142857,,35.5,N,N,,,295,NORMAL,17,0,No
CDISCPILOT01,1392,01-701-1392,Placebo,0,Placebo,0,10/28/12,4/28/13,78,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,183,4/28/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,25,-6,11,36,1.727272727,0.527777778,2.272727273,0.694444444,,35,N,N,,,296,NORMAL,19,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-8,9/15/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.8,3.8,,3.4,5.4,1.117647059,0.703703704,1.117647059,0.703703704,,4.3,N,N,Y,,19,NORMAL,3.8,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-8,9/15/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-8,9/15/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,28,28,,35,115,0.8,0.243478261,0.8,0.243478261,,144.5,N,N,Y,,2,LOW,28,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-8,9/15/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,,6,35,2.166666667,0.371428571,2.166666667,0.371428571,,39.5,N,N,Y,,3,NORMAL,13,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-8,9/15/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,,11,36,1.363636364,0.416666667,1.363636364,0.416666667,,39,N,N,Y,,4,NORMAL,15,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,10/7/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,3.8,0.6,3.4,5.4,1.294117647,0.814814815,1.117647059,0.703703704,,3.7,N,N,,,61,NORMAL,4.4,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,10/7/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,48,NORMAL,10.26,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,10/7/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,33,28,5,35,115,0.942857143,0.286956522,0.8,0.243478261,,139.5,N,N,,,44,LOW,33,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,10/7/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,13,3,6,35,2.666666667,0.457142857,2.166666667,0.371428571,,36.5,N,N,,,45,NORMAL,16,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,10/7/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,15,3,11,36,1.636363636,0.5,1.363636364,0.416666667,,36,N,N,,,46,NORMAL,18,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 4,4,28,10/20/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.2,3.8,0.4,3.4,5.4,1.235294118,0.777777778,1.117647059,0.703703704,,3.9,N,N,,,97,NORMAL,4.2,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 4,4,28,10/20/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,84,NORMAL,10.26,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 4,4,28,10/20/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,32,28,4,35,115,0.914285714,0.27826087,0.8,0.243478261,Y,140.5,N,N,,,79,LOW,32,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 4,4,28,10/20/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,35,2.333333333,0.4,2.166666667,0.371428571,,38.5,N,N,,,80,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 4,4,28,10/20/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,15,1,11,36,1.454545455,0.444444444,1.363636364,0.416666667,,38,N,N,,,82,NORMAL,16,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,3.8,0.5,3.4,5.4,1.264705882,0.796296296,1.117647059,0.703703704,,3.8,N,N,,,127,NORMAL,4.3,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,115,NORMAL,10.26,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,33,28,5,35,115,0.942857143,0.286956522,0.8,0.243478261,,139.5,N,N,,,111,LOW,33,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,35,2.333333333,0.4,2.166666667,0.371428571,,38.5,N,N,,,112,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,11/4/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,0,11,36,1.363636364,0.416666667,1.363636364,0.416666667,,39,N,N,,,113,NORMAL,15,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 8,8,60,11/21/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.2,3.8,0.4,3.4,5.4,1.235294118,0.777777778,1.117647059,0.703703704,,3.9,N,N,,,157,NORMAL,4.2,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 8,8,60,11/21/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,13.68,-5.13,3,21,2.85,0.407142857,4.56,0.651428571,,22.95,N,N,,,145,NORMAL,8.55,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 8,8,60,11/21/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,37,28,9,35,115,1.057142857,0.32173913,0.8,0.243478261,,135.5,N,N,,,141,NORMAL,37,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 8,8,60,11/21/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,13,3,6,35,2.666666667,0.457142857,2.166666667,0.371428571,,36.5,N,N,,,142,NORMAL,16,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 8,8,60,11/21/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,11,36,1.272727273,0.388888889,1.363636364,0.416666667,Y,40,N,N,,,143,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 12,12,90,12/21/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,3.8,0.4,3.4,5.4,1.235294118,0.777777778,1.117647059,0.703703704,,3.9,N,N,,,188,NORMAL,4.2,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 12,12,90,12/21/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,175,NORMAL,10.26,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 12,12,90,12/21/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,32,28,4,35,115,0.914285714,0.27826087,0.8,0.243478261,,140.5,N,N,,,171,LOW,32,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 12,12,90,12/21/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,13,-1,6,35,2,0.342857143,2.166666667,0.371428571,,40.5,N,N,,,172,NORMAL,12,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 12,12,90,12/21/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,0,11,36,1.363636364,0.416666667,1.363636364,0.416666667,,39,N,N,,,173,NORMAL,15,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 16,16,114,1/14/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,3.8,0.3,3.4,5.4,1.205882353,0.759259259,1.117647059,0.703703704,,4,N,N,,,221,NORMAL,4.1,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 16,16,114,1/14/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,13.68,-5.13,3,21,2.85,0.407142857,4.56,0.651428571,,22.95,N,N,,,209,NORMAL,8.55,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 16,16,114,1/14/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,39,28,11,35,115,1.114285714,0.339130435,0.8,0.243478261,,133.5,N,N,,,205,NORMAL,39,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 16,16,114,1/14/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,13,-3,6,35,1.666666667,0.285714286,2.166666667,0.371428571,Y,42.5,N,N,,,206,NORMAL,10,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 16,16,114,1/14/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,0,11,36,1.363636364,0.416666667,1.363636364,0.416666667,,39,N,N,,,207,NORMAL,15,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 20,20,141,2/10/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.6,3.8,0.8,3.4,5.4,1.352941176,0.851851852,1.117647059,0.703703704,,3.5,N,N,,,251,NORMAL,4.6,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 20,20,141,2/10/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,13.68,-6.84,3,21,2.28,0.325714286,4.56,0.651428571,Y,24.66,N,N,,,239,NORMAL,6.84,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 20,20,141,2/10/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,37,28,9,35,115,1.057142857,0.32173913,0.8,0.243478261,,135.5,N,N,,,235,NORMAL,37,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 20,20,141,2/10/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,35,2.333333333,0.4,2.166666667,0.371428571,,38.5,N,N,,,236,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 20,20,141,2/10/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,11,36,1.272727273,0.388888889,1.363636364,0.416666667,,40,N,N,,,237,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,3/10/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,3.8,0.1,3.4,5.4,1.147058824,0.722222222,1.117647059,0.703703704,Y,4.2,N,N,,Y,282,NORMAL,3.9,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/10/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,3.8,0.1,3.4,5.4,1.147058824,0.722222222,1.117647059,0.703703704,Y,4.2,N,N,,Y,282,NORMAL,3.9,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,3/10/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,13.68,-5.13,3,21,2.85,0.407142857,4.56,0.651428571,,22.95,N,N,,Y,269,NORMAL,8.55,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/10/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,13.68,-5.13,3,21,2.85,0.407142857,4.56,0.651428571,,22.95,N,N,,Y,269,NORMAL,8.55,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,3/10/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,35,28,7,35,115,1,0.304347826,0.8,0.243478261,,137.5,N,N,,Y,265,NORMAL,35,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/10/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,35,28,7,35,115,1,0.304347826,0.8,0.243478261,,137.5,N,N,,Y,265,NORMAL,35,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,3/10/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,35,2.333333333,0.4,2.166666667,0.371428571,,38.5,N,N,,Y,266,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/10/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,35,2.333333333,0.4,2.166666667,0.371428571,,38.5,N,N,,Y,266,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 24,24,169,3/10/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,11,36,1.272727273,0.388888889,1.363636364,0.416666667,,40,N,N,,Y,267,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,169,3/10/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,11,36,1.272727273,0.388888889,1.363636364,0.416666667,,40,N,N,,Y,267,NORMAL,14,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,3/24/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4,3.8,0.2,3.4,5.4,1.176470588,0.740740741,1.117647059,0.703703704,,4.1,N,N,,,316,NORMAL,4,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,3/24/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,304,NORMAL,13.68,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,3/24/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,31,28,3,35,115,0.885714286,0.269565217,0.8,0.243478261,,141.5,N,N,,,300,LOW,31,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,3/24/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,35,2.166666667,0.371428571,2.166666667,0.371428571,,39.5,N,N,,,301,NORMAL,13,0,No
CDISCPILOT01,1415,01-701-1415,Placebo,0,Placebo,0,9/23/13,3/24/14,85,>80,3,WHITE,1,M,Y,,Y, Week 26,26,183,3/24/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,15,1,11,36,1.454545455,0.444444444,1.363636364,0.416666667,,38,N,N,,,302,NORMAL,16,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-26,2/21/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-26,2/21/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-26,2/21/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,80,,35,115,2.285714286,0.695652174,2.285714286,0.695652174,,92.5,N,N,Y,,2,NORMAL,80,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-26,2/21/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,28,28,,6,32,4.666666667,0.875,4.666666667,0.875,,25,N,N,Y,,3,NORMAL,28,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-26,2/21/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,26,,9,34,2.888888889,0.764705882,2.888888889,0.764705882,,25,N,N,Y,,4,NORMAL,26,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/2/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,3.9,0.4,3.4,5.4,1.264705882,0.796296296,1.147058824,0.722222222,,3.8,N,N,,,56,NORMAL,4.3,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/2/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,13.68,8.55,5.13,3,21,4.56,0.651428571,2.85,0.407142857,,17.82,N,N,,,43,NORMAL,13.68,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/2/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,80,-10,35,115,2,0.608695652,2.285714286,0.695652174,,102.5,N,N,,,39,NORMAL,70,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/2/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,28,-8,6,32,3.333333333,0.625,4.666666667,0.875,,28,N,N,,,40,NORMAL,20,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/2/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,26,5,9,34,3.444444444,0.911764706,2.888888889,0.764705882,,26.5,N,N,,,41,NORMAL,31,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,29,4/16/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,3.9,0,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,Y,4.2,N,N,,,90,NORMAL,3.9,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,29,4/16/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,,78,NORMAL,11.97,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,29,4/16/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,80,-15,35,115,1.857142857,0.565217391,2.285714286,0.695652174,Y,107.5,N,N,,,74,NORMAL,65,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,29,4/16/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,28,-12,6,32,2.666666667,0.5,4.666666667,0.875,Y,32,N,N,,,75,NORMAL,16,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,29,4/16/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,26,-3,9,34,2.555555556,0.676470588,2.888888889,0.764705882,,28,N,N,,,76,NORMAL,23,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,4/30/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,3.9,0.2,3.4,5.4,1.205882353,0.759259259,1.147058824,0.722222222,,4,N,N,,Y,121,NORMAL,4.1,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,43,4/30/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,3.9,0.2,3.4,5.4,1.205882353,0.759259259,1.147058824,0.722222222,,4,N,N,,Y,121,NORMAL,4.1,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,4/30/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,Y,22.95,N,N,,Y,108,NORMAL,8.55,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,43,4/30/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,Y,22.95,N,N,,Y,108,NORMAL,8.55,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,4/30/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,80,-12,35,115,1.942857143,0.591304348,2.285714286,0.695652174,,104.5,N,N,,Y,104,NORMAL,68,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,43,4/30/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,80,-12,35,115,1.942857143,0.591304348,2.285714286,0.695652174,,104.5,N,N,,Y,104,NORMAL,68,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,4/30/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,28,-10,6,32,3,0.5625,4.666666667,0.875,,30,N,N,,Y,105,NORMAL,18,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,43,4/30/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,28,-10,6,32,3,0.5625,4.666666667,0.875,,30,N,N,,Y,105,NORMAL,18,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,4/30/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,26,-4,9,34,2.444444444,0.647058824,2.888888889,0.764705882,Y,29,N,N,,Y,106,NORMAL,22,0,No
CDISCPILOT01,1429,01-701-1429,Xanomeline Low Dose,54,Xanomeline Low Dose,54,3/19/13,4/30/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,43,4/30/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,26,-4,9,34,2.444444444,0.647058824,2.888888889,0.764705882,Y,29,N,N,,Y,106,NORMAL,22,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-15,7/24/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.2,4.2,,3.4,5.4,1.235294118,0.777777778,1.235294118,0.777777778,,3.9,N,N,Y,,19,NORMAL,4.2,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-15,7/24/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-15,7/24/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,74,,35,115,2.114285714,0.643478261,2.114285714,0.643478261,,98.5,N,N,Y,,2,NORMAL,74,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-15,7/24/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,,6,35,3.5,0.6,3.5,0.6,,31.5,N,N,Y,,3,NORMAL,21,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-15,7/24/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,31,,11,36,2.818181818,0.861111111,2.818181818,0.861111111,,25.5,N,N,Y,,4,NORMAL,31,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,16,8/23/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.7,4.2,-0.5,3.4,5.4,1.088235294,0.685185185,1.235294118,0.777777778,Y,4.4,N,N,,,56,NORMAL,3.7,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,16,8/23/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,16,8/23/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,74,-8,35,115,1.885714286,0.573913043,2.114285714,0.643478261,Y,106.5,N,N,,,39,NORMAL,66,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,16,8/23/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,35,3,0.514285714,3.5,0.6,,34.5,N,N,,,40,NORMAL,18,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,16,8/23/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,31,-7,11,36,2.181818182,0.666666667,2.818181818,0.861111111,,30,N,N,,,41,NORMAL,24,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,9/4/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.8,4.2,-0.4,3.4,5.4,1.117647059,0.703703704,1.235294118,0.777777778,,4.3,N,N,,,90,NORMAL,3.8,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,9/4/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,9/4/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,74,-7,35,115,1.914285714,0.582608696,2.114285714,0.643478261,,105.5,N,N,,,74,NORMAL,67,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,9/4/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,35,3,0.514285714,3.5,0.6,,34.5,N,N,,,75,NORMAL,18,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,28,9/4/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,31,-5,11,36,2.363636364,0.722222222,2.818181818,0.861111111,,28,N,N,,,76,NORMAL,26,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,46,9/22/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.8,4.2,0.6,3.4,5.4,1.411764706,0.888888889,1.235294118,0.777777778,,3.3,N,N,,,120,NORMAL,4.8,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,46,9/22/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,46,9/22/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,74,5,35,115,2.257142857,0.686956522,2.114285714,0.643478261,,93.5,N,N,,,104,NORMAL,79,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,46,9/22/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,21,5,6,35,4.333333333,0.742857143,3.5,0.6,,26.5,N,N,,,105,NORMAL,26,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,46,9/22/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,31,0,11,36,2.818181818,0.861111111,2.818181818,0.861111111,,25.5,N,N,,,106,NORMAL,31,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,10/3/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.9,4.2,0.7,3.4,5.4,1.441176471,0.907407407,1.235294118,0.777777778,,3.2,N,N,,,150,NORMAL,4.9,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,10/3/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,138,NORMAL,6.84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,10/3/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,74,9,35,115,2.371428571,0.72173913,2.114285714,0.643478261,,89.5,N,N,,,134,NORMAL,83,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,10/3/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,21,-1,6,35,3.333333333,0.571428571,3.5,0.6,,32.5,N,N,,,135,NORMAL,20,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,57,10/3/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,31,-5,11,36,2.363636364,0.722222222,2.818181818,0.861111111,,28,N,N,,,136,NORMAL,26,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,10/31/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.8,4.2,0.6,3.4,5.4,1.411764706,0.888888889,1.235294118,0.777777778,,3.3,N,N,,,181,NORMAL,4.8,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,10/31/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,168,NORMAL,6.84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,10/31/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,74,0,35,115,2.114285714,0.643478261,2.114285714,0.643478261,,98.5,N,N,,,164,NORMAL,74,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,10/31/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,21,-9,6,35,2,0.342857143,3.5,0.6,Y,40.5,N,N,,,165,NORMAL,12,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,10/31/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,31,-8,11,36,2.090909091,0.638888889,2.818181818,0.861111111,Y,31,N,N,,,166,NORMAL,23,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,11/27/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,4.2,-0.2,3.4,5.4,1.176470588,0.740740741,1.235294118,0.777777778,,4.1,N,N,,,215,NORMAL,4,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,11/27/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,203,NORMAL,8.55,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,11/27/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,87,74,13,35,115,2.485714286,0.756521739,2.114285714,0.643478261,,85.5,N,N,,,199,NORMAL,87,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,11/27/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,21,1,6,35,3.666666667,0.628571429,3.5,0.6,,30.5,N,N,,,200,NORMAL,22,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,11/27/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,31,-1,11,36,2.727272727,0.833333333,2.818181818,0.861111111,,24.5,N,N,,,201,NORMAL,30,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,140,12/25/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.2,0,3.4,5.4,1.235294118,0.777777778,1.235294118,0.777777778,,3.9,N,N,,,245,NORMAL,4.2,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,140,12/25/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,Y,26.37,N,N,,,233,NORMAL,5.13,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,140,12/25/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,74,5,35,115,2.257142857,0.686956522,2.114285714,0.643478261,,93.5,N,N,,,229,NORMAL,79,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,140,12/25/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,21,-4,6,35,2.833333333,0.485714286,3.5,0.6,,35.5,N,N,,,230,NORMAL,17,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,140,12/25/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,31,-4,11,36,2.454545455,0.75,2.818181818,0.861111111,,27,N,N,,,231,NORMAL,27,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,168,1/22/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.2,0.3,3.4,5.4,1.323529412,0.833333333,1.235294118,0.777777778,,3.6,N,N,,Y,276,NORMAL,4.5,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,168,1/22/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.2,0.3,3.4,5.4,1.323529412,0.833333333,1.235294118,0.777777778,,3.6,N,N,,Y,276,NORMAL,4.5,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,168,1/22/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,168,1/22/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,168,1/22/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,74,10,35,115,2.4,0.730434783,2.114285714,0.643478261,,88.5,N,N,,Y,259,NORMAL,84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,168,1/22/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,74,10,35,115,2.4,0.730434783,2.114285714,0.643478261,,88.5,N,N,,Y,259,NORMAL,84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,168,1/22/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,35,3,0.514285714,3.5,0.6,,34.5,N,N,,Y,260,NORMAL,18,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,168,1/22/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,35,3,0.514285714,3.5,0.6,,34.5,N,N,,Y,260,NORMAL,18,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,168,1/22/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,31,-2,11,36,2.636363636,0.805555556,2.818181818,0.861111111,,25,N,N,,Y,261,NORMAL,29,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,168,1/22/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,31,-2,11,36,2.636363636,0.805555556,2.818181818,0.861111111,,25,N,N,,Y,261,NORMAL,29,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,182,2/5/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,3.9,4.2,-0.3,3.4,5.4,1.147058824,0.722222222,1.235294118,0.777777778,,4.2,N,N,,,310,NORMAL,3.9,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,182,2/5/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,182,2/5/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,74,10,35,115,2.4,0.730434783,2.114285714,0.643478261,,88.5,N,N,,,294,NORMAL,84,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,182,2/5/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,21,-4,6,35,2.833333333,0.485714286,3.5,0.6,,35.5,N,N,,,295,NORMAL,17,0,No
CDISCPILOT01,1440,01-701-1440,Placebo,0,Placebo,0,8/8/13,2/5/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,182,2/5/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,31,-6,11,36,2.272727273,0.694444444,2.818181818,0.861111111,,29,N,N,,,296,NORMAL,25,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-9,10/17/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-9,10/17/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-9,10/17/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,64,,31,110,2.064516129,0.581818182,2.064516129,0.581818182,,101,N,N,Y,,2,NORMAL,64,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-9,10/17/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,,6,34,3.833333333,0.676470588,3.833333333,0.676470588,,28,N,N,Y,,3,NORMAL,23,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-9,10/17/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,14,,9,34,1.555555556,0.411764706,1.555555556,0.411764706,,37,N,N,Y,,4,NORMAL,14,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,15,11/9/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4,0.2,3.4,5.4,1.235294118,0.777777778,1.176470588,0.740740741,,3.9,N,N,,,56,NORMAL,4.2,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,15,11/9/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,15,11/9/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,64,3,31,110,2.161290323,0.609090909,2.064516129,0.581818182,,98,N,N,,,39,NORMAL,67,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,15,11/9/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,23,-3,6,34,3.333333333,0.588235294,3.833333333,0.676470588,,31,N,N,,,40,NORMAL,20,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,15,11/9/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,14,-1,9,34,1.444444444,0.382352941,1.555555556,0.411764706,,38,N,N,,,41,NORMAL,13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,11/23/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,4,-0.1,3.4,5.4,1.147058824,0.722222222,1.176470588,0.740740741,,4.2,N,N,,,90,NORMAL,3.9,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,11/23/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,3.42,8.55,-5.13,3,21,1.14,0.162857143,2.85,0.407142857,Y,28.08,N,N,,,78,NORMAL,3.42,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,11/23/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,64,9,31,110,2.35483871,0.663636364,2.064516129,0.581818182,,92,N,N,,,74,NORMAL,73,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,11/23/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,23,-5,6,34,3,0.529411765,3.833333333,0.676470588,,33,N,N,,,75,NORMAL,18,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,29,11/23/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,12,14,-2,9,34,1.333333333,0.352941176,1.555555556,0.411764706,Y,39,N,N,,,76,NORMAL,12,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,12/7/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.7,4,-0.3,3.4,5.4,1.088235294,0.685185185,1.176470588,0.740740741,Y,4.4,N,N,,,120,NORMAL,3.7,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,12/7/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,108,NORMAL,6.84,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,12/7/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,64,2,31,110,2.129032258,0.6,2.064516129,0.581818182,,99,N,N,,,104,NORMAL,66,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,12/7/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,0,6,34,3.833333333,0.676470588,3.833333333,0.676470588,,28,N,N,,,105,NORMAL,23,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,43,12/7/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,14,-1,9,34,1.444444444,0.382352941,1.555555556,0.411764706,,38,N,N,,,106,NORMAL,13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,62,12/26/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,150,NORMAL,4.1,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,62,12/26/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,138,NORMAL,6.84,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,62,12/26/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,64,-5,31,110,1.903225806,0.536363636,2.064516129,0.581818182,Y,106,N,N,,,134,NORMAL,59,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,62,12/26/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,23,-4,6,34,3.166666667,0.558823529,3.833333333,0.676470588,,32,N,N,,,135,NORMAL,19,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,62,12/26/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,14,1,9,34,1.666666667,0.441176471,1.555555556,0.411764706,,36,N,N,,,136,NORMAL,15,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,1/18/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,181,NORMAL,4.1,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,1/18/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,,168,NORMAL,5.13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,1/18/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,64,0,31,110,2.064516129,0.581818182,2.064516129,0.581818182,,101,N,N,,,164,NORMAL,64,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,1/18/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,23,6,6,34,4.833333333,0.852941176,3.833333333,0.676470588,,26,N,N,,,165,NORMAL,29,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,1/18/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,14,1,9,34,1.666666667,0.441176471,1.555555556,0.411764706,,36,N,N,,,166,NORMAL,15,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,2/15/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.3,4,0.3,3.4,5.4,1.264705882,0.796296296,1.176470588,0.740740741,,3.8,N,N,,,215,NORMAL,4.3,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,2/15/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,,203,NORMAL,5.13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,2/15/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,64,2,31,110,2.129032258,0.6,2.064516129,0.581818182,,99,N,N,,,199,NORMAL,66,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,2/15/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,23,-7,6,34,2.666666667,0.470588235,3.833333333,0.676470588,Y,35,N,N,,,200,NORMAL,16,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,113,2/15/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,14,1,9,34,1.666666667,0.441176471,1.555555556,0.411764706,,36,N,N,,,201,NORMAL,15,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,3/15/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,,245,NORMAL,4,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,3/15/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,,233,NORMAL,5.13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,3/15/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,64,12,31,110,2.451612903,0.690909091,2.064516129,0.581818182,,89,N,N,,,229,NORMAL,76,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,3/15/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,30,23,7,6,34,5,0.882352941,3.833333333,0.676470588,,27,N,N,,,230,NORMAL,30,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,3/15/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,12,14,-2,9,34,1.333333333,0.352941176,1.555555556,0.411764706,,39,N,N,,,231,NORMAL,12,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,174,4/17/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,Y,276,NORMAL,4.1,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,174,4/17/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,Y,276,NORMAL,4.1,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,174,4/17/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,Y,263,NORMAL,5.13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,174,4/17/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,Y,263,NORMAL,5.13,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,174,4/17/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,64,22,31,110,2.774193548,0.781818182,2.064516129,0.581818182,,79,N,N,,Y,259,NORMAL,86,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,174,4/17/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,64,22,31,110,2.774193548,0.781818182,2.064516129,0.581818182,,79,N,N,,Y,259,NORMAL,86,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,174,4/17/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,23,10,6,34,5.5,0.970588235,3.833333333,0.676470588,,30,N,N,,Y,260,NORMAL,33,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,174,4/17/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,23,10,6,34,5.5,0.970588235,3.833333333,0.676470588,,30,N,N,,Y,260,NORMAL,33,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,174,4/17/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,14,3,9,34,1.888888889,0.5,1.555555556,0.411764706,,34,N,N,,Y,261,NORMAL,17,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,174,4/17/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,14,3,9,34,1.888888889,0.5,1.555555556,0.411764706,,34,N,N,,Y,261,NORMAL,17,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,4/26/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.3,4,0.3,3.4,5.4,1.264705882,0.796296296,1.176470588,0.740740741,,3.8,N,N,,,310,NORMAL,4.3,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,4/26/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,298,NORMAL,6.84,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,4/26/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,64,14,31,110,2.516129032,0.709090909,2.064516129,0.581818182,,87,N,N,,,294,NORMAL,78,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,4/26/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,23,10,6,34,5.5,0.970588235,3.833333333,0.676470588,,30,N,N,,,295,NORMAL,33,0,No
CDISCPILOT01,1442,01-701-1442,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/26/13,4/26/14,57,<65,1,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,183,4/26/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,14,0,9,34,1.555555556,0.411764706,1.555555556,0.411764706,,37,N,N,,,296,NORMAL,14,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-5,12/31/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-5,12/31/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-5,12/31/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,102,102,,35,115,2.914285714,0.886956522,2.914285714,0.886956522,,84.5,N,N,Y,,2,NORMAL,102,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-5,12/31/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,43,3.166666667,0.441860465,3.166666667,0.441860465,,45.5,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Baseline,0,-5,12/31/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,,11,36,1.727272727,0.527777778,1.727272727,0.527777778,,35,N,N,Y,,4,NORMAL,19,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,,3.9,N,N,,,56,NORMAL,4.2,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,Y,17.82,N,N,,,43,NORMAL,13.68,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,102,-7,35,115,2.714285714,0.826086957,2.914285714,0.886956522,,77.5,N,N,,,39,NORMAL,95,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,19,-1,6,43,3,0.418604651,3.166666667,0.441860465,,46.5,N,N,,,40,NORMAL,18,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 2,2,14,1/18/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,19,-1,11,36,1.636363636,0.5,1.727272727,0.527777778,Y,36,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,1/31/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.3,0.3,3.4,5.4,1.352941176,0.851851852,1.264705882,0.796296296,,3.5,N,N,,,90,NORMAL,4.6,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,1/31/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,78,NORMAL,13.68,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,1/31/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,100,102,-2,35,115,2.857142857,0.869565217,2.914285714,0.886956522,Y,82.5,N,N,,,74,NORMAL,100,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,1/31/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,19,-2,6,43,2.833333333,0.395348837,3.166666667,0.441860465,Y,47.5,N,N,,,75,NORMAL,17,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 4,4,27,1/31/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,19,-1,11,36,1.636363636,0.5,1.727272727,0.527777778,,36,N,N,,,76,NORMAL,18,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,2/13/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,Y,4,N,N,,Y,121,NORMAL,4.1,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,2/13/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,Y,4,N,N,,Y,121,NORMAL,4.1,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,2/13/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,17.1,13.68,3.42,3,21,5.7,0.814285714,4.56,0.651428571,,15.6,N,N,,Y,108,NORMAL,17.1,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,2/13/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,17.1,13.68,3.42,3,21,5.7,0.814285714,4.56,0.651428571,,15.6,N,N,,Y,108,NORMAL,17.1,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,2/13/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,102,-4,35,115,2.8,0.852173913,2.914285714,0.886956522,,80.5,N,N,,Y,104,NORMAL,98,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,2/13/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,102,-4,35,115,2.8,0.852173913,2.914285714,0.886956522,,80.5,N,N,,Y,104,NORMAL,98,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,2/13/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,19,4,6,43,3.833333333,0.534883721,3.166666667,0.441860465,,41.5,N,N,,Y,105,NORMAL,23,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,2/13/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,19,4,6,43,3.833333333,0.534883721,3.166666667,0.441860465,,41.5,N,N,,Y,105,NORMAL,23,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y, Week 6,6,40,2/13/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,0,11,36,1.727272727,0.527777778,1.727272727,0.527777778,,35,N,N,,Y,106,NORMAL,19,0,No
CDISCPILOT01,1444,01-701-1444,Xanomeline High Dose,81,Xanomeline High Dose,81,1/5/13,2/12/13,63,<65,1,WHITE,1,M,N,Y,Y,End of Treatment,99,40,2/13/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,0,11,36,1.727272727,0.527777778,1.727272727,0.527777778,,35,N,N,,Y,106,NORMAL,19,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-23,7/3/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-23,7/3/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-23,7/3/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,72,,35,115,2.057142857,0.626086957,2.057142857,0.626086957,,100.5,N,N,Y,,2,NORMAL,72,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-23,7/3/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,20,,6,32,3.333333333,0.625,3.333333333,0.625,,28,N,N,Y,,3,NORMAL,20,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Baseline,0,-23,7/3/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, .,,-2,7/24/13,UNSCHEDULED 1.1,1.1,Potassium (mmol/L),K,19,CHEM,4.2,4.5,-0.3,3.4,5.4,1.235294118,0.777777778,1.323529412,0.833333333,,3.9,N,N,,,52,NORMAL,4.2,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, .,,-2,7/24/13,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,42,NORMAL,8.55,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, .,,-2,7/24/13,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,72,0,35,115,2.057142857,0.626086957,2.057142857,0.626086957,,100.5,N,N,,,39,NORMAL,72,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, .,,-2,7/24/13,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,37,20,17,6,32,6.166666667,1.15625,3.333333333,0.625,,34,N,N,,,40,HIGH,37,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, .,,-2,7/24/13,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,44,25,19,9,34,4.888888889,1.294117647,2.777777778,0.735294118,,39.5,N,N,,,41,HIGH,44,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,8/8/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.5,-0.1,3.4,5.4,1.294117647,0.814814815,1.323529412,0.833333333,,3.7,N,N,,,92,NORMAL,4.4,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,8/8/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,79,NORMAL,6.84,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,8/8/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,72,-2,35,115,2,0.608695652,2.057142857,0.626086957,,102.5,N,N,,,75,NORMAL,70,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,8/8/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,35,20,15,6,32,5.833333333,1.09375,3.333333333,0.625,Y,32,N,N,,,76,HIGH,35,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 2,2,14,8/8/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,41,25,16,9,34,4.555555556,1.205882353,2.777777778,0.735294118,Y,36.5,N,N,,,77,HIGH,41,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,8/24/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.5,0.1,3.4,5.4,1.352941176,0.851851852,1.323529412,0.833333333,,3.5,N,N,,,126,NORMAL,4.6,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,8/24/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,114,NORMAL,8.55,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,8/24/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,72,-7,35,115,1.857142857,0.565217391,2.057142857,0.626086957,,107.5,N,N,,,110,NORMAL,65,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,8/24/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,20,6,6,32,4.333333333,0.8125,3.333333333,0.625,,23,N,N,,,111,NORMAL,26,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,8/24/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,25,10,9,34,3.888888889,1.029411765,2.777777778,0.735294118,,30.5,N,N,,,112,HIGH,35,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,9/6/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,4.5,-0.3,3.4,5.4,1.235294118,0.777777778,1.323529412,0.833333333,Y,3.9,N,N,,,156,NORMAL,4.2,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,9/6/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,144,NORMAL,8.55,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,9/6/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,72,-8,35,115,1.828571429,0.556521739,2.057142857,0.626086957,Y,108.5,N,N,,,140,NORMAL,64,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,9/6/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,20,5,6,32,4.166666667,0.78125,3.333333333,0.625,,23,N,N,,,141,NORMAL,25,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 6,6,43,9/6/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,25,7,9,34,3.555555556,0.941176471,2.777777778,0.735294118,,27.5,N,N,,,142,NORMAL,32,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 8,8,65,9/28/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.8,4.5,0.3,3.4,5.4,1.411764706,0.888888889,1.323529412,0.833333333,,3.3,N,N,,,186,NORMAL,4.8,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 8,8,65,9/28/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,174,NORMAL,10.26,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 8,8,65,9/28/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,72,-7,35,115,1.857142857,0.565217391,2.057142857,0.626086957,,107.5,N,N,,,170,NORMAL,65,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 8,8,65,9/28/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,20,4,6,32,4,0.75,3.333333333,0.625,,24,N,N,,,171,NORMAL,24,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 8,8,65,9/28/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,36,25,11,9,34,4,1.058823529,2.777777778,0.735294118,,31.5,N,N,,,172,HIGH,36,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 12,12,115,11/17/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.5,-0.1,3.4,5.4,1.294117647,0.814814815,1.323529412,0.833333333,,3.7,N,N,,Y,217,NORMAL,4.4,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,115,11/17/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.5,-0.1,3.4,5.4,1.294117647,0.814814815,1.323529412,0.833333333,,3.7,N,N,,Y,217,NORMAL,4.4,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 12,12,115,11/17/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,204,NORMAL,8.55,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,115,11/17/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,204,NORMAL,8.55,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 12,12,115,11/17/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,72,-5,35,115,1.914285714,0.582608696,2.057142857,0.626086957,,105.5,N,N,,Y,200,NORMAL,67,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,115,11/17/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,72,-5,35,115,1.914285714,0.582608696,2.057142857,0.626086957,,105.5,N,N,,Y,200,NORMAL,67,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 12,12,115,11/17/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,20,3,6,32,3.833333333,0.71875,3.333333333,0.625,,25,N,N,,Y,201,NORMAL,23,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,115,11/17/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,20,3,6,32,3.833333333,0.71875,3.333333333,0.625,,25,N,N,,Y,201,NORMAL,23,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y, Week 12,12,115,11/17/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,9,34,3.333333333,0.882352941,2.777777778,0.735294118,,25.5,N,N,,Y,202,NORMAL,30,0,No
CDISCPILOT01,1082,01-702-1082,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/26/13,10/13/13,84,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,115,11/17/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,9,34,3.333333333,0.882352941,2.777777778,0.735294118,,25.5,N,N,,Y,202,NORMAL,30,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-65,12/27/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-65,12/27/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-65,12/27/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,76,,35,115,2.171428571,0.660869565,2.171428571,0.660869565,,96.5,N,N,Y,,2,NORMAL,76,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-65,12/27/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,14,,6,43,2.333333333,0.325581395,2.333333333,0.325581395,,50.5,N,N,Y,,3,NORMAL,14,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Baseline,0,-65,12/27/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,11,36,2.272727273,0.694444444,2.272727273,0.694444444,,29,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, .,,-9,2/21/13,UNSCHEDULED 1.1,1.1,Potassium (mmol/L),K,19,CHEM,3.9,4,-0.1,3.4,5.4,1.147058824,0.722222222,1.176470588,0.740740741,,4.2,N,N,,,56,NORMAL,3.9,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, .,,-9,2/21/13,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, .,,-9,2/21/13,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,76,15,35,115,2.6,0.791304348,2.171428571,0.660869565,,81.5,N,N,,,39,NORMAL,91,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, .,,-9,2/21/13,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,14,5,6,43,3.166666667,0.441860465,2.333333333,0.325581395,,45.5,N,N,,,40,NORMAL,19,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, .,,-9,2/21/13,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,25,4,11,36,2.636363636,0.805555556,2.272727273,0.694444444,,25,N,N,,,41,NORMAL,29,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 2,2,13,3/14/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,,93,NORMAL,4.4,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 2,2,13,3/14/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,13.68,-1.71,3,21,3.99,0.57,4.56,0.651428571,,19.53,N,N,,,80,NORMAL,11.97,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 2,2,13,3/14/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,107,76,31,35,115,3.057142857,0.930434783,2.171428571,0.660869565,Y,89.5,N,N,,,76,NORMAL,107,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 2,2,13,3/14/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,14,0,6,43,2.333333333,0.325581395,2.333333333,0.325581395,Y,50.5,N,N,,,77,NORMAL,14,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 2,2,13,3/14/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,11,36,2.727272727,0.833333333,2.272727273,0.694444444,,24.5,N,N,,,78,NORMAL,30,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 4,4,27,3/28/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4,0.3,3.4,5.4,1.264705882,0.796296296,1.176470588,0.740740741,,3.8,N,N,,,128,NORMAL,4.3,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 4,4,27,3/28/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,13.68,-5.13,3,21,2.85,0.407142857,4.56,0.651428571,Y,22.95,N,N,,,116,NORMAL,8.55,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 4,4,27,3/28/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,100,76,24,35,115,2.857142857,0.869565217,2.171428571,0.660869565,,82.5,N,N,,,111,NORMAL,100,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 4,4,27,3/28/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,14,3,6,43,2.833333333,0.395348837,2.333333333,0.325581395,,47.5,N,N,,,112,NORMAL,17,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 4,4,27,3/28/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,25,4,11,36,2.636363636,0.805555556,2.272727273,0.694444444,,25,N,N,,,114,NORMAL,29,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/13/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.6,4,0.6,3.4,5.4,1.352941176,0.851851852,1.176470588,0.740740741,,3.5,N,N,,,158,NORMAL,4.6,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/13/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,17.1,13.68,3.42,3,21,5.7,0.814285714,4.56,0.651428571,,15.6,N,N,,,146,NORMAL,17.1,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/13/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,76,19,35,115,2.714285714,0.826086957,2.171428571,0.660869565,,77.5,N,N,,,142,NORMAL,95,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/13/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,14,6,6,43,3.333333333,0.465116279,2.333333333,0.325581395,,44.5,N,N,,,143,NORMAL,20,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 6,6,43,4/13/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,25,4,11,36,2.636363636,0.805555556,2.272727273,0.694444444,,25,N,N,,,144,NORMAL,29,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,4/27/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,4,0.5,3.4,5.4,1.323529412,0.833333333,1.176470588,0.740740741,,3.6,N,N,,,188,NORMAL,4.5,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,4/27/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,176,NORMAL,13.68,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,4/27/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,102,76,26,35,115,2.914285714,0.886956522,2.171428571,0.660869565,,84.5,N,N,,,172,NORMAL,102,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,4/27/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,14,4,6,43,3,0.418604651,2.333333333,0.325581395,,46.5,N,N,,,173,NORMAL,18,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 8,8,57,4/27/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,25,7,11,36,2.909090909,0.888888889,2.272727273,0.694444444,,26.5,N,N,,,174,NORMAL,32,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 12,12,85,5/25/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,,219,NORMAL,4.4,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 12,12,85,5/25/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,206,NORMAL,13.68,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 12,12,85,5/25/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,107,76,31,35,115,3.057142857,0.930434783,2.171428571,0.660869565,,89.5,N,N,,,202,NORMAL,107,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 12,12,85,5/25/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,14,8,6,43,3.666666667,0.511627907,2.333333333,0.325581395,,42.5,N,N,,,203,NORMAL,22,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 12,12,85,5/25/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,25,10,11,36,3.181818182,0.972222222,2.272727273,0.694444444,Y,29.5,N,N,,,204,NORMAL,35,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,6/22/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.7,4,0.7,3.4,5.4,1.382352941,0.87037037,1.176470588,0.740740741,,3.4,N,N,,,253,NORMAL,4.7,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,6/22/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,241,NORMAL,10.26,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,6/22/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,101,76,25,35,115,2.885714286,0.87826087,2.171428571,0.660869565,,83.5,N,N,,,237,NORMAL,101,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,6/22/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,14,5,6,43,3.166666667,0.441860465,2.333333333,0.325581395,,45.5,N,N,,,238,NORMAL,19,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 16,16,113,6/22/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,34,25,9,11,36,3.090909091,0.944444444,2.272727273,0.694444444,,28.5,N,N,,,239,NORMAL,34,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/20/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.3,4,0.3,3.4,5.4,1.264705882,0.796296296,1.176470588,0.740740741,,3.8,N,N,,,283,NORMAL,4.3,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/20/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,271,NORMAL,10.26,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/20/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,96,76,20,35,115,2.742857143,0.834782609,2.171428571,0.660869565,,78.5,N,N,,,267,NORMAL,96,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/20/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,14,8,6,43,3.666666667,0.511627907,2.333333333,0.325581395,,42.5,N,N,,,268,NORMAL,22,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 20,20,141,7/20/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,34,25,9,11,36,3.090909091,0.944444444,2.272727273,0.694444444,,28.5,N,N,,,269,NORMAL,34,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 24,24,161,8/9/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,Y,4,N,N,,Y,314,NORMAL,4.1,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,161,8/9/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,Y,4,N,N,,Y,314,NORMAL,4.1,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 24,24,161,8/9/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,Y,301,NORMAL,13.68,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,161,8/9/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,Y,301,NORMAL,13.68,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 24,24,161,8/9/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,76,16,35,115,2.628571429,0.8,2.171428571,0.660869565,,80.5,N,N,,Y,297,NORMAL,92,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,161,8/9/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,76,16,35,115,2.628571429,0.8,2.171428571,0.660869565,,80.5,N,N,,Y,297,NORMAL,92,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 24,24,161,8/9/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,14,3,6,43,2.833333333,0.395348837,2.333333333,0.325581395,,47.5,N,N,,Y,298,NORMAL,17,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,161,8/9/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,14,3,6,43,2.833333333,0.395348837,2.333333333,0.325581395,,47.5,N,N,,Y,298,NORMAL,17,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 24,24,161,8/9/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,25,6,11,36,2.818181818,0.861111111,2.272727273,0.694444444,,25.5,N,N,,Y,299,NORMAL,31,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y,End of Treatment,99,161,8/9/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,25,6,11,36,2.818181818,0.861111111,2.272727273,0.694444444,,25.5,N,N,,Y,299,NORMAL,31,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 26,26,183,8/31/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,348,NORMAL,4.1,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 26,26,183,8/31/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,336,NORMAL,10.26,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 26,26,183,8/31/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,76,17,35,115,2.657142857,0.808695652,2.171428571,0.660869565,,79.5,N,N,,,332,NORMAL,93,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 26,26,183,8/31/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,31,14,17,6,43,5.166666667,0.720930233,2.333333333,0.325581395,,33.5,N,N,,,333,NORMAL,31,0,No
CDISCPILOT01,1042,01-703-1042,Placebo,0,Placebo,0,3/2/13,8/31/13,64,<65,1,WHITE,1,M,Y,,Y, Week 26,26,183,8/31/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,38,25,13,11,36,3.454545455,1.055555556,2.272727273,0.694444444,,32.5,N,N,,,334,HIGH,38,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-9,10/16/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.7,4.7,,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,Y,,19,NORMAL,4.7,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-9,10/16/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-9,10/16/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,81,,35,115,2.314285714,0.704347826,2.314285714,0.704347826,,91.5,N,N,Y,,2,NORMAL,81,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-9,10/16/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,35,3.166666667,0.542857143,3.166666667,0.542857143,,33.5,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-9,10/16/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,Y,,4,NORMAL,24,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,13,11/6/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,4.7,-0.4,3.4,5.4,1.264705882,0.796296296,1.382352941,0.87037037,Y,3.8,N,N,,,56,NORMAL,4.3,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,13,11/6/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,13,11/6/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,81,-1,35,115,2.285714286,0.695652174,2.314285714,0.704347826,,92.5,N,N,,,39,NORMAL,80,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,13,11/6/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,19,3,6,35,3.666666667,0.628571429,3.166666667,0.542857143,,30.5,N,N,,,40,NORMAL,22,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,13,11/6/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,,41,NORMAL,23,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/20/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.7,4.7,0,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,,,90,NORMAL,4.7,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/20/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/20/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,81,0,35,115,2.314285714,0.704347826,2.314285714,0.704347826,,91.5,N,N,,,74,NORMAL,81,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/20/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,19,5,6,35,4,0.685714286,3.166666667,0.542857143,,28.5,N,N,,,75,NORMAL,24,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/20/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,24,0,11,36,2.181818182,0.666666667,2.181818182,0.666666667,,30,N,N,,,76,NORMAL,24,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,41,12/4/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.7,-0.3,3.4,5.4,1.294117647,0.814814815,1.382352941,0.87037037,,3.7,N,N,,,120,NORMAL,4.4,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,41,12/4/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,Y,24.66,N,N,,,108,NORMAL,6.84,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,41,12/4/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,81,-12,35,115,1.971428571,0.6,2.314285714,0.704347826,Y,103.5,N,N,,,104,NORMAL,69,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,41,12/4/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,19,8,6,35,4.5,0.771428571,3.166666667,0.542857143,,25.5,N,N,,,105,NORMAL,27,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,41,12/4/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,24,3,11,36,2.454545455,0.75,2.181818182,0.666666667,,27,N,N,,,106,NORMAL,27,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,54,12/17/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.6,4.7,-0.1,3.4,5.4,1.352941176,0.851851852,1.382352941,0.87037037,,3.5,N,N,,,150,NORMAL,4.6,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,54,12/17/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,54,12/17/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,81,-6,35,115,2.142857143,0.652173913,2.314285714,0.704347826,,97.5,N,N,,,134,NORMAL,75,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,54,12/17/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,19,7,6,35,4.333333333,0.742857143,3.166666667,0.542857143,,26.5,N,N,,,135,NORMAL,26,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,54,12/17/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,24,-1,11,36,2.090909091,0.638888889,2.181818182,0.666666667,,31,N,N,,,136,NORMAL,23,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,61,12/24/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.7,-0.3,3.4,5.4,1.294117647,0.814814815,1.382352941,0.87037037,,3.7,N,N,,Y,181,NORMAL,4.4,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,61,12/24/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4.7,-0.3,3.4,5.4,1.294117647,0.814814815,1.382352941,0.87037037,,3.7,N,N,,Y,181,NORMAL,4.4,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,61,12/24/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,Y,168,NORMAL,6.84,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,61,12/24/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,Y,168,NORMAL,6.84,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,61,12/24/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,81,-4,35,115,2.2,0.669565217,2.314285714,0.704347826,,95.5,N,N,,Y,164,NORMAL,77,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,61,12/24/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,81,-4,35,115,2.2,0.669565217,2.314285714,0.704347826,,95.5,N,N,,Y,164,NORMAL,77,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,61,12/24/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,19,1,6,35,3.333333333,0.571428571,3.166666667,0.542857143,Y,32.5,N,N,,Y,165,NORMAL,20,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,61,12/24/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,19,1,6,35,3.333333333,0.571428571,3.166666667,0.542857143,Y,32.5,N,N,,Y,165,NORMAL,20,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,61,12/24/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,24,-3,11,36,1.909090909,0.583333333,2.181818182,0.666666667,Y,33,N,N,,Y,166,NORMAL,21,0,No
CDISCPILOT01,1076,01-703-1076,Xanomeline High Dose,81,Xanomeline High Dose,81,10/25/13,12/24/13,69,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,61,12/24/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,24,-3,11,36,1.909090909,0.583333333,2.181818182,0.666666667,Y,33,N,N,,Y,166,NORMAL,21,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,8/19/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,15,NORMAL,4.6,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,8/19/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,5,NORMAL,11.97,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,8/19/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,50,,35,115,1.428571429,0.434782609,1.428571429,0.434782609,,122.5,N,N,Y,,2,NORMAL,50,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,8/19/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,20,,6,35,3.333333333,0.571428571,3.333333333,0.571428571,,32.5,N,N,Y,,3,NORMAL,20,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,8/19/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,32,,11,36,2.909090909,0.888888889,2.909090909,0.888888889,,26.5,N,N,Y,,4,NORMAL,32,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,9/16/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,56,NORMAL,4.4,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,9/16/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,Y,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,9/16/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,50,11,35,115,1.742857143,0.530434783,1.428571429,0.434782609,,111.5,N,N,,,39,NORMAL,61,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,9/16/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,20,9,6,35,4.833333333,0.828571429,3.333333333,0.571428571,,26,N,N,,,40,NORMAL,29,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,9/16/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,40,32,8,11,36,3.636363636,1.111111111,2.909090909,0.888888889,Y,34.5,N,N,,,41,HIGH,40,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,31,10/2/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,Y,3.8,N,N,,,90,NORMAL,4.3,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,31,10/2/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,,78,NORMAL,11.97,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,31,10/2/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,50,11,35,115,1.742857143,0.530434783,1.428571429,0.434782609,,111.5,N,N,,,74,NORMAL,61,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,31,10/2/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,20,-3,6,35,2.833333333,0.485714286,3.333333333,0.571428571,,35.5,N,N,,,75,NORMAL,17,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,31,10/2/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,32,-7,11,36,2.272727273,0.694444444,2.909090909,0.888888889,,29,N,N,,,76,NORMAL,25,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,10/13/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,5,4.6,0.4,3.4,5.4,1.470588235,0.925925926,1.352941176,0.851851852,,3.3,N,N,,,120,NORMAL,5,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,10/13/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,,108,NORMAL,11.97,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,10/13/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,50,12,35,115,1.771428571,0.539130435,1.428571429,0.434782609,,110.5,N,N,,,104,NORMAL,62,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,10/13/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,20,-7,6,35,2.166666667,0.371428571,3.333333333,0.571428571,,39.5,N,N,,,105,NORMAL,13,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,10/13/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,32,-8,11,36,2.181818182,0.666666667,2.909090909,0.888888889,,30,N,N,,,106,NORMAL,24,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,56,10/27/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.9,4.6,0.3,3.4,5.4,1.441176471,0.907407407,1.352941176,0.851851852,,3.2,N,N,,,150,NORMAL,4.9,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,56,10/27/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,138,NORMAL,10.26,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,56,10/27/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,50,22,35,115,2.057142857,0.626086957,1.428571429,0.434782609,,100.5,N,N,,,134,NORMAL,72,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,56,10/27/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,20,-4,6,35,2.666666667,0.457142857,3.333333333,0.571428571,,36.5,N,N,,,135,NORMAL,16,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,56,10/27/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,32,-6,11,36,2.363636364,0.722222222,2.909090909,0.888888889,,28,N,N,,,136,NORMAL,26,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,87,11/27/12,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,181,NORMAL,4.5,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,87,11/27/12,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,168,NORMAL,10.26,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,87,11/27/12,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,50,3,35,115,1.514285714,0.460869565,1.428571429,0.434782609,Y,119.5,N,N,,,164,NORMAL,53,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,87,11/27/12,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,20,-8,6,35,2,0.342857143,3.333333333,0.571428571,Y,40.5,N,N,,,165,NORMAL,12,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,87,11/27/12,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,32,-1,11,36,2.818181818,0.861111111,2.909090909,0.888888889,,25.5,N,N,,,166,NORMAL,31,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,114,12/24/12,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,Y,216,NORMAL,4.4,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,114,12/24/12,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,Y,216,NORMAL,4.4,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,114,12/24/12,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,15.39,11.97,3.42,3,21,5.13,0.732857143,3.99,0.57,,16.11,N,N,,Y,203,NORMAL,15.39,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,114,12/24/12,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,15.39,11.97,3.42,3,21,5.13,0.732857143,3.99,0.57,,16.11,N,N,,Y,203,NORMAL,15.39,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,114,12/24/12,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,50,3,35,115,1.514285714,0.460869565,1.428571429,0.434782609,,119.5,N,N,,Y,199,NORMAL,53,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,114,12/24/12,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,50,3,35,115,1.514285714,0.460869565,1.428571429,0.434782609,,119.5,N,N,,Y,199,NORMAL,53,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,114,12/24/12,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,20,5,6,35,4.166666667,0.714285714,3.333333333,0.571428571,,27.5,N,N,,Y,200,NORMAL,25,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,114,12/24/12,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,20,5,6,35,4.166666667,0.714285714,3.333333333,0.571428571,,27.5,N,N,,Y,200,NORMAL,25,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,114,12/24/12,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,32,-2,11,36,2.727272727,0.833333333,2.909090909,0.888888889,,24.5,N,N,,Y,201,NORMAL,30,0,No
CDISCPILOT01,1086,01-703-1086,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/2/12,12/4/12,71,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,114,12/24/12,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,32,-2,11,36,2.727272727,0.833333333,2.909090909,0.888888889,,24.5,N,N,,Y,201,NORMAL,30,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Baseline,0,-51,12/5/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.8,4.8,,3.4,5.4,1.411764706,0.888888889,1.411764706,0.888888889,,3.3,N,N,Y,,19,NORMAL,4.8,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Baseline,0,-51,12/5/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Baseline,0,-51,12/5/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,98,,35,115,2.8,0.852173913,2.8,0.852173913,,80.5,N,N,Y,,2,NORMAL,98,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Baseline,0,-51,12/5/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,12,,6,32,2,0.375,2,0.375,,36,N,N,Y,,3,NORMAL,12,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Baseline,0,-51,12/5/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, .,,-2,1/23/13,UNSCHEDULED 1.3,1.3,Potassium (mmol/L),K,19,CHEM,4.9,4.8,0.1,3.4,5.4,1.441176471,0.907407407,1.411764706,0.888888889,,3.2,N,N,,,68,NORMAL,4.9,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, .,,-2,1/23/13,UNSCHEDULED 1.3,1.3,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,,26.37,N,N,,,55,NORMAL,5.13,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, .,,-2,1/23/13,UNSCHEDULED 1.3,1.3,Alkaline Phosphatase (U/L),ALP,22,CHEM,87,98,-11,35,115,2.485714286,0.756521739,2.8,0.852173913,,85.5,N,N,,,51,NORMAL,87,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, .,,-2,1/23/13,UNSCHEDULED 1.3,1.3,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,12,-1,6,32,1.833333333,0.34375,2,0.375,,37,N,N,,,52,NORMAL,11,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, .,,-2,1/23/13,UNSCHEDULED 1.3,1.3,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,53,NORMAL,17,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 2,2,16,2/9/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.8,-0.2,3.4,5.4,1.352941176,0.851851852,1.411764706,0.888888889,Y,3.5,N,N,,,94,NORMAL,4.6,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 2,2,16,2/9/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,98,-9,35,115,2.542857143,0.773913043,2.8,0.852173913,Y,83.5,N,N,,,87,NORMAL,89,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,2/23/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.8,-0.2,3.4,5.4,1.352941176,0.851851852,1.411764706,0.888888889,,3.5,N,N,,Y,115,NORMAL,4.6,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,30,2/23/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.8,-0.2,3.4,5.4,1.352941176,0.851851852,1.411764706,0.888888889,,3.5,N,N,,Y,115,NORMAL,4.6,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,2/23/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,Y,104,NORMAL,6.84,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,30,2/23/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,Y,104,NORMAL,6.84,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,2/23/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,98,-8,35,115,2.571428571,0.782608696,2.8,0.852173913,,82.5,N,N,,Y,100,NORMAL,90,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,30,2/23/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,98,-8,35,115,2.571428571,0.782608696,2.8,0.852173913,,82.5,N,N,,Y,100,NORMAL,90,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,2/23/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,12,-2,6,32,1.666666667,0.3125,2,0.375,Y,38,N,N,,Y,101,NORMAL,10,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,30,2/23/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,12,-2,6,32,1.666666667,0.3125,2,0.375,Y,38,N,N,,Y,101,NORMAL,10,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y, Week 4,4,30,2/23/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,9,34,2,0.529411765,2.222222222,0.588235294,Y,33,N,N,,Y,102,NORMAL,18,0,No
CDISCPILOT01,1096,01-703-1096,Placebo,0,Placebo,0,1/25/13,3/16/13,81,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,30,2/23/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,9,34,2,0.529411765,2.222222222,0.588235294,Y,33,N,N,,Y,102,NORMAL,18,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-90,12/13/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,15,NORMAL,4.3,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-90,12/13/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,5,NORMAL,6.84,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-90,12/13/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,94,94,,35,115,2.685714286,0.817391304,2.685714286,0.817391304,,78.5,N,N,Y,,2,NORMAL,94,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-90,12/13/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,11,,6,32,1.833333333,0.34375,1.833333333,0.34375,,37,N,N,Y,,3,NORMAL,11,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-90,12/13/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,29,,9,34,3.222222222,0.852941176,3.222222222,0.852941176,,24.5,N,N,Y,,4,NORMAL,29,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, .,,-13,2/28/13,UNSCHEDULED 1.2,1.2,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,,4.2,N,N,,,57,NORMAL,3.9,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, .,,-13,2/28/13,UNSCHEDULED 1.2,1.2,Bilirubin (umol/L),BILI,21,CHEM,13.68,6.84,6.84,3,21,4.56,0.651428571,2.28,0.325714286,,17.82,N,N,,,44,NORMAL,13.68,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, .,,-13,2/28/13,UNSCHEDULED 1.2,1.2,Alkaline Phosphatase (U/L),ALP,22,CHEM,94,94,0,35,115,2.685714286,0.817391304,2.685714286,0.817391304,,78.5,N,N,,,40,NORMAL,94,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, .,,-13,2/28/13,UNSCHEDULED 1.2,1.2,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,11,7,6,32,3,0.5625,1.833333333,0.34375,,30,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, .,,-13,2/28/13,UNSCHEDULED 1.2,1.2,Aspartate Aminotransferase (U/L),AST,25,CHEM,33,29,4,9,34,3.666666667,0.970588235,3.222222222,0.852941176,,28.5,N,N,,,42,NORMAL,33,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,3/29/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,,94,NORMAL,4.5,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,3/29/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,81,NORMAL,6.84,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,3/29/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,97,94,3,35,115,2.771428571,0.843478261,2.685714286,0.817391304,,79.5,N,N,,,77,NORMAL,97,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,3/29/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,11,6,6,32,2.833333333,0.53125,1.833333333,0.34375,,31,N,N,,,78,NORMAL,17,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,3/29/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,29,2,9,34,3.444444444,0.911764706,3.222222222,0.852941176,,26.5,N,N,,,79,NORMAL,31,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,31,4/12/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,,128,NORMAL,4.5,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,31,4/12/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,116,NORMAL,8.55,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,31,4/12/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,101,94,7,35,115,2.885714286,0.87826087,2.685714286,0.817391304,,83.5,N,N,,,112,NORMAL,101,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,31,4/12/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,11,-1,6,32,1.666666667,0.3125,1.833333333,0.34375,Y,38,N,N,,,113,NORMAL,10,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,31,4/12/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,29,-3,9,34,2.888888889,0.764705882,3.222222222,0.852941176,,25,N,N,,,114,NORMAL,26,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,4/24/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,,158,NORMAL,4.4,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,4/24/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,146,NORMAL,8.55,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,4/24/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,99,94,5,35,115,2.828571429,0.860869565,2.685714286,0.817391304,,81.5,N,N,,,142,NORMAL,99,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,4/24/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,11,-1,6,32,1.666666667,0.3125,1.833333333,0.34375,,38,N,N,,,143,NORMAL,10,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,4/24/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,29,-6,9,34,2.555555556,0.676470588,3.222222222,0.852941176,Y,28,N,N,,,144,NORMAL,23,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,5/8/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.7,4.3,0.4,3.4,5.4,1.382352941,0.87037037,1.264705882,0.796296296,,3.4,N,N,,,188,NORMAL,4.7,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,5/8/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,176,NORMAL,8.55,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,5/8/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,94,-2,35,115,2.628571429,0.8,2.685714286,0.817391304,,80.5,N,N,,,172,NORMAL,92,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,5/8/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,11,0,6,32,1.833333333,0.34375,1.833333333,0.34375,,37,N,N,,,173,NORMAL,11,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,5/8/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,29,-5,9,34,2.666666667,0.705882353,3.222222222,0.852941176,,27,N,N,,,174,NORMAL,24,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,6/5/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.8,4.3,0.5,3.4,5.4,1.411764706,0.888888889,1.264705882,0.796296296,,3.3,N,N,,,219,NORMAL,4.8,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,6/5/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,206,NORMAL,6.84,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,6/5/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,102,94,8,35,115,2.914285714,0.886956522,2.685714286,0.817391304,,84.5,N,N,,,202,NORMAL,102,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,6/5/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,11,1,6,32,2,0.375,1.833333333,0.34375,,36,N,N,,,203,NORMAL,12,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,6/5/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,29,-2,9,34,3,0.794117647,3.222222222,0.852941176,,24,N,N,,,204,NORMAL,27,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,7/3/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,253,NORMAL,4.3,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,7/3/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,241,NORMAL,8.55,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,7/3/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,94,-8,35,115,2.457142857,0.747826087,2.685714286,0.817391304,,86.5,N,N,,,237,NORMAL,86,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,7/3/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,11,0,6,32,1.833333333,0.34375,1.833333333,0.34375,,37,N,N,,,238,NORMAL,11,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,7/3/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,29,0,9,34,3.222222222,0.852941176,3.222222222,0.852941176,,24.5,N,N,,,239,NORMAL,29,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,7/31/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.3,-0.1,3.4,5.4,1.235294118,0.777777778,1.264705882,0.796296296,Y,3.9,N,N,,,283,NORMAL,4.2,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,7/31/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,Y,26.37,N,N,,,271,NORMAL,5.13,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,7/31/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,94,-3,35,115,2.6,0.791304348,2.685714286,0.817391304,,81.5,N,N,,,267,NORMAL,91,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,7/31/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,11,-1,6,32,1.666666667,0.3125,1.833333333,0.34375,,38,N,N,,,268,NORMAL,10,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,7/31/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,29,-4,9,34,2.777777778,0.735294118,3.222222222,0.852941176,,26,N,N,,,269,NORMAL,25,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,169,8/28/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,Y,314,NORMAL,4.4,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,169,8/28/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,Y,314,NORMAL,4.4,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,169,8/28/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,301,NORMAL,8.55,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,169,8/28/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,301,NORMAL,8.55,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,169,8/28/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,94,11,35,115,3,0.913043478,2.685714286,0.817391304,Y,87.5,N,N,,Y,297,NORMAL,105,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,169,8/28/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,94,11,35,115,3,0.913043478,2.685714286,0.817391304,Y,87.5,N,N,,Y,297,NORMAL,105,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,169,8/28/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,11,1,6,32,2,0.375,1.833333333,0.34375,,36,N,N,,Y,298,NORMAL,12,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,169,8/28/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,11,1,6,32,2,0.375,1.833333333,0.34375,,36,N,N,,Y,298,NORMAL,12,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,169,8/28/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,29,-6,9,34,2.555555556,0.676470588,3.222222222,0.852941176,,28,N,N,,Y,299,NORMAL,23,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,169,8/28/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,29,-6,9,34,2.555555556,0.676470588,3.222222222,0.852941176,,28,N,N,,Y,299,NORMAL,23,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,186,9/14/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,,348,NORMAL,4.1,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,186,9/14/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,336,NORMAL,6.84,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,186,9/14/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,106,94,12,35,115,3.028571429,0.92173913,2.685714286,0.817391304,,88.5,N,N,,,332,NORMAL,106,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,186,9/14/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,11,-2,6,32,1.5,0.28125,1.833333333,0.34375,,39,N,N,,,333,NORMAL,9,0,No
CDISCPILOT01,1100,01-703-1100,Placebo,0,Placebo,0,3/13/13,9/14/13,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,186,9/14/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,29,-6,9,34,2.555555556,0.676470588,3.222222222,0.852941176,,28,N,N,,,334,NORMAL,23,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, .,,-6,2/14/13,UNSCHEDULED 1.3,1.3,Potassium (mmol/L),K,19,CHEM,4.5,,,3.4,5.4,1.323529412,0.833333333,,,,3.6,N,,,,21,NORMAL,4.5,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, .,,-6,2/14/13,UNSCHEDULED 1.3,1.3,Bilirubin (umol/L),BILI,21,CHEM,6.84,,,3,21,2.28,0.325714286,,,,24.66,N,,,,8,NORMAL,6.84,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, .,,-6,2/14/13,UNSCHEDULED 1.3,1.3,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,,,35,115,2.314285714,0.704347826,,,,91.5,N,,,,4,NORMAL,81,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, .,,-6,2/14/13,UNSCHEDULED 1.3,1.3,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,,,6,32,3.333333333,0.625,,,,28,N,,,,5,NORMAL,20,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, .,,-6,2/14/13,UNSCHEDULED 1.3,1.3,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,,,9,34,3.444444444,0.911764706,,,,26.5,N,,,,6,NORMAL,31,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,19,3/10/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.9,,,3.4,5.4,1.441176471,0.907407407,,,,3.2,N,,,,57,NORMAL,4.9,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,19,3/10/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,,,3,21,2.28,0.325714286,,,,24.66,N,,,,44,NORMAL,6.84,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,19,3/10/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,,,35,115,1.8,0.547826087,,,Y,109.5,N,,,,40,NORMAL,63,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,19,3/10/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,,,6,32,3.833333333,0.71875,,,,25,N,,,,41,NORMAL,23,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,19,3/10/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,33,,,9,34,3.666666667,0.970588235,,,,28.5,N,,,,42,NORMAL,33,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,30,3/21/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.9,,,3.4,5.4,1.441176471,0.907407407,,,,3.2,N,,,,91,NORMAL,4.9,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,30,3/21/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,,,3,21,2.28,0.325714286,,,,24.66,N,,,,79,NORMAL,6.84,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,30,3/21/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,,,35,115,1.971428571,0.6,,,,103.5,N,,,,75,NORMAL,69,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,30,3/21/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,,,6,32,4,0.75,,,,24,N,,,,76,NORMAL,24,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,30,3/21/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,40,,,9,34,4.444444444,1.176470588,,,,35.5,N,,,,77,HIGH,40,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 6,6,44,4/4/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.7,,,3.4,5.4,1.382352941,0.87037037,,,,3.4,N,,,,121,NORMAL,4.7,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 6,6,44,4/4/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,,,3,21,2.85,0.407142857,,,,22.95,N,,,,109,NORMAL,8.55,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 6,6,44,4/4/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,,,35,115,1.857142857,0.565217391,,,,107.5,N,,,,105,NORMAL,65,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 6,6,44,4/4/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,,,6,32,3.333333333,0.625,,,,28,N,,,,106,NORMAL,20,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 6,6,44,4/4/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,,,9,34,3.222222222,0.852941176,,,,24.5,N,,,,107,NORMAL,29,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 8,8,59,4/19/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,,,3.4,5.4,1.323529412,0.833333333,,,Y,3.6,N,,,,151,NORMAL,4.5,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 8,8,59,4/19/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,,,3,21,2.28,0.325714286,,,,24.66,N,,,,139,NORMAL,6.84,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 8,8,59,4/19/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,,,35,115,2,0.608695652,,,,102.5,N,,,,135,NORMAL,70,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 8,8,59,4/19/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,,,6,32,4.5,0.84375,,,,24,N,,,,136,NORMAL,27,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 8,8,59,4/19/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,34,,,9,34,3.777777778,1,,,,29.5,N,,,,137,NORMAL,34,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 12,12,87,5/17/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.7,,,3.4,5.4,1.382352941,0.87037037,,,,3.4,N,,,,182,NORMAL,4.7,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 12,12,87,5/17/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,5.13,,,3,21,1.71,0.244285714,,,Y,26.37,N,,,,169,NORMAL,5.13,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 12,12,87,5/17/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,,,35,115,2.314285714,0.704347826,,,,91.5,N,,,,165,NORMAL,81,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 12,12,87,5/17/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,44,,,6,32,7.333333333,1.375,,,Y,41,N,,,,166,HIGH,44,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 12,12,87,5/17/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,48,,,9,34,5.333333333,1.411764706,,,Y,43.5,N,,,,167,HIGH,48,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 16,16,114,6/13/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.7,,,3.4,5.4,1.382352941,0.87037037,,,,3.4,N,,,Y,217,NORMAL,4.7,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,114,6/13/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.7,,,3.4,5.4,1.382352941,0.87037037,,,,3.4,N,,,Y,217,NORMAL,4.7,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 16,16,114,6/13/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,,,3,21,2.28,0.325714286,,,,24.66,N,,,Y,204,NORMAL,6.84,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,114,6/13/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,,,3,21,2.28,0.325714286,,,,24.66,N,,,Y,204,NORMAL,6.84,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 16,16,114,6/13/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,,,35,115,2.114285714,0.643478261,,,,98.5,N,,,Y,200,NORMAL,74,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,114,6/13/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,,,35,115,2.114285714,0.643478261,,,,98.5,N,,,Y,200,NORMAL,74,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 16,16,114,6/13/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,,,6,32,3,0.5625,,,,30,N,,,Y,201,NORMAL,18,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,114,6/13/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,,,6,32,3,0.5625,,,,30,N,,,Y,201,NORMAL,18,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 16,16,114,6/13/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,,,9,34,3.111111111,0.823529412,,,,23.5,N,,,Y,202,NORMAL,28,0,No
CDISCPILOT01,1119,01-703-1119,Xanomeline Low Dose,54,Xanomeline Low Dose,54,2/20/13,6/13/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,114,6/13/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,,,9,34,3.111111111,0.823529412,,,,23.5,N,,,Y,202,NORMAL,28,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-10,12/10/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-10,12/10/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-10,12/10/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,83,,35,115,2.371428571,0.72173913,2.371428571,0.72173913,,89.5,N,N,Y,,2,NORMAL,83,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-10,12/10/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,35,3.166666667,0.542857143,3.166666667,0.542857143,,33.5,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-10,12/10/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,,11,36,1.545454545,0.472222222,1.545454545,0.472222222,,37,N,N,Y,,4,NORMAL,17,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Week 2,2,12,12/31/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,3.9,0.3,3.4,5.4,1.235294118,0.777777778,1.147058824,0.722222222,Y,3.9,N,N,,Y,55,NORMAL,4.2,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,12,12/31/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,3.9,0.3,3.4,5.4,1.235294118,0.777777778,1.147058824,0.722222222,Y,3.9,N,N,,Y,55,NORMAL,4.2,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Week 2,2,12,12/31/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,13.68,-1.71,3,21,3.99,0.57,4.56,0.651428571,Y,19.53,N,N,,Y,43,NORMAL,11.97,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,12,12/31/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,13.68,-1.71,3,21,3.99,0.57,4.56,0.651428571,Y,19.53,N,N,,Y,43,NORMAL,11.97,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Week 2,2,12,12/31/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,87,83,4,35,115,2.485714286,0.756521739,2.371428571,0.72173913,Y,85.5,N,N,,Y,39,NORMAL,87,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,12,12/31/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,87,83,4,35,115,2.485714286,0.756521739,2.371428571,0.72173913,Y,85.5,N,N,,Y,39,NORMAL,87,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Week 2,2,12,12/31/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,19,-6,6,35,2.166666667,0.371428571,3.166666667,0.542857143,Y,39.5,N,N,,Y,40,NORMAL,13,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,12,12/31/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,19,-6,6,35,2.166666667,0.371428571,3.166666667,0.542857143,Y,39.5,N,N,,Y,40,NORMAL,13,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y, Week 2,2,12,12/31/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,17,-1,11,36,1.454545455,0.444444444,1.545454545,0.472222222,Y,38,N,N,,Y,41,NORMAL,16,0,No
CDISCPILOT01,1175,01-703-1175,Placebo,0,Placebo,0,12/20/13,12/26/13,75,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,12,12/31/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,17,-1,11,36,1.454545455,0.444444444,1.545454545,0.472222222,Y,38,N,N,,Y,41,NORMAL,16,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-16,10/1/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.4,4.4,,3.4,5.4,1.294117647,0.814814815,1.294117647,0.814814815,,3.7,N,N,Y,,19,NORMAL,4.4,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-16,10/1/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,17.1,17.1,,3,21,5.7,0.814285714,5.7,0.814285714,,15.6,N,N,Y,,6,NORMAL,17.1,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-16,10/1/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,84,,35,115,2.4,0.730434783,2.4,0.730434783,,88.5,N,N,Y,,2,NORMAL,84,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-16,10/1/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,35,2.666666667,0.457142857,2.666666667,0.457142857,,36.5,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-16,10/1/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,Y,,4,NORMAL,21,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/31/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.7,4.4,-0.7,3.4,5.4,1.088235294,0.685185185,1.294117647,0.814814815,Y,4.4,N,N,,,56,NORMAL,3.7,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/31/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,17.1,-5.13,3,21,3.99,0.57,5.7,0.814285714,Y,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/31/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,84,-5,35,115,2.257142857,0.686956522,2.4,0.730434783,Y,93.5,N,N,,,39,NORMAL,79,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/31/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,16,-4,6,35,2,0.342857143,2.666666667,0.457142857,Y,40.5,N,N,,,40,NORMAL,12,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/31/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,21,-2,11,36,1.727272727,0.527777778,1.909090909,0.583333333,Y,35,N,N,,,41,NORMAL,19,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,34,11/19/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.2,4.4,-0.2,3.4,5.4,1.235294118,0.777777778,1.294117647,0.814814815,,3.9,N,N,,,90,NORMAL,4.2,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,34,11/19/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,17.1,-3.42,3,21,4.56,0.651428571,5.7,0.814285714,,17.82,N,N,,,78,NORMAL,13.68,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,34,11/19/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,84,-4,35,115,2.285714286,0.695652174,2.4,0.730434783,,92.5,N,N,,,74,NORMAL,80,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,34,11/19/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,16,3,6,35,3.166666667,0.542857143,2.666666667,0.457142857,,33.5,N,N,,,75,NORMAL,19,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,34,11/19/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,21,1,11,36,2,0.611111111,1.909090909,0.583333333,,32,N,N,,,76,NORMAL,22,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,43,11/28/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4,4.4,-0.4,3.4,5.4,1.176470588,0.740740741,1.294117647,0.814814815,,4.1,N,N,,,120,NORMAL,4,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,43,11/28/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,11.97,17.1,-5.13,3,21,3.99,0.57,5.7,0.814285714,,19.53,N,N,,,108,NORMAL,11.97,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,43,11/28/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,84,7,35,115,2.6,0.791304348,2.4,0.730434783,,81.5,N,N,,,104,NORMAL,91,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,43,11/28/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,35,2.5,0.428571429,2.666666667,0.457142857,,37.5,N,N,,,105,NORMAL,15,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,43,11/28/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,21,2,11,36,2.090909091,0.638888889,1.909090909,0.583333333,,31,N,N,,,106,NORMAL,23,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,57,12/12/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.9,4.4,0.5,3.4,5.4,1.441176471,0.907407407,1.294117647,0.814814815,,3.2,N,N,,Y,151,NORMAL,4.9,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,57,12/12/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.9,4.4,0.5,3.4,5.4,1.441176471,0.907407407,1.294117647,0.814814815,,3.2,N,N,,Y,151,NORMAL,4.9,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,57,12/12/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,13.68,17.1,-3.42,3,21,4.56,0.651428571,5.7,0.814285714,,17.82,N,N,,Y,138,NORMAL,13.68,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,57,12/12/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,13.68,17.1,-3.42,3,21,4.56,0.651428571,5.7,0.814285714,,17.82,N,N,,Y,138,NORMAL,13.68,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,57,12/12/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,84,-1,35,115,2.371428571,0.72173913,2.4,0.730434783,,89.5,N,N,,Y,134,NORMAL,83,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,57,12/12/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,84,-1,35,115,2.371428571,0.72173913,2.4,0.730434783,,89.5,N,N,,Y,134,NORMAL,83,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,57,12/12/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,35,2.5,0.428571429,2.666666667,0.457142857,,37.5,N,N,,Y,135,NORMAL,15,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,57,12/12/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,35,2.5,0.428571429,2.666666667,0.457142857,,37.5,N,N,,Y,135,NORMAL,15,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,57,12/12/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,21,1,11,36,2,0.611111111,1.909090909,0.583333333,,32,N,N,,Y,136,NORMAL,22,0,No
CDISCPILOT01,1182,01-703-1182,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/17/13,12/11/13,84,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,57,12/12/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,21,1,11,36,2,0.611111111,1.909090909,0.583333333,,32,N,N,,Y,136,NORMAL,22,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-101,3/7/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-101,3/7/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-101,3/7/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,69,,35,115,1.971428571,0.6,1.971428571,0.6,,103.5,N,N,Y,,2,NORMAL,69,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-101,3/7/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,18,,6,32,3,0.5625,3,0.5625,,30,N,N,Y,,3,NORMAL,18,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-101,3/7/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,,9,34,2.333333333,0.617647059,2.333333333,0.617647059,,30,N,N,Y,,4,NORMAL,21,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-15,6/1/13,UNSCHEDULED 1.1,1.1,Potassium (mmol/L),K,19,CHEM,4,3.9,0.1,3.4,5.4,1.176470588,0.740740741,1.147058824,0.722222222,,4.1,N,N,,,56,NORMAL,4,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-15,6/1/13,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-15,6/1/13,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,69,6,35,115,2.142857143,0.652173913,1.971428571,0.6,,97.5,N,N,,,39,NORMAL,75,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-15,6/1/13,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,18,0,6,32,3,0.5625,3,0.5625,,30,N,N,,,40,NORMAL,18,0,No
CDISCPILOT01,1197,01-703-1197,Xanomeline Low Dose,54,Xanomeline Low Dose,54,6/16/13,6/29/13,76,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-15,6/1/13,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,21,-4,9,34,1.888888889,0.5,2.333333333,0.617647059,,34,N,N,,,41,NORMAL,17,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-16,2/28/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.6,3.6,,3.4,5.4,1.058823529,0.666666667,1.058823529,0.666666667,,4.5,N,N,Y,,19,NORMAL,3.6,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-16,2/28/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-16,2/28/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,83,,35,115,2.371428571,0.72173913,2.371428571,0.72173913,,89.5,N,N,Y,,2,NORMAL,83,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-16,2/28/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,32,2.666666667,0.5,2.666666667,0.5,,32,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-16,2/28/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,Y,,4,NORMAL,25,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/30/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.5,3.6,-0.1,3.4,5.4,1.029411765,0.648148148,1.058823529,0.666666667,Y,4.6,N,N,,,56,NORMAL,3.5,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/30/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/30/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,83,9,35,115,2.628571429,0.8,2.371428571,0.72173913,,80.5,N,N,,,39,NORMAL,92,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/30/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,32,3,0.5625,2.666666667,0.5,,30,N,N,,,40,NORMAL,18,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/30/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,25,0,9,34,2.777777778,0.735294118,2.777777778,0.735294118,,26,N,N,,,41,NORMAL,25,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/12/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.5,3.6,-0.1,3.4,5.4,1.029411765,0.648148148,1.058823529,0.666666667,,4.6,N,N,,,90,NORMAL,3.5,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/12/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,,78,NORMAL,11.97,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/12/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,83,5,35,115,2.514285714,0.765217391,2.371428571,0.72173913,,84.5,N,N,,,74,NORMAL,88,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/12/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,32,3,0.5625,2.666666667,0.5,,30,N,N,,,75,NORMAL,18,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/12/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,25,5,9,34,3.333333333,0.882352941,2.777777778,0.735294118,,25.5,N,N,,,76,NORMAL,30,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,4/28/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.8,3.6,0.2,3.4,5.4,1.117647059,0.703703704,1.058823529,0.666666667,,4.3,N,N,,,110,NORMAL,3.8,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,4/28/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,83,-11,35,115,2.057142857,0.626086957,2.371428571,0.72173913,,100.5,N,N,,,103,NORMAL,72,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,5/10/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.8,3.6,0.2,3.4,5.4,1.117647059,0.703703704,1.058823529,0.666666667,,4.3,N,N,,,132,NORMAL,3.8,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,5/10/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,120,NORMAL,6.84,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,5/10/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,83,0,35,115,2.371428571,0.72173913,2.371428571,0.72173913,,89.5,N,N,,,116,NORMAL,83,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,5/10/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,16,-3,6,32,2.166666667,0.40625,2.666666667,0.5,Y,35,N,N,,,117,NORMAL,13,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,5/10/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,25,1,9,34,2.888888889,0.764705882,2.777777778,0.735294118,,25,N,N,,,118,NORMAL,26,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,6/7/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,3.6,0.5,3.4,5.4,1.205882353,0.759259259,1.058823529,0.666666667,,4,N,N,,,163,NORMAL,4.1,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,6/7/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,150,NORMAL,8.55,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,6/7/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,83,-10,35,115,2.085714286,0.634782609,2.371428571,0.72173913,,99.5,N,N,,,146,NORMAL,73,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,6/7/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,32,2.5,0.46875,2.666666667,0.5,,33,N,N,,,147,NORMAL,15,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,6/7/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,25,1,9,34,2.888888889,0.764705882,2.777777778,0.735294118,,25,N,N,,,148,NORMAL,26,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,7/5/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,3.6,3.6,0,3.4,5.4,1.058823529,0.666666667,1.058823529,0.666666667,,4.5,N,N,,,197,NORMAL,3.6,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,7/5/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,185,NORMAL,6.84,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,7/5/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,83,-9,35,115,2.114285714,0.643478261,2.371428571,0.72173913,,98.5,N,N,,,181,NORMAL,74,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,7/5/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,32,2.5,0.46875,2.666666667,0.5,,33,N,N,,,182,NORMAL,15,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,7/5/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,25,4,9,34,3.222222222,0.852941176,2.777777778,0.735294118,,24.5,N,N,,,183,NORMAL,29,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,134,7/27/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.6,3.6,0,3.4,5.4,1.058823529,0.666666667,1.058823529,0.666666667,,4.5,N,N,,,227,NORMAL,3.6,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,134,7/27/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,215,NORMAL,6.84,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,134,7/27/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,83,-2,35,115,2.314285714,0.704347826,2.371428571,0.72173913,,91.5,N,N,,,211,NORMAL,81,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,134,7/27/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,32,2.333333333,0.4375,2.666666667,0.5,,34,N,N,,,212,NORMAL,14,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,134,7/27/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,25,-1,9,34,2.666666667,0.705882353,2.777777778,0.735294118,Y,27,N,N,,,213,NORMAL,24,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,162,8/24/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,3.6,0.3,3.4,5.4,1.147058824,0.722222222,1.058823529,0.666666667,,4.2,N,N,,Y,258,NORMAL,3.9,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,162,8/24/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.9,3.6,0.3,3.4,5.4,1.147058824,0.722222222,1.058823529,0.666666667,,4.2,N,N,,Y,258,NORMAL,3.9,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,162,8/24/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,245,NORMAL,8.55,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,162,8/24/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,245,NORMAL,8.55,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,162,8/24/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,83,-14,35,115,1.971428571,0.6,2.371428571,0.72173913,Y,103.5,N,N,,Y,241,NORMAL,69,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,162,8/24/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,83,-14,35,115,1.971428571,0.6,2.371428571,0.72173913,Y,103.5,N,N,,Y,241,NORMAL,69,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,162,8/24/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,32,2.333333333,0.4375,2.666666667,0.5,,34,N,N,,Y,242,NORMAL,14,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,162,8/24/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,32,2.333333333,0.4375,2.666666667,0.5,,34,N,N,,Y,242,NORMAL,14,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,162,8/24/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,25,-1,9,34,2.666666667,0.705882353,2.777777778,0.735294118,,27,N,N,,Y,243,NORMAL,24,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,162,8/24/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,25,-1,9,34,2.666666667,0.705882353,2.777777778,0.735294118,,27,N,N,,Y,243,NORMAL,24,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,175,9/6/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,3.8,3.6,0.2,3.4,5.4,1.117647059,0.703703704,1.058823529,0.666666667,,4.3,N,N,,,292,NORMAL,3.8,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,175,9/6/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,280,NORMAL,6.84,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,175,9/6/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,83,-5,35,115,2.228571429,0.67826087,2.371428571,0.72173913,,94.5,N,N,,,276,NORMAL,78,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,175,9/6/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,32,2.333333333,0.4375,2.666666667,0.5,,34,N,N,,,277,NORMAL,14,0,No
CDISCPILOT01,1210,01-703-1210,Placebo,0,Placebo,0,3/16/13,9/6/13,72,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,175,9/6/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,25,-4,9,34,2.333333333,0.617647059,2.777777778,0.735294118,,30,N,N,,,278,NORMAL,21,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Baseline,0,-10,7/10/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.4,3.4,,3.4,5.4,1,0.62962963,1,0.62962963,,4.7,N,N,Y,,19,NORMAL,3.4,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Baseline,0,-10,7/10/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Baseline,0,-10,7/10/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,78,,35,115,2.228571429,0.67826087,2.228571429,0.67826087,,94.5,N,N,Y,,2,NORMAL,78,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Baseline,0,-10,7/10/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,43,43,,6,32,7.166666667,1.34375,7.166666667,1.34375,,40,N,N,Y,,3,HIGH,43,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Baseline,0,-10,7/10/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,36,36,,9,34,4,1.058823529,4,1.058823529,,31.5,N,N,Y,,4,HIGH,36,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 2,2,12,7/31/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,3.4,0.6,3.4,5.4,1.176470588,0.740740741,1,0.62962963,,4.1,N,N,,,55,NORMAL,4,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 2,2,12,7/31/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 2,2,12,7/31/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,78,0,35,115,2.228571429,0.67826087,2.228571429,0.67826087,,94.5,N,N,,,39,NORMAL,78,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 2,2,12,7/31/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,39,43,-4,6,32,6.5,1.21875,7.166666667,1.34375,Y,36,N,N,,,40,HIGH,39,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 2,2,12,7/31/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,36,-7,9,34,3.222222222,0.852941176,4,1.058823529,,24.5,N,N,,,41,NORMAL,29,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 4,4,29,8/17/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4,3.4,0.6,3.4,5.4,1.176470588,0.740740741,1,0.62962963,,4.1,N,N,,,85,NORMAL,4,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 4,4,29,8/17/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,73,NORMAL,10.26,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 4,4,29,8/17/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,78,12,35,115,2.571428571,0.782608696,2.228571429,0.67826087,,82.5,N,N,,,69,NORMAL,90,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 4,4,29,8/17/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,38,43,-5,6,32,6.333333333,1.1875,7.166666667,1.34375,,35,N,N,,,70,HIGH,38,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 4,4,29,8/17/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,33,36,-3,9,34,3.666666667,0.970588235,4,1.058823529,,28.5,N,N,,,71,NORMAL,33,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 6,6,47,9/4/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,3.4,0.8,3.4,5.4,1.235294118,0.777777778,1,0.62962963,,3.9,N,N,,,115,NORMAL,4.2,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 6,6,47,9/4/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,103,NORMAL,10.26,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 6,6,47,9/4/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,78,6,35,115,2.4,0.730434783,2.228571429,0.67826087,,88.5,N,N,,,99,NORMAL,84,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 6,6,47,9/4/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,43,-19,6,32,4,0.75,7.166666667,1.34375,,24,N,N,,,100,NORMAL,24,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 6,6,47,9/4/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,36,-13,9,34,2.555555556,0.676470588,4,1.058823529,,28,N,N,,,101,NORMAL,23,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 8,8,57,9/14/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.7,3.4,0.3,3.4,5.4,1.088235294,0.685185185,1,0.62962963,Y,4.4,N,N,,,145,NORMAL,3.7,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 8,8,57,9/14/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,133,NORMAL,10.26,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 8,8,57,9/14/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,78,5,35,115,2.371428571,0.72173913,2.228571429,0.67826087,,89.5,N,N,,,129,NORMAL,83,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 8,8,57,9/14/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,43,-18,6,32,4.166666667,0.78125,7.166666667,1.34375,,23,N,N,,,130,NORMAL,25,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 8,8,57,9/14/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,36,-11,9,34,2.777777778,0.735294118,4,1.058823529,,26,N,N,,,131,NORMAL,25,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 12,12,82,10/9/12,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,3.4,0.5,3.4,5.4,1.147058824,0.722222222,1,0.62962963,,4.2,N,N,,,176,NORMAL,3.9,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 12,12,82,10/9/12,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,10.26,-3.42,3,21,2.28,0.325714286,3.42,0.488571429,Y,24.66,N,N,,,163,NORMAL,6.84,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 12,12,82,10/9/12,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,71,78,-7,35,115,2.028571429,0.617391304,2.228571429,0.67826087,,101.5,N,N,,,159,NORMAL,71,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 12,12,82,10/9/12,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,43,-22,6,32,3.5,0.65625,7.166666667,1.34375,,27,N,N,,,160,NORMAL,21,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 12,12,82,10/9/12,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,36,-16,9,34,2.222222222,0.588235294,4,1.058823529,,31,N,N,,,161,NORMAL,20,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 16,16,109,11/5/12,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,3.8,3.4,0.4,3.4,5.4,1.117647059,0.703703704,1,0.62962963,,4.3,N,N,,,210,NORMAL,3.8,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 16,16,109,11/5/12,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,198,NORMAL,11.97,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 16,16,109,11/5/12,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,78,1,35,115,2.257142857,0.686956522,2.228571429,0.67826087,,93.5,N,N,,,194,NORMAL,79,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 16,16,109,11/5/12,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,43,-16,6,32,4.5,0.84375,7.166666667,1.34375,,24,N,N,,,195,NORMAL,27,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 16,16,109,11/5/12,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,36,-9,9,34,3,0.794117647,4,1.058823529,,24,N,N,,,196,NORMAL,27,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 20,20,137,12/3/12,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.7,3.4,0.3,3.4,5.4,1.088235294,0.685185185,1,0.62962963,,4.4,N,N,,,240,NORMAL,3.7,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 20,20,137,12/3/12,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,228,NORMAL,8.55,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 20,20,137,12/3/12,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,78,-10,35,115,1.942857143,0.591304348,2.228571429,0.67826087,Y,104.5,N,N,,,224,NORMAL,68,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 20,20,137,12/3/12,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,43,-24,6,32,3.166666667,0.59375,7.166666667,1.34375,,29,N,N,,,225,NORMAL,19,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 20,20,137,12/3/12,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,36,-17,9,34,2.111111111,0.558823529,4,1.058823529,,32,N,N,,,226,NORMAL,19,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 24,24,165,12/31/12,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,3.4,0.4,3.4,5.4,1.117647059,0.703703704,1,0.62962963,,4.3,N,N,,Y,271,NORMAL,3.8,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y,End of Treatment,99,165,12/31/12,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,3.8,3.4,0.4,3.4,5.4,1.117647059,0.703703704,1,0.62962963,,4.3,N,N,,Y,271,NORMAL,3.8,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 24,24,165,12/31/12,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,Y,258,NORMAL,11.97,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y,End of Treatment,99,165,12/31/12,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,Y,258,NORMAL,11.97,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 24,24,165,12/31/12,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,78,-8,35,115,2,0.608695652,2.228571429,0.67826087,,102.5,N,N,,Y,254,NORMAL,70,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y,End of Treatment,99,165,12/31/12,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,78,-8,35,115,2,0.608695652,2.228571429,0.67826087,,102.5,N,N,,Y,254,NORMAL,70,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 24,24,165,12/31/12,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,43,-24,6,32,3.166666667,0.59375,7.166666667,1.34375,,29,N,N,,Y,255,NORMAL,19,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y,End of Treatment,99,165,12/31/12,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,43,-24,6,32,3.166666667,0.59375,7.166666667,1.34375,,29,N,N,,Y,255,NORMAL,19,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y, Week 24,24,165,12/31/12,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,36,-18,9,34,2,0.529411765,4,1.058823529,Y,33,N,N,,Y,256,NORMAL,18,0,No
CDISCPILOT01,1258,01-703-1258,Xanomeline High Dose,81,Xanomeline High Dose,81,7/20/12,1/11/13,78,65-80,2,WHITE,1,F,Y,Y,Y,End of Treatment,99,165,12/31/12,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,36,-18,9,34,2,0.529411765,4,1.058823529,Y,33,N,N,,Y,256,NORMAL,18,0,No
CDISCPILOT01,1279,01-703-1279,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/13/13,6/3/13,72,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,4/27/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.9,4.9,,3.4,5.4,1.441176471,0.907407407,1.441176471,0.907407407,,3.2,N,N,Y,,19,NORMAL,4.9,0,No
CDISCPILOT01,1279,01-703-1279,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/13/13,6/3/13,72,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,4/27/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1279,01-703-1279,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/13/13,6/3/13,72,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,4/27/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,78,,35,115,2.228571429,0.67826087,2.228571429,0.67826087,,94.5,N,N,Y,,2,NORMAL,78,0,No
CDISCPILOT01,1279,01-703-1279,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/13/13,6/3/13,72,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,4/27/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,11,,6,32,1.833333333,0.34375,1.833333333,0.34375,,37,N,N,Y,,3,NORMAL,11,0,No
CDISCPILOT01,1279,01-703-1279,Xanomeline Low Dose,54,Xanomeline Low Dose,54,5/13/13,6/3/13,72,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-16,4/27/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,,9,34,1.888888889,0.5,1.888888889,0.5,,34,N,N,Y,,4,NORMAL,17,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Baseline,0,-28,10/24/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.7,4.7,,3.4,5.4,1.382352941,0.87037037,1.382352941,0.87037037,,3.4,N,N,Y,,19,NORMAL,4.7,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Baseline,0,-28,10/24/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Baseline,0,-28,10/24/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,386,386,,35,115,11.02857143,3.356521739,11.02857143,3.356521739,,368.5,H,H,Y,,2,HIGH,386,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Baseline,0,-28,10/24/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,12,,6,32,2,0.375,2,0.375,,36,N,N,Y,,3,NORMAL,12,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Baseline,0,-28,10/24/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,,9,34,2.333333333,0.617647059,2.333333333,0.617647059,,30,N,N,Y,,4,NORMAL,21,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, .,,-17,11/4/13,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, .,,-17,11/4/13,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,398,386,12,35,115,11.37142857,3.460869565,11.02857143,3.356521739,,380.5,H,H,,,39,HIGH,398,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, .,,-17,11/4/13,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,12,2,6,32,2.333333333,0.4375,2,0.375,,34,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, .,,-17,11/4/13,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,21,1,9,34,2.444444444,0.647058824,2.333333333,0.617647059,,29,N,N,,,41,NORMAL,22,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,12/5/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,4.7,-0.4,3.4,5.4,1.264705882,0.796296296,1.382352941,0.87037037,,3.8,N,N,,,84,NORMAL,4.3,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,12/5/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,71,NORMAL,10.26,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,12/5/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,390,386,4,35,115,11.14285714,3.391304348,11.02857143,3.356521739,Y,372.5,H,H,,,67,HIGH,390,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,12/5/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,12,7,6,32,3.166666667,0.59375,2,0.375,,29,N,N,,,68,NORMAL,19,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,12/5/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,21,-1,9,34,2.222222222,0.588235294,2.333333333,0.617647059,,31,N,N,,,69,NORMAL,20,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 4,4,28,12/18/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.2,4.7,-0.5,3.4,5.4,1.235294118,0.777777778,1.382352941,0.87037037,,3.9,N,N,,,118,NORMAL,4.2,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 4,4,28,12/18/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,106,NORMAL,10.26,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 4,4,28,12/18/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,382,386,-4,35,115,10.91428571,3.32173913,11.02857143,3.356521739,,364.5,H,H,,,102,HIGH,382,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 4,4,28,12/18/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,12,9,6,32,3.5,0.65625,2,0.375,,27,N,N,,,103,NORMAL,21,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 4,4,28,12/18/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,21,5,9,34,2.888888889,0.764705882,2.333333333,0.617647059,,25,N,N,,,104,NORMAL,26,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,1/1/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.7,-0.4,3.4,5.4,1.264705882,0.796296296,1.382352941,0.87037037,,3.8,N,N,,,148,NORMAL,4.3,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,1/1/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,,136,NORMAL,6.84,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,1/1/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,378,386,-8,35,115,10.8,3.286956522,11.02857143,3.356521739,,360.5,H,H,,,132,HIGH,378,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,1/1/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,12,2,6,32,2.333333333,0.4375,2,0.375,,34,N,N,,,133,NORMAL,14,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,1/1/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,21,-1,9,34,2.222222222,0.588235294,2.333333333,0.617647059,,31,N,N,,,134,NORMAL,20,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 8,8,56,1/15/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.9,4.7,-0.8,3.4,5.4,1.147058824,0.722222222,1.382352941,0.87037037,Y,4.2,N,N,,,178,NORMAL,3.9,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 8,8,56,1/15/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,166,NORMAL,10.26,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 8,8,56,1/15/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,372,386,-14,35,115,10.62857143,3.234782609,11.02857143,3.356521739,,354.5,H,H,,,162,HIGH,372,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 8,8,56,1/15/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,12,1,6,32,2.166666667,0.40625,2,0.375,,35,N,N,,,163,NORMAL,13,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 8,8,56,1/15/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,21,-2,9,34,2.111111111,0.558823529,2.333333333,0.617647059,,32,N,N,,,164,NORMAL,19,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 12,12,90,2/18/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4,4.7,-0.7,3.4,5.4,1.176470588,0.740740741,1.382352941,0.87037037,,4.1,N,N,,,209,NORMAL,4,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 12,12,90,2/18/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,196,NORMAL,8.55,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 12,12,90,2/18/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,375,386,-11,35,115,10.71428571,3.260869565,11.02857143,3.356521739,,357.5,H,H,,,192,HIGH,375,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 12,12,90,2/18/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,12,3,6,32,2.5,0.46875,2,0.375,,33,N,N,,,193,NORMAL,15,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 12,12,90,2/18/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,21,-2,9,34,2.111111111,0.558823529,2.333333333,0.617647059,,32,N,N,,,194,NORMAL,19,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,3/13/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.5,4.7,-0.2,3.4,5.4,1.323529412,0.833333333,1.382352941,0.87037037,,3.6,N,N,,,243,NORMAL,4.5,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,3/13/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,231,NORMAL,8.55,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,3/13/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,380,386,-6,35,115,10.85714286,3.304347826,11.02857143,3.356521739,,362.5,H,H,,,227,HIGH,380,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,3/13/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,12,7,6,32,3.166666667,0.59375,2,0.375,,29,N,N,,,228,NORMAL,19,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,3/13/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,21,5,9,34,2.888888889,0.764705882,2.333333333,0.617647059,,25,N,N,,,229,NORMAL,26,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 20,20,180,5/19/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.7,-0.5,3.4,5.4,1.235294118,0.777777778,1.382352941,0.87037037,,3.9,N,N,,Y,274,NORMAL,4.2,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,180,5/19/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4.7,-0.5,3.4,5.4,1.235294118,0.777777778,1.382352941,0.87037037,,3.9,N,N,,Y,274,NORMAL,4.2,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 20,20,180,5/19/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,261,NORMAL,8.55,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,180,5/19/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,261,NORMAL,8.55,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 20,20,180,5/19/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,361,386,-25,35,115,10.31428571,3.139130435,11.02857143,3.356521739,,343.5,H,H,,Y,257,HIGH,361,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,180,5/19/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,361,386,-25,35,115,10.31428571,3.139130435,11.02857143,3.356521739,,343.5,H,H,,Y,257,HIGH,361,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 20,20,180,5/19/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,12,-2,6,32,1.666666667,0.3125,2,0.375,Y,38,N,N,,Y,258,NORMAL,10,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,180,5/19/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,12,-2,6,32,1.666666667,0.3125,2,0.375,Y,38,N,N,,Y,258,NORMAL,10,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y, Week 20,20,180,5/19/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,21,-3,9,34,2,0.529411765,2.333333333,0.617647059,Y,33,N,N,,Y,259,NORMAL,18,0,No
CDISCPILOT01,1295,01-703-1295,Xanomeline High Dose,81,Xanomeline High Dose,81,11/21/13,4/19/14,88,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,180,5/19/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,21,-3,9,34,2,0.529411765,2.333333333,0.617647059,Y,33,N,N,,Y,259,NORMAL,18,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-8,9/4/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-8,9/4/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,Y,,6,NORMAL,5.13,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-8,9/4/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,Y,,2,NORMAL,61,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-8,9/4/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,,6,32,1.5,0.28125,1.5,0.28125,,39,N,N,Y,,3,NORMAL,9,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-8,9/4/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,,9,34,2.111111111,0.558823529,2.111111111,0.558823529,,32,N,N,Y,,4,NORMAL,19,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,9/28/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,,56,NORMAL,4,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,9/28/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,9/28/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,48,61,-13,35,115,1.371428571,0.417391304,1.742857143,0.530434783,Y,124.5,N,N,,,39,NORMAL,48,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,9/28/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,9,4,6,32,2.166666667,0.40625,1.5,0.28125,,35,N,N,,,40,NORMAL,13,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,17,9/28/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,19,-1,9,34,2,0.529411765,2.111111111,0.558823529,,33,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/10/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.8,4,-0.2,3.4,5.4,1.117647059,0.703703704,1.176470588,0.740740741,Y,4.3,N,N,,,90,NORMAL,3.8,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/10/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,Y,26.37,N,N,,,78,NORMAL,5.13,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/10/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,61,7,35,115,1.942857143,0.591304348,1.742857143,0.530434783,,104.5,N,N,,,74,NORMAL,68,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/10/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,9,-2,6,32,1.166666667,0.21875,1.5,0.28125,Y,41,N,N,,,75,NORMAL,7,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/10/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,19,-2,9,34,1.888888889,0.5,2.111111111,0.558823529,Y,34,N,N,,,76,NORMAL,17,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,10/24/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,,120,NORMAL,4.4,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,10/24/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,10/24/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,61,15,35,115,2.171428571,0.660869565,1.742857143,0.530434783,,96.5,N,N,,,104,NORMAL,76,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,10/24/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,9,4,6,32,2.166666667,0.40625,1.5,0.28125,,35,N,N,,,105,NORMAL,13,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,10/24/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,19,2,9,34,2.333333333,0.617647059,2.111111111,0.558823529,,30,N,N,,,106,NORMAL,21,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,11/7/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,5,4,1,3.4,5.4,1.470588235,0.925925926,1.176470588,0.740740741,,3.3,N,N,,,150,NORMAL,5,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,11/7/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,11/7/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,61,-1,35,115,1.714285714,0.52173913,1.742857143,0.530434783,,112.5,N,N,,,134,NORMAL,60,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,11/7/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,,135,NORMAL,11,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,11/7/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,19,2,9,34,2.333333333,0.617647059,2.111111111,0.558823529,,30,N,N,,,136,NORMAL,21,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/5/12,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.7,4,0.7,3.4,5.4,1.382352941,0.87037037,1.176470588,0.740740741,,3.4,N,N,,,181,NORMAL,4.7,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/5/12,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,168,NORMAL,6.84,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/5/12,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,61,13,35,115,2.114285714,0.643478261,1.742857143,0.530434783,,98.5,N,N,,,164,NORMAL,74,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/5/12,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,,165,NORMAL,11,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/5/12,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,19,3,9,34,2.444444444,0.647058824,2.111111111,0.558823529,,29,N,N,,,166,NORMAL,22,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,1/2/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,3.8,4,-0.2,3.4,5.4,1.117647059,0.703703704,1.176470588,0.740740741,,4.3,N,N,,,215,NORMAL,3.8,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,1/2/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,5.13,5.13,0,3,21,1.71,0.244285714,1.71,0.244285714,,26.37,N,N,,,203,NORMAL,5.13,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,1/2/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,61,-5,35,115,1.6,0.486956522,1.742857143,0.530434783,,116.5,N,N,,,199,NORMAL,56,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,1/2/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,9,1,6,32,1.666666667,0.3125,1.5,0.28125,,38,N,N,,,200,NORMAL,10,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,113,1/2/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,19,1,9,34,2.222222222,0.588235294,2.111111111,0.558823529,,31,N,N,,,201,NORMAL,20,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,1/30/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.2,4,0.2,3.4,5.4,1.235294118,0.777777778,1.176470588,0.740740741,,3.9,N,N,,,245,NORMAL,4.2,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,1/30/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,,233,NORMAL,8.55,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,1/30/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,61,-3,35,115,1.657142857,0.504347826,1.742857143,0.530434783,,114.5,N,N,,,229,NORMAL,58,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,1/30/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,9,3,6,32,2,0.375,1.5,0.28125,,36,N,N,,,230,NORMAL,12,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,141,1/30/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,19,1,9,34,2.222222222,0.588235294,2.111111111,0.558823529,,31,N,N,,,231,NORMAL,20,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,171,3/1/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,5,4,1,3.4,5.4,1.470588235,0.925925926,1.176470588,0.740740741,,3.3,N,N,,Y,276,NORMAL,5,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,171,3/1/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,5,4,1,3.4,5.4,1.470588235,0.925925926,1.176470588,0.740740741,,3.3,N,N,,Y,276,NORMAL,5,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,171,3/1/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,171,3/1/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,5.13,3.42,3,21,2.85,0.407142857,1.71,0.244285714,,22.95,N,N,,Y,263,NORMAL,8.55,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,171,3/1/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,61,-8,35,115,1.514285714,0.460869565,1.742857143,0.530434783,,119.5,N,N,,Y,259,NORMAL,53,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,171,3/1/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,61,-8,35,115,1.514285714,0.460869565,1.742857143,0.530434783,,119.5,N,N,,Y,259,NORMAL,53,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,171,3/1/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,Y,260,NORMAL,11,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,171,3/1/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,Y,260,NORMAL,11,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,171,3/1/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,19,1,9,34,2.222222222,0.588235294,2.111111111,0.558823529,,31,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,171,3/1/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,19,1,9,34,2.222222222,0.588235294,2.111111111,0.558823529,,31,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,183,3/13/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.6,4,0.6,3.4,5.4,1.352941176,0.851851852,1.176470588,0.740740741,,3.5,N,N,,,310,NORMAL,4.6,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,183,3/13/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,6.84,5.13,1.71,3,21,2.28,0.325714286,1.71,0.244285714,,24.66,N,N,,,298,NORMAL,6.84,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,183,3/13/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,61,7,35,115,1.942857143,0.591304348,1.742857143,0.530434783,,104.5,N,N,,,294,NORMAL,68,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,183,3/13/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,9,2,6,32,1.833333333,0.34375,1.5,0.28125,,37,N,N,,,295,NORMAL,11,0,No
CDISCPILOT01,1299,01-703-1299,Placebo,0,Placebo,0,9/12/12,3/13/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,183,3/13/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,19,-1,9,34,2,0.529411765,2.111111111,0.558823529,,33,N,N,,,296,NORMAL,18,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-79,12/28/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,5,NORMAL,6.84,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-79,12/28/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,55,,35,115,1.571428571,0.47826087,1.571428571,0.47826087,,117.5,N,N,Y,,2,NORMAL,55,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-79,12/28/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,22,,6,34,3.666666667,0.647058824,3.666666667,0.647058824,,29,N,N,Y,,3,NORMAL,22,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Baseline,0,-79,12/28/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,26,,9,34,2.888888889,0.764705882,2.888888889,0.764705882,,25,N,N,Y,,4,NORMAL,26,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-24,2/21/14,UNSCHEDULED 1.1,1.1,Potassium (mmol/L),K,19,CHEM,4.9,,,3.4,5.4,1.441176471,0.907407407,,,,3.2,N,,,,39,NORMAL,4.9,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-24,2/21/14,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,26,NORMAL,6.84,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-24,2/21/14,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,55,-4,35,115,1.457142857,0.443478261,1.571428571,0.47826087,,121.5,N,N,,,22,NORMAL,51,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-24,2/21/14,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,22,2,6,34,4,0.705882353,3.666666667,0.647058824,,27,N,N,,,23,NORMAL,24,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, .,,-24,2/21/14,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,26,-2,9,34,2.666666667,0.705882353,2.888888889,0.764705882,,27,N,N,,,24,NORMAL,24,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 2,2,15,3/31/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,,,3.4,5.4,1.264705882,0.796296296,,,,3.8,N,,,,75,NORMAL,4.3,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 2,2,15,3/31/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,63,NORMAL,8.55,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 2,2,15,3/31/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,55,4,35,115,1.685714286,0.513043478,1.571428571,0.47826087,,113.5,N,N,,,59,NORMAL,59,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 2,2,15,3/31/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,22,-7,6,34,2.5,0.441176471,3.666666667,0.647058824,Y,36,N,N,,,60,NORMAL,15,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 2,2,15,3/31/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,26,-3,9,34,2.555555556,0.676470588,2.888888889,0.764705882,,28,N,N,,,61,NORMAL,23,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 4,4,28,4/13/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.8,,,3.4,5.4,1.117647059,0.703703704,,,Y,4.3,N,,,,106,NORMAL,3.8,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 4,4,28,4/13/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,93,NORMAL,8.55,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 4,4,28,4/13/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,55,0,35,115,1.571428571,0.47826087,1.571428571,0.47826087,Y,117.5,N,N,,,89,NORMAL,55,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 4,4,28,4/13/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,22,3,6,34,4.166666667,0.735294118,3.666666667,0.647058824,,26,N,N,,,90,NORMAL,25,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 4,4,28,4/13/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,26,-1,9,34,2.777777778,0.735294118,2.888888889,0.764705882,,26,N,N,,,91,NORMAL,25,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 6,6,69,5/24/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,,,3.4,5.4,1.235294118,0.777777778,,,,3.9,N,,,Y,141,NORMAL,4.2,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y,End of Treatment,99,69,5/24/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.2,,,3.4,5.4,1.235294118,0.777777778,,,,3.9,N,,,Y,141,NORMAL,4.2,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 6,6,69,5/24/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,128,NORMAL,6.84,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y,End of Treatment,99,69,5/24/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,Y,128,NORMAL,6.84,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 6,6,69,5/24/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,55,2,35,115,1.628571429,0.495652174,1.571428571,0.47826087,,115.5,N,N,,Y,124,NORMAL,57,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y,End of Treatment,99,69,5/24/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,55,2,35,115,1.628571429,0.495652174,1.571428571,0.47826087,,115.5,N,N,,Y,124,NORMAL,57,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 6,6,69,5/24/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,22,-5,6,34,2.833333333,0.5,3.666666667,0.647058824,,34,N,N,,Y,125,NORMAL,17,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y,End of Treatment,99,69,5/24/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,22,-5,6,34,2.833333333,0.5,3.666666667,0.647058824,,34,N,N,,Y,125,NORMAL,17,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y, Week 6,6,69,5/24/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,26,-12,9,34,1.555555556,0.411764706,2.888888889,0.764705882,Y,37,N,N,,Y,126,NORMAL,14,0,No
CDISCPILOT01,1335,01-703-1335,Xanomeline High Dose,81,Xanomeline High Dose,81,3/17/14,5/7/14,67,65-80,2,BLACK OR AFRICAN AMERICAN,2,F,N,,Y,End of Treatment,99,69,5/24/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,26,-12,9,34,1.555555556,0.411764706,2.888888889,0.764705882,Y,37,N,N,,Y,126,NORMAL,14,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,9/12/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,19,NORMAL,4.6,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,9/12/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,9/12/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,98,,35,115,2.8,0.852173913,2.8,0.852173913,,80.5,N,N,Y,,2,NORMAL,98,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,9/12/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,,6,32,1.5,0.28125,1.5,0.28125,,39,N,N,Y,,3,NORMAL,9,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Baseline,0,-10,9/12/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,16,10/7/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.6,0,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,,,55,NORMAL,4.6,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,16,10/7/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,Y,26.37,N,N,,,43,NORMAL,5.13,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,16,10/7/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,98,-6,35,115,2.628571429,0.8,2.8,0.852173913,,80.5,N,N,,,39,NORMAL,92,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,16,10/7/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,5,9,-4,6,32,0.833333333,0.15625,1.5,0.28125,Y,43,N,N,,,40,LOW,5,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 2,2,16,10/7/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,9,34,2,0.529411765,2.222222222,0.588235294,Y,33,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,28,10/19/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,85,NORMAL,4.4,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,28,10/19/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,73,NORMAL,6.84,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,28,10/19/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,98,-3,35,115,2.714285714,0.826086957,2.8,0.852173913,,77.5,N,N,,,69,NORMAL,95,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,28,10/19/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,9,-2,6,32,1.166666667,0.21875,1.5,0.28125,,41,N,N,,,70,NORMAL,7,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 4,4,28,10/19/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,0,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,,,71,NORMAL,20,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,48,11/8/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,115,NORMAL,4.4,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,48,11/8/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,103,NORMAL,6.84,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,48,11/8/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,98,-3,35,115,2.714285714,0.826086957,2.8,0.852173913,,77.5,N,N,,,99,NORMAL,95,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,48,11/8/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,6,9,-3,6,32,1,0.1875,1.5,0.28125,,42,N,N,,,100,NORMAL,6,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 6,6,48,11/8/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,,28,N,N,,,101,NORMAL,23,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,11/17/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,5.3,4.6,0.7,3.4,5.4,1.558823529,0.981481481,1.352941176,0.851851852,,3.6,N,N,,,145,NORMAL,5.3,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,11/17/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,133,NORMAL,8.55,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,11/17/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,98,-9,35,115,2.542857143,0.773913043,2.8,0.852173913,,83.5,N,N,,,129,NORMAL,89,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,11/17/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,6,9,-3,6,32,1,0.1875,1.5,0.28125,,42,N,N,,,130,NORMAL,6,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 8,8,57,11/17/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,,28,N,N,,,131,NORMAL,23,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,12/15/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,Y,3.9,N,N,,,176,NORMAL,4.2,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,12/15/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,163,NORMAL,6.84,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,12/15/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,106,98,8,35,115,3.028571429,0.92173913,2.8,0.852173913,Y,88.5,N,N,,,159,NORMAL,106,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,12/15/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,9,1,6,32,1.666666667,0.3125,1.5,0.28125,,38,N,N,,,160,NORMAL,10,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 12,12,85,12/15/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,9,34,2.555555556,0.676470588,2.222222222,0.588235294,,28,N,N,,,161,NORMAL,23,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,1/11/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,5,4.6,0.4,3.4,5.4,1.470588235,0.925925926,1.352941176,0.851851852,,3.3,N,N,,,210,NORMAL,5,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,1/11/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,5.13,6.84,-1.71,3,21,1.71,0.244285714,2.28,0.325714286,,26.37,N,N,,,198,NORMAL,5.13,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,1/11/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,96,98,-2,35,115,2.742857143,0.834782609,2.8,0.852173913,,78.5,N,N,,,194,NORMAL,96,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,1/11/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,6,9,-3,6,32,1,0.1875,1.5,0.28125,,42,N,N,,,195,NORMAL,6,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 16,16,112,1/11/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,20,1,9,34,2.333333333,0.617647059,2.222222222,0.588235294,,30,N,N,,,196,NORMAL,21,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,2/9/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.8,4.6,0.2,3.4,5.4,1.411764706,0.888888889,1.352941176,0.851851852,,3.3,N,N,,,240,NORMAL,4.8,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,2/9/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,,,228,NORMAL,6.84,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,2/9/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,98,-5,35,115,2.657142857,0.808695652,2.8,0.852173913,,79.5,N,N,,,224,NORMAL,93,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,2/9/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,9,15,6,32,4,0.75,1.5,0.28125,,24,N,N,,,225,NORMAL,24,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 20,20,141,2/9/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,33,20,13,9,34,3.666666667,0.970588235,2.222222222,0.588235294,,28.5,N,N,,,226,NORMAL,33,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,3/8/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,Y,271,NORMAL,4.4,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,3/8/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,Y,271,NORMAL,4.4,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,3/8/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,258,NORMAL,8.55,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,3/8/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,258,NORMAL,8.55,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,3/8/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,98,-7,35,115,2.6,0.791304348,2.8,0.852173913,,81.5,N,N,,Y,254,NORMAL,91,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,3/8/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,98,-7,35,115,2.6,0.791304348,2.8,0.852173913,,81.5,N,N,,Y,254,NORMAL,91,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,3/8/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,9,11,6,32,3.333333333,0.625,1.5,0.28125,,28,N,N,,Y,255,NORMAL,20,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,3/8/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,9,11,6,32,3.333333333,0.625,1.5,0.28125,,28,N,N,,Y,255,NORMAL,20,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 24,24,168,3/8/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,37,20,17,9,34,4.111111111,1.088235294,2.222222222,0.588235294,,32.5,N,N,,Y,256,HIGH,37,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y,End of Treatment,99,168,3/8/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,37,20,17,9,34,4.111111111,1.088235294,2.222222222,0.588235294,,32.5,N,N,,Y,256,HIGH,37,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,181,3/21/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,,306,NORMAL,4.2,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,181,3/21/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,294,NORMAL,8.55,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,181,3/21/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,85,98,-13,35,115,2.428571429,0.739130435,2.8,0.852173913,,87.5,N,N,,,289,NORMAL,85,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,181,3/21/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,9,11,6,32,3.333333333,0.625,1.5,0.28125,,28,N,N,,,290,NORMAL,20,0,No
CDISCPILOT01,1379,01-703-1379,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/22/13,3/21/14,81,>80,3,BLACK OR AFRICAN AMERICAN,2,F,Y,,Y, Week 26,26,181,3/21/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,20,12,9,34,3.555555556,0.941176471,2.222222222,0.588235294,,27.5,N,N,,,292,NORMAL,32,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,11/28/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,5.1,5.1,,3.4,5.4,1.5,0.944444444,1.5,0.944444444,,3.4,N,N,Y,,19,NORMAL,5.1,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,11/28/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,11/28/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,73,,35,115,2.085714286,0.634782609,2.085714286,0.634782609,,99.5,N,N,Y,,2,NORMAL,73,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,11/28/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,40,40,,6,43,6.666666667,0.930232558,6.666666667,0.930232558,,37,N,N,Y,,3,NORMAL,40,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-14,11/28/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,28,,11,36,2.545454545,0.777777778,2.545454545,0.777777778,,26,N,N,Y,,4,NORMAL,28,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,8,12/19/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.9,5.1,-1.2,3.4,5.4,1.147058824,0.722222222,1.5,0.944444444,Y,4.2,N,N,,Y,55,NORMAL,3.9,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,8,12/19/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.9,5.1,-1.2,3.4,5.4,1.147058824,0.722222222,1.5,0.944444444,Y,4.2,N,N,,Y,55,NORMAL,3.9,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,8,12/19/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,Y,19.53,N,N,,Y,43,NORMAL,11.97,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,8,12/19/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,Y,19.53,N,N,,Y,43,NORMAL,11.97,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,8,12/19/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,73,-8,35,115,1.857142857,0.565217391,2.085714286,0.634782609,Y,107.5,N,N,,Y,39,NORMAL,65,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,8,12/19/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,73,-8,35,115,1.857142857,0.565217391,2.085714286,0.634782609,Y,107.5,N,N,,Y,39,NORMAL,65,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,8,12/19/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,40,-21,6,43,3.166666667,0.441860465,6.666666667,0.930232558,Y,45.5,N,N,,Y,40,NORMAL,19,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,8,12/19/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,40,-21,6,43,3.166666667,0.441860465,6.666666667,0.930232558,Y,45.5,N,N,,Y,40,NORMAL,19,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,8,12/19/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,28,-4,11,36,2.181818182,0.666666667,2.545454545,0.777777778,Y,30,N,N,,Y,41,NORMAL,24,0,No
CDISCPILOT01,1403,01-703-1403,Xanomeline High Dose,81,Xanomeline High Dose,81,12/12/12,12/13/12,67,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,8,12/19/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,28,-4,11,36,2.181818182,0.666666667,2.545454545,0.777777778,Y,30,N,N,,Y,41,NORMAL,24,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,96,96,,35,115,2.742857143,0.834782609,2.742857143,0.834782609,,78.5,N,N,Y,,2,NORMAL,96,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,,6,32,3.833333333,0.71875,3.833333333,0.71875,,25,N,N,Y,,3,NORMAL,23,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-13,2/27/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,29,,9,34,3.222222222,0.852941176,3.222222222,0.852941176,,24.5,N,N,Y,,4,NORMAL,29,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,5.4,4.5,0.9,3.4,5.4,1.588235294,1,1.323529412,0.833333333,,3.7,N,N,,,56,NORMAL,5.4,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,99,96,3,35,115,2.828571429,0.860869565,2.742857143,0.834782609,,81.5,N,N,,,39,NORMAL,99,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,23,1,6,32,4,0.75,3.833333333,0.71875,,24,N,N,,,40,NORMAL,24,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,3/26/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,29,-6,9,34,2.555555556,0.676470588,3.222222222,0.852941176,,28,N,N,,,41,NORMAL,23,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/8/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,5.2,4.5,0.7,3.4,5.4,1.529411765,0.962962963,1.323529412,0.833333333,,3.5,N,N,,,90,NORMAL,5.2,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/8/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,10.26,3.42,3,21,4.56,0.651428571,3.42,0.488571429,,17.82,N,N,,,78,NORMAL,13.68,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/8/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,96,-3,35,115,2.657142857,0.808695652,2.742857143,0.834782609,,79.5,N,N,,,74,NORMAL,93,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/8/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,23,1,6,32,4,0.75,3.833333333,0.71875,,24,N,N,,,75,NORMAL,24,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,28,4/8/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,29,-1,9,34,3.111111111,0.823529412,3.222222222,0.852941176,,23.5,N,N,,,76,NORMAL,28,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,41,4/21/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.9,4.5,0.4,3.4,5.4,1.441176471,0.907407407,1.323529412,0.833333333,,3.2,N,N,,,120,NORMAL,4.9,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,41,4/21/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,15.39,10.26,5.13,3,21,5.13,0.732857143,3.42,0.488571429,,16.11,N,N,,,108,NORMAL,15.39,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,41,4/21/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,96,-12,35,115,2.4,0.730434783,2.742857143,0.834782609,Y,88.5,N,N,,,104,NORMAL,84,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,41,4/21/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,23,4,6,32,4.5,0.84375,3.833333333,0.71875,,24,N,N,,,105,NORMAL,27,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,41,4/21/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,29,-2,9,34,3,0.794117647,3.222222222,0.852941176,,24,N,N,,,106,NORMAL,27,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,55,5/5/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,5.2,4.5,0.7,3.4,5.4,1.529411765,0.962962963,1.323529412,0.833333333,,3.5,N,N,,,150,NORMAL,5.2,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,55,5/5/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,Y,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,55,5/5/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,96,-1,35,115,2.714285714,0.826086957,2.742857143,0.834782609,,77.5,N,N,,,134,NORMAL,95,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,55,5/5/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,23,-5,6,32,3,0.5625,3.833333333,0.71875,Y,30,N,N,,,135,NORMAL,18,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,55,5/5/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,29,-8,9,34,2.333333333,0.617647059,3.222222222,0.852941176,Y,30,N,N,,,136,NORMAL,21,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,83,6/2/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,Y,4,N,N,,,181,NORMAL,4.1,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,83,6/2/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,168,NORMAL,11.97,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,83,6/2/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,96,-6,35,115,2.571428571,0.782608696,2.742857143,0.834782609,,82.5,N,N,,,164,NORMAL,90,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,83,6/2/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,27,23,4,6,32,4.5,0.84375,3.833333333,0.71875,,24,N,N,,,165,NORMAL,27,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,83,6/2/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,29,0,9,34,3.222222222,0.852941176,3.222222222,0.852941176,,24.5,N,N,,,166,NORMAL,29,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,111,6/30/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.6,4.5,0.1,3.4,5.4,1.352941176,0.851851852,1.323529412,0.833333333,,3.5,N,N,,,215,NORMAL,4.6,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,111,6/30/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,203,NORMAL,11.97,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,111,6/30/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,96,-8,35,115,2.514285714,0.765217391,2.742857143,0.834782609,,84.5,N,N,,,199,NORMAL,88,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,111,6/30/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,23,0,6,32,3.833333333,0.71875,3.833333333,0.71875,,25,N,N,,,200,NORMAL,23,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,111,6/30/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,29,-3,9,34,2.888888889,0.764705882,3.222222222,0.852941176,,25,N,N,,,201,NORMAL,26,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,140,7/29/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,5.3,4.5,0.8,3.4,5.4,1.558823529,0.981481481,1.323529412,0.833333333,,3.6,N,N,,,246,NORMAL,5.3,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,140,7/29/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,234,NORMAL,10.26,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,140,7/29/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,96,-12,35,115,2.4,0.730434783,2.742857143,0.834782609,,88.5,N,N,,,229,NORMAL,84,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,140,7/29/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,23,1,6,32,4,0.75,3.833333333,0.71875,,24,N,N,,,230,NORMAL,24,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,140,7/29/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,29,-1,9,34,3.111111111,0.823529412,3.222222222,0.852941176,,23.5,N,N,,,232,NORMAL,28,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,8/28/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,5,4.5,0.5,3.4,5.4,1.470588235,0.925925926,1.323529412,0.833333333,,3.3,N,N,,Y,279,NORMAL,5,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,8/28/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,5,4.5,0.5,3.4,5.4,1.470588235,0.925925926,1.323529412,0.833333333,,3.3,N,N,,Y,279,NORMAL,5,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,8/28/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,Y,266,NORMAL,11.97,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,8/28/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,Y,266,NORMAL,11.97,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,8/28/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,96,-8,35,115,2.514285714,0.765217391,2.742857143,0.834782609,,84.5,N,N,,Y,261,NORMAL,88,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,8/28/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,96,-8,35,115,2.514285714,0.765217391,2.742857143,0.834782609,,84.5,N,N,,Y,261,NORMAL,88,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,8/28/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,23,1,6,32,4,0.75,3.833333333,0.71875,,24,N,N,,Y,262,NORMAL,24,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,8/28/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,23,1,6,32,4,0.75,3.833333333,0.71875,,24,N,N,,Y,262,NORMAL,24,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,170,8/28/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,29,2,9,34,3.444444444,0.911764706,3.222222222,0.852941176,,26.5,N,N,,Y,264,NORMAL,31,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,170,8/28/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,29,2,9,34,3.444444444,0.911764706,3.222222222,0.852941176,,26.5,N,N,,Y,264,NORMAL,31,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,9/11/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.2,4.5,-0.3,3.4,5.4,1.235294118,0.777777778,1.323529412,0.833333333,,3.9,N,N,,,314,NORMAL,4.2,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,9/11/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,302,NORMAL,11.97,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,9/11/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,96,-16,35,115,2.285714286,0.695652174,2.742857143,0.834782609,,92.5,N,N,,,298,NORMAL,80,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,9/11/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,23,-2,6,32,3.5,0.65625,3.833333333,0.71875,,27,N,N,,,299,NORMAL,21,0,No
CDISCPILOT01,1439,01-703-1439,Xanomeline High Dose,81,Xanomeline High Dose,81,3/12/14,9/11/14,76,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,184,9/11/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,29,-9,9,34,2.222222222,0.588235294,3.222222222,0.852941176,,31,N,N,,,300,NORMAL,20,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-49,11/25/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,3.9,3.9,,3.4,5.4,1.147058824,0.722222222,1.147058824,0.722222222,,4.2,N,N,Y,,19,NORMAL,3.9,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-49,11/25/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,22.23,22.23,,3,21,7.41,1.058571429,7.41,1.058571429,,20.73,N,N,Y,,6,HIGH,22.23,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-49,11/25/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,53,,35,115,1.514285714,0.460869565,1.514285714,0.460869565,,119.5,N,N,Y,,2,NORMAL,53,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-49,11/25/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,32,2.666666667,0.5,2.666666667,0.5,,32,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-49,11/25/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,,9,34,2.111111111,0.558823529,2.111111111,0.558823529,,32,N,N,Y,,4,NORMAL,19,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, .,,-7,1/6/13,UNSCHEDULED 1.1,1.1,Potassium (mmol/L),K,19,CHEM,4.2,3.9,0.3,3.4,5.4,1.235294118,0.777777778,1.147058824,0.722222222,,3.9,N,N,,,56,NORMAL,4.2,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, .,,-7,1/6/13,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,15.39,22.23,-6.84,3,21,5.13,0.732857143,7.41,1.058571429,,16.11,N,N,,,43,NORMAL,15.39,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, .,,-7,1/6/13,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,53,5,35,115,1.657142857,0.504347826,1.514285714,0.460869565,,114.5,N,N,,,39,NORMAL,58,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, .,,-7,1/6/13,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,0,6,32,2.666666667,0.5,2.666666667,0.5,,32,N,N,,,40,NORMAL,16,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, .,,-7,1/6/13,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,19,-2,9,34,1.888888889,0.5,2.111111111,0.558823529,,34,N,N,,,41,NORMAL,17,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,16,1/28/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.1,3.9,0.2,3.4,5.4,1.205882353,0.759259259,1.147058824,0.722222222,Y,4,N,N,,,93,NORMAL,4.1,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,16,1/28/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,15.39,22.23,-6.84,3,21,5.13,0.732857143,7.41,1.058571429,,16.11,N,N,,,80,NORMAL,15.39,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,16,1/28/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,53,0,35,115,1.514285714,0.460869565,1.514285714,0.460869565,Y,119.5,N,N,,,76,NORMAL,53,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,16,1/28/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,32,2.5,0.46875,2.666666667,0.5,,33,N,N,,,77,NORMAL,15,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,16,1/28/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,0,9,34,2.111111111,0.558823529,2.111111111,0.558823529,,32,N,N,,,78,NORMAL,19,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,2/9/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.9,3.9,1,3.4,5.4,1.441176471,0.907407407,1.147058824,0.722222222,,3.2,N,N,,,127,NORMAL,4.9,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,2/9/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,22.23,-8.55,3,21,4.56,0.651428571,7.41,1.058571429,Y,17.82,N,N,,,115,NORMAL,13.68,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,2/9/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,53,0,35,115,1.514285714,0.460869565,1.514285714,0.460869565,,119.5,N,N,,,111,NORMAL,53,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,2/9/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,16,-3,6,32,2.166666667,0.40625,2.666666667,0.5,Y,35,N,N,,,112,NORMAL,13,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,2/9/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,19,-1,9,34,2,0.529411765,2.111111111,0.558823529,Y,33,N,N,,,113,NORMAL,18,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,44,2/25/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,3.9,0.5,3.4,5.4,1.294117647,0.814814815,1.147058824,0.722222222,,3.7,N,N,,Y,155,NORMAL,4.4,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,44,2/25/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,3.9,0.5,3.4,5.4,1.294117647,0.814814815,1.147058824,0.722222222,,3.7,N,N,,Y,155,NORMAL,4.4,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,44,2/25/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,18.81,22.23,-3.42,3,21,6.27,0.895714286,7.41,1.058571429,,17.31,N,N,,Y,144,NORMAL,18.81,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,44,2/25/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,18.81,22.23,-3.42,3,21,6.27,0.895714286,7.41,1.058571429,,17.31,N,N,,Y,144,NORMAL,18.81,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,44,2/25/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,53,4,35,115,1.628571429,0.495652174,1.514285714,0.460869565,,115.5,N,N,,Y,141,NORMAL,57,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,44,2/25/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,53,4,35,115,1.628571429,0.495652174,1.514285714,0.460869565,,115.5,N,N,,Y,141,NORMAL,57,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,44,2/25/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,16,9,6,32,4.166666667,0.78125,2.666666667,0.5,,23,N,N,,Y,142,NORMAL,25,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,44,2/25/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,16,9,6,32,4.166666667,0.78125,2.666666667,0.5,,23,N,N,,Y,142,NORMAL,25,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,44,2/25/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,19,10,9,34,3.222222222,0.852941176,2.111111111,0.558823529,,24.5,N,N,,Y,143,NORMAL,29,0,No
CDISCPILOT01,1008,01-704-1008,Xanomeline High Dose,81,Xanomeline High Dose,81,1/13/13,2/21/13,76,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,44,2/25/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,19,10,9,34,3.222222222,0.852941176,2.111111111,0.558823529,,24.5,N,N,,Y,143,NORMAL,29,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Baseline,0,-7,8/20/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,18,NORMAL,4.3,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Baseline,0,-7,8/20/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Baseline,0,-7,8/20/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,65,,35,115,1.857142857,0.565217391,1.857142857,0.565217391,,107.5,N,N,Y,,2,NORMAL,65,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Baseline,0,-7,8/20/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,24,,6,35,4,0.685714286,4,0.685714286,,28.5,N,N,Y,,3,NORMAL,24,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Baseline,0,-7,8/20/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,27,,11,36,2.454545455,0.75,2.454545455,0.75,,27,N,N,Y,,4,NORMAL,27,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Week 2,2,19,9/14/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,4.3,-0.3,3.4,5.4,1.176470588,0.740740741,1.264705882,0.796296296,Y,4.1,N,N,,Y,53,NORMAL,4,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,19,9/14/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,4.3,-0.3,3.4,5.4,1.176470588,0.740740741,1.264705882,0.796296296,Y,4.1,N,N,,Y,53,NORMAL,4,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Week 2,2,19,9/14/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,Y,19.53,N,N,,Y,40,NORMAL,11.97,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,19,9/14/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,Y,19.53,N,N,,Y,40,NORMAL,11.97,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Week 2,2,19,9/14/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,65,-1,35,115,1.828571429,0.556521739,1.857142857,0.565217391,Y,108.5,N,N,,Y,36,NORMAL,64,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,19,9/14/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,65,-1,35,115,1.828571429,0.556521739,1.857142857,0.565217391,Y,108.5,N,N,,Y,36,NORMAL,64,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Week 2,2,19,9/14/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,39,24,15,6,35,6.5,1.114285714,4,0.685714286,Y,36,N,N,,Y,37,HIGH,39,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,19,9/14/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,39,24,15,6,35,6.5,1.114285714,4,0.685714286,Y,36,N,N,,Y,37,HIGH,39,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y, Week 2,2,19,9/14/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,27,8,11,36,3.181818182,0.972222222,2.454545455,0.75,Y,29.5,N,N,,Y,38,NORMAL,35,0,No
CDISCPILOT01,1009,01-704-1009,Xanomeline Low Dose,54,Xanomeline Low Dose,54,8/27/13,9/25/13,83,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,19,9/14/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,27,8,11,36,3.181818182,0.972222222,2.454545455,0.75,Y,29.5,N,N,,Y,38,NORMAL,35,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-14,2/7/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-14,2/7/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,18.81,18.81,,3,21,6.27,0.895714286,6.27,0.895714286,,17.31,N,N,Y,,6,NORMAL,18.81,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-14,2/7/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,Y,,2,NORMAL,61,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-14,2/7/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,,6,35,1.5,0.257142857,1.5,0.257142857,,43.5,N,N,Y,,3,NORMAL,9,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-14,2/7/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,16,,11,36,1.454545455,0.444444444,1.454545455,0.444444444,,38,N,N,Y,,4,NORMAL,16,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 2,2,16,3/8/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,4.5,-0.5,3.4,5.4,1.176470588,0.740740741,1.323529412,0.833333333,,4.1,N,N,,,56,NORMAL,4,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 2,2,16,3/8/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,18.81,18.81,0,3,21,6.27,0.895714286,6.27,0.895714286,,17.31,N,N,,,43,NORMAL,18.81,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 2,2,16,3/8/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,61,3,35,115,1.828571429,0.556521739,1.742857143,0.530434783,,108.5,N,N,,,39,NORMAL,64,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 2,2,16,3/8/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,6,9,-3,6,35,1,0.171428571,1.5,0.257142857,Y,46.5,N,N,,,40,NORMAL,6,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 2,2,16,3/8/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,16,-3,11,36,1.181818182,0.361111111,1.454545455,0.444444444,Y,41,N,N,,,41,NORMAL,13,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 4,4,31,3/23/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,90,NORMAL,4.1,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 4,4,31,3/23/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,20.52,18.81,1.71,3,21,6.84,0.977142857,6.27,0.895714286,,19.02,N,N,,,78,NORMAL,20.52,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 4,4,31,3/23/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,61,5,35,115,1.885714286,0.573913043,1.742857143,0.530434783,,106.5,N,N,,,74,NORMAL,66,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 4,4,31,3/23/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,9,5,6,35,2.333333333,0.4,1.5,0.257142857,,38.5,N,N,,,75,NORMAL,14,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 4,4,31,3/23/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,16,-2,11,36,1.272727273,0.388888889,1.454545455,0.444444444,,40,N,N,,,76,NORMAL,14,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 6,6,50,4/11/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,,120,NORMAL,4.3,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 6,6,50,4/11/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,22.23,18.81,3.42,3,21,7.41,1.058571429,6.27,0.895714286,Y,20.73,N,N,,,108,HIGH,22.23,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 6,6,50,4/11/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,61,3,35,115,1.828571429,0.556521739,1.742857143,0.530434783,,108.5,N,N,,,104,NORMAL,64,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 6,6,50,4/11/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,9,-2,6,35,1.166666667,0.2,1.5,0.257142857,,45.5,N,N,,,105,NORMAL,7,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 6,6,50,4/11/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,16,-1,11,36,1.363636364,0.416666667,1.454545455,0.444444444,,39,N,N,,,106,NORMAL,15,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 8,8,63,4/24/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,,150,NORMAL,4.3,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 8,8,63,4/24/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,15.39,18.81,-3.42,3,21,5.13,0.732857143,6.27,0.895714286,,16.11,N,N,,,138,NORMAL,15.39,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 8,8,63,4/24/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,61,-5,35,115,1.6,0.486956522,1.742857143,0.530434783,,116.5,N,N,,,134,NORMAL,56,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 8,8,63,4/24/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,9,-2,6,35,1.166666667,0.2,1.5,0.257142857,,45.5,N,N,,,135,NORMAL,7,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 8,8,63,4/24/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,16,-2,11,36,1.272727273,0.388888889,1.454545455,0.444444444,,40,N,N,,,136,NORMAL,14,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, .,,99,5/30/14,UNSCHEDULED 9.2,9.2,Potassium (mmol/L),K,19,CHEM,4.2,4.5,-0.3,3.4,5.4,1.235294118,0.777777778,1.323529412,0.833333333,,3.9,N,N,,,181,NORMAL,4.2,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, .,,99,5/30/14,UNSCHEDULED 9.2,9.2,Bilirubin (umol/L),BILI,21,CHEM,22.23,18.81,3.42,3,21,7.41,1.058571429,6.27,0.895714286,,20.73,N,N,,,168,HIGH,22.23,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, .,,99,5/30/14,UNSCHEDULED 9.2,9.2,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,61,4,35,115,1.857142857,0.565217391,1.742857143,0.530434783,,107.5,N,N,,,164,NORMAL,65,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, .,,99,5/30/14,UNSCHEDULED 9.2,9.2,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,9,0,6,35,1.5,0.257142857,1.5,0.257142857,,43.5,N,N,,,165,NORMAL,9,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, .,,99,5/30/14,UNSCHEDULED 9.2,9.2,Aspartate Aminotransferase (U/L),AST,25,CHEM,12,16,-4,11,36,1.090909091,0.333333333,1.454545455,0.444444444,,42,N,N,,,166,NORMAL,12,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 16,16,113,6/13/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,4.5,-0.1,3.4,5.4,1.294117647,0.814814815,1.323529412,0.833333333,,3.7,N,N,,,215,NORMAL,4.4,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 16,16,113,6/13/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,18.81,18.81,0,3,21,6.27,0.895714286,6.27,0.895714286,,17.31,N,N,,,203,NORMAL,18.81,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 16,16,113,6/13/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,62,61,1,35,115,1.771428571,0.539130435,1.742857143,0.530434783,,110.5,N,N,,,199,NORMAL,62,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 16,16,113,6/13/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,8,9,-1,6,35,1.333333333,0.228571429,1.5,0.257142857,,44.5,N,N,,,200,NORMAL,8,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 16,16,113,6/13/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,16,-1,11,36,1.363636364,0.416666667,1.454545455,0.444444444,,39,N,N,,,201,NORMAL,15,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 20,20,139,7/9/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.9,4.5,-0.6,3.4,5.4,1.147058824,0.722222222,1.323529412,0.833333333,Y,4.2,N,N,,Y,246,NORMAL,3.9,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,139,7/9/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.9,4.5,-0.6,3.4,5.4,1.147058824,0.722222222,1.323529412,0.833333333,Y,4.2,N,N,,Y,246,NORMAL,3.9,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 20,20,139,7/9/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,22.23,18.81,3.42,3,21,7.41,1.058571429,6.27,0.895714286,,20.73,N,N,,Y,233,HIGH,22.23,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,139,7/9/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,22.23,18.81,3.42,3,21,7.41,1.058571429,6.27,0.895714286,,20.73,N,N,,Y,233,HIGH,22.23,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 20,20,139,7/9/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,61,-9,35,115,1.485714286,0.452173913,1.742857143,0.530434783,Y,120.5,N,N,,Y,229,NORMAL,52,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,139,7/9/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,61,-9,35,115,1.485714286,0.452173913,1.742857143,0.530434783,Y,120.5,N,N,,Y,229,NORMAL,52,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 20,20,139,7/9/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,9,3,6,35,2,0.342857143,1.5,0.257142857,,40.5,N,N,,Y,230,NORMAL,12,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,139,7/9/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,9,3,6,35,2,0.342857143,1.5,0.257142857,,40.5,N,N,,Y,230,NORMAL,12,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y, Week 20,20,139,7/9/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,16,5,11,36,1.909090909,0.583333333,1.454545455,0.444444444,,33,N,N,,Y,231,NORMAL,21,0,No
CDISCPILOT01,1010,01-704-1010,Placebo,0,Placebo,0,2/21/14,7/8/14,80,65-80,2,WHITE,1,M,N,,Y,End of Treatment,99,139,7/9/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,16,5,11,36,1.909090909,0.583333333,1.454545455,0.444444444,,33,N,N,,Y,231,NORMAL,21,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-16,9/20/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-16,9/20/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-16,9/20/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,98,98,,35,115,2.8,0.852173913,2.8,0.852173913,,80.5,N,N,Y,,2,NORMAL,98,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-16,9/20/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,10,,6,35,1.666666667,0.285714286,1.666666667,0.285714286,,42.5,N,N,Y,,3,NORMAL,10,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-16,9/20/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,13,,11,36,1.181818182,0.361111111,1.181818182,0.361111111,,41,N,N,Y,,4,NORMAL,13,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,14,10/19/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,Y,4.2,N,N,,,56,NORMAL,3.9,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,14,10/19/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,Y,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,14,10/19/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,98,-5,35,115,2.657142857,0.808695652,2.8,0.852173913,,79.5,N,N,,,39,NORMAL,93,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,14,10/19/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,10,1,6,35,1.833333333,0.314285714,1.666666667,0.285714286,,41.5,N,N,,,40,NORMAL,11,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,14,10/19/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,13,4,11,36,1.545454545,0.472222222,1.181818182,0.361111111,,37,N,N,,,41,NORMAL,17,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/1/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,Y,90,NORMAL,4.1,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,27,11/1/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,Y,90,NORMAL,4.1,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/1/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,11.97,1.71,3,21,4.56,0.651428571,3.99,0.57,,17.82,N,N,,Y,78,NORMAL,13.68,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,27,11/1/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,11.97,1.71,3,21,4.56,0.651428571,3.99,0.57,,17.82,N,N,,Y,78,NORMAL,13.68,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/1/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,98,-12,35,115,2.457142857,0.747826087,2.8,0.852173913,Y,86.5,N,N,,Y,74,NORMAL,86,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,27,11/1/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,98,-12,35,115,2.457142857,0.747826087,2.8,0.852173913,Y,86.5,N,N,,Y,74,NORMAL,86,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/1/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,10,0,6,35,1.666666667,0.285714286,1.666666667,0.285714286,Y,42.5,N,N,,Y,75,NORMAL,10,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,27,11/1/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,10,0,6,35,1.666666667,0.285714286,1.666666667,0.285714286,Y,42.5,N,N,,Y,75,NORMAL,10,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,11/1/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,12,13,-1,11,36,1.090909091,0.333333333,1.181818182,0.361111111,Y,42,N,N,,Y,76,NORMAL,12,0,No
CDISCPILOT01,1017,01-704-1017,Xanomeline High Dose,81,Xanomeline High Dose,81,10/6/13,11/18/13,77,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,27,11/1/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,12,13,-1,11,36,1.090909091,0.333333333,1.181818182,0.361111111,Y,42,N,N,,Y,76,NORMAL,12,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-14,9/13/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.2,4.2,,3.4,5.4,1.235294118,0.777777778,1.235294118,0.777777778,,3.9,N,N,Y,,19,NORMAL,4.2,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-14,9/13/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-14,9/13/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,118,118,,35,115,3.371428571,1.026086957,3.371428571,1.026086957,,100.5,N,N,Y,,2,HIGH,118,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-14,9/13/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,32,3.166666667,0.59375,3.166666667,0.59375,,29,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Baseline,0,-14,9/13/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,30,30,,9,34,3.333333333,0.882352941,3.333333333,0.882352941,,25.5,N,N,Y,,4,NORMAL,30,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,15,10/11/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.9,4.2,0.7,3.4,5.4,1.441176471,0.907407407,1.235294118,0.777777778,,3.2,N,N,,,56,NORMAL,4.9,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,15,10/11/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,Y,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,15,10/11/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,140,118,22,35,115,4,1.217391304,3.371428571,1.026086957,Y,122.5,N,N,,,39,HIGH,140,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,15,10/11/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,19,4,6,32,3.833333333,0.71875,3.166666667,0.59375,,25,N,N,,,40,NORMAL,23,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 2,2,15,10/11/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,34,30,4,9,34,3.777777778,1,3.333333333,0.882352941,,29.5,N,N,,,41,NORMAL,34,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,29,10/25/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.5,4.2,0.3,3.4,5.4,1.323529412,0.833333333,1.235294118,0.777777778,Y,3.6,N,N,,Y,90,NORMAL,4.5,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,29,10/25/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.5,4.2,0.3,3.4,5.4,1.323529412,0.833333333,1.235294118,0.777777778,Y,3.6,N,N,,Y,90,NORMAL,4.5,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,29,10/25/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,78,NORMAL,10.26,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,29,10/25/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,78,NORMAL,10.26,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,29,10/25/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,118,-13,35,115,3,0.913043478,3.371428571,1.026086957,,87.5,N,N,,Y,74,NORMAL,105,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,29,10/25/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,118,-13,35,115,3,0.913043478,3.371428571,1.026086957,,87.5,N,N,,Y,74,NORMAL,105,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,29,10/25/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,19,3,6,32,3.666666667,0.6875,3.166666667,0.59375,Y,26,N,N,,Y,75,NORMAL,22,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,29,10/25/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,19,3,6,32,3.666666667,0.6875,3.166666667,0.59375,Y,26,N,N,,Y,75,NORMAL,22,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y, Week 4,4,29,10/25/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,30,5,9,34,3.888888889,1.029411765,3.333333333,0.882352941,Y,30.5,N,N,,Y,76,HIGH,35,0,No
CDISCPILOT01,1025,01-704-1025,Xanomeline Low Dose,54,Xanomeline Low Dose,54,9/27/13,10/24/13,81,>80,3,WHITE,1,F,N,Y,Y,End of Treatment,99,29,10/25/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,30,5,9,34,3.888888889,1.029411765,3.333333333,0.882352941,Y,30.5,N,N,,Y,76,HIGH,35,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,10/17/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,10/17/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,10/17/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,60,,35,115,1.714285714,0.52173913,1.714285714,0.52173913,,112.5,N,N,Y,,2,NORMAL,60,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,10/17/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,35,2.666666667,0.457142857,2.666666667,0.457142857,,36.5,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-7,10/17/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,,11,36,2.090909091,0.638888889,2.090909091,0.638888889,,31,N,N,Y,,4,NORMAL,23,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,11/7/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,4,0.3,3.4,5.4,1.264705882,0.796296296,1.176470588,0.740740741,Y,3.8,N,N,,,56,NORMAL,4.3,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,11/7/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,11/7/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,60,-4,35,115,1.6,0.486956522,1.714285714,0.52173913,,116.5,N,N,,,39,NORMAL,56,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,11/7/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,35,2.333333333,0.4,2.666666667,0.457142857,Y,38.5,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,11/7/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,23,-3,11,36,1.818181818,0.555555556,2.090909091,0.638888889,,34,N,N,,,41,NORMAL,20,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,33,11/25/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4,0.6,3.4,5.4,1.352941176,0.851851852,1.176470588,0.740740741,,3.5,N,N,,,90,NORMAL,4.6,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,33,11/25/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,5.13,8.55,-3.42,3,21,1.71,0.244285714,2.85,0.407142857,Y,26.37,N,N,,,78,NORMAL,5.13,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,33,11/25/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,60,-7,35,115,1.514285714,0.460869565,1.714285714,0.52173913,,119.5,N,N,,,74,NORMAL,53,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,33,11/25/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,35,2.333333333,0.4,2.666666667,0.457142857,,38.5,N,N,,,75,NORMAL,14,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,33,11/25/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,23,-2,11,36,1.909090909,0.583333333,2.090909091,0.638888889,,33,N,N,,,76,NORMAL,21,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,44,12/6/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.5,4,0.5,3.4,5.4,1.323529412,0.833333333,1.176470588,0.740740741,,3.6,N,N,,,120,NORMAL,4.5,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,44,12/6/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,108,NORMAL,10.26,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,44,12/6/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,60,-4,35,115,1.6,0.486956522,1.714285714,0.52173913,,116.5,N,N,,,104,NORMAL,56,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,44,12/6/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,16,4,6,35,3.333333333,0.571428571,2.666666667,0.457142857,,32.5,N,N,,,105,NORMAL,20,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,44,12/6/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,23,-4,11,36,1.727272727,0.527777778,2.090909091,0.638888889,Y,35,N,N,,,106,NORMAL,19,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,12/20/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,4,0.5,3.4,5.4,1.323529412,0.833333333,1.176470588,0.740740741,,3.6,N,N,,,150,NORMAL,4.5,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,12/20/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,12/20/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,60,-5,35,115,1.571428571,0.47826087,1.714285714,0.52173913,,117.5,N,N,,,134,NORMAL,55,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,12/20/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,0,6,35,2.666666667,0.457142857,2.666666667,0.457142857,,36.5,N,N,,,135,NORMAL,16,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,12/20/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,23,6,11,36,2.636363636,0.805555556,2.090909091,0.638888889,,25,N,N,,,136,NORMAL,29,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,62,12/24/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,Y,181,NORMAL,4.4,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,62,12/24/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,4,0.4,3.4,5.4,1.294117647,0.814814815,1.176470588,0.740740741,,3.7,N,N,,Y,181,NORMAL,4.4,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,62,12/24/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,168,NORMAL,8.55,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,62,12/24/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,Y,168,NORMAL,8.55,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,62,12/24/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,60,-10,35,115,1.428571429,0.434782609,1.714285714,0.52173913,Y,122.5,N,N,,Y,164,NORMAL,50,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,62,12/24/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,50,60,-10,35,115,1.428571429,0.434782609,1.714285714,0.52173913,Y,122.5,N,N,,Y,164,NORMAL,50,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,62,12/24/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,35,2.333333333,0.4,2.666666667,0.457142857,,38.5,N,N,,Y,165,NORMAL,14,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,62,12/24/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,35,2.333333333,0.4,2.666666667,0.457142857,,38.5,N,N,,Y,165,NORMAL,14,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,62,12/24/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,0,11,36,2.090909091,0.638888889,2.090909091,0.638888889,,31,N,N,,Y,166,NORMAL,23,0,No
CDISCPILOT01,1065,01-704-1065,Xanomeline High Dose,81,Xanomeline High Dose,81,10/24/13,12/22/13,75,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,62,12/24/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,0,11,36,2.090909091,0.638888889,2.090909091,0.638888889,,31,N,N,,Y,166,NORMAL,23,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-7,1/15/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-7,1/15/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-7,1/15/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,101,101,,35,115,2.885714286,0.87826087,2.885714286,0.87826087,,83.5,N,N,Y,,2,NORMAL,101,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-7,1/15/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,14,,6,32,2.333333333,0.4375,2.333333333,0.4375,,34,N,N,Y,,3,NORMAL,14,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-7,1/15/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,19,,9,34,2.111111111,0.558823529,2.111111111,0.558823529,,32,N,N,Y,,4,NORMAL,19,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,19,2/9/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,42,NORMAL,8.55,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,19,2/9/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,101,-10,35,115,2.6,0.791304348,2.885714286,0.87826087,,81.5,N,N,,,39,NORMAL,91,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,19,2/9/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,14,-2,6,32,2,0.375,2.333333333,0.4375,,36,N,N,,,40,NORMAL,12,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,19,2/9/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,19,8,9,34,3,0.794117647,2.111111111,0.558823529,,24,N,N,,,41,NORMAL,27,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,32,2/22/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.5,4.1,-0.6,3.4,5.4,1.029411765,0.648148148,1.205882353,0.759259259,Y,4.6,N,N,,,70,NORMAL,3.5,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,32,2/22/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,58,NORMAL,6.84,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,32,2/22/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,100,101,-1,35,115,2.857142857,0.869565217,2.885714286,0.87826087,,82.5,N,N,,,54,NORMAL,100,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,32,2/22/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,14,-1,6,32,2.166666667,0.40625,2.333333333,0.4375,,35,N,N,,,55,NORMAL,13,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,32,2/22/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,19,2,9,34,2.333333333,0.617647059,2.111111111,0.558823529,Y,30,N,N,,,56,NORMAL,21,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,47,3/9/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,,,100,NORMAL,4.1,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,47,3/9/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,88,NORMAL,6.84,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,47,3/9/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,97,101,-4,35,115,2.771428571,0.843478261,2.885714286,0.87826087,,79.5,N,N,,,84,NORMAL,97,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,47,3/9/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,14,-3,6,32,1.833333333,0.34375,2.333333333,0.4375,Y,37,N,N,,,85,NORMAL,11,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,47,3/9/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,19,3,9,34,2.444444444,0.647058824,2.111111111,0.558823529,,29,N,N,,,86,NORMAL,22,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,69,3/31/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.2,4.1,0.1,3.4,5.4,1.235294118,0.777777778,1.205882353,0.759259259,,3.9,N,N,,Y,131,NORMAL,4.2,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,69,3/31/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.2,4.1,0.1,3.4,5.4,1.235294118,0.777777778,1.205882353,0.759259259,,3.9,N,N,,Y,131,NORMAL,4.2,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,69,3/31/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,118,NORMAL,10.26,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,69,3/31/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,118,NORMAL,10.26,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,69,3/31/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,101,-15,35,115,2.457142857,0.747826087,2.885714286,0.87826087,Y,86.5,N,N,,Y,114,NORMAL,86,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,69,3/31/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,101,-15,35,115,2.457142857,0.747826087,2.885714286,0.87826087,Y,86.5,N,N,,Y,114,NORMAL,86,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,69,3/31/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,14,-3,6,32,1.833333333,0.34375,2.333333333,0.4375,,37,N,N,,Y,115,NORMAL,11,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,69,3/31/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,14,-3,6,32,1.833333333,0.34375,2.333333333,0.4375,,37,N,N,,Y,115,NORMAL,11,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,69,3/31/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,19,5,9,34,2.666666667,0.705882353,2.111111111,0.558823529,,27,N,N,,Y,116,NORMAL,24,0,No
CDISCPILOT01,1074,01-704-1074,Xanomeline High Dose,81,Xanomeline High Dose,81,1/22/14,3/20/14,80,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,69,3/31/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,19,5,9,34,2.666666667,0.705882353,2.111111111,0.558823529,,27,N,N,,Y,116,NORMAL,24,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-43,1/31/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,19,NORMAL,4.6,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-43,1/31/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-43,1/31/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,58,,35,115,1.657142857,0.504347826,1.657142857,0.504347826,,114.5,N,N,Y,,2,NORMAL,58,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-43,1/31/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,22,,6,35,3.666666667,0.628571429,3.666666667,0.628571429,,30.5,N,N,Y,,3,NORMAL,22,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-43,1/31/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,11,36,1.818181818,0.555555556,1.818181818,0.555555556,,34,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-21,2/22/13,UNSCHEDULED 1.1,1.1,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,56,NORMAL,4.5,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-21,2/22/13,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,17.1,10.26,6.84,3,21,5.7,0.814285714,3.42,0.488571429,,15.6,N,N,,,43,NORMAL,17.1,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-21,2/22/13,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,58,58,0,35,115,1.657142857,0.504347826,1.657142857,0.504347826,,114.5,N,N,,,39,NORMAL,58,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-21,2/22/13,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,22,-5,6,35,2.833333333,0.485714286,3.666666667,0.628571429,,35.5,N,N,,,40,NORMAL,17,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-21,2/22/13,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,10,20,-10,11,36,0.909090909,0.277777778,1.818181818,0.555555556,,44,N,N,,,41,LOW,10,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-13,3/2/13,UNSCHEDULED 1.2,1.2,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,79,NORMAL,10.26,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-13,3/2/13,UNSCHEDULED 1.2,1.2,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,58,-1,35,115,1.628571429,0.495652174,1.657142857,0.504347826,,115.5,N,N,,,76,NORMAL,57,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-13,3/2/13,UNSCHEDULED 1.2,1.2,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,22,-8,6,35,2.333333333,0.4,3.666666667,0.628571429,,38.5,N,N,,,77,NORMAL,14,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, .,,-13,3/2/13,UNSCHEDULED 1.2,1.2,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,11,36,1.636363636,0.5,1.818181818,0.555555556,,36,N,N,,,78,NORMAL,18,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/30/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,4.6,0.2,3.4,5.4,1.411764706,0.888888889,1.352941176,0.851851852,,3.3,N,N,,,114,NORMAL,4.8,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/30/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,101,NORMAL,10.26,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/30/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,58,23,35,115,2.314285714,0.704347826,1.657142857,0.504347826,,91.5,N,N,,,97,NORMAL,81,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/30/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,22,4,6,35,4.333333333,0.742857143,3.666666667,0.628571429,,26.5,N,N,,,98,NORMAL,26,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,16,3/30/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,11,36,1.636363636,0.5,1.818181818,0.555555556,,36,N,N,,,99,NORMAL,18,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,29,4/12/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.6,-0.5,3.4,5.4,1.205882353,0.759259259,1.352941176,0.851851852,,4,N,N,,,148,NORMAL,4.1,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,29,4/12/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,Y,22.95,N,N,,,136,NORMAL,8.55,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,29,4/12/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,58,7,35,115,1.857142857,0.565217391,1.657142857,0.504347826,Y,107.5,N,N,,,132,NORMAL,65,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,29,4/12/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,22,-4,6,35,3,0.514285714,3.666666667,0.628571429,,34.5,N,N,,,133,NORMAL,18,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,29,4/12/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,11,36,1.636363636,0.5,1.818181818,0.555555556,,36,N,N,,,134,NORMAL,18,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,4/25/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,178,NORMAL,4.5,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,4/25/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,,166,NORMAL,8.55,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,4/25/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,58,15,35,115,2.085714286,0.634782609,1.657142857,0.504347826,,99.5,N,N,,,162,NORMAL,73,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,4/25/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,22,-8,6,35,2.333333333,0.4,3.666666667,0.628571429,Y,38.5,N,N,,,163,NORMAL,14,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,42,4/25/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,20,-4,11,36,1.454545455,0.444444444,1.818181818,0.555555556,,38,N,N,,,164,NORMAL,16,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,5/11/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,208,NORMAL,4.5,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,5/11/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,196,NORMAL,11.97,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,5/11/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,58,21,35,115,2.257142857,0.686956522,1.657142857,0.504347826,,93.5,N,N,,,192,NORMAL,79,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,5/11/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,22,-6,6,35,2.666666667,0.457142857,3.666666667,0.628571429,,36.5,N,N,,,193,NORMAL,16,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,58,5/11/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,11,36,1.363636364,0.416666667,1.818181818,0.555555556,Y,39,N,N,,,194,NORMAL,15,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,85,6/7/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,239,NORMAL,4.5,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,85,6/7/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,226,NORMAL,10.26,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,85,6/7/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,58,17,35,115,2.142857143,0.652173913,1.657142857,0.504347826,,97.5,N,N,,,222,NORMAL,75,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,85,6/7/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,22,-3,6,35,3.166666667,0.542857143,3.666666667,0.628571429,,33.5,N,N,,,223,NORMAL,19,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,85,6/7/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,11,36,1.727272727,0.527777778,1.818181818,0.555555556,,35,N,N,,,224,NORMAL,19,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,98,6/20/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,4.6,-0.6,3.4,5.4,1.176470588,0.740740741,1.352941176,0.851851852,Y,4.1,N,N,,Y,274,NORMAL,4,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,98,6/20/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,4.6,-0.6,3.4,5.4,1.176470588,0.740740741,1.352941176,0.851851852,Y,4.1,N,N,,Y,274,NORMAL,4,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,98,6/20/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,Y,261,NORMAL,8.55,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,98,6/20/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,,22.95,N,N,,Y,261,NORMAL,8.55,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,98,6/20/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,58,15,35,115,2.085714286,0.634782609,1.657142857,0.504347826,,99.5,N,N,,Y,257,NORMAL,73,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,98,6/20/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,58,15,35,115,2.085714286,0.634782609,1.657142857,0.504347826,,99.5,N,N,,Y,257,NORMAL,73,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,98,6/20/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,22,-5,6,35,2.833333333,0.485714286,3.666666667,0.628571429,,35.5,N,N,,Y,258,NORMAL,17,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,98,6/20/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,22,-5,6,35,2.833333333,0.485714286,3.666666667,0.628571429,,35.5,N,N,,Y,258,NORMAL,17,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y, Week 16,16,98,6/20/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,20,-4,11,36,1.454545455,0.444444444,1.818181818,0.555555556,,38,N,N,,Y,259,NORMAL,16,0,No
CDISCPILOT01,1093,01-704-1093,Xanomeline High Dose,81,Xanomeline High Dose,81,3/15/13,6/17/13,79,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,98,6/20/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,20,-4,11,36,1.454545455,0.444444444,1.818181818,0.555555556,,38,N,N,,Y,259,NORMAL,16,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-14,1/9/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,19,NORMAL,4.6,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-14,1/9/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-14,1/9/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,74,,35,115,2.114285714,0.643478261,2.114285714,0.643478261,,98.5,N,N,Y,,2,NORMAL,74,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-14,1/9/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,,6,35,2.833333333,0.485714286,2.833333333,0.485714286,,35.5,N,N,Y,,3,NORMAL,17,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-14,1/9/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,,11,36,2.090909091,0.638888889,2.090909091,0.638888889,,31,N,N,Y,,4,NORMAL,23,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,12,2/3/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,,3.8,N,N,,,56,NORMAL,4.3,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,12,2/3/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,12,2/3/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,74,7,35,115,2.314285714,0.704347826,2.114285714,0.643478261,,91.5,N,N,,,39,NORMAL,81,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,12,2/3/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,17,3,6,35,3.333333333,0.571428571,2.833333333,0.485714286,,32.5,N,N,,,40,NORMAL,20,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,12,2/3/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,23,0,11,36,2.090909091,0.638888889,2.090909091,0.638888889,,31,N,N,,,41,NORMAL,23,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,2/18/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4,4.6,-0.6,3.4,5.4,1.176470588,0.740740741,1.352941176,0.851851852,,4.1,N,N,,,90,NORMAL,4,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,2/18/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,Y,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,2/18/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,74,5,35,115,2.257142857,0.686956522,2.114285714,0.643478261,,93.5,N,N,,,74,NORMAL,79,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,2/18/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,35,2.5,0.428571429,2.833333333,0.485714286,,37.5,N,N,,,75,NORMAL,15,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,2/18/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,23,-3,11,36,1.818181818,0.555555556,2.090909091,0.638888889,,34,N,N,,,76,NORMAL,20,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,50,3/13/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,,3.8,N,N,,,120,NORMAL,4.3,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,50,3/13/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,13.68,11.97,1.71,3,21,4.56,0.651428571,3.99,0.57,,17.82,N,N,,,108,NORMAL,13.68,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,50,3/13/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,74,2,35,115,2.171428571,0.660869565,2.114285714,0.643478261,,96.5,N,N,,,104,NORMAL,76,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,50,3/13/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,0,6,35,2.833333333,0.485714286,2.833333333,0.485714286,,35.5,N,N,,,105,NORMAL,17,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,50,3/13/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,23,-2,11,36,1.909090909,0.583333333,2.090909091,0.638888889,,33,N,N,,,106,NORMAL,21,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,63,3/26/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,150,NORMAL,4.4,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,63,3/26/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,,138,NORMAL,11.97,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,63,3/26/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,74,-2,35,115,2.057142857,0.626086957,2.114285714,0.643478261,,100.5,N,N,,,134,NORMAL,72,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,63,3/26/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,17,-4,6,35,2.166666667,0.371428571,2.833333333,0.485714286,,39.5,N,N,,,135,NORMAL,13,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,63,3/26/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,23,-4,11,36,1.727272727,0.527777778,2.090909091,0.638888889,Y,35,N,N,,,136,NORMAL,19,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,4/17/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,,181,NORMAL,4.2,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,4/17/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,168,NORMAL,10.26,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,4/17/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,74,7,35,115,2.314285714,0.704347826,2.114285714,0.643478261,,91.5,N,N,,,164,NORMAL,81,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,4/17/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,35,2.5,0.428571429,2.833333333,0.485714286,,37.5,N,N,,,165,NORMAL,15,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,85,4/17/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,23,-3,11,36,1.818181818,0.555555556,2.090909091,0.638888889,,34,N,N,,,166,NORMAL,20,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,5/14/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,4.6,-0.5,3.4,5.4,1.205882353,0.759259259,1.352941176,0.851851852,,4,N,N,,,215,NORMAL,4.1,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,5/14/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,203,NORMAL,10.26,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,5/14/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,74,5,35,115,2.257142857,0.686956522,2.114285714,0.643478261,,93.5,N,N,,,199,NORMAL,79,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,5/14/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,0,6,35,2.833333333,0.485714286,2.833333333,0.485714286,,35.5,N,N,,,200,NORMAL,17,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,112,5/14/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,23,-1,11,36,2,0.611111111,2.090909091,0.638888889,,32,N,N,,,201,NORMAL,22,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,145,6/16/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,3.9,4.6,-0.7,3.4,5.4,1.147058824,0.722222222,1.352941176,0.851851852,Y,4.2,N,N,,,245,NORMAL,3.9,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,145,6/16/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,,233,NORMAL,11.97,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,145,6/16/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,64,74,-10,35,115,1.828571429,0.556521739,2.114285714,0.643478261,Y,108.5,N,N,,,229,NORMAL,64,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,145,6/16/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,17,4,6,35,3.5,0.6,2.833333333,0.485714286,,31.5,N,N,,,230,NORMAL,21,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,145,6/16/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,23,-3,11,36,1.818181818,0.555555556,2.090909091,0.638888889,,34,N,N,,,231,NORMAL,20,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,167,7/8/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,Y,276,NORMAL,4.2,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,167,7/8/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,Y,276,NORMAL,4.2,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,167,7/8/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,Y,263,NORMAL,10.26,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,167,7/8/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,Y,263,NORMAL,10.26,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,167,7/8/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,74,2,35,115,2.171428571,0.660869565,2.114285714,0.643478261,,96.5,N,N,,Y,259,NORMAL,76,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,167,7/8/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,74,2,35,115,2.171428571,0.660869565,2.114285714,0.643478261,,96.5,N,N,,Y,259,NORMAL,76,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,167,7/8/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,35,2,0.342857143,2.833333333,0.485714286,Y,40.5,N,N,,Y,260,NORMAL,12,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,167,7/8/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,35,2,0.342857143,2.833333333,0.485714286,Y,40.5,N,N,,Y,260,NORMAL,12,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,167,7/8/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,23,-3,11,36,1.818181818,0.555555556,2.090909091,0.638888889,,34,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1114,01-704-1114,Xanomeline Low Dose,54,Xanomeline Low Dose,54,1/23/13,7/7/13,77,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,167,7/8/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,23,-3,11,36,1.818181818,0.555555556,2.090909091,0.638888889,,34,N,N,,Y,261,NORMAL,20,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-15,11/17/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-15,11/17/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-15,11/17/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,78,78,,35,115,2.228571429,0.67826087,2.228571429,0.67826087,,94.5,N,N,Y,,2,NORMAL,78,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-15,11/17/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,,6,32,2.833333333,0.53125,2.833333333,0.53125,,31,N,N,Y,,3,NORMAL,17,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-15,11/17/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,14,12/15/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,3.9,4.5,-0.6,3.4,5.4,1.147058824,0.722222222,1.323529412,0.833333333,,4.2,N,N,,,56,NORMAL,3.9,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,14,12/15/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,43,NORMAL,6.84,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,14,12/15/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,78,-9,35,115,1.971428571,0.6,2.228571429,0.67826087,Y,103.5,N,N,,,39,NORMAL,69,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,14,12/15/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,17,-4,6,32,2.166666667,0.40625,2.833333333,0.53125,,35,N,N,,,40,NORMAL,13,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 2,2,14,12/15/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,Y,36,N,N,,,41,NORMAL,15,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,12/29/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,90,NORMAL,4.1,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,12/29/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,12/29/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,78,-5,35,115,2.085714286,0.634782609,2.228571429,0.67826087,,99.5,N,N,,,74,NORMAL,73,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,12/29/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,32,2,0.375,2.833333333,0.53125,Y,36,N,N,,,75,NORMAL,12,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,12/29/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,9,34,2.111111111,0.558823529,2.222222222,0.588235294,,32,N,N,,,76,NORMAL,19,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,43,1/13/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,3.8,4.5,-0.7,3.4,5.4,1.117647059,0.703703704,1.323529412,0.833333333,Y,4.3,N,N,,,120,NORMAL,3.8,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,43,1/13/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,11.97,8.55,3.42,3,21,3.99,0.57,2.85,0.407142857,,19.53,N,N,,,108,NORMAL,11.97,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,43,1/13/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,78,5,35,115,2.371428571,0.72173913,2.228571429,0.67826087,,89.5,N,N,,,104,NORMAL,83,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,43,1/13/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,33,17,16,6,32,5.5,1.03125,2.833333333,0.53125,,30,N,N,,,105,HIGH,33,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 6,6,43,1/13/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,20,12,9,34,3.555555556,0.941176471,2.222222222,0.588235294,,27.5,N,N,,,106,NORMAL,32,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,57,1/27/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4,4.5,-0.5,3.4,5.4,1.176470588,0.740740741,1.323529412,0.833333333,,4.1,N,N,,,149,NORMAL,4,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,57,1/27/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,18.81,8.55,10.26,3,21,6.27,0.895714286,2.85,0.407142857,,17.31,N,N,,,138,NORMAL,18.81,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,57,1/27/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,90,78,12,35,115,2.571428571,0.782608696,2.228571429,0.67826087,,82.5,N,N,,,134,NORMAL,90,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,57,1/27/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,17,7,6,32,4,0.75,2.833333333,0.53125,,24,N,N,,,135,NORMAL,24,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 8,8,57,1/27/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,9,34,2,0.529411765,2.222222222,0.588235294,,33,N,N,,,136,NORMAL,18,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 12,12,64,2/3/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.8,4.5,-0.7,3.4,5.4,1.117647059,0.703703704,1.323529412,0.833333333,,4.3,N,N,,Y,178,NORMAL,3.8,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,64,2/3/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.8,4.5,-0.7,3.4,5.4,1.117647059,0.703703704,1.323529412,0.833333333,,4.3,N,N,,Y,178,NORMAL,3.8,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 12,12,64,2/3/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,165,NORMAL,10.26,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,64,2/3/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,165,NORMAL,10.26,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 12,12,64,2/3/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,78,-8,35,115,2,0.608695652,2.228571429,0.67826087,,102.5,N,N,,Y,161,NORMAL,70,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,64,2/3/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,70,78,-8,35,115,2,0.608695652,2.228571429,0.67826087,,102.5,N,N,,Y,161,NORMAL,70,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 12,12,64,2/3/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,32,2,0.375,2.833333333,0.53125,,36,N,N,,Y,162,NORMAL,12,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,64,2/3/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,32,2,0.375,2.833333333,0.53125,,36,N,N,,Y,162,NORMAL,12,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y, Week 12,12,64,2/3/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,,36,N,N,,Y,163,NORMAL,15,0,No
CDISCPILOT01,1120,01-704-1120,Xanomeline Low Dose,54,Xanomeline Low Dose,54,12/2/13,2/1/14,71,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,64,2/3/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,,36,N,N,,Y,163,NORMAL,15,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-16,9/16/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-16,9/16/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-16,9/16/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,75,,35,115,2.142857143,0.652173913,2.142857143,0.652173913,,97.5,N,N,Y,,2,NORMAL,75,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-16,9/16/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,21,,6,32,3.5,0.65625,3.5,0.65625,,27,N,N,Y,,3,NORMAL,21,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-16,9/16/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,35,35,,9,34,3.888888889,1.029411765,3.888888889,1.029411765,,30.5,N,N,Y,,4,HIGH,35,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,10/16/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,56,NORMAL,4.1,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,10/16/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,10/16/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,75,-10,35,115,1.857142857,0.565217391,2.142857143,0.652173913,,107.5,N,N,,,39,NORMAL,65,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,10/16/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,21,-4,6,32,2.833333333,0.53125,3.5,0.65625,Y,31,N,N,,,40,NORMAL,17,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,10/16/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,35,-6,9,34,3.222222222,0.852941176,3.888888889,1.029411765,,24.5,N,N,,,41,NORMAL,29,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/30/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,90,NORMAL,4.1,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/30/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,Y,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/30/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,75,-6,35,115,1.971428571,0.6,2.142857143,0.652173913,,103.5,N,N,,,74,NORMAL,69,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/30/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,21,-1,6,32,3.333333333,0.625,3.5,0.65625,,28,N,N,,,75,NORMAL,20,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 4,4,29,10/30/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,35,-7,9,34,3.111111111,0.823529412,3.888888889,1.029411765,,23.5,N,N,,,76,NORMAL,28,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,11/13/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4,4.5,-0.5,3.4,5.4,1.176470588,0.740740741,1.323529412,0.833333333,,4.1,N,N,,,120,NORMAL,4,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,11/13/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,,24.66,N,N,,,108,NORMAL,6.84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,11/13/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,75,-8,35,115,1.914285714,0.582608696,2.142857143,0.652173913,,105.5,N,N,,,104,NORMAL,67,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,11/13/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,21,-1,6,32,3.333333333,0.625,3.5,0.65625,,28,N,N,,,105,NORMAL,20,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 6,6,43,11/13/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,35,-6,9,34,3.222222222,0.852941176,3.888888889,1.029411765,,24.5,N,N,,,106,NORMAL,29,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,56,11/26/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,150,NORMAL,4.1,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,56,11/26/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,56,11/26/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,65,75,-10,35,115,1.857142857,0.565217391,2.142857143,0.652173913,,107.5,N,N,,,134,NORMAL,65,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,56,11/26/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,21,-1,6,32,3.333333333,0.625,3.5,0.65625,,28,N,N,,,135,NORMAL,20,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 8,8,56,11/26/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,35,-4,9,34,3.444444444,0.911764706,3.888888889,1.029411765,,26.5,N,N,,,136,NORMAL,31,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/25/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,4.5,-0.6,3.4,5.4,1.147058824,0.722222222,1.323529412,0.833333333,Y,4.2,N,N,,,181,NORMAL,3.9,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/25/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,168,NORMAL,10.26,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/25/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,75,1,35,115,2.171428571,0.660869565,2.142857143,0.652173913,,96.5,N,N,,,164,NORMAL,76,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/25/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,21,-2,6,32,3.166666667,0.59375,3.5,0.65625,,29,N,N,,,165,NORMAL,19,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,12/25/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,35,-4,9,34,3.444444444,0.911764706,3.888888889,1.029411765,,26.5,N,N,,,166,NORMAL,31,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,112,1/21/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,,215,NORMAL,4.3,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,112,1/21/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,,24.66,N,N,,,203,NORMAL,6.84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,112,1/21/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,75,-8,35,115,1.914285714,0.582608696,2.142857143,0.652173913,,105.5,N,N,,,199,NORMAL,67,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,112,1/21/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,21,5,6,32,4.333333333,0.8125,3.5,0.65625,,23,N,N,,,200,NORMAL,26,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 16,16,112,1/21/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,36,35,1,9,34,4,1.058823529,3.888888889,1.029411765,Y,31.5,N,N,,,201,HIGH,36,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,139,2/17/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4,4.5,-0.5,3.4,5.4,1.176470588,0.740740741,1.323529412,0.833333333,,4.1,N,N,,,245,NORMAL,4,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,139,2/17/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,,24.66,N,N,,,233,NORMAL,6.84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,139,2/17/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,75,-15,35,115,1.714285714,0.52173913,2.142857143,0.652173913,Y,112.5,N,N,,,229,NORMAL,60,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,139,2/17/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,32,3,0.5625,3.5,0.65625,,30,N,N,,,230,NORMAL,18,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 20,20,139,2/17/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,35,-4,9,34,3.444444444,0.911764706,3.888888889,1.029411765,,26.5,N,N,,,231,NORMAL,31,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,167,3/17/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.5,-0.3,3.4,5.4,1.235294118,0.777777778,1.323529412,0.833333333,,3.9,N,N,,Y,276,NORMAL,4.2,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,167,3/17/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.2,4.5,-0.3,3.4,5.4,1.235294118,0.777777778,1.323529412,0.833333333,,3.9,N,N,,Y,276,NORMAL,4.2,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,167,3/17/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,,24.66,N,N,,Y,263,NORMAL,6.84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,167,3/17/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,6.84,11.97,-5.13,3,21,2.28,0.325714286,3.99,0.57,,24.66,N,N,,Y,263,NORMAL,6.84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,167,3/17/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,75,2,35,115,2.2,0.669565217,2.142857143,0.652173913,,95.5,N,N,,Y,259,NORMAL,77,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,167,3/17/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,75,2,35,115,2.2,0.669565217,2.142857143,0.652173913,,95.5,N,N,,Y,259,NORMAL,77,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,167,3/17/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,32,3,0.5625,3.5,0.65625,,30,N,N,,Y,260,NORMAL,18,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,167,3/17/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,21,-3,6,32,3,0.5625,3.5,0.65625,,30,N,N,,Y,260,NORMAL,18,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 24,24,167,3/17/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,35,-10,9,34,2.777777778,0.735294118,3.888888889,1.029411765,,26,N,N,,Y,261,NORMAL,25,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,167,3/17/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,35,-10,9,34,2.777777778,0.735294118,3.888888889,1.029411765,,26,N,N,,Y,261,NORMAL,25,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,181,3/31/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,,310,NORMAL,4.3,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,181,3/31/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,298,NORMAL,8.55,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,181,3/31/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,75,9,35,115,2.4,0.730434783,2.142857143,0.652173913,,88.5,N,N,,,294,NORMAL,84,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,181,3/31/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,21,-6,6,32,2.5,0.46875,3.5,0.65625,,33,N,N,,,295,NORMAL,15,0,No
CDISCPILOT01,1127,01-704-1127,Placebo,0,Placebo,0,10/2/13,3/31/14,84,>80,3,WHITE,1,F,Y,,Y, Week 26,26,181,3/31/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,35,-7,9,34,3.111111111,0.823529412,3.888888889,1.029411765,,23.5,N,N,,,296,NORMAL,28,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-8,10/23/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,19,NORMAL,4.6,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-8,10/23/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-8,10/23/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,99,99,,35,115,2.828571429,0.860869565,2.828571429,0.860869565,,81.5,N,N,Y,,2,NORMAL,99,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-8,10/23/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,32,2.666666667,0.5,2.666666667,0.5,,32,N,N,Y,,3,NORMAL,16,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-8,10/23/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,16,,9,34,1.777777778,0.470588235,1.777777778,0.470588235,,35,N,N,Y,,4,NORMAL,16,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,11/14/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,,56,NORMAL,4.2,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,11/14/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,11/14/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,99,-7,35,115,2.628571429,0.8,2.828571429,0.860869565,,80.5,N,N,,,39,NORMAL,92,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,11/14/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,16,1,6,32,2.833333333,0.53125,2.666666667,0.5,,31,N,N,,,40,NORMAL,17,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,15,11/14/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,16,-1,9,34,1.666666667,0.441176471,1.777777778,0.470588235,,36,N,N,,,41,NORMAL,15,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,11/26/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,,3.8,N,N,,,90,NORMAL,4.3,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,11/26/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,10.26,-1.71,3,21,2.85,0.407142857,3.42,0.488571429,Y,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,11/26/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,99,-10,35,115,2.542857143,0.773913043,2.828571429,0.860869565,,83.5,N,N,,,74,NORMAL,89,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,11/26/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,32,2.5,0.46875,2.666666667,0.5,,33,N,N,,,75,NORMAL,15,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,27,11/26/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,16,-3,9,34,1.444444444,0.382352941,1.777777778,0.470588235,Y,38,N,N,,,76,NORMAL,13,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,12/11/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4,4.6,-0.6,3.4,5.4,1.176470588,0.740740741,1.352941176,0.851851852,,4.1,N,N,,,120,NORMAL,4,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,12/11/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,,108,NORMAL,11.97,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,12/11/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,91,99,-8,35,115,2.6,0.791304348,2.828571429,0.860869565,,81.5,N,N,,,104,NORMAL,91,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,12/11/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,32,3,0.5625,2.666666667,0.5,,30,N,N,,,105,NORMAL,18,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,42,12/11/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,16,3,9,34,2.111111111,0.558823529,1.777777778,0.470588235,,32,N,N,,,106,NORMAL,19,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,12/25/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,150,NORMAL,4.4,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,12/25/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,17.1,10.26,6.84,3,21,5.7,0.814285714,3.42,0.488571429,,15.6,N,N,,,138,NORMAL,17.1,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,12/25/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,89,99,-10,35,115,2.542857143,0.773913043,2.828571429,0.860869565,,83.5,N,N,,,134,NORMAL,89,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,12/25/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,16,2,6,32,3,0.5625,2.666666667,0.5,,30,N,N,,,135,NORMAL,18,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,56,12/25/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,16,2,9,34,2,0.529411765,1.777777778,0.470588235,,33,N,N,,,136,NORMAL,18,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,1/22/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.7,4.6,-0.9,3.4,5.4,1.088235294,0.685185185,1.352941176,0.851851852,Y,4.4,N,N,,,182,NORMAL,3.7,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,1/22/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,15.39,10.26,5.13,3,21,5.13,0.732857143,3.42,0.488571429,,16.11,N,N,,,169,NORMAL,15.39,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,1/22/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,99,-11,35,115,2.514285714,0.765217391,2.828571429,0.860869565,,84.5,N,N,,,164,NORMAL,88,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,1/22/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,32,2.333333333,0.4375,2.666666667,0.5,,34,N,N,,,165,NORMAL,14,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,84,1/22/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,16,1,9,34,1.888888889,0.5,1.777777778,0.470588235,,34,N,N,,,167,NORMAL,17,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,2/19/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.1,4.6,-0.5,3.4,5.4,1.205882353,0.759259259,1.352941176,0.851851852,,4,N,N,,,216,NORMAL,4.1,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,2/19/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,204,NORMAL,10.26,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,2/19/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,83,99,-16,35,115,2.371428571,0.72173913,2.828571429,0.860869565,Y,89.5,N,N,,,200,NORMAL,83,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,2/19/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,16,-2,6,32,2.333333333,0.4375,2.666666667,0.5,,34,N,N,,,201,NORMAL,14,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,112,2/19/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,16,-3,9,34,1.444444444,0.382352941,1.777777778,0.470588235,,38,N,N,,,202,NORMAL,13,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,147,3/26/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,247,NORMAL,4.5,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,147,3/26/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,13.68,10.26,3.42,3,21,4.56,0.651428571,3.42,0.488571429,,17.82,N,N,,,234,NORMAL,13.68,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,147,3/26/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,92,99,-7,35,115,2.628571429,0.8,2.828571429,0.860869565,,80.5,N,N,,,230,NORMAL,92,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,147,3/26/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,16,-3,6,32,2.166666667,0.40625,2.666666667,0.5,Y,35,N,N,,,231,NORMAL,13,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,147,3/26/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,16,-2,9,34,1.555555556,0.411764706,1.777777778,0.470588235,,37,N,N,,,232,NORMAL,14,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,183,5/1/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.6,0,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,,Y,284,NORMAL,4.6,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,183,5/1/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.6,4.6,0,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,,Y,284,NORMAL,4.6,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,183,5/1/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,Y,271,NORMAL,11.97,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,183,5/1/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,10.26,1.71,3,21,3.99,0.57,3.42,0.488571429,,19.53,N,N,,Y,271,NORMAL,11.97,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,183,5/1/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,94,99,-5,35,115,2.685714286,0.817391304,2.828571429,0.860869565,,78.5,N,N,,Y,267,NORMAL,94,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,183,5/1/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,94,99,-5,35,115,2.685714286,0.817391304,2.828571429,0.860869565,,78.5,N,N,,Y,267,NORMAL,94,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,183,5/1/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,16,3,6,32,3.166666667,0.59375,2.666666667,0.5,,29,N,N,,Y,268,NORMAL,19,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,183,5/1/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,16,3,6,32,3.166666667,0.59375,2.666666667,0.5,,29,N,N,,Y,268,NORMAL,19,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,183,5/1/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,16,2,9,34,2,0.529411765,1.777777778,0.470588235,,33,N,N,,Y,269,NORMAL,18,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,183,5/1/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,16,2,9,34,2,0.529411765,1.777777778,0.470588235,,33,N,N,,Y,269,NORMAL,18,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,5/16/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.8,4.6,0.2,3.4,5.4,1.411764706,0.888888889,1.352941176,0.851851852,,3.3,N,N,,,318,NORMAL,4.8,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,5/16/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,0,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,,,306,NORMAL,10.26,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,5/16/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,97,99,-2,35,115,2.771428571,0.843478261,2.828571429,0.860869565,,79.5,N,N,,,302,NORMAL,97,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,5/16/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,16,-1,6,32,2.5,0.46875,2.666666667,0.5,,33,N,N,,,303,NORMAL,15,0,No
CDISCPILOT01,1135,01-704-1135,Xanomeline Low Dose,54,Xanomeline Low Dose,54,10/31/13,5/16/14,74,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,5/16/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,16,-2,9,34,1.555555556,0.411764706,1.777777778,0.470588235,,37,N,N,,,304,NORMAL,14,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-20,8/30/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-20,8/30/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-20,8/30/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,Y,,2,NORMAL,61,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-20,8/30/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,7,,6,34,1.166666667,0.205882353,1.166666667,0.205882353,,44,N,N,Y,,3,NORMAL,7,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Baseline,0,-20,8/30/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,15,,9,34,1.666666667,0.441176471,1.666666667,0.441176471,,36,N,N,Y,,4,NORMAL,15,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/4/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4,4.3,-0.3,3.4,5.4,1.176470588,0.740740741,1.264705882,0.796296296,Y,4.1,N,N,,,56,NORMAL,4,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/4/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,13.68,8.55,5.13,3,21,4.56,0.651428571,2.85,0.407142857,,17.82,N,N,,,43,NORMAL,13.68,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/4/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,72,61,11,35,115,2.057142857,0.626086957,1.742857143,0.530434783,,100.5,N,N,,,39,NORMAL,72,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/4/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,7,0,6,34,1.166666667,0.205882353,1.166666667,0.205882353,,44,N,N,,,40,NORMAL,7,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 2,2,16,10/4/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,15,3,9,34,2,0.529411765,1.666666667,0.441176471,,33,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,33,10/21/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.6,4.3,0.3,3.4,5.4,1.352941176,0.851851852,1.264705882,0.796296296,,3.5,N,N,,,90,NORMAL,4.6,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,33,10/21/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,Y,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,33,10/21/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,61,-6,35,115,1.571428571,0.47826087,1.742857143,0.530434783,,117.5,N,N,,,74,NORMAL,55,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,33,10/21/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,6,7,-1,6,34,1,0.176470588,1.166666667,0.205882353,Y,45,N,N,,,75,NORMAL,6,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 4,4,33,10/21/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,9,34,1.444444444,0.382352941,1.666666667,0.441176471,Y,38,N,N,,,76,NORMAL,13,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,11/1/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,,120,NORMAL,4.1,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,11/1/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,11/1/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,54,61,-7,35,115,1.542857143,0.469565217,1.742857143,0.530434783,,118.5,N,N,,,104,NORMAL,54,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,11/1/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,7,0,6,34,1.166666667,0.205882353,1.166666667,0.205882353,,44,N,N,,,105,NORMAL,7,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 6,6,44,11/1/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,9,34,1.555555556,0.411764706,1.666666667,0.441176471,,37,N,N,,,106,NORMAL,14,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,11/15/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4,4.3,-0.3,3.4,5.4,1.176470588,0.740740741,1.264705882,0.796296296,,4.1,N,N,,,150,NORMAL,4,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,11/15/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,138,NORMAL,8.55,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,11/15/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,61,-4,35,115,1.628571429,0.495652174,1.742857143,0.530434783,,115.5,N,N,,,134,NORMAL,57,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,11/15/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,7,0,6,34,1.166666667,0.205882353,1.166666667,0.205882353,,44,N,N,,,135,NORMAL,7,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 8,8,58,11/15/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,15,3,9,34,2,0.529411765,1.666666667,0.441176471,,33,N,N,,,136,NORMAL,18,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,89,12/16/12,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4,4.3,-0.3,3.4,5.4,1.176470588,0.740740741,1.264705882,0.796296296,,4.1,N,N,,,181,NORMAL,4,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,89,12/16/12,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,0,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,,,168,NORMAL,8.55,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,89,12/16/12,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,61,-9,35,115,1.485714286,0.452173913,1.742857143,0.530434783,Y,120.5,N,N,,,164,NORMAL,52,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,89,12/16/12,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,7,6,6,34,2.166666667,0.382352941,1.166666667,0.205882353,,38,N,N,,,165,NORMAL,13,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 12,12,89,12/16/12,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,15,2,9,34,1.888888889,0.5,1.666666667,0.441176471,,34,N,N,,,166,NORMAL,17,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,118,1/14/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,5,4.3,0.7,3.4,5.4,1.470588235,0.925925926,1.264705882,0.796296296,,3.3,N,N,,,215,NORMAL,5,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,118,1/14/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,6.84,8.55,-1.71,3,21,2.28,0.325714286,2.85,0.407142857,,24.66,N,N,,,203,NORMAL,6.84,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,118,1/14/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,61,-8,35,115,1.514285714,0.460869565,1.742857143,0.530434783,,119.5,N,N,,,199,NORMAL,53,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,118,1/14/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,7,2,6,34,1.5,0.264705882,1.166666667,0.205882353,,42,N,N,,,200,NORMAL,9,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 16,16,118,1/14/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,9,34,1.444444444,0.382352941,1.666666667,0.441176471,,38,N,N,,,201,NORMAL,13,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,149,2/14/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.9,4.3,0.6,3.4,5.4,1.441176471,0.907407407,1.264705882,0.796296296,,3.2,N,N,,,245,NORMAL,4.9,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,149,2/14/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,13.68,8.55,5.13,3,21,4.56,0.651428571,2.85,0.407142857,,17.82,N,N,,,233,NORMAL,13.68,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,149,2/14/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,54,61,-7,35,115,1.542857143,0.469565217,1.742857143,0.530434783,,118.5,N,N,,,229,NORMAL,54,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,149,2/14/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,7,3,6,34,1.666666667,0.294117647,1.166666667,0.205882353,,41,N,N,,,230,NORMAL,10,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 20,20,149,2/14/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,9,34,1.444444444,0.382352941,1.666666667,0.441176471,,38,N,N,,,231,NORMAL,13,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,180,3/17/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,Y,277,NORMAL,4.5,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,180,3/17/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.5,4.3,0.2,3.4,5.4,1.323529412,0.833333333,1.264705882,0.796296296,,3.6,N,N,,Y,277,NORMAL,4.5,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,180,3/17/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,264,NORMAL,10.26,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,180,3/17/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,Y,264,NORMAL,10.26,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,180,3/17/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,61,-8,35,115,1.514285714,0.460869565,1.742857143,0.530434783,,119.5,N,N,,Y,259,NORMAL,53,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,180,3/17/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,61,-8,35,115,1.514285714,0.460869565,1.742857143,0.530434783,,119.5,N,N,,Y,259,NORMAL,53,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,180,3/17/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,7,0,6,34,1.166666667,0.205882353,1.166666667,0.205882353,,44,N,N,,Y,260,NORMAL,7,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,180,3/17/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,7,7,0,6,34,1.166666667,0.205882353,1.166666667,0.205882353,,44,N,N,,Y,260,NORMAL,7,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 24,24,180,3/17/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,9,34,1.444444444,0.382352941,1.666666667,0.441176471,,38,N,N,,Y,262,NORMAL,13,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y,End of Treatment,99,180,3/17/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,13,15,-2,9,34,1.444444444,0.382352941,1.666666667,0.441176471,,38,N,N,,Y,262,NORMAL,13,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,4/4/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,5.1,4.3,0.8,3.4,5.4,1.5,0.944444444,1.264705882,0.796296296,,3.4,N,N,,,313,NORMAL,5.1,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,4/4/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,10.26,8.55,1.71,3,21,3.42,0.488571429,2.85,0.407142857,,21.24,N,N,,,301,NORMAL,10.26,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,4/4/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,61,6,35,115,1.914285714,0.582608696,1.742857143,0.530434783,,105.5,N,N,,,296,NORMAL,67,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,4/4/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,6,7,-1,6,34,1,0.176470588,1.166666667,0.205882353,,45,N,N,,,297,NORMAL,6,0,No
CDISCPILOT01,1164,01-704-1164,Placebo,0,Placebo,0,9/19/12,4/4/13,67,65-80,2,WHITE,1,F,Y,,Y, Week 26,26,198,4/4/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,15,-1,9,34,1.555555556,0.411764706,1.666666667,0.441176471,,37,N,N,,,299,NORMAL,14,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-64,9/16/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,5.2,5.2,,3.4,5.4,1.529411765,0.962962963,1.529411765,0.962962963,,3.5,N,N,Y,,19,NORMAL,5.2,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-64,9/16/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-64,9/16/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,97,97,,35,115,2.771428571,0.843478261,2.771428571,0.843478261,,79.5,N,N,Y,,2,NORMAL,97,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-64,9/16/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,,6,32,3.166666667,0.59375,3.166666667,0.59375,,29,N,N,Y,,3,NORMAL,19,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Baseline,0,-64,9/16/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,9,34,2.222222222,0.588235294,2.222222222,0.588235294,,31,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-39,10/11/12,UNSCHEDULED 1.1,1.1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,42,NORMAL,13.68,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-39,10/11/12,UNSCHEDULED 1.1,1.1,Alkaline Phosphatase (U/L),ALP,22,CHEM,93,97,-4,35,115,2.657142857,0.808695652,2.771428571,0.843478261,,79.5,N,N,,,39,NORMAL,93,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-39,10/11/12,UNSCHEDULED 1.1,1.1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,19,-6,6,32,2.166666667,0.40625,3.166666667,0.59375,,35,N,N,,,40,NORMAL,13,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-39,10/11/12,UNSCHEDULED 1.1,1.1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,41,NORMAL,17,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-8,11/11/12,UNSCHEDULED 1.2,1.2,Potassium (mmol/L),K,19,CHEM,4,5.2,-1.2,3.4,5.4,1.176470588,0.740740741,1.529411765,0.962962963,,4.1,N,N,,,72,NORMAL,4,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-8,11/11/12,UNSCHEDULED 1.2,1.2,Bilirubin (umol/L),BILI,21,CHEM,18.81,13.68,5.13,3,21,6.27,0.895714286,4.56,0.651428571,,17.31,N,N,,,59,NORMAL,18.81,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-8,11/11/12,UNSCHEDULED 1.2,1.2,Alkaline Phosphatase (U/L),ALP,22,CHEM,100,97,3,35,115,2.857142857,0.869565217,2.771428571,0.843478261,,82.5,N,N,,,55,NORMAL,100,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-8,11/11/12,UNSCHEDULED 1.2,1.2,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,19,-8,6,32,1.833333333,0.34375,3.166666667,0.59375,,37,N,N,,,56,NORMAL,11,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, .,,-8,11/11/12,UNSCHEDULED 1.2,1.2,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,57,NORMAL,17,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,12/3/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,5.2,-1,3.4,5.4,1.235294118,0.777777778,1.529411765,0.962962963,,3.9,N,N,,,109,NORMAL,4.2,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,12/3/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,18.81,13.68,5.13,3,21,6.27,0.895714286,4.56,0.651428571,,17.31,N,N,,,96,NORMAL,18.81,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,12/3/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,104,97,7,35,115,2.971428571,0.904347826,2.771428571,0.843478261,,86.5,N,N,,,92,NORMAL,104,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,12/3/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,19,-2,6,32,2.833333333,0.53125,3.166666667,0.59375,Y,31,N,N,,,93,NORMAL,17,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 2,2,15,12/3/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,20,-2,9,34,2,0.529411765,2.222222222,0.588235294,,33,N,N,,,94,NORMAL,18,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,27,12/15/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4,5.2,-1.2,3.4,5.4,1.176470588,0.740740741,1.529411765,0.962962963,Y,4.1,N,N,,,142,NORMAL,4,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,27,12/15/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,17.1,13.68,3.42,3,21,5.7,0.814285714,4.56,0.651428571,,15.6,N,N,,,131,NORMAL,17.1,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,27,12/15/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,123,97,26,35,115,3.514285714,1.069565217,2.771428571,0.843478261,,105.5,N,N,,,127,HIGH,123,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,27,12/15/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,19,4,6,32,3.833333333,0.71875,3.166666667,0.59375,,25,N,N,,,128,NORMAL,23,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 4,4,27,12/15/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,20,-5,9,34,1.666666667,0.441176471,2.222222222,0.588235294,,36,N,N,,,129,NORMAL,15,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,42,12/30/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.6,5.2,-0.6,3.4,5.4,1.352941176,0.851851852,1.529411765,0.962962963,,3.5,N,N,,,170,NORMAL,4.6,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,42,12/30/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,20.52,13.68,6.84,3,21,6.84,0.977142857,4.56,0.651428571,Y,19.02,N,N,,,158,NORMAL,20.52,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,42,12/30/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,137,97,40,35,115,3.914285714,1.191304348,2.771428571,0.843478261,Y,119.5,N,N,,,154,HIGH,137,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,42,12/30/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,19,-1,6,32,3,0.5625,3.166666667,0.59375,,30,N,N,,,155,NORMAL,18,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 6,6,42,12/30/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,20,2,9,34,2.444444444,0.647058824,2.222222222,0.588235294,,29,N,N,,,156,NORMAL,22,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,1/14/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4,5.2,-1.2,3.4,5.4,1.176470588,0.740740741,1.529411765,0.962962963,,4.1,N,N,,,202,NORMAL,4,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,1/14/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,18.81,13.68,5.13,3,21,6.27,0.895714286,4.56,0.651428571,,17.31,N,N,,,188,NORMAL,18.81,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,1/14/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,131,97,34,35,115,3.742857143,1.139130435,2.771428571,0.843478261,,113.5,N,N,,,184,HIGH,131,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,1/14/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,32,3.5,0.65625,3.166666667,0.59375,,27,N,N,,,185,NORMAL,21,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 8,8,57,1/14/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,20,-6,9,34,1.555555556,0.411764706,2.222222222,0.588235294,Y,37,N,N,,,186,NORMAL,14,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,2/11/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.4,5.2,-0.8,3.4,5.4,1.294117647,0.814814815,1.529411765,0.962962963,,3.7,N,N,,,237,NORMAL,4.4,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,2/11/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,20.52,13.68,6.84,3,21,6.84,0.977142857,4.56,0.651428571,,19.02,N,N,,,224,NORMAL,20.52,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,2/11/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,131,97,34,35,115,3.742857143,1.139130435,2.771428571,0.843478261,,113.5,N,N,,,220,HIGH,131,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,2/11/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,0,6,32,3.166666667,0.59375,3.166666667,0.59375,,29,N,N,,,221,NORMAL,19,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 12,12,85,2/11/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,222,NORMAL,17,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,120,3/18/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,5.2,-0.8,3.4,5.4,1.294117647,0.814814815,1.529411765,0.962962963,,3.7,N,N,,,272,NORMAL,4.4,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,120,3/18/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,18.81,13.68,5.13,3,21,6.27,0.895714286,4.56,0.651428571,,17.31,N,N,,,260,NORMAL,18.81,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,120,3/18/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,104,97,7,35,115,2.971428571,0.904347826,2.771428571,0.843478261,,86.5,N,N,,,255,NORMAL,104,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,120,3/18/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,19,0,6,32,3.166666667,0.59375,3.166666667,0.59375,,29,N,N,,,256,NORMAL,19,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 16,16,120,3/18/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,9,34,2.111111111,0.558823529,2.222222222,0.588235294,,32,N,N,,,258,NORMAL,19,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,147,4/14/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.1,5.2,-1.1,3.4,5.4,1.205882353,0.759259259,1.529411765,0.962962963,,4,N,N,,,303,NORMAL,4.1,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,147,4/14/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,20.52,13.68,6.84,3,21,6.84,0.977142857,4.56,0.651428571,,19.02,N,N,,,291,NORMAL,20.52,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,147,4/14/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,113,97,16,35,115,3.228571429,0.982608696,2.771428571,0.843478261,,95.5,N,N,,,287,NORMAL,113,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,147,4/14/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,19,3,6,32,3.666666667,0.6875,3.166666667,0.59375,,26,N,N,,,288,NORMAL,22,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 20,20,147,4/14/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,289,NORMAL,17,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,176,5/13/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.8,5.2,-0.4,3.4,5.4,1.411764706,0.888888889,1.529411765,0.962962963,,3.3,N,N,,Y,334,NORMAL,4.8,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,176,5/13/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.8,5.2,-0.4,3.4,5.4,1.411764706,0.888888889,1.529411765,0.962962963,,3.3,N,N,,Y,334,NORMAL,4.8,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,176,5/13/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,20.52,13.68,6.84,3,21,6.84,0.977142857,4.56,0.651428571,,19.02,N,N,,Y,321,NORMAL,20.52,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,176,5/13/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,20.52,13.68,6.84,3,21,6.84,0.977142857,4.56,0.651428571,,19.02,N,N,,Y,321,NORMAL,20.52,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,176,5/13/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,112,97,15,35,115,3.2,0.973913043,2.771428571,0.843478261,,94.5,N,N,,Y,317,NORMAL,112,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,176,5/13/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,112,97,15,35,115,3.2,0.973913043,2.771428571,0.843478261,,94.5,N,N,,Y,317,NORMAL,112,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,176,5/13/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,32,3.5,0.65625,3.166666667,0.59375,,27,N,N,,Y,318,NORMAL,21,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,176,5/13/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,32,3.5,0.65625,3.166666667,0.59375,,27,N,N,,Y,318,NORMAL,21,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 24,24,176,5/13/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,9,34,2.111111111,0.558823529,2.222222222,0.588235294,,32,N,N,,Y,319,NORMAL,19,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y,End of Treatment,99,176,5/13/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,20,-1,9,34,2.111111111,0.558823529,2.222222222,0.588235294,,32,N,N,,Y,319,NORMAL,19,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,190,5/27/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.4,5.2,-0.8,3.4,5.4,1.294117647,0.814814815,1.529411765,0.962962963,,3.7,N,N,,,368,NORMAL,4.4,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,190,5/27/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,20.52,13.68,6.84,3,21,6.84,0.977142857,4.56,0.651428571,,19.02,N,N,,,356,NORMAL,20.52,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,190,5/27/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,105,97,8,35,115,3,0.913043478,2.771428571,0.843478261,,87.5,N,N,,,352,NORMAL,105,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,190,5/27/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,19,2,6,32,3.5,0.65625,3.166666667,0.59375,,27,N,N,,,353,NORMAL,21,0,No
CDISCPILOT01,1218,01-704-1218,Xanomeline Low Dose,54,Xanomeline Low Dose,54,11/19/12,5/27/13,81,>80,3,WHITE,1,F,Y,,Y, Week 26,26,190,5/27/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,9,34,1.888888889,0.5,2.222222222,0.588235294,,34,N,N,,,354,NORMAL,17,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-14,3/7/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-14,3/7/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-14,3/7/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,Y,,2,NORMAL,61,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-14,3/7/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,Y,,3,NORMAL,13,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Baseline,0,-14,3/7/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,17,,9,34,1.888888889,0.5,1.888888889,0.5,,34,N,N,Y,,4,NORMAL,17,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/4/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4,0.2,3.4,5.4,1.235294118,0.777777778,1.176470588,0.740740741,,3.9,N,N,,,56,NORMAL,4.2,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/4/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/4/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,61,-1,35,115,1.714285714,0.52173913,1.742857143,0.530434783,,112.5,N,N,,,39,NORMAL,60,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/4/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,13,1,6,32,2.333333333,0.4375,2.166666667,0.40625,,34,N,N,,,40,NORMAL,14,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 2,2,15,4/4/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,17,1,9,34,2,0.529411765,1.888888889,0.5,,33,N,N,,,41,NORMAL,18,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 4,4,27,4/16/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,89,NORMAL,4.1,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 4,4,27,4/16/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,78,NORMAL,10.26,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 4,4,27,4/16/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,61,0,35,115,1.742857143,0.530434783,1.742857143,0.530434783,,111.5,N,N,,,74,NORMAL,61,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 4,4,27,4/16/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,13,3,6,32,2.666666667,0.5,2.166666667,0.40625,,32,N,N,,,75,NORMAL,16,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 4,4,27,4/16/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,17,3,9,34,2.222222222,0.588235294,1.888888889,0.5,,31,N,N,,,76,NORMAL,20,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,5/1/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,117,NORMAL,4.1,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,5/1/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,,105,NORMAL,6.84,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,5/1/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,52,61,-9,35,115,1.485714286,0.452173913,1.742857143,0.530434783,Y,120.5,N,N,,,101,NORMAL,52,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,5/1/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,0,6,32,2.166666667,0.40625,2.166666667,0.40625,,35,N,N,,,102,NORMAL,13,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 6,6,42,5/1/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,17,5,9,34,2.444444444,0.647058824,1.888888889,0.5,,29,N,N,,,103,NORMAL,22,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 8,8,57,5/16/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.8,4,-0.2,3.4,5.4,1.117647059,0.703703704,1.176470588,0.740740741,Y,4.3,N,N,,,147,NORMAL,3.8,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 8,8,57,5/16/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,135,NORMAL,8.55,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 8,8,57,5/16/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,61,-6,35,115,1.571428571,0.47826087,1.742857143,0.530434783,,117.5,N,N,,,131,NORMAL,55,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 8,8,57,5/16/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,10,13,-3,6,32,1.666666667,0.3125,2.166666667,0.40625,,38,N,N,,,132,NORMAL,10,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 8,8,57,5/16/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,17,2,9,34,2.111111111,0.558823529,1.888888889,0.5,,32,N,N,,,133,NORMAL,19,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 12,12,85,6/13/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.1,4,0.1,3.4,5.4,1.205882353,0.759259259,1.176470588,0.740740741,,4,N,N,,,178,NORMAL,4.1,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 12,12,85,6/13/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,10.26,6.84,3.42,3,21,3.42,0.488571429,2.28,0.325714286,,21.24,N,N,,,165,NORMAL,10.26,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 12,12,85,6/13/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,61,-5,35,115,1.6,0.486956522,1.742857143,0.530434783,,116.5,N,N,,,161,NORMAL,56,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 12,12,85,6/13/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,9,13,-4,6,32,1.5,0.28125,2.166666667,0.40625,Y,39,N,N,,,162,NORMAL,9,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 12,12,85,6/13/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,17,-2,9,34,1.666666667,0.441176471,1.888888889,0.5,Y,36,N,N,,,163,NORMAL,15,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,7/11/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,Y,213,NORMAL,4,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,113,7/11/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4,4,0,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,,Y,213,NORMAL,4,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,7/11/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,201,NORMAL,8.55,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,113,7/11/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,201,NORMAL,8.55,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,7/11/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,61,-4,35,115,1.628571429,0.495652174,1.742857143,0.530434783,,115.5,N,N,,Y,196,NORMAL,57,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,113,7/11/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,61,-4,35,115,1.628571429,0.495652174,1.742857143,0.530434783,,115.5,N,N,,Y,196,NORMAL,57,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,7/11/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,13,2,6,32,2.5,0.46875,2.166666667,0.40625,,33,N,N,,Y,197,NORMAL,15,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,113,7/11/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,13,2,6,32,2.5,0.46875,2.166666667,0.40625,,33,N,N,,Y,197,NORMAL,15,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y, Week 16,16,113,7/11/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,17,2,9,34,2.111111111,0.558823529,1.888888889,0.5,,32,N,N,,Y,199,NORMAL,19,0,No
CDISCPILOT01,1233,01-704-1233,Placebo,0,Placebo,0,3/21/13,7/14/13,87,>80,3,WHITE,1,F,N,,Y,End of Treatment,99,113,7/11/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,17,2,9,34,2.111111111,0.558823529,1.888888889,0.5,,32,N,N,,Y,199,NORMAL,19,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-11,8/14/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.5,4.5,,3.4,5.4,1.323529412,0.833333333,1.323529412,0.833333333,,3.6,N,N,Y,,19,NORMAL,4.5,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-11,8/14/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-11,8/14/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,76,,35,115,2.171428571,0.660869565,2.171428571,0.660869565,,96.5,N,N,Y,,2,NORMAL,76,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-11,8/14/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,,6,35,2.5,0.428571429,2.5,0.428571429,,37.5,N,N,Y,,3,NORMAL,15,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-11,8/14/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,11,36,1.818181818,0.555555556,1.818181818,0.555555556,,34,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,12,9/5/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.5,0.1,3.4,5.4,1.352941176,0.851851852,1.323529412,0.833333333,,3.5,N,N,,,57,NORMAL,4.6,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,12,9/5/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,44,NORMAL,10.26,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,12,9/5/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,76,-1,35,115,2.142857143,0.652173913,2.171428571,0.660869565,,97.5,N,N,,,39,NORMAL,75,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,12,9/5/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,15,3,6,35,3,0.514285714,2.5,0.428571429,,34.5,N,N,,,40,NORMAL,18,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,12,9/5/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,20,2,11,36,2,0.611111111,1.818181818,0.555555556,,32,N,N,,,42,NORMAL,22,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,26,9/19/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.5,-0.4,3.4,5.4,1.205882353,0.759259259,1.323529412,0.833333333,,4,N,N,,,87,NORMAL,4.1,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,26,9/19/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,Y,22.95,N,N,,,78,NORMAL,8.55,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,26,9/19/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,76,-1,35,115,2.142857143,0.652173913,2.171428571,0.660869565,,97.5,N,N,,,75,NORMAL,75,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,26,9/19/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,18,15,3,6,35,3,0.514285714,2.5,0.428571429,,34.5,N,N,,,76,NORMAL,18,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,26,9/19/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,20,3,11,36,2.090909091,0.638888889,1.818181818,0.555555556,,31,N,N,,,77,NORMAL,23,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,46,10/9/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4,4.5,-0.5,3.4,5.4,1.176470588,0.740740741,1.323529412,0.833333333,Y,4.1,N,N,,,109,NORMAL,4,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,46,10/9/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,,22.95,N,N,,,97,NORMAL,8.55,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,46,10/9/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,73,76,-3,35,115,2.085714286,0.634782609,2.171428571,0.660869565,Y,99.5,N,N,,,93,NORMAL,73,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,46,10/9/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,23,15,8,6,35,3.833333333,0.657142857,2.5,0.428571429,,29.5,N,N,,,94,NORMAL,23,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,46,10/9/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,20,12,11,36,2.909090909,0.888888889,1.818181818,0.555555556,,26.5,N,N,,,95,NORMAL,32,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,68,10/31/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,Y,140,NORMAL,4.3,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,68,10/31/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.3,4.5,-0.2,3.4,5.4,1.264705882,0.796296296,1.323529412,0.833333333,,3.8,N,N,,Y,140,NORMAL,4.3,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,68,10/31/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,Y,128,NORMAL,10.26,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,68,10/31/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,Y,128,NORMAL,10.26,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,68,10/31/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,76,3,35,115,2.257142857,0.686956522,2.171428571,0.660869565,,93.5,N,N,,Y,124,NORMAL,79,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,68,10/31/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,76,3,35,115,2.257142857,0.686956522,2.171428571,0.660869565,,93.5,N,N,,Y,124,NORMAL,79,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,68,10/31/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,15,2,6,35,2.833333333,0.485714286,2.5,0.428571429,Y,35.5,N,N,,Y,125,NORMAL,17,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,68,10/31/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,15,2,6,35,2.833333333,0.485714286,2.5,0.428571429,Y,35.5,N,N,,Y,125,NORMAL,17,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,68,10/31/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,11,36,1.545454545,0.472222222,1.818181818,0.555555556,Y,37,N,N,,Y,126,NORMAL,17,0,No
CDISCPILOT01,1241,01-704-1241,Xanomeline High Dose,81,Xanomeline High Dose,81,8/25/13,10/9/13,86,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,68,10/31/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,20,-3,11,36,1.545454545,0.472222222,1.818181818,0.555555556,Y,37,N,N,,Y,126,NORMAL,17,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-7,8/23/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-7,8/23/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,,3,21,2.28,0.325714286,2.28,0.325714286,,24.66,N,N,Y,,6,NORMAL,6.84,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-7,8/23/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,76,,35,115,2.171428571,0.660869565,2.171428571,0.660869565,,96.5,N,N,Y,,2,NORMAL,76,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-7,8/23/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,20,,6,32,3.333333333,0.625,3.333333333,0.625,,28,N,N,Y,,3,NORMAL,20,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Baseline,0,-7,8/23/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,28,,9,34,3.111111111,0.823529412,3.111111111,0.823529412,,23.5,N,N,Y,,4,NORMAL,28,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 2,2,15,9/13/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,,,56,NORMAL,4.1,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 2,2,15,9/13/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,11.97,6.84,5.13,3,21,3.99,0.57,2.28,0.325714286,,19.53,N,N,,,43,NORMAL,11.97,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 2,2,15,9/13/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,82,76,6,35,115,2.342857143,0.713043478,2.171428571,0.660869565,,90.5,N,N,,,39,NORMAL,82,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 2,2,15,9/13/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,20,-1,6,32,3.166666667,0.59375,3.333333333,0.625,,29,N,N,,,40,NORMAL,19,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 2,2,15,9/13/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,28,-4,9,34,2.666666667,0.705882353,3.111111111,0.823529412,,27,N,N,,,41,NORMAL,24,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 4,4,28,9/26/12,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,,,90,NORMAL,4.1,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 4,4,28,9/26/12,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,6.84,6.84,0,3,21,2.28,0.325714286,2.28,0.325714286,Y,24.66,N,N,,,78,NORMAL,6.84,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 4,4,28,9/26/12,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,79,76,3,35,115,2.257142857,0.686956522,2.171428571,0.660869565,,93.5,N,N,,,74,NORMAL,79,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 4,4,28,9/26/12,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,20,-3,6,32,2.833333333,0.53125,3.333333333,0.625,Y,31,N,N,,,75,NORMAL,17,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 4,4,28,9/26/12,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,28,-6,9,34,2.444444444,0.647058824,3.111111111,0.823529412,Y,29,N,N,,,76,NORMAL,22,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 6,6,43,10/11/12,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,,,120,NORMAL,4.1,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 6,6,43,10/11/12,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,,108,NORMAL,8.55,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 6,6,43,10/11/12,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,75,76,-1,35,115,2.142857143,0.652173913,2.171428571,0.660869565,Y,97.5,N,N,,,104,NORMAL,75,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 6,6,43,10/11/12,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,20,-1,6,32,3.166666667,0.59375,3.333333333,0.625,,29,N,N,,,105,NORMAL,19,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 6,6,43,10/11/12,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,26,28,-2,9,34,2.888888889,0.764705882,3.111111111,0.823529412,,25,N,N,,,106,NORMAL,26,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 8,8,56,10/24/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.8,4.1,-0.3,3.4,5.4,1.117647059,0.703703704,1.205882353,0.759259259,Y,4.3,N,N,,Y,150,NORMAL,3.8,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,56,10/24/12,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.8,4.1,-0.3,3.4,5.4,1.117647059,0.703703704,1.205882353,0.759259259,Y,4.3,N,N,,Y,150,NORMAL,3.8,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 8,8,56,10/24/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,138,NORMAL,8.55,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,56,10/24/12,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,8.55,6.84,1.71,3,21,2.85,0.407142857,2.28,0.325714286,,22.95,N,N,,Y,138,NORMAL,8.55,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 8,8,56,10/24/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,76,1,35,115,2.2,0.669565217,2.171428571,0.660869565,,95.5,N,N,,Y,134,NORMAL,77,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,56,10/24/12,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,76,1,35,115,2.2,0.669565217,2.171428571,0.660869565,,95.5,N,N,,Y,134,NORMAL,77,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 8,8,56,10/24/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,20,2,6,32,3.666666667,0.6875,3.333333333,0.625,,26,N,N,,Y,135,NORMAL,22,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,56,10/24/12,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,22,20,2,6,32,3.666666667,0.6875,3.333333333,0.625,,26,N,N,,Y,135,NORMAL,22,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y, Week 8,8,56,10/24/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,28,0,9,34,3.111111111,0.823529412,3.111111111,0.823529412,,23.5,N,N,,Y,136,NORMAL,28,0,No
CDISCPILOT01,1260,01-704-1260,Placebo,0,Placebo,0,8/30/12,11/4/12,71,65-80,2,WHITE,1,F,N,,Y,End of Treatment,99,56,10/24/12,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,28,0,9,34,3.111111111,0.823529412,3.111111111,0.823529412,,23.5,N,N,,Y,136,NORMAL,28,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-8,10/5/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.1,4.1,,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,Y,,19,NORMAL,4.1,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-8,10/5/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,Y,,6,NORMAL,11.97,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-8,10/5/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,45,45,,35,115,1.285714286,0.391304348,1.285714286,0.391304348,,127.5,N,N,Y,,2,NORMAL,45,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-8,10/5/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,12,,6,35,2,0.342857143,2,0.342857143,,40.5,N,N,Y,,3,NORMAL,12,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Baseline,0,-8,10/5/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,20,,11,36,1.818181818,0.555555556,1.818181818,0.555555556,,34,N,N,Y,,4,NORMAL,20,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/27/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.4,4.1,0.3,3.4,5.4,1.294117647,0.814814815,1.205882353,0.759259259,,3.7,N,N,,,56,NORMAL,4.4,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/27/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,8.55,11.97,-3.42,3,21,2.85,0.407142857,3.99,0.57,Y,22.95,N,N,,,43,NORMAL,8.55,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/27/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,49,45,4,35,115,1.4,0.426086957,1.285714286,0.391304348,,123.5,N,N,,,39,NORMAL,49,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/27/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,12,7,6,35,3.166666667,0.542857143,2,0.342857143,,33.5,N,N,,,40,NORMAL,19,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 2,2,15,10/27/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,20,4,11,36,2.181818182,0.666666667,1.818181818,0.555555556,,30,N,N,,,41,NORMAL,24,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,11/8/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,3.9,4.1,-0.2,3.4,5.4,1.147058824,0.722222222,1.205882353,0.759259259,Y,4.2,N,N,,,90,NORMAL,3.9,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,11/8/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,13.68,11.97,1.71,3,21,4.56,0.651428571,3.99,0.57,,17.82,N,N,,,78,NORMAL,13.68,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,11/8/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,42,45,-3,35,115,1.2,0.365217391,1.285714286,0.391304348,,130.5,N,N,,,74,NORMAL,42,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,11/8/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,12,9,6,35,3.5,0.6,2,0.342857143,,31.5,N,N,,,75,NORMAL,21,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 4,4,27,11/8/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,20,7,11,36,2.454545455,0.75,1.818181818,0.555555556,,27,N,N,,,76,NORMAL,27,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,41,11/22/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.1,0,3.4,5.4,1.205882353,0.759259259,1.205882353,0.759259259,,4,N,N,,,120,NORMAL,4.1,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,41,11/22/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,10.26,11.97,-1.71,3,21,3.42,0.488571429,3.99,0.57,,21.24,N,N,,,108,NORMAL,10.26,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,41,11/22/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,45,45,0,35,115,1.285714286,0.391304348,1.285714286,0.391304348,,127.5,N,N,,,104,NORMAL,45,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,41,11/22/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,12,2,6,35,2.333333333,0.4,2,0.342857143,Y,38.5,N,N,,,105,NORMAL,14,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 6,6,41,11/22/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,22,20,2,11,36,2,0.611111111,1.818181818,0.555555556,Y,32,N,N,,,106,NORMAL,22,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,12/6/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.9,4.1,-0.2,3.4,5.4,1.147058824,0.722222222,1.205882353,0.759259259,,4.2,N,N,,Y,151,NORMAL,3.9,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,12/6/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.9,4.1,-0.2,3.4,5.4,1.147058824,0.722222222,1.205882353,0.759259259,,4.2,N,N,,Y,151,NORMAL,3.9,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,12/6/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,Y,138,NORMAL,11.97,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,12/6/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,11.97,11.97,0,3,21,3.99,0.57,3.99,0.57,,19.53,N,N,,Y,138,NORMAL,11.97,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,12/6/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,39,45,-6,35,115,1.114285714,0.339130435,1.285714286,0.391304348,Y,133.5,N,N,,Y,134,NORMAL,39,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,12/6/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,39,45,-6,35,115,1.114285714,0.339130435,1.285714286,0.391304348,Y,133.5,N,N,,Y,134,NORMAL,39,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,12/6/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,12,7,6,35,3.166666667,0.542857143,2,0.342857143,,33.5,N,N,,Y,135,NORMAL,19,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,12/6/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,12,7,6,35,3.166666667,0.542857143,2,0.342857143,,33.5,N,N,,Y,135,NORMAL,19,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y, Week 8,8,55,12/6/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,20,4,11,36,2.181818182,0.666666667,1.818181818,0.555555556,,30,N,N,,Y,136,NORMAL,24,0,No
CDISCPILOT01,1266,01-704-1266,Xanomeline High Dose,81,Xanomeline High Dose,81,10/13/13,12/6/13,82,>80,3,WHITE,1,M,N,Y,Y,End of Treatment,99,55,12/6/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,20,4,11,36,2.181818182,0.666666667,1.818181818,0.555555556,,30,N,N,,Y,136,NORMAL,24,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-26,6/12/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,15.39,15.39,,3,21,5.13,0.732857143,5.13,0.732857143,,16.11,N,N,Y,,6,NORMAL,15.39,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-26,6/12/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,16,,6,32,2.666666667,0.5,2.666666667,0.5,,32,N,N,Y,,2,NORMAL,16,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Baseline,0,-26,6/12/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,60,60,,9,34,6.666666667,1.764705882,6.666666667,1.764705882,,55.5,H,H,Y,,4,HIGH,60,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,8/4/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,,,3.4,5.4,1.205882353,0.759259259,,,Y,4,N,,,Y,53,NORMAL,4.1,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,28,8/4/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,,,3.4,5.4,1.205882353,0.759259259,,,Y,4,N,,,Y,53,NORMAL,4.1,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,8/4/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,,15.39,,3,21,,,5.13,0.732857143,,,N,N,,Y,41,,,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,28,8/4/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,,15.39,,3,21,,,5.13,0.732857143,,,N,N,,Y,41,,,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,8/4/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,,,35,115,1.314285714,0.4,,,Y,126.5,N,,,Y,37,NORMAL,46,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,28,8/4/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,46,,,35,115,1.314285714,0.4,,,Y,126.5,N,,,Y,37,NORMAL,46,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,8/4/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,16,-3,6,32,2.166666667,0.40625,2.666666667,0.5,Y,35,N,N,,Y,38,NORMAL,13,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,28,8/4/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,16,-3,6,32,2.166666667,0.40625,2.666666667,0.5,Y,35,N,N,,Y,38,NORMAL,13,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y, Week 4,4,28,8/4/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,60,-39,9,34,2.333333333,0.617647059,6.666666667,1.764705882,Y,30,N,H,,Y,39,NORMAL,21,0,No
CDISCPILOT01,1323,01-704-1323,Xanomeline Low Dose,54,Xanomeline Low Dose,54,7/8/13,8/5/13,68,65-80,2,WHITE,1,F,N,Y,Y,End of Treatment,99,28,8/4/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,60,-39,9,34,2.333333333,0.617647059,6.666666667,1.764705882,Y,30,N,H,,Y,39,NORMAL,21,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Baseline,0,-8,4/15/14,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,19,NORMAL,4.6,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Baseline,0,-8,4/15/14,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,8.55,8.55,,3,21,2.85,0.407142857,2.85,0.407142857,,22.95,N,N,Y,,6,NORMAL,8.55,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Baseline,0,-8,4/15/14,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,96,96,,35,115,2.742857143,0.834782609,2.742857143,0.834782609,,78.5,N,N,Y,,2,NORMAL,96,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Baseline,0,-8,4/15/14,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,17,,6,35,2.833333333,0.485714286,2.833333333,0.485714286,,35.5,N,N,Y,,3,NORMAL,17,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Baseline,0,-8,4/15/14,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,Y,,4,NORMAL,21,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 2,2,15,5/7/14,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,Y,3.9,N,N,,,57,NORMAL,4.2,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 2,2,15,5/7/14,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,20.52,8.55,11.97,3,21,6.84,0.977142857,2.85,0.407142857,Y,19.02,N,N,,,44,NORMAL,20.52,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 2,2,15,5/7/14,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,88,96,-8,35,115,2.514285714,0.765217391,2.742857143,0.834782609,,84.5,N,N,,,39,NORMAL,88,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 2,2,15,5/7/14,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,35,2,0.342857143,2.833333333,0.485714286,Y,40.5,N,N,,,40,NORMAL,12,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 2,2,15,5/7/14,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,21,0,11,36,1.909090909,0.583333333,1.909090909,0.583333333,,33,N,N,,,42,NORMAL,21,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 4,4,27,5/19/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,,3.8,N,N,,,93,NORMAL,4.3,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 4,4,27,5/19/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,18.81,8.55,10.26,3,21,6.27,0.895714286,2.85,0.407142857,,17.31,N,N,,,81,NORMAL,18.81,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 4,4,27,5/19/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,96,-10,35,115,2.457142857,0.747826087,2.742857143,0.834782609,,86.5,N,N,,,76,NORMAL,86,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 4,4,27,5/19/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,17,-2,6,35,2.5,0.428571429,2.833333333,0.485714286,,37.5,N,N,,,77,NORMAL,15,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 4,4,27,5/19/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,19,21,-2,11,36,1.727272727,0.527777778,1.909090909,0.583333333,,35,N,N,,,79,NORMAL,19,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 6,6,43,6/4/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,123,NORMAL,4.4,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 6,6,43,6/4/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,18.81,8.55,10.26,3,21,6.27,0.895714286,2.85,0.407142857,,17.31,N,N,,,112,NORMAL,18.81,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 6,6,43,6/4/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,84,96,-12,35,115,2.4,0.730434783,2.742857143,0.834782609,,88.5,N,N,,,107,NORMAL,84,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 6,6,43,6/4/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,17,-3,6,35,2.333333333,0.4,2.833333333,0.485714286,,38.5,N,N,,,108,NORMAL,14,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 6,6,43,6/4/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,21,3,11,36,2.181818182,0.666666667,1.909090909,0.583333333,,30,N,N,,,110,NORMAL,24,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 8,8,57,6/18/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.2,4.6,-0.4,3.4,5.4,1.235294118,0.777777778,1.352941176,0.851851852,,3.9,N,N,,,152,NORMAL,4.2,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 8,8,57,6/18/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,18.81,8.55,10.26,3,21,6.27,0.895714286,2.85,0.407142857,,17.31,N,N,,,140,NORMAL,18.81,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 8,8,57,6/18/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,81,96,-15,35,115,2.314285714,0.704347826,2.742857143,0.834782609,Y,91.5,N,N,,,136,NORMAL,81,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 8,8,57,6/18/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,35,2,0.342857143,2.833333333,0.485714286,,40.5,N,N,,,137,NORMAL,12,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 8,8,57,6/18/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,21,-1,11,36,1.818181818,0.555555556,1.909090909,0.583333333,,34,N,N,,,138,NORMAL,20,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 16,16,106,8/6/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,Y,183,NORMAL,4.4,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,106,8/6/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,Y,183,NORMAL,4.4,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 16,16,106,8/6/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,13.68,8.55,5.13,3,21,4.56,0.651428571,2.85,0.407142857,,17.82,N,N,,Y,170,NORMAL,13.68,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,106,8/6/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,13.68,8.55,5.13,3,21,4.56,0.651428571,2.85,0.407142857,,17.82,N,N,,Y,170,NORMAL,13.68,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 16,16,106,8/6/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,96,-1,35,115,2.714285714,0.826086957,2.742857143,0.834782609,,77.5,N,N,,Y,166,NORMAL,95,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,106,8/6/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,95,96,-1,35,115,2.714285714,0.826086957,2.742857143,0.834782609,,77.5,N,N,,Y,166,NORMAL,95,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 16,16,106,8/6/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,35,2,0.342857143,2.833333333,0.485714286,,40.5,N,N,,Y,167,NORMAL,12,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,106,8/6/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,17,-5,6,35,2,0.342857143,2.833333333,0.485714286,,40.5,N,N,,Y,167,NORMAL,12,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y, Week 16,16,106,8/6/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,21,-4,11,36,1.545454545,0.472222222,1.909090909,0.583333333,Y,37,N,N,,Y,168,NORMAL,17,0,No
CDISCPILOT01,1325,01-704-1325,Xanomeline Low Dose,54,Xanomeline Low Dose,54,4/23/14,7/4/14,81,>80,3,WHITE,1,M,N,,Y,End of Treatment,99,106,8/6/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,21,-4,11,36,1.545454545,0.472222222,1.909090909,0.583333333,Y,37,N,N,,Y,168,NORMAL,17,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-15,11/24/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.9,4.9,,3.4,5.4,1.441176471,0.907407407,1.441176471,0.907407407,,3.2,N,N,Y,,19,NORMAL,4.9,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-15,11/24/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,17.1,17.1,,3,21,5.7,0.814285714,5.7,0.814285714,,15.6,N,N,Y,,6,NORMAL,17.1,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-15,11/24/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,47,47,,35,115,1.342857143,0.408695652,1.342857143,0.408695652,,125.5,N,N,Y,,2,NORMAL,47,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-15,11/24/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,15,,6,35,2.5,0.428571429,2.5,0.428571429,,37.5,N,N,Y,,3,NORMAL,15,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Baseline,0,-15,11/24/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,36,36,,11,36,3.272727273,1,3.272727273,1,,30.5,N,N,Y,,4,NORMAL,36,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,12/23/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.6,4.9,-0.3,3.4,5.4,1.352941176,0.851851852,1.441176471,0.907407407,,3.5,N,N,,,56,NORMAL,4.6,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,12/23/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,25.65,17.1,8.55,3,21,8.55,1.221428571,5.7,0.814285714,,24.15,N,N,,,43,HIGH,25.65,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,12/23/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,47,12,35,115,1.685714286,0.513043478,1.342857143,0.408695652,,113.5,N,N,,,39,NORMAL,59,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,12/23/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,16,15,1,6,35,2.666666667,0.457142857,2.5,0.428571429,,36.5,N,N,,,40,NORMAL,16,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 2,2,15,12/23/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,16,36,-20,11,36,1.454545455,0.444444444,3.272727273,1,,38,N,N,,,41,NORMAL,16,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,1/4/14,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.9,-0.8,3.4,5.4,1.205882353,0.759259259,1.441176471,0.907407407,Y,4,N,N,,,90,NORMAL,4.1,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,1/4/14,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,25.65,17.1,8.55,3,21,8.55,1.221428571,5.7,0.814285714,,24.15,N,N,,,78,HIGH,25.65,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,1/4/14,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,47,4,35,115,1.457142857,0.443478261,1.342857143,0.408695652,Y,121.5,N,N,,,74,NORMAL,51,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,1/4/14,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,15,-3,6,35,2,0.342857143,2.5,0.428571429,,40.5,N,N,,,75,NORMAL,12,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 4,4,27,1/4/14,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,14,36,-22,11,36,1.272727273,0.388888889,3.272727273,1,Y,40,N,N,,,76,NORMAL,14,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,43,1/20/14,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.1,4.9,-0.8,3.4,5.4,1.205882353,0.759259259,1.441176471,0.907407407,,4,N,N,,,120,NORMAL,4.1,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,43,1/20/14,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,20.52,17.1,3.42,3,21,6.84,0.977142857,5.7,0.814285714,,19.02,N,N,,,108,NORMAL,20.52,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,43,1/20/14,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,53,47,6,35,115,1.514285714,0.460869565,1.342857143,0.408695652,,119.5,N,N,,,104,NORMAL,53,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,43,1/20/14,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,11,15,-4,6,35,1.833333333,0.314285714,2.5,0.428571429,Y,41.5,N,N,,,105,NORMAL,11,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 6,6,43,1/20/14,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,15,36,-21,11,36,1.363636364,0.416666667,3.272727273,1,,39,N,N,,,106,NORMAL,15,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,57,2/3/14,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.1,4.9,-0.8,3.4,5.4,1.205882353,0.759259259,1.441176471,0.907407407,,4,N,N,,,150,NORMAL,4.1,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,57,2/3/14,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,18.81,17.1,1.71,3,21,6.27,0.895714286,5.7,0.814285714,,17.31,N,N,,,138,NORMAL,18.81,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,57,2/3/14,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,56,47,9,35,115,1.6,0.486956522,1.342857143,0.408695652,,116.5,N,N,,,134,NORMAL,56,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,57,2/3/14,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,12,15,-3,6,35,2,0.342857143,2.5,0.428571429,,40.5,N,N,,,135,NORMAL,12,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 8,8,57,2/3/14,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,36,-19,11,36,1.545454545,0.472222222,3.272727273,1,,37,N,N,,,136,NORMAL,17,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,70,2/16/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.6,4.9,-0.3,3.4,5.4,1.352941176,0.851851852,1.441176471,0.907407407,,3.5,N,N,,Y,181,NORMAL,4.6,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,70,2/16/14,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.6,4.9,-0.3,3.4,5.4,1.352941176,0.851851852,1.441176471,0.907407407,,3.5,N,N,,Y,181,NORMAL,4.6,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,70,2/16/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,29.07,17.1,11.97,3,21,9.69,1.384285714,5.7,0.814285714,Y,27.57,N,N,,Y,168,HIGH,29.07,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,70,2/16/14,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,29.07,17.1,11.97,3,21,9.69,1.384285714,5.7,0.814285714,Y,27.57,N,N,,Y,168,HIGH,29.07,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,70,2/16/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,47,4,35,115,1.457142857,0.443478261,1.342857143,0.408695652,,121.5,N,N,,Y,164,NORMAL,51,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,70,2/16/14,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,51,47,4,35,115,1.457142857,0.443478261,1.342857143,0.408695652,,121.5,N,N,,Y,164,NORMAL,51,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,70,2/16/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,35,2.166666667,0.371428571,2.5,0.428571429,,39.5,N,N,,Y,165,NORMAL,13,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,70,2/16/14,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,15,-2,6,35,2.166666667,0.371428571,2.5,0.428571429,,39.5,N,N,,Y,165,NORMAL,13,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y, Week 12,12,70,2/16/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,36,-19,11,36,1.545454545,0.472222222,3.272727273,1,,37,N,N,,Y,166,NORMAL,17,0,No
CDISCPILOT01,1332,01-704-1332,Xanomeline High Dose,81,Xanomeline High Dose,81,12/9/13,2/14/14,80,65-80,2,WHITE,1,M,N,Y,Y,End of Treatment,99,70,2/16/14,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,17,36,-19,11,36,1.545454545,0.472222222,3.272727273,1,,37,N,N,,Y,166,NORMAL,17,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/26/13,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.6,4.6,,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,Y,,20,NORMAL,4.6,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/26/13,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,15.39,15.39,,3,21,5.13,0.732857143,5.13,0.732857143,,16.11,N,N,Y,,7,NORMAL,15.39,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/26/13,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,74,74,,35,115,2.114285714,0.643478261,2.114285714,0.643478261,,98.5,N,N,Y,,2,NORMAL,74,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/26/13,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,14,,6,35,2.333333333,0.4,2.333333333,0.4,,38.5,N,N,Y,,3,NORMAL,14,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Baseline,0,-16,9/26/13,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,18,,11,36,1.636363636,0.5,1.636363636,0.5,,36,N,N,Y,,5,NORMAL,18,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,10/26/13,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.8,4.6,0.2,3.4,5.4,1.411764706,0.888888889,1.352941176,0.851851852,,3.3,N,N,,,70,NORMAL,4.8,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,10/26/13,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,15.39,-5.13,3,21,3.42,0.488571429,5.13,0.732857143,Y,21.24,N,N,,,58,NORMAL,10.26,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,10/26/13,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,74,-8,35,115,1.885714286,0.573913043,2.114285714,0.643478261,,106.5,N,N,,,54,NORMAL,66,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,10/26/13,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,14,5,6,35,3.166666667,0.542857143,2.333333333,0.4,,33.5,N,N,,,55,NORMAL,19,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 2,2,15,10/26/13,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,18,6,11,36,2.181818182,0.666666667,1.636363636,0.5,,30,N,N,,,56,NORMAL,24,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,11/7/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,Y,3.8,N,N,,,90,NORMAL,4.3,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 4,4,27,11/7/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,63,74,-11,35,115,1.8,0.547826087,2.114285714,0.643478261,,109.5,N,N,,,83,NORMAL,63,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,36,11/16/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.6,-0.2,3.4,5.4,1.294117647,0.814814815,1.352941176,0.851851852,,3.7,N,N,,,112,NORMAL,4.4,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,36,11/16/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,13.68,15.39,-1.71,3,21,4.56,0.651428571,5.13,0.732857143,,17.82,N,N,,,100,NORMAL,13.68,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,36,11/16/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,59,74,-15,35,115,1.685714286,0.513043478,2.114285714,0.643478261,Y,113.5,N,N,,,96,NORMAL,59,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,36,11/16/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,14,7,6,35,3.5,0.6,2.333333333,0.4,,31.5,N,N,,,97,NORMAL,21,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 6,6,36,11/16/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,18,5,11,36,2.090909091,0.638888889,1.636363636,0.5,,31,N,N,,,98,NORMAL,23,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,52,12/2/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,4.6,4.6,0,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,,,142,NORMAL,4.6,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,52,12/2/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,10.26,15.39,-5.13,3,21,3.42,0.488571429,5.13,0.732857143,,21.24,N,N,,,130,NORMAL,10.26,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,52,12/2/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,74,-7,35,115,1.914285714,0.582608696,2.114285714,0.643478261,,105.5,N,N,,,126,NORMAL,67,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,52,12/2/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,14,0,6,35,2.333333333,0.4,2.333333333,0.4,Y,38.5,N,N,,,127,NORMAL,14,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 8,8,52,12/2/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,11,36,1.818181818,0.555555556,1.636363636,0.5,,34,N,N,,,128,NORMAL,20,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,78,12/28/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,4.6,4.6,0,3.4,5.4,1.352941176,0.851851852,1.352941176,0.851851852,,3.5,N,N,,,169,NORMAL,4.6,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,78,12/28/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,15.39,15.39,0,3,21,5.13,0.732857143,5.13,0.732857143,,16.11,N,N,,,159,NORMAL,15.39,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,78,12/28/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,74,-7,35,115,1.914285714,0.582608696,2.114285714,0.643478261,,105.5,N,N,,,156,NORMAL,67,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,78,12/28/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,14,5,6,35,3.166666667,0.542857143,2.333333333,0.4,,33.5,N,N,,,157,NORMAL,19,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 12,12,78,12/28/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,18,5,11,36,2.090909091,0.638888889,1.636363636,0.5,,31,N,N,,,158,NORMAL,23,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,107,1/26/14,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.5,4.6,-0.1,3.4,5.4,1.323529412,0.833333333,1.352941176,0.851851852,,3.6,N,N,,,195,NORMAL,4.5,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,107,1/26/14,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,13.68,15.39,-1.71,3,21,4.56,0.651428571,5.13,0.732857143,,17.82,N,N,,,183,NORMAL,13.68,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,107,1/26/14,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,74,-14,35,115,1.714285714,0.52173913,2.114285714,0.643478261,,112.5,N,N,,,179,NORMAL,60,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,107,1/26/14,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,14,1,6,35,2.5,0.428571429,2.333333333,0.4,,37.5,N,N,,,180,NORMAL,15,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 16,16,107,1/26/14,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,20,18,2,11,36,1.818181818,0.555555556,1.636363636,0.5,,34,N,N,,,181,NORMAL,20,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/1/14,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,5.1,4.6,0.5,3.4,5.4,1.5,0.944444444,1.352941176,0.851851852,,3.4,N,N,,,225,NORMAL,5.1,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/1/14,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,13.68,15.39,-1.71,3,21,4.56,0.651428571,5.13,0.732857143,,17.82,N,N,,,214,NORMAL,13.68,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/1/14,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,61,74,-13,35,115,1.742857143,0.530434783,2.114285714,0.643478261,,111.5,N,N,,,210,NORMAL,61,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/1/14,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,14,14,0,6,35,2.333333333,0.4,2.333333333,0.4,,38.5,N,N,,,211,NORMAL,14,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 20,20,141,3/1/14,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,18,18,0,11,36,1.636363636,0.5,1.636363636,0.5,Y,36,N,N,,,212,NORMAL,18,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,175,4/4/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,,3.8,N,N,,Y,254,NORMAL,4.3,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,175,4/4/14,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,4.3,4.6,-0.3,3.4,5.4,1.264705882,0.796296296,1.352941176,0.851851852,,3.8,N,N,,Y,254,NORMAL,4.3,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,175,4/4/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,13.68,15.39,-1.71,3,21,4.56,0.651428571,5.13,0.732857143,,17.82,N,N,,Y,241,NORMAL,13.68,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,175,4/4/14,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,13.68,15.39,-1.71,3,21,4.56,0.651428571,5.13,0.732857143,,17.82,N,N,,Y,241,NORMAL,13.68,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,175,4/4/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,74,-5,35,115,1.971428571,0.6,2.114285714,0.643478261,,103.5,N,N,,Y,237,NORMAL,69,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,175,4/4/14,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,69,74,-5,35,115,1.971428571,0.6,2.114285714,0.643478261,,103.5,N,N,,Y,237,NORMAL,69,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,175,4/4/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,14,3,6,35,2.833333333,0.485714286,2.333333333,0.4,,35.5,N,N,,Y,238,NORMAL,17,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,175,4/4/14,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,17,14,3,6,35,2.833333333,0.485714286,2.333333333,0.4,,35.5,N,N,,Y,238,NORMAL,17,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 24,24,175,4/4/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,18,6,11,36,2.181818182,0.666666667,1.636363636,0.5,,30,N,N,,Y,239,NORMAL,24,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y,End of Treatment,99,175,4/4/14,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,24,18,6,11,36,2.181818182,0.666666667,1.636363636,0.5,,30,N,N,,Y,239,NORMAL,24,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,189,4/18/14,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4.1,4.6,-0.5,3.4,5.4,1.205882353,0.759259259,1.352941176,0.851851852,,4,N,N,,,288,NORMAL,4.1,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,189,4/18/14,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,11.97,15.39,-3.42,3,21,3.99,0.57,5.13,0.732857143,,19.53,N,N,,,276,NORMAL,11.97,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,189,4/18/14,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,74,-6,35,115,1.942857143,0.591304348,2.114285714,0.643478261,,104.5,N,N,,,272,NORMAL,68,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,189,4/18/14,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,21,14,7,6,35,3.5,0.6,2.333333333,0.4,,31.5,N,N,,,273,NORMAL,21,0,No
CDISCPILOT01,1351,01-704-1351,Placebo,0,Placebo,0,10/12/13,4/18/14,70,65-80,2,WHITE,1,M,Y,,Y, Week 26,26,189,4/18/14,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,21,18,3,11,36,1.909090909,0.583333333,1.636363636,0.5,,33,N,N,,,274,NORMAL,21,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-9,11/28/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4.3,4.3,,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,Y,,19,NORMAL,4.3,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-9,11/28/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,Y,,6,NORMAL,13.68,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-9,11/28/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,80,80,,35,115,2.285714286,0.695652174,2.285714286,0.695652174,,92.5,N,N,Y,,2,NORMAL,80,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-9,11/28/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,36,36,,6,35,6,1.028571429,6,1.028571429,,33,N,N,Y,,3,HIGH,36,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Baseline,0,-9,11/28/12,SCREENING 1,1,Aspartate Aminotransferase (U/L),AST,25,CHEM,38,38,,11,36,3.454545455,1.055555556,3.454545455,1.055555556,,32.5,N,N,Y,,4,HIGH,38,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,12/21/12,WEEK 2,4,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,56,NORMAL,4.3,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,12/21/12,WEEK 2,4,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,Y,21.24,N,N,,,43,NORMAL,10.26,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,12/21/12,WEEK 2,4,Alkaline Phosphatase (U/L),ALP,22,CHEM,77,80,-3,35,115,2.2,0.669565217,2.285714286,0.695652174,,95.5,N,N,,,39,NORMAL,77,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,12/21/12,WEEK 2,4,Alanine Aminotransferase (U/L),ALT,24,CHEM,26,36,-10,6,35,4.333333333,0.742857143,6,1.028571429,,26.5,N,N,,,40,NORMAL,26,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 2,2,15,12/21/12,WEEK 2,4,Aspartate Aminotransferase (U/L),AST,25,CHEM,29,38,-9,11,36,2.636363636,0.805555556,3.454545455,1.055555556,,25,N,N,,,41,NORMAL,29,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 4,4,27,1/2/13,WEEK 4,5,Potassium (mmol/L),K,19,CHEM,4.1,4.3,-0.2,3.4,5.4,1.205882353,0.759259259,1.264705882,0.796296296,,4,N,N,,,92,NORMAL,4.1,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 4,4,27,1/2/13,WEEK 4,5,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,80,NORMAL,10.26,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 4,4,27,1/2/13,WEEK 4,5,Alkaline Phosphatase (U/L),ALP,22,CHEM,76,80,-4,35,115,2.171428571,0.660869565,2.285714286,0.695652174,,96.5,N,N,,,75,NORMAL,76,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 4,4,27,1/2/13,WEEK 4,5,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,36,-11,6,35,4.166666667,0.714285714,6,1.028571429,,27.5,N,N,,,76,NORMAL,25,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 4,4,27,1/2/13,WEEK 4,5,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,38,-10,11,36,2.545454545,0.777777778,3.454545455,1.055555556,,26,N,N,,,78,NORMAL,28,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,1/18/13,WEEK 6,7,Potassium (mmol/L),K,19,CHEM,4.4,4.3,0.1,3.4,5.4,1.294117647,0.814814815,1.264705882,0.796296296,,3.7,N,N,,,122,NORMAL,4.4,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,1/18/13,WEEK 6,7,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,110,NORMAL,13.68,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,1/18/13,WEEK 6,7,Alkaline Phosphatase (U/L),ALP,22,CHEM,68,80,-12,35,115,1.942857143,0.591304348,2.285714286,0.695652174,,104.5,N,N,,,106,NORMAL,68,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,1/18/13,WEEK 6,7,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,36,-11,6,35,4.166666667,0.714285714,6,1.028571429,,27.5,N,N,,,107,NORMAL,25,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 6,6,43,1/18/13,WEEK 6,7,Aspartate Aminotransferase (U/L),AST,25,CHEM,31,38,-7,11,36,2.818181818,0.861111111,3.454545455,1.055555556,,25.5,N,N,,,108,NORMAL,31,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 8,8,55,1/30/13,WEEK 8,8,Potassium (mmol/L),K,19,CHEM,3.7,4.3,-0.6,3.4,5.4,1.088235294,0.685185185,1.264705882,0.796296296,Y,4.4,N,N,,,153,NORMAL,3.7,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 8,8,55,1/30/13,WEEK 8,8,Bilirubin (umol/L),BILI,21,CHEM,15.39,13.68,1.71,3,21,5.13,0.732857143,4.56,0.651428571,,16.11,N,N,,,141,NORMAL,15.39,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 8,8,55,1/30/13,WEEK 8,8,Alkaline Phosphatase (U/L),ALP,22,CHEM,82,80,2,35,115,2.342857143,0.713043478,2.285714286,0.695652174,,90.5,N,N,,,136,NORMAL,82,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 8,8,55,1/30/13,WEEK 8,8,Alanine Aminotransferase (U/L),ALT,24,CHEM,19,36,-17,6,35,3.166666667,0.542857143,6,1.028571429,,33.5,N,N,,,137,NORMAL,19,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 8,8,55,1/30/13,WEEK 8,8,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,38,-6,11,36,2.909090909,0.888888889,3.454545455,1.055555556,,26.5,N,N,,,139,NORMAL,32,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 12,12,83,2/27/13,WEEK 12,9,Potassium (mmol/L),K,19,CHEM,3.9,4.3,-0.4,3.4,5.4,1.147058824,0.722222222,1.264705882,0.796296296,,4.2,N,N,,,186,NORMAL,3.9,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 12,12,83,2/27/13,WEEK 12,9,Bilirubin (umol/L),BILI,21,CHEM,11.97,13.68,-1.71,3,21,3.99,0.57,4.56,0.651428571,,19.53,N,N,,,173,NORMAL,11.97,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 12,12,83,2/27/13,WEEK 12,9,Alkaline Phosphatase (U/L),ALP,22,CHEM,66,80,-14,35,115,1.885714286,0.573913043,2.285714286,0.695652174,,106.5,N,N,,,168,NORMAL,66,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 12,12,83,2/27/13,WEEK 12,9,Alanine Aminotransferase (U/L),ALT,24,CHEM,15,36,-21,6,35,2.5,0.428571429,6,1.028571429,Y,37.5,N,N,,,169,NORMAL,15,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 12,12,83,2/27/13,WEEK 12,9,Aspartate Aminotransferase (U/L),AST,25,CHEM,23,38,-15,11,36,2.090909091,0.638888889,3.454545455,1.055555556,Y,31,N,N,,,171,NORMAL,23,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 16,16,111,3/27/13,WEEK 16,10,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,220,NORMAL,4.3,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 16,16,111,3/27/13,WEEK 16,10,Bilirubin (umol/L),BILI,21,CHEM,10.26,13.68,-3.42,3,21,3.42,0.488571429,4.56,0.651428571,,21.24,N,N,,,208,NORMAL,10.26,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 16,16,111,3/27/13,WEEK 16,10,Alkaline Phosphatase (U/L),ALP,22,CHEM,67,80,-13,35,115,1.914285714,0.582608696,2.285714286,0.695652174,,105.5,N,N,,,204,NORMAL,67,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 16,16,111,3/27/13,WEEK 16,10,Alanine Aminotransferase (U/L),ALT,24,CHEM,20,36,-16,6,35,3.333333333,0.571428571,6,1.028571429,,32.5,N,N,,,205,NORMAL,20,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 16,16,111,3/27/13,WEEK 16,10,Aspartate Aminotransferase (U/L),AST,25,CHEM,27,38,-11,11,36,2.454545455,0.75,3.454545455,1.055555556,,27,N,N,,,206,NORMAL,27,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 20,20,143,4/28/13,WEEK 20,11,Potassium (mmol/L),K,19,CHEM,4.3,4.3,0,3.4,5.4,1.264705882,0.796296296,1.264705882,0.796296296,,3.8,N,N,,,251,NORMAL,4.3,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 20,20,143,4/28/13,WEEK 20,11,Bilirubin (umol/L),BILI,21,CHEM,15.39,13.68,1.71,3,21,5.13,0.732857143,4.56,0.651428571,,16.11,N,N,,,239,NORMAL,15.39,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 20,20,143,4/28/13,WEEK 20,11,Alkaline Phosphatase (U/L),ALP,22,CHEM,57,80,-23,35,115,1.628571429,0.495652174,2.285714286,0.695652174,,115.5,N,N,,,234,NORMAL,57,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 20,20,143,4/28/13,WEEK 20,11,Alanine Aminotransferase (U/L),ALT,24,CHEM,29,36,-7,6,35,4.833333333,0.828571429,6,1.028571429,,26,N,N,,,235,NORMAL,29,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 20,20,143,4/28/13,WEEK 20,11,Aspartate Aminotransferase (U/L),AST,25,CHEM,32,38,-6,11,36,2.909090909,0.888888889,3.454545455,1.055555556,,26.5,N,N,,,237,NORMAL,32,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 24,24,168,5/23/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,5.1,4.3,0.8,3.4,5.4,1.5,0.944444444,1.264705882,0.796296296,,3.4,N,N,,Y,282,NORMAL,5.1,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,168,5/23/13,WEEK 24,12,Potassium (mmol/L),K,19,CHEM,5.1,4.3,0.8,3.4,5.4,1.5,0.944444444,1.264705882,0.796296296,,3.4,N,N,,Y,282,NORMAL,5.1,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 24,24,168,5/23/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,13.68,-1.71,3,21,3.99,0.57,4.56,0.651428571,,19.53,N,N,,Y,269,NORMAL,11.97,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,168,5/23/13,WEEK 24,12,Bilirubin (umol/L),BILI,21,CHEM,11.97,13.68,-1.71,3,21,3.99,0.57,4.56,0.651428571,,19.53,N,N,,Y,269,NORMAL,11.97,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 24,24,168,5/23/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,80,-25,35,115,1.571428571,0.47826087,2.285714286,0.695652174,Y,117.5,N,N,,Y,265,NORMAL,55,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,168,5/23/13,WEEK 24,12,Alkaline Phosphatase (U/L),ALP,22,CHEM,55,80,-25,35,115,1.571428571,0.47826087,2.285714286,0.695652174,Y,117.5,N,N,,Y,265,NORMAL,55,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 24,24,168,5/23/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,36,-11,6,35,4.166666667,0.714285714,6,1.028571429,,27.5,N,N,,Y,266,NORMAL,25,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,168,5/23/13,WEEK 24,12,Alanine Aminotransferase (U/L),ALT,24,CHEM,25,36,-11,6,35,4.166666667,0.714285714,6,1.028571429,,27.5,N,N,,Y,266,NORMAL,25,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 24,24,168,5/23/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,38,-10,11,36,2.545454545,0.777777778,3.454545455,1.055555556,,26,N,N,,Y,267,NORMAL,28,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y,End of Treatment,99,168,5/23/13,WEEK 24,12,Aspartate Aminotransferase (U/L),AST,25,CHEM,28,38,-10,11,36,2.545454545,0.777777778,3.454545455,1.055555556,,26,N,N,,Y,267,NORMAL,28,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 26,26,195,6/19/13,WEEK 26,13,Potassium (mmol/L),K,19,CHEM,4,4.3,-0.3,3.4,5.4,1.176470588,0.740740741,1.264705882,0.796296296,,4.1,N,N,,,317,NORMAL,4,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 26,26,195,6/19/13,WEEK 26,13,Bilirubin (umol/L),BILI,21,CHEM,13.68,13.68,0,3,21,4.56,0.651428571,4.56,0.651428571,,17.82,N,N,,,305,NORMAL,13.68,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 26,26,195,6/19/13,WEEK 26,13,Alkaline Phosphatase (U/L),ALP,22,CHEM,60,80,-20,35,115,1.714285714,0.52173913,2.285714286,0.695652174,,112.5,N,N,,,301,NORMAL,60,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 26,26,195,6/19/13,WEEK 26,13,Alanine Aminotransferase (U/L),ALT,24,CHEM,24,36,-12,6,35,4,0.685714286,6,1.028571429,,28.5,N,N,,,302,NORMAL,24,0,No
CDISCPILOT01,1388,01-704-1388,Placebo,0,Placebo,0,12/7/12,6/11/13,81,>80,3,WHITE,1,M,Y,,Y, Week 26,26,195,6/19/13,WEEK 26,13,Aspartate Aminotransferase (U/L),AST,25,CHEM,25,38,-13,11,36,2.272727273,0.694444444,3.454545455,1.055555556,,29,N,N,,,303,NORMAL,25,0,No
CDISCPILOT01,1435,01-704-1435,Placebo,0,Placebo,0,11/17/12,1/9/13,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-19,10/29/12,SCREENING 1,1,Potassium (mmol/L),K,19,CHEM,4,4,,3.4,5.4,1.176470588,0.740740741,1.176470588,0.740740741,,4.1,N,N,Y,,19,NORMAL,4,0,No
CDISCPILOT01,1435,01-704-1435,Placebo,0,Placebo,0,11/17/12,1/9/13,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-19,10/29/12,SCREENING 1,1,Bilirubin (umol/L),BILI,21,CHEM,10.26,10.26,,3,21,3.42,0.488571429,3.42,0.488571429,,21.24,N,N,Y,,6,NORMAL,10.26,0,No
CDISCPILOT01,1435,01-704-1435,Placebo,0,Placebo,0,11/17/12,1/9/13,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-19,10/29/12,SCREENING 1,1,Alkaline Phosphatase (U/L),ALP,22,CHEM,86,86,,35,115,2.457142857,0.747826087,2.457142857,0.747826087,,86.5,N,N,Y,,2,NORMAL,86,0,No
CDISCPILOT01,1435,01-704-1435,Placebo,0,Placebo,0,11/17/12,1/9/13,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-19,10/29/12,SCREENING 1,1,Alanine Aminotransferase (U/L),ALT,24,CHEM,13,13,,6,35,2.166666667,0.371428571,2.166666667,0.371428571,,39.5,N,N,Y,,3,NORMAL,13,0,No
CDISCPILOT01,1435,01-704-1435,Placebo,0,Placebo,0,11/17/12,1/9/13,74,65-80,2,WHITE,1,M,N,,Y, Baseline,0,-19,10/29/12,SCREENING 1,1,Aspa
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